Macrophage Involvement in Aging-Associated Skeletal Muscle Regeneration

Transcriptional reprogramming of skeletal muscle stem cells by the niche environment

(2023) Felicia Lazure et al.   Nature Communications

Pathogenesis of sarcopenia and the relationship with fat mass: descriptive review

(2022) Chun‐wei Li et al.   Journal of Cachexia Sarcopenia and Muscle

Three tissue resident macrophage subsets coexist across organs with conserved origins and life cycles

(2022) Sarah A. Dick et al.   Science Immunology

Plin2-mediated lipid droplet mobilization accelerates exit from pluripotency by lipidomic remodeling and histone acetylation

(2022) Yi Wu et al.   CELL DEATH AND DIFFERENTIATION

Fasting induces a highly resilient deep quiescent state in muscle stem cells via ketone body signaling

(2022) Daniel I. Benjamin et al.   Cell Metabolism

Glycoprotein nonmetastatic melanoma protein B regulates lysosomal integrity and lifespan of senescent cells

(2022) Masayoshi Suda et al.   Scientific Reports

Heterogeneous Skeletal Muscle Cell and Nucleus Populations Identified by Single-Cell and Single-Nucleus Resolution Transcriptome Assays

(2022) Katherine Williams et al.   Frontiers in Genetics

Adaptive Remodeling of the Neuromuscular Junction with Aging

(2022) Michael R. Deschenes et al.   Cells

Exercise-mediated reinnervation of skeletal muscle in elderly people: An update

(2022) Claudia Coletti et al.   European Journal of Translational Myology

Aging is associated with an altered macrophage response during human skeletal muscle regeneration

(2022) Mohadeseh Ahmadi et al.   EXPERIMENTAL GERONTOLOGY

Macrophage immunomodulation accelerates skeletal muscle functional recovery in aged mice following disuse atrophy

(2022) Patrick J. Ferrara et al.   JOURNAL OF APPLIED PHYSIOLOGY

Single-cell analysis of skeletal muscle macrophages reveals age-associated functional subpopulations

(2022) Linda K Krasniewski et al.   eLife

Elevated CD47 is a hallmark of dysfunctional aged muscle stem cells that can be targeted to augment regeneration

(2022) Ermelinda Porpiglia et al.   Cell Stem Cell

Senescence atlas reveals an aged-like inflamed niche that blunts muscle regeneration

(2022) Victoria Moiseeva et al.   NATURE

Depletion of CD206+ M2-like macrophages induces fibro-adipogenic progenitors activation and muscle regeneration

(2022) Allah Nawaz et al.   Nature Communications

Aged Skeletal Muscle Retains the Ability to Remodel Extracellular Matrix for Degradation of Collagen Deposition after Muscle Injury

(2021) Wan-Jing Chen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Macrophages provide a transient muscle stem cell niche via NAMPT secretion

(2021) Dhanushika Ratnayake et al.   NATURE

Perspectives on skeletal muscle stem cells

(2021) F. Relaix et al.   Nature Communications

Putting the brakes on phagocytosis: “don't‐eat‐me” signaling in physiology and disease

(2021) Shannon M Kelley et al.   EMBO REPORTS

Extensive remodeling of the extracellular matrix during aging contributes to age-dependent impairments of muscle stem cell functionality

(2021) Svenja C. Schüler et al.   Cell Reports

Macrophages: The Good, the Bad, and the Gluttony

(2021) Ewan A. Ross et al.   Frontiers in Immunology

Age-Related Alterations at Neuromuscular Junction: Role of Oxidative Stress and Epigenetic Modifications

(2021) Gabriella Dobrowolny et al.   Cells

Characterization of the Skeletal Muscle Secretome Reveals a Role for Extracellular Vesicles and IL1α/IL1β in Restricting Fibro/Adipogenic Progenitor Adipogenesis

(2021) Simone Vumbaca et al.   Biomolecules

Peripheral Nerve Impairment in a Mouse Model of Alzheimer’s Disease

(2021) Alessio Torcinaro et al.   Brain Sciences

Stem cell aging in the skeletal muscle: The importance of communication

(2021) Xiaotong Hong et al.   AGEING RESEARCH REVIEWS

Deletion of SA β‐Gal+ cells using senolytics improves muscle regeneration in old mice

(2021) Cory M. Dungan et al.   AGING CELL

Fibro-adipogenic progenitors in skeletal muscle homeostasis, regeneration and diseases

(2021) Thomas Molina et al.   Open Biology

The right time for senescence

(2021) Diogo Paramos-de-Carvalho et al.   eLife

Multiomic profiling of the liver across diets and age in a diverse mouse population

