Leucine-enriched amino acids maintain peripheral mTOR-Rheb localization independent of myofibrillar protein synthesis and mTORC1 signaling postexercise

Leucine-Enriched Essential Amino Acids Improve Recovery from Post-Exercise Muscle Damage Independent of Increases in Integrated Myofibrillar Protein Synthesis in Young Men

(2020) Marcus Waskiw-Ford et al.   Nutrients

MOLECULAR REGULATION OF HUMAN SKELETAL MUSCLE PROTEIN SYNTHESIS IN RESPONSE TO EXERCISE AND NUTRIENTS: A COMPASS FOR OVERCOMING AGE-RELATED ANABOLIC RESISTANCE

(2019) Nathan Hodson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Skeletal muscle amino acid transporter and BCAT2 expression prior to and following interval running or resistance exercise in mode-specific trained males

(2018) Paul A. Roberson et al.   AMINO ACIDS

Whole egg, but not egg white, ingestion induces mTOR colocalization with the lysosome after resistance exercise

(2018) Sidney Abou Sawan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

The Importance of mTOR Trafficking for Human Skeletal Muscle Translational Control

(2018) Nathan Hodson et al.   EXERCISE AND SPORT SCIENCES REVIEWS

Characterisation of L-Type Amino Acid Transporter 1 (LAT1) Expression in Human Skeletal Muscle by Immunofluorescent Microscopy

(2017) Nathan Hodson et al.   Nutrients

Branched-Chain Amino Acid Ingestion Stimulates Muscle Myofibrillar Protein Synthesis following Resistance Exercise in Humans

(2017) Sarah R. Jackman et al.   Frontiers in Physiology

Resistance exercise initiates mechanistic target of rapamycin (mTOR) translocation and protein complex co-localisation in human skeletal muscle

(2017) Zhe Song et al.   Scientific Reports

Effects of leucine-enriched essential amino acid and whey protein bolus dosing upon skeletal muscle protein synthesis at rest and after exercise in older women

(2017) Daniel J. Wilkinson et al.   CLINICAL NUTRITION

Anabolic sensitivity of postprandial muscle protein synthesis to the ingestion of a protein-dense food is reduced in overweight and obese young adults

(2016) Joseph W Beals et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Activation of mTORC1 by leucine is potentiated by branched-chain amino acids and even more so by essential amino acids following resistance exercise

(2016) Marcus Moberg et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Leucine-Enriched Essential Amino Acids Augment Mixed Protein Synthesis, But Not Collagen Protein Synthesis, in Rat Skeletal Muscle after Downhill Running

(2016) Hiroyuki Kato et al.   Nutrients

Leucine does not affect mechanistic target of rapamycin complex 1 assembly but is required for maximal ribosomal protein s6 kinase 1 activity in human skeletal muscle following resistance exercise

(2015) William Apró et al.   FASEB JOURNAL

Sestrin2 is a leucine sensor for the mTORC1 pathway

(2015) R. L. Wolfson et al.   SCIENCE

Soy-dairy protein blend and whey protein ingestion after resistance exercise increases amino acid transport and transporter expression in human skeletal muscle

(2014) P. T. Reidy et al.   JOURNAL OF APPLIED PHYSIOLOGY

Application of the [γ-32P] ATP kinase assay to study anabolic signaling in human skeletal muscle

(2014) Chris McGlory et al.   JOURNAL OF APPLIED PHYSIOLOGY

CrossTalk proposal: The dominant mechanism causing disuse muscle atrophy is decreased protein synthesis

(2014) Stuart M. Phillips et al.   JOURNAL OF PHYSIOLOGY-LONDON

Protein Ingestion to Stimulate Myofibrillar Protein Synthesis Requires Greater Relative Protein Intakes in Healthy Older Versus Younger Men

(2014) D. R. Moore et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

The Catalytic Subunit of the System L1 Amino Acid Transporter (Slc7a5) Facilitates Nutrient Signalling in Mouse Skeletal Muscle

(2014) Nadège Poncet et al.   PLoS One

The Sestrins Interact with GATOR2 to Negatively Regulate the Amino-Acid-Sensing Pathway Upstream of mTORC1

(2014) Lynne Chantranupong et al.   Cell Reports

Role of amino acid transporters in amino acid sensing

(2013) Peter M Taylor   AMERICAN JOURNAL OF CLINICAL NUTRITION

Myofibrillar muscle protein synthesis rates subsequent to a meal in response to increasing doses of whey protein at rest and after resistance exercise

