Non-classical tissue monocytes and two functionally distinct populations of interstitial macrophages populate the mouse lung

Two distinct interstitial macrophage populations coexist across tissues in specific subtissular niches

(2019) Svetoslav Chakarov et al.   SCIENCE

Slingshot: cell lineage and pseudotime inference for single-cell transcriptomics

(2018) Kelly Street et al.   BMC GENOMICS

The interstitial macrophage: A long-neglected piece in the puzzle of lung immunity

(2018) Maude Liegeois et al.   CELLULAR IMMUNOLOGY

Integrating single-cell transcriptomic data across different conditions, technologies, and species

(2018) Andrew Butler et al.   NATURE BIOTECHNOLOGY

Lung Interstitial Macrophages: Past, Present, and Future

(2018) Joey Schyns et al.   Journal of Immunology Research

Self-Maintaining Gut Macrophages Are Essential for Intestinal Homeostasis

(2018) Sebastiaan De Schepper et al.   CELL

The Transcription Factor ZEB2 Is Required to Maintain the Tissue-Specific Identities of Macrophages

(2018) Charlotte L. Scott et al.   IMMUNITY

RNA velocity of single cells

(2018) Gioele La Manno et al.   NATURE

Lung Single-Cell Signaling Interaction Map Reveals Basophil Role in Macrophage Imprinting

(2018) Merav Cohen et al.   CELL

Exposure to Bacterial CpG DNA Protects from Airway Allergic Inflammation by Expanding Regulatory Lung Interstitial Macrophages

(2017) Catherine Sabatel et al.   IMMUNITY

Induced-Pluripotent-Stem-Cell-Derived Primitive Macrophages Provide a Platform for Modeling Tissue-Resident Macrophage Differentiation and Function

(2017) Kazuyuki Takata et al.   IMMUNITY

Genomic Characterization of Murine Monocytes Reveals C/EBPβ Transcription Factor Dependence of Ly6C − Cells

(2017) Alexander Mildner et al.   IMMUNITY

Human asthma is characterized by more IRF5+ M1 and CD206+ M2 macrophages and less IL-10+ M2-like macrophages around airways compared with healthy airways

(2017) Christina Draijer et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Massively parallel digital transcriptional profiling of single cells

(2017) Grace X. Y. Zheng et al.   Nature Communications

Developmental origin of lung macrophage diversity

(2016) Serena Y. S. Tan et al.   DEVELOPMENT

Yolk Sac Macrophages, Fetal Liver, and Adult Monocytes Can Colonize an Empty Niche and Develop into Functional Tissue-Resident Macrophages

(2016) Lianne van de Laar et al.   IMMUNITY

Tissue-Resident Macrophage Ontogeny and Homeostasis

(2016) Florent Ginhoux et al.   IMMUNITY

IL-10-producing lung interstitial macrophages prevent neutrophilic asthma

(2016) Hideo Kawano et al.   INTERNATIONAL IMMUNOLOGY

The microbial environment and its influence on asthma prevention in early life

(2016) Erika von Mutius   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Lung-resident eosinophils represent a distinct regulatory eosinophil subset

(2016) Claire Mesnil et al.   JOURNAL OF CLINICAL INVESTIGATION

Tissue biology perspective on macrophages

(2016) Yasutaka Okabe et al.   NATURE IMMUNOLOGY

Bone marrow-derived monocytes give rise to self-renewing and fully differentiated Kupffer cells

(2016) Charlotte L. Scott et al.   Nature Communications

Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets

(2015) Evan Z. Macosko et al.   CELL

Immune surveillance of the lung by migrating tissue monocytes

(2015) Mathieu P Rodero et al.   eLife

Tissue-Resident Macrophage Enhancer Landscapes Are Shaped by the Local Microenvironment

(2014) Yonit Lavin et al.   CELL

Origin and Functions of Tissue Macrophages

(2014) Slava Epelman et al.   IMMUNITY

Induction of the nuclear receptor PPAR-γ by the cytokine GM-CSF is critical for the differentiation of fetal monocytes into alveolar macrophages

(2014) Christoph Schneider et al.   NATURE IMMUNOLOGY

Minimal Differentiation of Classical Monocytes as They Survey Steady-State Tissues and Transport Antigen to Lymph Nodes

(2013) Claudia Jakubzick et al.   IMMUNITY

Alveolar macrophages develop from fetal monocytes that differentiate into long-lived cells in the first week of life via GM-CSF

(2013) Martin Guilliams et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Fate Mapping Reveals Origins and Dynamics of Monocytes and Tissue Macrophages under Homeostasis

(2012) Simon Yona et al.   IMMUNITY

Novel Highly Sensitive IL-10- -Lactamase Reporter Mouse Reveals Cells of the Innate Immune System as a Substantial Source of IL-10 In Vivo

(2011) H. Bouabe et al.   JOURNAL OF IMMUNOLOGY

The transcription factor NR4A1 (Nur77) controls bone marrow differentiation and the survival of Ly6C− monocytes

(2011) Richard N Hanna et al.   NATURE IMMUNOLOGY

Lung interstitial macrophages alter dendritic cell functions to prevent airway allergy in mice

(2009) Denis Bedoret et al.   JOURNAL OF CLINICAL INVESTIGATION