(2021) Evan G. Williams et al.   Cell Systems

Macrophages in skeletal muscle aging

(2020) Chang-Yi Cui et al.   Aging-US

Mechanisms Regulating Muscle Regeneration: Insights into the Interrelated and Time-Dependent Phases of Tissue Healing

(2020) Laura Forcina et al.   Cells

Heterogeneous origins and functions of mouse skeletal muscle-resident macrophages

(2020) Xingyu Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dissecting Murine Muscle Stem Cell Aging through Regeneration Using Integrative Genomic Analysis

(2020) Anna Shcherbina et al.   Cell Reports

Age‐related decline of interferon‐gamma responses in macrophage impairs satellite cell proliferation and regeneration

(2020) Congcong Zhang et al.   Journal of Cachexia Sarcopenia and Muscle

Tissue Stem Cells: Architects of Their Niches

(2020) Elaine Fuchs et al.   Cell Stem Cell

Senescent cells and macrophages: key players for regeneration?

(2020) Sonia S. Elder et al.   Open Biology

Metabolic Alterations in Aging Macrophages: Ingredients for Inflammaging?

(2019) Adriaan A. van Beek et al.   TRENDS IN IMMUNOLOGY

Two distinct interstitial macrophage populations coexist across tissues in specific subtissular niches

(2019) Svetoslav Chakarov et al.   SCIENCE

Aging Disrupts Muscle Stem Cell Function by Impairing Matricellular WISP1 Secretion from Fibro-Adipogenic Progenitors

(2019) Laura Lukjanenko et al.   Cell Stem Cell

Mechanisms of lymphoma clearance induced by high-dose alkylating agents

(2019) Chen Lossos et al.   Cancer Discovery

Lipid-Associated Macrophages Control Metabolic Homeostasis in a Trem2-Dependent Manner

(2019) Diego Adhemar Jaitin et al.   CELL

Skewed macrophage polarization in aging skeletal muscle

(2019) Chang‐Yi Cui et al.   AGING CELL

Aging- and obesity-related peri-muscular adipose tissue accelerates muscle atrophy

(2019) Shunshun Zhu et al.   PLoS One

Fibro–Adipogenic Progenitors Cross-Talk in Skeletal Muscle: The Social Network

(2019) Beatrice Biferali et al.   Frontiers in Physiology

Non-classical tissue monocytes and two functionally distinct populations of interstitial macrophages populate the mouse lung

(2019) Joey Schyns et al.   Nature Communications

Understanding muscle regenerative decline with aging: new approaches to bring back youthfulness to aged stem cells

(2019) Pura Muñoz‐Cánoves et al.   FEBS Journal

Plasma proteomic signature of age in healthy humans

(2018) Toshiko Tanaka et al.   AGING CELL

Macrophage plasticity, polarization, and function in health and disease

(2018) Abbas Shapouri-Moghaddam et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Macrophage Depletion Ameliorates Peripheral Neuropathy in Aging Mice

(2018) Xidi Yuan et al.   JOURNAL OF NEUROSCIENCE

S100A8/A9 in Inflammation

(2018) Siwen Wang et al.   Frontiers in Immunology

Reciprocal signalling by Notch–Collagen V–CALCR retains muscle stem cells in their niche

(2018) Meryem B. Baghdadi et al.   NATURE

Dynamics of cellular states of fibro-adipogenic progenitors during myogenesis and muscular dystrophy

(2018) Barbora Malecova et al.   Nature Communications

Sarcopenia and Muscle Functions at Various Stages of Alzheimer Disease

(2018) Yusuke Ogawa et al.   Frontiers in Neurology

Incorporation of macrophages into engineered skeletal muscle enables enhanced muscle regeneration

(2018) Mark Juhas et al.   Nature Biomedical Engineering

Nature and nurture of tissue-specific macrophage phenotypes

(2018) Marten A. Hoeksema et al.   ATHEROSCLEROSIS

Hyaluronan Receptor LYVE-1-Expressing Macrophages Maintain Arterial Tone through Hyaluronan-Mediated Regulation of Smooth Muscle Cell Collagen

(2018) Hwee Ying Lim et al.   IMMUNITY

Functional muscle recovery with nanoparticle-directed M2 macrophage polarization in mice

(2018) Theresa M. Raimondo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IL-1β- and IL-4-polarized macrophages have opposite effects on adipogenesis of intramuscular fibro-adipogenic progenitors in humans

(2018) C. Moratal et al.   Scientific Reports

F4/80+ Macrophages Contribute to Clearance of Senescent Cells in the Mouse Postpartum Uterus

(2017) Mahiro Egashira et al.   ENDOCRINOLOGY

Adipose tissue macrophages develop from bone marrow–independent progenitors in Xenopus laevis and mouse

