Lactate regulates cell cycle by remodelling the anaphase promoting complex

Molecular mechanisms of APC/C release from spindle assembly checkpoint inhibition by APC/C SUMOylation

(2021) Stanislau Yatskevich et al.   Cell Reports

Thermal proteome profiling for interrogating protein interactions

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Increased demand for NAD+ relative to ATP drives aerobic glycolysis

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Lactate Limits T Cell Proliferation via the NAD(H) Redox State

(2020) William J. Quinn et al.   Cell Reports

ZincBind—the database of zinc binding sites

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FOXK1 and FOXK2 regulate aerobic glycolysis

(2019) Valentina Sukonina et al.   NATURE

Characterization and Optimization of Multiplexed Quantitative Analyses Using High-Field Asymmetric-Waveform Ion Mobility Mass Spectrometry

(2019) Devin K. Schweppe et al.   ANALYTICAL CHEMISTRY

The landscape of cancer cell line metabolism

(2019) Haoxin Li et al.   NATURE MEDICINE

Succinate induces skeletal muscle fiber remodeling via SUNCR 1 signaling pathway

(2019) Tao Wang et al.   EMBO REPORTS

SUMO targets the APC/C to regulate transition from metaphase to anaphase

(2018) Karolin Eifler et al.   Nature Communications

Sumoylation promotes optimal APC/C activation and timely anaphase

(2018) Christine C Lee et al.   eLife

Optimal control theory enables homonuclear decoupling without Bloch–Siegert shifts in NMR spectroscopy

(2018) Paul W. Coote et al.   Nature Communications

Posing the APC/C E3 Ubiquitin Ligase to Orchestrate Cell Division

(2018) Edmond R. Watson et al.   TRENDS IN CELL BIOLOGY

Causes and Significance of Increased Compound Potency in Cellular or Physiological Contexts

(2017) Adam G. Schwaid et al.   JOURNAL OF MEDICINAL CHEMISTRY

Glucose feeds the TCA cycle via circulating lactate

(2017) Sheng Hui et al.   NATURE

A Flux Balance of Glucose Metabolism Clarifies the Requirements of the Warburg Effect

(2016) Ziwei Dai et al.   BIOPHYSICAL JOURNAL

Absolute Quantification of Matrix Metabolites Reveals the Dynamics of Mitochondrial Metabolism

(2016) Walter W. Chen et al.   CELL

Cryo-EM of Mitotic Checkpoint Complex-Bound APC/C Reveals Reciprocal and Conformational Regulation of Ubiquitin Ligation

(2016) Masaya Yamaguchi et al.   MOLECULAR CELL

Molecular basis of APC/C regulation by the spindle assembly checkpoint

(2016) Claudio Alfieri et al.   NATURE

Thermal proteome profiling: unbiased assessment of protein state through heat-induced stability changes

(2016) André Mateus et al.   Proteome Science

Atomic structure of the APC/C and its mechanism of protein ubiquitination

(2015) Leifu Chang et al.   NATURE

Thermal proteome profiling for unbiased identification of direct and indirect drug targets using multiplexed quantitative mass spectrometry

(2015) Holger Franken et al.   Nature Protocols

Spatiotemporal regulation of the anaphase-promoting complex in mitosis

(2015) Sushama Sivakumar et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

RING E3 mechanism for ubiquitin ligation to a disordered substrate visualized for human anaphase-promoting complex

(2015) Nicholas G. Brown et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CDK1 structures reveal conserved and unique features of the essential cell cycle CDK

(2015) Nicholas R. Brown et al.   Nature Communications

MultiNotch MS3 Enables Accurate, Sensitive, and Multiplexed Detection of Differential Expression across Cancer Cell Line Proteomes

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Intracellular drug concentration and disposition – The missing link?

(2014) Michael M. Hann et al.   METHODS

Tracking cancer drugs in living cells by thermal profiling of the proteome

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A Competitive Chemical-Proteomic Platform To Identify Zinc-Binding Cysteines

(2013) Nicholas J. Pace et al.   ACS Chemical Biology

Sumoylation: A Regulatory Protein Modification in Health and Disease

(2013) Annette Flotho et al.   Annual Review of Biochemistry

SENP1 and SENP2 affect spatial and temporal control of sumoylation in mitosis

(2013) Caelin Cubeñas-Potts et al.   MOLECULAR BIOLOGY OF THE CELL

The SUMO protease SENP1 is required for cohesion maintenance and mitotic arrest following spindle poison treatment

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Application of iterative soft thresholding for fast reconstruction of NMR data non-uniformly sampled with multidimensional Poisson Gap scheduling

(2012) Sven G. Hyberts et al.   JOURNAL OF BIOMOLECULAR NMR

Comet: An open-source MS/MS sequence database search tool

(2012) Jimmy K. Eng et al.   PROTEOMICS

The monocarboxylate transporter family-Structure and functional characterization

(2011) Andrew P. Halestrap   IUBMB LIFE

Molecular basis for the differential use of glucose and glutamine in cell proliferation as revealed by synchronized HeLa cells

(2011) S. L. Colombo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Tissue-Specific Atlas of Mouse Protein Phosphorylation and Expression

(2010) Edward L. Huttlin et al.   CELL

Poisson-Gap Sampling and Forward Maximum Entropy Reconstruction for Enhancing the Resolution and Sensitivity of Protein NMR Data

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To bind zinc or not to bind zinc: An examination of innovative approaches to improved metalloproteinase inhibition

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Mechanism of Ubiquitin-Chain Formation by the Human Anaphase-Promoting Complex

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