Depletion of adult neurogenesis exacerbates cognitive deficits in Alzheimer’s disease by compromising hippocampal inhibition

Hippocampal neurogenesis: Learning to remember

(2016) Orly Lazarov et al.   PROGRESS IN NEUROBIOLOGY

Amyloid β Is Not the Major Factor Accounting for Impaired Adult Hippocampal Neurogenesis in Mice Overexpressing Amyloid Precursor Protein

(2016) Hongyu Pan et al.   Stem Cell Reports

Human neural stem cells improve cognition and promote synaptic growth in two complementary transgenic models of Alzheimer's disease and neuronal loss

(2015) Rahasson R. Ager et al.   HIPPOCAMPUS

Presenilin-1 Dependent Neurogenesis Regulates Hippocampal Learning and Memory

(2015) Jacqueline A. Bonds et al.   PLoS One

CA3 Retrieves Coherent Representations from Degraded Input: Direct Evidence for CA3 Pattern Completion and Dentate Gyrus Pattern Separation

(2014) Joshua P. Neunuebel et al.   NEURON

Soluble amyloid precursor protein-α rescues age-linked decline in neural progenitor cell proliferation

(2013) Michael P. Demars et al.   NEUROBIOLOGY OF AGING

Molecular Mechanism for Age-Related Memory Loss: The Histone-Binding Protein RbAp48

(2013) E. Pavlopoulos et al.   Science Translational Medicine

Adult neurogenesis modifies excitability of the dentate gyrus

(2013) Taruna Ikrar et al.   Frontiers in Neural Circuits

Of mice and men: neurogenesis, cognition and Alzheimer’s disease

(2013) Orly Lazarov et al.   Frontiers in Aging Neuroscience

Ablating Adult Neurogenesis in the Rat Has No Effect on Spatial Processing: Evidence from a Novel Pharmacogenetic Model

(2013) James O. Groves et al.   PLoS Genetics

NR2B-Dependent Plasticity of Adult-Born Granule Cells is Necessary for Context Discrimination

(2012) M. A. Kheirbek et al.   JOURNAL OF NEUROSCIENCE

Suppression of adult neurogenesis impairs population coding of similar contexts in hippocampal CA3 region

(2012) Yosuke Niibori et al.   Nature Communications

Secreted amyloid precursor proteins promote proliferation and glial differentiation of adult hippocampal neural progenitor cells

(2011) Sara Baratchi et al.   HIPPOCAMPUS

Presenilin-1 Regulates Neural Progenitor Cell Differentiation in the Adult Brain

(2011) A. Gadadhar et al.   JOURNAL OF NEUROSCIENCE

Increasing adult hippocampal neurogenesis is sufficient to improve pattern separation

(2011) Amar Sahay et al.   NATURE

Pattern Separation: A Common Function for New Neurons in Hippocampus and Olfactory Bulb

(2011) Amar Sahay et al.   NEURON

Soluble amyloid precursor protein: a novel proliferation factor of adult progenitor cells of ectodermal and mesodermal origin

(2011) Michael P Demars et al.   Stem Cell Research & Therapy

Widespread deficits in adult neurogenesis precede plaque and tangle formation in the 3xTg mouse model of Alzheimer’s disease

(2010) Laura K. Hamilton et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Complex environment experience rescues impaired neurogenesis, enhances synaptic plasticity, and attenuates neuropathology in familial Alzheimer’s disease-linked APPswe/PS1ΔE9 mice

(2010) Yuan-Shih Hu et al.   FASEB JOURNAL

Adult-born neurons are necessary for extended contextual discrimination

(2010) Sophie Tronel et al.   HIPPOCAMPUS

Impaired neurogenesis is an early event in the etiology of familial Alzheimer's disease in transgenic mice

(2010) Michael Demars et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Individual differences in spatial pattern separation performance associated with healthy aging in humans

(2010) S. M. Stark et al.   LEARNING & MEMORY

When neurogenesis encounters aging and disease

(2010) Orly Lazarov et al.   TRENDS IN NEUROSCIENCES

Neurogenesis and Alzheimer's disease: At the crossroads

(2009) Orly Lazarov et al.   EXPERIMENTAL NEUROLOGY

Visual object pattern separation deficits in nondemented older adults

(2009) C. K. Toner et al.   LEARNING & MEMORY

Inhibitors of Class 1 Histone Deacetylases Reverse Contextual Memory Deficits in a Mouse Model of Alzheimer's Disease

(2009) Mark Kilgore et al.   NEUROPSYCHOPHARMACOLOGY

Traumatic Brain Injury-Induced Hippocampal Neurogenesis Requires Activation of Early Nestin-Expressing Progenitors

(2008) T.-S. Yu et al.   JOURNAL OF NEUROSCIENCE

Roles of continuous neurogenesis in the structural and functional integrity of the adult forebrain

(2008) Itaru Imayoshi et al.   NATURE NEUROSCIENCE

Impaired Adult Neurogenesis in the Dentate Gyrus of a Triple Transgenic Mouse Model of Alzheimer's Disease

(2008) José J. Rodríguez et al.   PLoS One