Plin2-mediated lipid droplet mobilization accelerates exit from pluripotency by lipidomic remodeling and histone acetylation

Lipid droplets in mammalian eggs are utilized during embryonic diapause

(2021) Roberta Arena et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Histone Acetyltransferases and Stem Cell Identity

(2021) Ruicen He et al.   Cancers

Regulatory T cell differentiation is controlled by αKG-induced alterations in mitochondrial metabolism and lipid homeostasis

(2021) Maria I. Matias et al.   Cell Reports

Metabolic Control over mTOR-Dependent Diapause-like State

(2020) Abdiasis M. Hussein et al.   DEVELOPMENTAL CELL

The cell biology of mitochondrial membrane dynamics

(2020) Marta Giacomello et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Nicotinamide adenine dinucleotide induces a bivalent metabolism and maintains pluripotency in human embryonic stem cells

(2020) Jarmon G. Lees et al.   STEM CELLS

Histone Acetyltransferase MOF Blocks Acquisition of Quiescence in Ground-State ESCs through Activating Fatty Acid Oxidation

(2020) Le Tran Phuc Khoa et al.   Cell Stem Cell

Mitochondrial PE potentiates respiratory enzymes to amplify skeletal muscle aerobic capacity

(2019) Timothy D. Heden et al.   Science Advances

Synthesis and maintenance of lipid droplets are essential for mouse preimplantation embryonic development

(2019) Ryutaro Aizawa et al.   DEVELOPMENT

Lipid droplet‐dependent fatty acid metabolism controls the immune suppressive phenotype of tumor‐associated macrophages

(2019) Hao Wu et al.   EMBO Molecular Medicine

Phospholipid remodeling is critical for stem cell pluripotency by facilitating mesenchymal-to-epithelial transition

(2019) Yi Wu et al.   Science Advances

Development of a High Coverage Pseudotargeted Lipidomics Method Based on Ultra-High Performance Liquid Chromatography–Mass Spectrometry

(2018) Qiuhui Xuan et al.   ANALYTICAL CHEMISTRY

Metabolism in Pluripotent Stem Cells and Early Mammalian Development

(2018) Jin Zhang et al.   Cell Metabolism

Forced lipophagy reveals that lipid droplets are required for early embryonic development in mouse

(2018) Takayuki Tatsumi et al.   DEVELOPMENT

Mitochondria and the dynamic control of stem cell homeostasis

(2018) Pawel Lisowski et al.   EMBO REPORTS

Metabolism in pluripotency: Both driver and passenger?

(2018) Perrine Dahan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metabolomics activity screening for identifying metabolites that modulate phenotype

(2018) Carlos Guijas et al.   NATURE BIOTECHNOLOGY

Mitochondrial Dynamics Is Critical for the Full Pluripotency and Embryonic Developmental Potential of Pluripotent Stem Cells

(2018) Xiuying Zhong et al.   Cell Metabolism

Dynamics and functions of lipid droplets

(2018) James A. Olzmann et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Perilipins: a diversity of intracellular lipid droplet proteins

(2017) Hiroyuki Itabe et al.   Lipids in Health and Disease

AMPK-dependent phosphorylation of lipid droplet protein PLIN2 triggers its degradation by CMA

(2016) Susmita Kaushik et al.   Autophagy

α-Ketoglutarate Accelerates the Initial Differentiation of Primed Human Pluripotent Stem Cells

(2016) Tara TeSlaa et al.   Cell Metabolism

Psat1-Dependent Fluctuations in α-Ketoglutarate Affect the Timing of ESC Differentiation

(2016) In-Young Hwang et al.   Cell Metabolism

The role of fatty acid β-oxidation in lymphangiogenesis

(2016) Brian W. Wong et al.   NATURE

Mitochondrial Cristae: Where Beauty Meets Functionality

(2016) Sara Cogliati et al.   TRENDS IN BIOCHEMICAL SCIENCES

Lipids Reprogram Metabolism to Become a Major Carbon Source for Histone Acetylation

(2016) Eoin McDonnell et al.   Cell Reports

Glial Lipid Droplets and ROS Induced by Mitochondrial Defects Promote Neurodegeneration

(2015) Lucy Liu et al.   CELL

Glycolysis-Mediated Changes in Acetyl-CoA and Histone Acetylation Control the Early Differentiation of Embryonic Stem Cells

(2015) Arieh Moussaieff et al.   Cell Metabolism

Acetyl Coenzyme A: A Central Metabolite and Second Messenger

(2015) Federico Pietrocola et al.   Cell Metabolism

Protein Lysine Acetylation by p300/CBP

(2015) Beverley M. Dancy et al.   CHEMICAL REVIEWS

Expanding Roles for Lipid Droplets

(2015) Michael A. Welte   CURRENT BIOLOGY

The metabolome regulates the epigenetic landscape during naive-to-primed human embryonic stem cell transition

(2015) Henrik Sperber et al.   NATURE CELL BIOLOGY

Degradation of lipid droplet-associated proteins by chaperone-mediated autophagy facilitates lipolysis

(2015) Susmita Kaushik et al.   NATURE CELL BIOLOGY

Srebp-1 Interacts with c-Myc to Enhance Somatic Cell Reprogramming

(2015) Yi Wu et al.   STEM CELLS

Through a Clear Cell, Darkly: HIF2 /PLIN2-Maintained Fat Droplets Protect ccRCCs from ER Stress

(2015) J. Sim et al.   Cancer Discovery

Drosophila Lipid Droplets Buffer the H2Av Supply to Protect Early Embryonic Development

(2014) Zhihuan Li et al.   CURRENT BIOLOGY

Pleiotropic regulation of mitochondrial function by adipose triglyceride lipase-mediated lipolysis

(2013) Dagmar Kratky et al.   BIOCHIMIE

Lipid Transport between the Endoplasmic Reticulum and Mitochondria

(2013) V. V. Flis et al.   Cold Spring Harbor Perspectives in Biology

HIF1α induced switch from bivalent to exclusively glycolytic metabolism during ESC-to-EpiSC/hESC transition

(2012) Wenyu Zhou et al.   EMBO JOURNAL

Phosphatidylethanolamine Deficiency in Mammalian Mitochondria Impairs Oxidative Phosphorylation and Alters Mitochondrial Morphology

(2012) Guergana Tasseva et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Influence of Threonine Metabolism on S-Adenosylmethionine and Histone Methylation

(2012) N. Shyh-Chang et al.   SCIENCE

The dynamic regulation of NAD metabolism in mitochondria

(2012) Liana Roberts Stein et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Histone Deacetylase Inhibitors in Cell Pluripotency, Differentiation, and Reprogramming

(2012) Androniki Kretsovali et al.   Stem Cells International

Somatic Oxidative Bioenergetics Transitions into Pluripotency-Dependent Glycolysis to Facilitate Nuclear Reprogramming

(2011) Clifford D.L. Folmes et al.   Cell Metabolism

Metabolic oxidation regulates embryonic stem cell differentiation

(2010) Oscar Yanes et al.   Nature Chemical Biology

PAT proteins, an ancient family of lipid droplet proteins that regulate cellular lipid stores

(2009) Perry E. Bickel et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS