Adult hippocampal neurogenesis in Alzheimer’s disease: A roadmap to clinical relevance

CellRank for directed single-cell fate mapping

(2022) Marius Lange et al.   NATURE METHODS

The amyloid hypothesis in Alzheimer disease: new insights from new therapeutics

(2022) Eric Karran et al.   NATURE REVIEWS DRUG DISCOVERY

Adult Neural Stem Cell Regulation by Small Non-coding RNAs: Physiological Significance and Pathological Implications

(2022) Amber Penning et al.   Frontiers in Cellular Neuroscience

Characterization of the neurogenic niche in the aging dentate gyrus using iterative immunofluorescence imaging

(2022) John Darby Cole et al.   eLife

Adult Hippocampal Neurogenesis in Alzheimer’s Disease: An Overview of Human and Animal Studies with Implications for Therapeutic Perspectives Aimed at Memory Recovery

(2022) Stefano Farioli-Vecchioli et al.   NEURAL PLASTICITY

Restoration of hippocampal neural precursor function by ablation of senescent cells in the aging stem cell niche

(2022) Michael P. Fatt et al.   Stem Cell Reports

Astrogenesis in the murine dentate gyrus is a life‐long and dynamic process

(2022) Julia Schneider et al.   EMBO JOURNAL

Potential Mechanisms Underlying Resistance to Dementia in Non-Demented Individuals with Alzheimer’s Disease Neuropathology

(2022) Frédérique K. Kok et al.   JOURNAL OF ALZHEIMERS DISEASE

Altered adult neurogenesis and gliogenesis in patients with mesial temporal lobe epilepsy

(2022) Aswathy Ammothumkandy et al.   NATURE NEUROSCIENCE

Single-cell transcriptomics of adult macaque hippocampus reveals neural precursor cell populations

(2022) Zhao-Zhe Hao et al.   NATURE NEUROSCIENCE

Hypothalamic modulation of adult hippocampal neurogenesis in mice confers activity-dependent regulation of memory and anxiety-like behavior

(2022) Ya-Dong Li et al.   NATURE NEUROSCIENCE

Failure of Alzheimer’s Mice Brain Resident Neural Precursor Cells in Supporting Microglia-Mediated Amyloid β Clearance

(2022) Marva Lachish et al.   Cells

Lipid accumulation induced by APOE4 impairs microglial surveillance of neuronal-network activity

(2022) Matheus B. Victor et al.   Cell Stem Cell

Microglia‐dependent remodeling of neuronal circuits

(2022) Joana R. Guedes et al.   JOURNAL OF NEUROCHEMISTRY

Molecular landscapes of human hippocampal immature neurons across lifespan

(2022) Yi Zhou et al.   NATURE

Imaging and spectroscopic methods to investigate adult neurogenesis in vivo: New models and new avenues

(2022) Nathalie Just et al.   Frontiers in Neuroscience

Soluble factors influencing the neural stem cell niche in brain physiology, inflammation, and aging

(2022) Cory M. Willis et al.   EXPERIMENTAL NEUROLOGY

Methods to study adult hippocampal neurogenesis in humans and across the phylogeny

(2022) Julia Terreros‐Roncal et al.   HIPPOCAMPUS

Augmenting neurogenesis rescues memory impairments in Alzheimer’s disease by restoring the memory-storing neurons

(2022) Rachana Mishra et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Multi-omic single-cell velocity models epigenome–transcriptome interactions and improves cell fate prediction

(2022) Chen Li et al.   NATURE BIOTECHNOLOGY

Adult-born dentate granule cells promote hippocampal population sparsity

(2022) Stephen B. McHugh et al.   NATURE NEUROSCIENCE

Microglia states and nomenclature: A field at its crossroads

(2022) Rosa C. Paolicelli et al.   NEURON

Progression of Alzheimer's disease parallels unusual structural plasticity of human dentate granule cells

(2022) B. Márquez-Valadez et al.   Acta Neuropathologica Communications

Increased post-mitotic senescence in aged human neurons is a pathological feature of Alzheimer’s disease

(2022) Joseph R. Herdy et al.   Cell Stem Cell

A single-cell transcriptome atlas of glial diversity in the human hippocampus across the postnatal lifespan

(2022) Yijing Su et al.   Cell Stem Cell

Familial Alzheimer’s Disease Mutations in PSEN1 Lead to Premature Human Stem Cell Neurogenesis

(2021) Charles Arber et al.   Cell Reports

Coordinated changes in cellular behavior ensure the lifelong maintenance of the hippocampal stem cell population

(2021) Lachlan Harris et al.   Cell Stem Cell

Formation and integration of new neurons in the adult hippocampus

(2021) Annina Denoth-Lippuner et al.   NATURE REVIEWS NEUROSCIENCE

Early stem cell aging in the mature brain

(2021) Albina Ibrayeva et al.   Cell Stem Cell

Age-dependent instability of mature neuronal fate in induced neurons from Alzheimer’s patients

(2021) Jerome Mertens et al.   Cell Stem Cell

Positive Controls in Adults and Children Support That Very Few, If Any, New Neurons Are Born in the Adult Human Hippocampus

(2021) Shawn F. Sorrells et al.   JOURNAL OF NEUROSCIENCE

IL4-driven microglia modulate stress resilience through BDNF-dependent neurogenesis

(2021) Jinqiang Zhang et al.   Science Advances

The serum metabolome mediates the concert of diet, exercise, and neurogenesis, determining the risk for cognitive decline and dementia

(2021) Andrea Du Preez et al.   Alzheimers & Dementia

Single-nucleus chromatin accessibility and transcriptomic characterization of Alzheimer’s disease

(2021) Samuel Morabito et al.   NATURE GENETICS

Resolving cellular and molecular diversity along the hippocampal anterior-to-posterior axis in humans

(2021) Fatma Ayhan et al.   NEURON

The interplay of neurovasculature and adult hippocampal neurogenesis

(2021) Thomas A. Kim et al.   NEUROSCIENCE LETTERS

The neurogenic niche in Alzheimer’s disease

(2021) Connor M. Wander et al.   NEUROSCIENCE LETTERS

Cellular senescence at the crossroads of inflammation and Alzheimer's disease

(2021) Ana Guerrero et al.   TRENDS IN NEUROSCIENCES

Single-nucleus transcriptomic landscape of primate hippocampal aging

(2021) Hui Zhang et al.   Protein & Cell

Targeting impaired adult hippocampal neurogenesis in ageing by leveraging intrinsic mechanisms regulating Neural Stem Cell activity

(2021) Sébastien Gillotin et al.   AGEING RESEARCH REVIEWS

Restoring miR-132 expression rescues adult hippocampal neurogenesis and memory deficits in Alzheimer’s disease

(2021) Hannah Walgrave et al.   Cell Stem Cell

What have we learned from past failures of investigational drugs for Alzheimer’s disease?

(2021) Bruno P. Imbimbo et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

A multimodal cell census and atlas of the mammalian primary motor cortex

(2021) et al.   NATURE

Transcriptomic taxonomy and neurogenic trajectories of adult human, macaque, and pig hippocampal and entorhinal cells

(2021) Daniel Franjic et al.   NEURON

Epigenetic regulation in the neurogenic niche of the adult dentate gyrus

(2021) Ryan N. Sheehy et al.   NEUROSCIENCE LETTERS

Impact of neurodegenerative diseases on human adult hippocampal neurogenesis

(2021) J. Terreros-Roncal et al.   SCIENCE

Modulating adult neurogenesis affects synaptic plasticity and cognitive functions in mouse models of Alzheimer's disease

(2021) Xiaoqin Zhang et al.   Stem Cell Reports

Neurogenic-dependent changes in hippocampal circuitry underlie the procognitive effect of exercise in aging mice

(2021) Xiaoqing Alice Zhou et al.   iScience

Microglia Actively Remodel Adult Hippocampal Neurogenesis through the Phagocytosis Secretome

(2020) Irune Diaz-Aparicio et al.   JOURNAL OF NEUROSCIENCE

Unraveling human adult hippocampal neurogenesis

(2020) Miguel Flor-García et al.   Nature Protocols

Communication, Cross Talk, and Signal Integration in the Adult Hippocampal Neurogenic Niche

(2020) Cinzia Vicidomini et al.   NEURON

Interneuron Accumulation of Phosphorylated tau Impairs Adult Hippocampal Neurogenesis by Suppressing GABAergic Transmission

(2020) Jie Zheng et al.   Cell Stem Cell

Single-cell-resolution transcriptome map of human, chimpanzee, bonobo, and macaque brains

(2020) Ekaterina Khrameeva et al.   GENOME RESEARCH

Lineage tracing meets single-cell omics: opportunities and challenges

(2020) Daniel E. Wagner et al.   NATURE REVIEWS GENETICS

Mechanisms of enhanced quiescence in neural stem cell aging

(2020) Amanda J Audesse et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Deciphering cellular transcriptional alterations in Alzheimer’s disease brains

(2020) Xue Wang et al.   Molecular Neurodegeneration

Hippocampal neural stem cells facilitate access from circulation via apical cytoplasmic processes

(2020) Tamar Licht et al.   eLife

Genetic variants and functional pathways associated with resilience to Alzheimer’s disease

(2020) Logan Dumitrescu et al.   BRAIN

Neuropeptides Modulate Local Astrocytes to Regulate Adult Hippocampal Neural Stem Cells

(2020) Brent Asrican et al.   NEURON

Single cell RNA sequencing of human microglia uncovers a subset associated with Alzheimer’s disease

(2020) Marta Olah et al.   Nature Communications

Ablating Adult Neural Stem Cells Improves Synaptic and Cognitive Functions in Alzheimer Models

(2020) Xiaoqin Zhang et al.   Stem Cell Reports

Adult hippocampal neurogenesis is abundant in neurologically healthy subjects and drops sharply in patients with Alzheimer’s disease

(2019) Elena P. Moreno-Jiménez et al.   NATURE MEDICINE

Quiescence Modulates Stem Cell Maintenance and Regenerative Capacity in the Aging Brain

(2019) Georgios Kalamakis et al.   CELL

Human Hippocampal Neurogenesis Persists in Aged Adults and Alzheimer’s Disease Patients

(2019) Matthew K. Tobin et al.   Cell Stem Cell

Adult-born hippocampal neurons bidirectionally modulate entorhinal inputs into the dentate gyrus

(2019) Victor M. Luna et al.   SCIENCE

Deficits in Enrichment-Dependent neurogenesis and enhanced Anxiety behaviors mediated by expression of Alzheimer's disease-linked PS1 variants are rescued by Microglial Depletion

(2019) Sylvia Ortega-Martinez et al.   JOURNAL OF NEUROSCIENCE

Circadian glucocorticoid oscillations preserve a population of adult hippocampal neural stem cells in the aging brain

(2019) M. Schouten et al.   MOLECULAR PSYCHIATRY

Single-cell analysis reveals T cell infiltration in old neurogenic niches

(2019) Ben W. Dulken et al.   NATURE

Neurovascular Coupling in the Dentate Gyrus Regulates Adult Hippocampal Neurogenesis

(2019) Jia Shen et al.   NEURON

Functions of adult-born neurons in hippocampal memory interference and indexing

(2019) Samara M. Miller et al.   NATURE NEUROSCIENCE

High-resolution mapping of brain vasculature and its impairment in the hippocampus of Alzheimer's disease mice

(2019) Xiaochuan Zhang et al.   National Science Review

Cellular Senescence: Defining a Path Forward

(2019) Vassilis Gorgoulis et al.   CELL

Adult neurogenesis, human after all (again): Classic, optimized, and future approaches

(2019) Paul J. Lucassen et al.   BEHAVIOURAL BRAIN RESEARCH

Brain Endothelial Cells Maintain Lactate Homeostasis and Control Adult Hippocampal Neurogenesis

(2019) Jun Wang et al.   Cell Stem Cell

Quiescence of Adult Mammalian Neural Stem Cells: A Highly Regulated Rest

(2019) Noelia Urbán et al.   NEURON

Disease-Associated Microglia: A Universal Immune Sensor of Neurodegeneration

(2018) Aleksandra Deczkowska et al.   CELL

Single-Cell Transcriptomics Meets Lineage Tracing

(2018) Lennart Kester et al.   Cell Stem Cell

Human Hippocampal Neurogenesis Persists throughout Aging

(2018) Maura Boldrini et al.   Cell Stem Cell

Human Adult Neurogenesis: Evidence and Remaining Questions

(2018) Gerd Kempermann et al.   Cell Stem Cell

Hippocampal Radial Glial Subtypes and Their Neurogenic Potential in Human Fetuses and Healthy and Alzheimer’s Disease Adults

(2018) Sara Cipriani et al.   CEREBRAL CORTEX

Increased Microglial Activity, Impaired Adult Hippocampal Neurogenesis, and Depressive-like Behavior in Microglial VPS35-Depleted Mice

