标题
Multiomic profiling of the liver across diets and age in a diverse mouse population
作者
关键词
aging, multiomics, proteomics, genetic reference population, liver, time course, gene-by-environment interaction, GxE, causal inference, network biology, multivariate analysis
出版物
Cell Systems
Volume 13, Issue 1, Pages 43-57.e6
出版商
Elsevier BV
发表日期
2021-10-19
DOI
10.1016/j.cels.2021.09.005
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- A Platform for Experimental Precision Medicine: The Extended BXD Mouse Family
- (2021) David G. Ashbrook et al. Cell Systems
- Stabilizing variable selection and regression
- (2021) Niklas Pfister et al. Annals of Applied Statistics
- Diagnostics and correction of batch effects in large‐scale proteomic studies: a tutorial
- (2021) Jelena Čuklina et al. Molecular Systems Biology
- Lysosome activity is modulated by multiple longevity pathways and is important for lifespan extension in C. elegans
- (2020) Yanan Sun et al. eLife
- Strategies to enable large-scale proteomics for reproducible research
- (2020) Rebecca C. Poulos et al. Nature Communications
- A Customizable Analysis Flow in Integrative Multi-Omics
- (2020) Samuel M. Lancaster et al. Biomolecules
- Examination of the Dimensions of Biological Age
- (2019) S. Michal Jazwinski et al. Frontiers in Genetics
- Multi-omic measurements of heterogeneity in HeLa cells across laboratories
- (2019) Yansheng Liu et al. NATURE BIOTECHNOLOGY
- Proteostasis collapse is a driver of cell aging and death
- (2019) Mantu Santra et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Matrisome during Aging and Longevity: A Systems-Level Approach toward Defining Matreotypes Promoting Healthy Aging
- (2019) Collin Yvès Ewald GERONTOLOGY
- Cross-sectional studies - what are they good for?
- (2018) Ulrik S. Kesmodel ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA
- An epigenetic biomarker of aging for lifespan and healthspan
- (2018) Morgan E. Levine et al. Aging-US
- Genetic cartography of longevity in humans and mice: Current landscape and horizons
- (2018) Michael Hook et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- High-Fat Diets Alter the Modulatory Effects of Xenobiotics on Cytochrome P450 Activities
- (2018) Natalie C. Sadler et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Insulin Signaling Regulates Oocyte Quality Maintenance with Age via Cathepsin B Activity
- (2018) Nicole M. Templeman et al. CURRENT BIOLOGY
- Quantifying and Localizing the Mitochondrial Proteome Across Five Tissues in A Mouse Population
- (2018) Evan Graehl Williams et al. MOLECULAR & CELLULAR PROTEOMICS
- Data‐independent acquisition‐based SWATH‐MS for quantitative proteomics: a tutorial
- (2018) Christina Ludwig et al. Molecular Systems Biology
- Large-scale investigation of the reasons why potentially important genes are ignored
- (2018) Thomas Stoeger et al. PLOS BIOLOGY
- R/qtl2: Software for Mapping Quantitative Trait Loci with High-Dimensional Data and Multi-parent Populations
- (2018) Karl W. Broman et al. GENETICS
- CORUM: the comprehensive resource of mammalian protein complexes—2019
- (2018) Madalina Giurgiu et al. NUCLEIC ACIDS RESEARCH
- What have we learned on aging from omics studies?