(2017) Syed F. Hassnain Waqas et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Macrophage-released ADAMTS1 promotes muscle stem cell activation

(2017) Hongqing Du et al.   Nature Communications

Skeletal muscle regeneration involves macrophage-myoblast bonding

(2017) Laura Cristina Ceafalan et al.   Cell Adhesion & Migration

Morphological Regeneration and Functional Recovery of Neuromuscular Junctions after Tourniquet-Induced Injuries in Mouse Hindlimb

(2017) Huiyin Tu et al.   Frontiers in Physiology

Skeletal Muscle Thermogenesis and Its Role in Whole Body Energy Metabolism

(2017) Muthu Periasamy et al.   Diabetes & Metabolism Journal

Monocyte Conversion During Inflammation and InjuryHighlights

(2016) Rachel M. Kratofil et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Tissue-Resident Macrophage Ontogeny and Homeostasis

(2016) Florent Ginhoux et al.   IMMUNITY

Age-Related Change in Mobility: Perspectives From Life Course Epidemiology and Geroscience

(2016) Luigi Ferrucci et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Naturally occurring p16Ink4a-positive cells shorten healthy lifespan

(2016) Darren J. Baker et al.   NATURE

Satellite Cell Heterogeneity in Skeletal Muscle Homeostasis

(2016) Matthew T. Tierney et al.   TRENDS IN CELL BIOLOGY

Cerebrospinal fluid soluble TREM2 in aging and Alzheimer’s disease

(2016) Kristi Henjum et al.   Alzheimers Research & Therapy

Fatty Infiltration of Skeletal Muscle: Mechanisms and Comparisons with Bone Marrow Adiposity

(2016) Mark W. Hamrick et al.   Frontiers in Endocrinology

Age dependent increase in the levels of osteopontin inhibits skeletal muscle regeneration

(2016) Preeti Paliwal et al.   Aging-US

Apoptosis and necrosis mediate skeletal muscle fiber loss in age-induced mitochondrial enzymatic abnormalities

(2015) Nashwa Cheema et al.   AGING CELL

Increases of M2a macrophages and fibrosis in aging muscle are influenced by bone marrow aging and negatively regulated by muscle-derived nitric oxide

(2015) Ying Wang et al.   AGING CELL

Muscle as a “Mediator” of Systemic Metabolism

(2015) Kedryn K. Baskin et al.   Cell Metabolism

The pancreas anatomy conditions the origin and properties of resident macrophages

(2015) Boris Calderon et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Nilotinib reduces muscle fibrosis in chronic muscle injury by promoting TNF-mediated apoptosis of fibro/adipogenic progenitors

(2015) Dario R Lemos et al.   NATURE MEDICINE

Muscle stem cell aging: regulation and rejuvenation

(2015) Pedro Sousa-Victor et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Skeletal Muscle: A Brief Review of Structure and Function

(2014) Walter R. Frontera et al.   CALCIFIED TISSUE INTERNATIONAL

Tissue-Resident Macrophage Enhancer Landscapes Are Shaped by the Local Microenvironment

(2014) Yonit Lavin et al.   CELL

Environment Drives Selection and Function of Enhancers Controlling Tissue-Specific Macrophage Identities

(2014) David Gosselin et al.   CELL

Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

(2014) Peter J. Murray et al.   IMMUNITY

Geriatric muscle stem cells switch reversible quiescence into senescence

(2014) Pedro Sousa-Victor et al.   NATURE

Rejuvenation of the muscle stem cell population restores strength to injured aged muscles

(2014) Benjamin D Cosgrove et al.   NATURE MEDICINE

S100A9 Knockout Decreases the Memory Impairment and Neuropathology in Crossbreed Mice of Tg2576 and S100A9 Knockout Mice Model

(2014) Hee Jin Kim et al.   PLoS One

Age-related and disease-related muscle loss: the effect of diabetes, obesity, and other diseases

(2014) Rita Rastogi Kalyani et al.   Lancet Diabetes & Endocrinology

Macrophage: SHIP of Immunity

(2014) Charles D. Mills et al.   Frontiers in Immunology

Metabolism via Arginase or Nitric Oxide Synthase: Two Competing Arginine Pathways in Macrophages

(2014) Meera Rath et al.   Frontiers in Immunology

Non-Cell-Autonomous Tumor Suppression by p53

(2013) Amaia Lujambio et al.   CELL

Type 2 Innate Signals Stimulate Fibro/Adipogenic Progenitors to Facilitate Muscle Regeneration

(2013) Jose E. Heredia et al.   CELL

The decline in skeletal muscle mass with aging is mainly attributed to a reduction in type II muscle fiber size

(2013) Rachel Nilwik et al.   EXPERIMENTAL GERONTOLOGY

Macrophage biology in development, homeostasis and disease

(2013) Thomas A. Wynn et al.   NATURE

Corticosteroid treatment of Alzheimer's disease: is S100A9/Mrp14 a key target?