(2018) Joanna Ruth Appel et al.   JOURNAL OF NEUROSCIENCE

Human hippocampal neurogenesis drops sharply in children to undetectable levels in adults

(2018) Shawn F. Sorrells et al.   NATURE

Conserved properties of dentate gyrus neurogenesis across postnatal development revealed by single-cell RNA sequencing

(2018) Hannah Hochgerner et al.   NATURE NEUROSCIENCE

Precision pharmacology for Alzheimer’s disease

(2018) Harald Hampel et al.   PHARMACOLOGICAL RESEARCH

The effects of death and post-mortem cold ischemia on human tissue transcriptomes

(2018) Pedro G. Ferreira et al.   Nature Communications

Adult Hippocampal Neurogenesis: Regulation and Possible Functional and Clinical Correlates

(2018) Pedro Baptista et al.   Frontiers in Neuroanatomy

Impaired Hippocampal Neurogenesis and its Enhancement with Ghrelin in 5XFAD Mice

(2018) Minho Moon et al.   JOURNAL OF ALZHEIMERS DISEASE

RNA velocity of single cells

(2018) Gioele La Manno et al.   NATURE

Resident brain neural precursor cells develop age-dependent loss of therapeutic functions in Alzheimer's mice

(2018) Nina Fainstein et al.   NEUROBIOLOGY OF AGING

Mossy Cells Control Adult Neural Stem Cell Quiescence and Maintenance through a Dynamic Balance between Direct and Indirect Pathways

(2018) Chia-Yu Yeh et al.   NEURON

Combined adult neurogenesis and BDNF mimic exercise effects on cognition in an Alzheimer’s mouse model

(2018) Se Hoon Choi et al.   SCIENCE

Does Adult Neurogenesis Persist in the Human Hippocampus?

(2018) Mercedes F. Paredes et al.   Cell Stem Cell

Unique role for dentate gyrus microglia in neuroblast survival and in VEGF-induced activation

(2018) Tirzah Kreisel et al.   GLIA

Depletion of adult neurogenesis exacerbates cognitive deficits in Alzheimer’s disease by compromising hippocampal inhibition

(2017) Carolyn Hollands et al.   Molecular Neurodegeneration

Role of Mitochondrial Metabolism in the Control of Early Lineage Progression and Aging Phenotypes in Adult Hippocampal Neurogenesis

(2017) Ruth Beckervordersandforth et al.   NEURON

Neurons derived from sporadic Alzheimer’s disease iPSCs reveal elevated TAU hyperphosphorylation, increased amyloid levels, and GSK3B activation

(2017) Anna Ochalek et al.   Alzheimers Research & Therapy

Coupled Proliferation and Apoptosis Maintain the Rapid Turnover of Microglia in the Adult Brain

(2017) Katharine Askew et al.   Cell Reports

A Single-Cell RNA Sequencing Study Reveals Cellular and Molecular Dynamics of the Hippocampal Neurogenic Niche

(2017) Benedetta Artegiani et al.   Cell Reports

Tracing the dynamics of gene transcripts after organismal death

(2017) Alex E. Pozhitkov et al.   Open Biology

Running reorganizes the circuitry of one-week-old adult-born hippocampal neurons

(2017) Nirnath Sah et al.   Scientific Reports

Soluble phospho-tau from Alzheimer’s disease hippocampus drives microglial degeneration

(2016) Elisabeth Sanchez-Mejias et al.   ACTA NEUROPATHOLOGICA

Hippocampal bone morphogenetic protein signaling mediates behavioral effects of antidepressant treatment

(2016) S M Brooker et al.   MOLECULAR PSYCHIATRY

Modulating Neuronal Competition Dynamics in the Dentate Gyrus to Rejuvenate Aging Memory Circuits

(2016) Kathleen M. McAvoy et al.   NEURON

Human adult neurogenesis across the ages: An immunohistochemical study

(2016) C. V. Dennis et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Div-Seq: Single-nucleus RNA-Seq reveals dynamics of rare adult newborn neurons

(2016) Naomi Habib et al.   SCIENCE

Brain Insulin-Like Growth Factor-I Directs the Transition from Stem Cells to Mature Neurons During Postnatal/Adult Hippocampal Neurogenesis

(2016) Vanesa Nieto-Estévez et al.   STEM CELLS

Preserved neurogenesis in non-demented individuals with AD neuropathology

(2016) David Briley et al.   Scientific Reports

Neuronal Hyperactivity Accelerates Depletion of Neural Stem Cells and Impairs Hippocampal Neurogenesis

