标题
Structural basis for leucine sensing by the Sestrin2-mTORC1 pathway
作者
关键词
-
出版物
SCIENCE
Volume 351, Issue 6268, Pages 53-58
出版商
American Association for the Advancement of Science (AAAS)
发表日期
2016-01-01
DOI
10.1126/science.aad2087
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1
- (2015) S. Wang et al. SCIENCE
- Sestrin2 is a leucine sensor for the mTORC1 pathway
- (2015) R. L. Wolfson et al. SCIENCE
- Sestrins Function as Guanine Nucleotide Dissociation Inhibitors for Rag GTPases to Control mTORC1 Signaling
- (2014) Min Peng et al. CELL
- The Sestrins Interact with GATOR2 to Negatively Regulate the Amino-Acid-Sensing Pathway Upstream of mTORC1
- (2014) Lynne Chantranupong et al. Cell Reports
- Sestrins Inhibit mTORC1 Kinase Activation through the GATOR Complex
- (2014) Anita Parmigiani et al. Cell Reports
- Nutrients and growth factors in mTORC1 activation
- (2013) Alejo Efeyan et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- The Folliculin Tumor Suppressor Is a GAP for the RagC/D GTPases That Signal Amino Acid Levels to mTORC1
- (2013) Zhi-Yang Tsun et al. MOLECULAR CELL
- Signal integration by mTORC1 coordinates nutrient input with biosynthetic output
- (2013) Christian C. Dibble et al. NATURE CELL BIOLOGY
- Amino acid signalling upstream of mTOR
- (2013) Jenna L. Jewell et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- OptimizedE. coliexpression strain LOBSTR eliminates common contaminants from His-tag purification
- (2013) Kasper R. Andersen et al. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
- A Tumor Suppressor Complex with GAP Activity for the Rag GTPases That Signal Amino Acid Sufficiency to mTORC1
- (2013) L. Bar-Peled et al. SCIENCE
- Collaboration gets the most out of software
- (2013) Andrew Morin et al. eLife
- Ragulator Is a GEF for the Rag GTPases that Signal Amino Acid Levels to mTORC1
- (2012) Liron Bar-Peled et al. CELL
- mTOR Signaling in Growth Control and Disease
- (2012) Mathieu Laplante et al. CELL
- Regulation of TOR by small GTPases
- (2012) Raúl V Durán et al. EMBO REPORTS
- Overview of theCCP4 suite and current developments
- (2011) Martyn D. Winn et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- mTORC1 Senses Lysosomal Amino Acids Through an Inside-Out Mechanism That Requires the Vacuolar H+-ATPase
- (2011) R. Zoncu et al. SCIENCE
- Features and development ofCoot
- (2010) P. Emsley et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- PHENIX: a comprehensive Python-based system for macromolecular structure solution
- (2010) Paul D. Adams et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Ragulator-Rag Complex Targets mTORC1 to the Lysosomal Surface and Is Necessary for Its Activation by Amino Acids
- (2010) Yasemin Sancak et al. CELL
- mTOR: from growth signal integration to cancer, diabetes and ageing
- (2010) Roberto Zoncu et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Jalview Version 2--a multiple sequence alignment editor and analysis workbench
- (2009) A. M. Waterhouse et al. BIOINFORMATICS
- Sestrin 2 Is Not a Reductase for Cysteine Sulfinic Acid of Peroxiredoxins
- (2008) Hyun Ae Woo et al. ANTIOXIDANTS & REDOX SIGNALING
- Protein, amino acids and the control of food intake
- (2008) Mylène Potier et al. CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE
- Structural Evidence for Common Ancestry of the Nuclear Pore Complex and Vesicle Coats
- (2008) S. G. Brohawn et al. SCIENCE
- The Rag GTPases Bind Raptor and Mediate Amino Acid Signaling to mTORC1
- (2008) Y. Sancak et al. SCIENCE
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started