(2013) Oliver C Witard et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Leucine supplementation of a low-protein mixed macronutrient beverage enhances myofibrillar protein synthesis in young men: a double-blind, randomized trial

(2013) Tyler A Churchward-Venne et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Absence of leucine in an essential amino acid supplement reduces activation of mTORC1 signalling following resistance exercise in young females

(2013) Marcus Moberg et al.   Applied Physiology Nutrition and Metabolism

Eccentric contractions increase the phosphorylation of tuberous sclerosis complex-2 (TSC2) and alter the targeting of TSC2 and the mechanistic target of rapamycin to the lysosome

(2013) Brittany L. Jacobs et al.   JOURNAL OF PHYSIOLOGY-LONDON

Effects of leucine and its metabolite β-hydroxy-β-methylbutyrate on human skeletal muscle protein metabolism

(2013) D. J. Wilkinson et al.   JOURNAL OF PHYSIOLOGY-LONDON

Dose-dependent responses of myofibrillar protein synthesis with beef ingestion are enhanced with resistance exercise in middle-aged men

(2012) Meghann J. Robinson et al.   Applied Physiology Nutrition and Metabolism

Resistance exercise enhances myofibrillar protein synthesis with graded intakes of whey protein in older men

(2012) Yifan Yang et al.   BRITISH JOURNAL OF NUTRITION

Aging differentially affects human skeletal muscle amino acid transporter expression when essential amino acids are ingested after exercise

(2012) Jared M. Dickinson et al.   CLINICAL NUTRITION

Supplementation of a suboptimal protein dose with leucine or essential amino acids: effects on myofibrillar protein synthesis at rest and following resistance exercise in men

(2012) Tyler A. Churchward-Venne et al.   JOURNAL OF PHYSIOLOGY-LONDON

Rapid aminoacidemia enhances myofibrillar protein synthesis and anabolic intramuscular signaling responses after resistance exercise

(2011) D. W. West et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Skeletal muscle amino acid transporter expression is increased in young and older adults following resistance exercise

(2011) Micah J. Drummond et al.   JOURNAL OF APPLIED PHYSIOLOGY

Mammalian Target of Rapamycin Complex 1 Activation Is Required for the Stimulation of Human Skeletal Muscle Protein Synthesis by Essential Amino Acids

(2011) Jared M. Dickinson et al.   JOURNAL OF NUTRITION

Suction-modified Bergström muscle biopsy technique: Experience with 13,500 procedures

(2011) Mark A. Tarnopolsky et al.   MUSCLE & NERVE

Lysosomal positioning coordinates cellular nutrient responses

(2011) Viktor I. Korolchuk et al.   NATURE CELL BIOLOGY

An increase in essential amino acid availability upregulates amino acid transporter expression in human skeletal muscle

(2010) Micah J. Drummond et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Reversible Ponceau staining as a loading control alternative to actin in Western blots

(2010) Isabel Romero-Calvo et al.   ANALYTICAL BIOCHEMISTRY

Ragulator-Rag Complex Targets mTORC1 to the Lysosomal Surface and Is Necessary for Its Activation by Amino Acids

(2010) Yasemin Sancak et al.   CELL

Tertiary active transport of amino acids reconstituted by coexpression of System A and L transporters in Xenopus oocytes

(2009) Fiona E. Baird et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Distinct anabolic signalling responses to amino acids in C2C12 skeletal muscle cells

(2009) Philip J. Atherton et al.   AMINO ACIDS

Rapamycin administration in humans blocks the contraction-induced increase in skeletal muscle protein synthesis

(2009) Micah J. Drummond et al.   JOURNAL OF PHYSIOLOGY-LONDON

Differential stimulation of myofibrillar and sarcoplasmic protein synthesis with protein ingestion at rest and after resistance exercise

(2009) Daniel R. Moore et al.   JOURNAL OF PHYSIOLOGY-LONDON

Ingested protein dose response of muscle and albumin protein synthesis after resistance exercise in young men

(2008) Daniel R Moore et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Exercise training and protein metabolism: influences of contraction, protein intake, and sex-based differences

(2008) Nicholas A. Burd et al.   JOURNAL OF APPLIED PHYSIOLOGY

The Rag GTPases Bind Raptor and Mediate Amino Acid Signaling to mTORC1

(2008) Y. Sancak et al.   SCIENCE