(2015) Amanda Sierra et al.   Cell Stem Cell

Single-Cell RNA-Seq with Waterfall Reveals Molecular Cascades underlying Adult Neurogenesis

(2015) Jaehoon Shin et al.   Cell Stem Cell

Voluntary exercise attenuates LPS-induced reductions in neurogenesis and increases microglia expression of a proneurogenic phenotype in aged mice

(2015) Alyssa M. Littlefield et al.   Journal of Neuroinflammation

Synaptic Integration of Adult-Born Hippocampal Neurons Is Locally Controlled by Astrocytes

(2015) Sébastien Sultan et al.   NEURON

Structural imaging of hippocampal subfields in healthy aging and Alzheimer’s disease

(2015) Robin de Flores et al.   NEUROSCIENCE

Brain region-specific gene expression profiles in freshly isolated rat microglia

(2015) Karlijn J. Doorn et al.   Frontiers in Cellular Neuroscience

Vascular Endothelial Growth Factor Receptor 3 Controls Neural Stem Cell Activation in Mice and Humans

(2015) Jinah Han et al.   Cell Reports

Genetic manipulation of adult-born hippocampal neurons rescues memory in a mouse model of Alzheimer’s disease

(2014) Kevin Richetin et al.   BRAIN

Chitosan in nasal delivery systems for therapeutic drugs

(2014) Luca Casettari et al.   JOURNAL OF CONTROLLED RELEASE

Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice

(2014) Saul A Villeda et al.   NATURE MEDICINE

Hippocampal Neurogenesis Regulates Forgetting During Adulthood and Infancy

(2014) K. G. Akers et al.   SCIENCE

Microglia from neurogenic and non-neurogenic regions display differential proliferative potential and neuroblast support

(2014) Gregory P. Marshall et al.   Frontiers in Cellular Neuroscience

Performance on a pattern separation task by Alzheimer’s patients shows possible links between disrupted dentate gyrus activity and apolipoprotein E ∈4 status and cerebrospinal fluid amyloid-β42 levels

(2014) Keith A Wesnes et al.   Alzheimers Research & Therapy

Dynamics of Hippocampal Neurogenesis in Adult Humans

(2013) Kirsty L. Spalding et al.   CELL

Secreted Frizzled-Related Protein 3 Regulates Activity-Dependent Adult Hippocampal Neurogenesis

(2013) Mi-Hyeon Jang et al.   Cell Stem Cell

Pattern separation and pattern completion in Alzheimer's disease: Evidence of rapid forgetting in amnestic mild cognitive impairment

(2013) Brandon A. Ally et al.   HIPPOCAMPUS

Physical Exercise Prevents Stress-Induced Activation of Granule Neurons and Enhances Local Inhibitory Mechanisms in the Dentate Gyrus

(2013) T. J. Schoenfeld et al.   JOURNAL OF NEUROSCIENCE

Parvalbumin interneurons mediate neuronal circuitry–neurogenesis coupling in the adult hippocampus

(2013) Juan Song et al.   NATURE NEUROSCIENCE

Soluble amyloid precursor protein-α rescues age-linked decline in neural progenitor cell proliferation

(2013) Michael P. Demars et al.   NEUROBIOLOGY OF AGING

Inhibitory Neuron and Hippocampal Circuit Dysfunction in an Aged Mouse Model of Alzheimer's Disease

(2013) Anupam Hazra et al.   PLoS One

BDNF overexpression in mouse hippocampal astrocytes promotes local neurogenesis and elicits anxiolytic-like activities

(2013) G Quesseveur et al.   Translational Psychiatry

Synaptic Distributions of GluA2 and PKM  in the Monkey Dentate Gyrus and Their Relationships with Aging and Memory

(2012) Y. Hara et al.   JOURNAL OF NEUROSCIENCE

Microglia Modulate Hippocampal Neural Precursor Activity in Response to Exercise and Aging

(2012) J. Vukovic et al.   JOURNAL OF NEUROSCIENCE

Cell Cycle Activation and Aneuploid Neurons in Alzheimer's Disease

(2012) Thomas Arendt   MOLECULAR NEUROBIOLOGY

Knockdown of the glucocorticoid receptor alters functional integration of newborn neurons in the adult hippocampus and impairs fear-motivated behavior