- (2017) Alessandro Cellerino et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- NADPH oxidase-mediated redox signaling promotes oxidative stress resistance and longevity through memo-1 in C. elegans
- (2017) Collin Yvès Ewald et al. eLife
- The Mitochondrial Basis of Aging and Age-Related Disorders
- (2017) Sarika Srivastava Genes
- Lysosomal cathepsins and their regulation in aging and neurodegeneration
- (2016) Veronika Stoka et al. AGEING RESEARCH REVIEWS
- Defining the consequences of genetic variation on a proteome-wide scale
- (2016) Joel M. Chick et al. NATURE
- Methods for causal inference from gene perturbation experiments and validation
- (2016) Nicolai Meinshausen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Systems proteomics of liver mitochondria function
- (2016) E. G. Williams et al. SCIENCE
- Proteome-wide Changes in Protein Turnover Rates in C. elegans Models of Longevity and Age-Related Disease
- (2016) Marieke Visscher et al. Cell Reports
- Age modifies respiratory complex I and protein homeostasis in a muscle type-specific manner
- (2015) Shane E. Kruse et al. AGING CELL
- The Biology of Proteostasis in Aging and Disease
- (2015) Johnathan Labbadia et al. Annual Review of Biochemistry
- 2016 update of the PRIDE database and its related tools
- (2015) Juan Antonio Vizcaíno et al. NUCLEIC ACIDS RESEARCH
- Age and Cancer Risk
- (2014) Mary C. White et al. AMERICAN JOURNAL OF PREVENTIVE MEDICINE
- OpenSWATH enables automated, targeted analysis of data-independent acquisition MS data
- (2014) Hannes L Röst et al. NATURE BIOTECHNOLOGY
- A repository of assays to quantify 10,000 human proteins by SWATH-MS
- (2014) George Rosenberger et al. Scientific Data
- Collagenase-resistant collagen promotes mouse aging and vascular cell senescence
- (2013) Faran Vafaie et al. AGING CELL
- Integral Membrane Proteins and Bilayer Proteomics
- (2013) Julian P. Whitelegge ANALYTICAL CHEMISTRY
- Mitonuclear protein imbalance as a conserved longevity mechanism
- (2013) Riekelt H. Houtkooper et al. NATURE
- The Caenorhabditis elegans Lifespan Machine
- (2013) Nicholas Stroustrup et al. NATURE METHODS
- DNA methylation age of human tissues and cell types
- (2013) Steve Horvath GENOME BIOLOGY
- Systems Genetics of Metabolism: The Use of the BXD Murine Reference Panel for Multiscalar Integration of Traits
- (2012) Pénélope A. Andreux et al. CELL
- NDUFA4 Is a Subunit of Complex IV of the Mammalian Electron Transport Chain
- (2012) Eduardo Balsa et al. Cell Metabolism
- Targeted Data Extraction of the MS/MS Spectra Generated by Data-independent Acquisition: A New Concept for Consistent and Accurate Proteome Analysis
- (2012) Ludovic C. Gillet et al. MOLECULAR & CELLULAR PROTEOMICS
- Impact of caloric restriction on health and survival in rhesus monkeys from the NIA study
- (2012) Julie A. Mattison et al. NATURE
- Wisdom of crowds for robust gene network inference
- (2012) Daniel Marbach et al. NATURE METHODS
- High-Throughput, Accurate Mass Metabolome Profiling of Cellular Extracts by Flow Injection–Time-of-Flight Mass Spectrometry
- (2011) Tobias Fuhrer et al. ANALYTICAL CHEMISTRY
- Prioritizing candidate disease genes by network-based boosting of genome-wide association data
- (2011) I. Lee et al. GENOME RESEARCH
- The metabolic footprint of aging in mice
- (2011) Riekelt H. Houtkooper et al. Scientific Reports
- Genetic dissection of dietary restriction in mice supports the metabolic efficiency model of life extension
- (2010) Brad A. Rikke et al. EXPERIMENTAL GERONTOLOGY
- Stability selection
- (2010) Nicolai Meinshausen et al. JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY
- Accurate Quantification of More Than 4000 Mouse Tissue Proteins Reveals Minimal Proteome Changes During Aging
- (2010) Dirk M. Walther et al. MOLECULAR & CELLULAR PROTEOMICS
- Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
- (2009) Da Wei Huang et al. Nature Protocols
- Cathepsin D—Many functions of one aspartic protease
- (2008) Petr Benes et al. CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started