(2013) Fuyuki Kametani   NEUROBIOLOGY OF AGING

Aging, Cellular Senescence, and Cancer

(2012) Judith Campisi   Annual Review of Physiology

Inflammation and Lipid Signaling in the Etiology of Insulin Resistance

(2012) Christopher K. Glass et al.   Cell Metabolism

Satellite cells are essential for skeletal muscle regeneration: the cell on the edge returns centre stage

(2012) F. Relaix et al.   DEVELOPMENT

Non-Classical P38 Map Kinase Functions: Cell Cycle Checkpoints and Survival

(2012) Tina M. Thornton et al.   International Journal of Biological Sciences

Effects of aging and exercise training on skeletal muscle blood flow and resistance artery morphology

(2012) Bradley J. Behnke et al.   JOURNAL OF APPLIED PHYSIOLOGY

IL-10 Triggers Changes in Macrophage Phenotype That Promote Muscle Growth and Regeneration

(2012) B. Deng et al.   JOURNAL OF IMMUNOLOGY

Mrp14 Deficiency Ameliorates Amyloid   Burden by Increasing Microglial Phagocytosis and Modulation of Amyloid Precursor Protein Processing

(2012) M. P. Kummer et al.   JOURNAL OF NEUROSCIENCE

Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages

(2012) Emmanuel L Gautier et al.   NATURE IMMUNOLOGY

The Role of S100a9 in the Pathogenesis of Alzheimer’s Disease: The Therapeutic Effects of S100a9 Knockdown or Knockout

(2012) Keun-A Chang et al.   Neurodegenerative Diseases

MRP14 (S100A9) Protein Interacts with Alzheimer Beta-Amyloid Peptide and Induces Its Fibrillization

(2012) Ce Zhang et al.   PLoS One

Macrophage Mal1 Deficiency Suppresses Atherosclerosis in Low-Density Lipoprotein Receptor–Null Mice by Activating Peroxisome Proliferator-Activated Receptor-γ–Regulated Genes

(2011) Vladimir R. Babaev et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Ageing prolongs inflammatory marker expression in regenerating rat skeletal muscles after injury

(2011) Chris van der Poel et al.   Journal of Inflammation-London

Alternatively activated macrophages produce catecholamines to sustain adaptive thermogenesis

(2011) Khoa D. Nguyen et al.   NATURE

Senescence surveillance of pre-malignant hepatocytes limits liver cancer development

(2011) Tae-Won Kang et al.   NATURE

Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders

(2011) Darren J. Baker et al.   NATURE

Structural, biochemical, cellular, and functional changes in skeletal muscle extracellular matrix with aging

(2011) T. W. Kragstrup et al.   SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS

Synaptic Pruning by Microglia Is Necessary for Normal Brain Development

(2011) R. C. Paolicelli et al.   SCIENCE

Reduced Lean Mass in Early Alzheimer Disease and Its Association With Brain Atrophy

(2010) Jeffrey M. Burns et al.   ARCHIVES OF NEUROLOGY

Muscle injury activates resident fibro/adipogenic progenitors that facilitate myogenesis

(2010) Aaron W. B. Joe et al.   NATURE CELL BIOLOGY

Apolipoprotein E: From lipid transport to neurobiology

(2010) Paul S. Hauser et al.   PROGRESS IN LIPID RESEARCH

Senescent Stromal-Derived Osteopontin Promotes Preneoplastic Cell Growth

(2009) E. Pazolli et al.   CANCER RESEARCH

CD47 Is Upregulated on Circulating Hematopoietic Stem Cells and Leukemia Cells to Avoid Phagocytosis

(2009) Siddhartha Jaiswal et al.   CELL

The biology of satellite cells and telomeres in human skeletal muscle: effects of aging and physical activity

(2009) F. Kadi et al.   SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS

Stem Cell Review Series: Aging of the skeletal muscle stem cell niche

(2008) Suchitra D. Gopinath et al.   AGING CELL

Emigration of monocyte-derived cells to lymph nodes during resolution of inflammation and its failure in atherosclerosis

(2008) Gwendalyn J Randolph   CURRENT OPINION IN LIPIDOLOGY

Suppression of macrophage functions impairs skeletal muscle regeneration with severe fibrosis

(2008) M SEGAWA et al.   EXPERIMENTAL CELL RESEARCH

Macrophage activation and polarization

(2007) Fernando Oneissi Martinez   Frontiers in Bioscience-Landmark