(2012) C P Fitzsimons et al.   MOLECULAR PSYCHIATRY

Neuronal circuitry mechanism regulating adult quiescent neural stem-cell fate decision

(2012) Juan Song et al.   NATURE

Neural progenitor cells regulate microglia functions and activity

(2012) Kira I Mosher et al.   NATURE NEUROSCIENCE

CCL2 affects β-amyloidosis and progressive neurocognitive dysfunction in a mouse model of Alzheimer's disease

(2012) Tomomi Kiyota et al.   NEUROBIOLOGY OF AGING

Inhibition of Microglial Activation Protects Hippocampal Neurogenesis and Improves Cognitive Deficits in a Transgenic Mouse Model for Alzheimer’s Disease

(2012) Barbara Biscaro et al.   Neurodegenerative Diseases

Unique Processing During a Period of High Excitation/Inhibition Balance in Adult-Born Neurons

(2012) Antonia Marín-Burgin et al.   SCIENCE

Astrocytes Negatively Regulate Neurogenesis Through the Jagged1-Mediated Notch Pathway

(2012) Ulrika Wilhelmsson et al.   STEM CELLS

Wheel running attenuates microglia proliferation and increases expression of a proneurogenic phenotype in the hippocampus of aged mice

(2011) Rachel A. Kohman et al.   BRAIN BEHAVIOR AND IMMUNITY

Adult hippocampal neurogenesis and its role in Alzheimer's disease

(2011) Yangling Mu et al.   Molecular Neurodegeneration

The ageing systemic milieu negatively regulates neurogenesis and cognitive function

(2011) Saul A. Villeda et al.   NATURE

Age-related memory deficits linked to circuit-specific disruptions in the hippocampus

(2011) M. A. Yassa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reversible modulations of neuronal plasticity by VEGF

(2011) T. Licht et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Low proliferation and differentiation capacities of adult hippocampal stem cells correlate with memory dysfunction in humans

(2010) R. Coras et al.   BRAIN

Microglia Shape Adult Hippocampal Neurogenesis through Apoptosis-Coupled Phagocytosis

(2010) Amanda Sierra et al.   Cell Stem Cell

Neurogenesis and Alzheimers Disease: Biology and Pathophysiology in Mice and Men

(2010) M. Marlatt et al.   Current Alzheimer Research

Effects of neuroinflammation on the regenerative capacity of brain stem cells

(2010) Isabella Russo et al.   JOURNAL OF NEUROCHEMISTRY

Impaired neurogenesis is an early event in the etiology of familial Alzheimer's disease in transgenic mice

(2010) Michael Demars et al.   JOURNAL OF NEUROSCIENCE RESEARCH

High-resolution structural and functional MRI of hippocampal CA3 and dentate gyrus in patients with amnestic Mild Cognitive Impairment

(2010) Michael A. Yassa et al.   NEUROIMAGE

Murine Features of Neurogenesis in the Human Hippocampus across the Lifespan from 0 to 100 Years

(2010) Rolf Knoth et al.   PLoS One

GABAergic Interneuron Dysfunction Impairs Hippocampal Neurogenesis in Adult Apolipoprotein E4 Knockin Mice

(2009) Gang Li et al.   Cell Stem Cell

Neural Stem and Progenitor Cells Retain Their Potential for Proliferation and Differentiation into Functional Neurons Despite Lower Number in Aged Brain

(2009) H. Ahlenius et al.   JOURNAL OF NEUROSCIENCE

Fractalkine and CX3CR1 regulate hippocampal neurogenesis in adult and aged rats

(2009) Adam D. Bachstetter et al.   NEUROBIOLOGY OF AGING

Neuronal Activity-Induced Gadd45b Promotes Epigenetic DNA Demethylation and Adult Neurogenesis

(2009) D. K. Ma et al.   SCIENCE

Stem Cells and Niches: Mechanisms That Promote Stem Cell Maintenance throughout Life

(2008) Sean J. Morrison et al.   CELL

Non-Cell-Autonomous Effects of Presenilin 1 Variants on Enrichment-Mediated Hippocampal Progenitor Cell Proliferation and Differentiation

(2008) Se Hoon Choi et al.   NEURON

Impaired Adult Neurogenesis in the Dentate Gyrus of a Triple Transgenic Mouse Model of Alzheimer's Disease

(2008) José J. Rodríguez et al.   PLoS One