Klebsiella pneumoniae Carbapenemase Variants Resistant to Ceftazidime-Avibactam: an Evolutionary Overview
出版年份 2022 全文链接
标题
Klebsiella pneumoniae Carbapenemase Variants Resistant to Ceftazidime-Avibactam: an Evolutionary Overview
作者
关键词
-
出版物
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Volume 66, Issue 9, Pages -
出版商
American Society for Microbiology
发表日期
2022-08-18
DOI
10.1128/aac.00447-22
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- In vivo selection of KPC-94 and KPC-95 in Klebsiella pneumoniae isolates from patients treated with ceftazidime/avibactam
- (2022) J. Guzmán-Puche et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- Structural Characterization of the D179N and D179Y Variants of KPC-2 β-Lactamase: Ω-Loop Destabilization as a Mechanism of Resistance to Ceftazidime-Avibactam
- (2022) T. A. Alsenani et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Different Conformations Revealed by NMR Underlie Resistance to Ceftazidime/Avibactam and Susceptibility to Meropenem and Imipenem among D179Y Variants of KPC β-Lactamase
- (2022) Magdalena A. Taracila et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Identification of a Novel Ceftazidime-Avibactam-Resistant KPC-2 Variant, KPC-123, in Citrobacter koseri Following Ceftazidime-Avibactam Treatment
- (2022) Lin Wang et al. Frontiers in Microbiology
- Continuous Evolution: Perspective on the Epidemiology of Carbapenemase Resistance Among Enterobacterales and Other Gram-Negative Bacteria
- (2021) Glen T. Hansen Infectious Diseases and Therapy
- Characterization of KPC-82, a KPC-2 variant conferring resistance to ceftazidime-avibactam in a carbapenem non-susceptible, clinical isolate of Citrobacter koseri
- (2021) Francois Lebreton et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Epidemiology of Carbapenem Resistance Determinants Identified in Meropenem-nonsusceptible Enterobacterales collected as part of a Global Surveillance Program, 2012-2017
- (2021) Krystyna M. Kazmierczak et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Cross-resistance to cefiderocol and ceftazidime–avibactam in KPC β-lactamase mutants and the inoculum effect
- (2021) Claire Amaris Hobson et al. CLINICAL MICROBIOLOGY AND INFECTION
- Molecular analysis of clinical isolates of ceftazidime-avibactam-resistant Klebsiella pneumoniae
- (2021) Carolina Venditti et al. CLINICAL MICROBIOLOGY AND INFECTION
- Designing better enzymes: Insights from directed evolution
- (2021) H. Adrian Bunzel et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Local Interactions with the Glu166 Base and the Conformation of an Active Site Loop Play Key Roles in Carbapenem Hydrolysis by the KPC-2 β-lactamase
- (2021) Ian M. Furey et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Allosteric communication in class A β-lactamases occurs via cooperative coupling of loop dynamics
- (2021) Ioannis Galdadas et al. eLife
- Evolutionary Trajectories toward Ceftazidime-Avibactam Resistance in Klebsiella pneumoniae Clinical Isolates
- (2021) Alessandra Carattoli et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- In vitro activity of cefiderocol against ceftazidime-avibactam susceptible and resistant KPC-producing Enterobacterales: cross-resistance and synergistic effects
- (2021) Gabriele Bianco et al. EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
- A genomic surveillance framework and genotyping tool for Klebsiella pneumoniae and its related species complex
- (2021) Margaret M. C. Lam et al. Nature Communications
- Resistance to ceftazidime/avibactam in infections and colonisations by KPC-producing Enterobacterales: a systematic review of observational clinical studies
- (2021) Stefano Di Bella et al. Journal of Global Antimicrobial Resistance
- KPC-39-Mediated Resistance to Ceftazidime-Avibactam in a Klebsiella pneumoniae ST307 Clinical Isolate
- (2021) Agnès B. Jousset et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Potency of Vaborbactam is Less Affected than Avibactam in Strains Producing KPC-2 Mutations that Confer Resistance to Ceftazidime-Avibactam
- (2020) Ruslan Tsivkovski et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Epidemiology of β-Lactamase-Producing Pathogens
- (2020) Karen Bush et al. CLINICAL MICROBIOLOGY REVIEWS
- KPC-50 confers resistance to ceftazidime-avibactam associated with reduced carbapenemase activity
- (2020) Laurent Poirel et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Phenotypic and genotypic analysis of KPC-51 and KPC-52, two novel KPC-2 variants conferring resistance to ceftazidime/avibactam in the KPC-producing Klebsiella pneumoniae ST11 clone background
- (2020) Lingxiao Sun et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- KPC beta-lactamases are permissive to insertions and deletions conferring substrate spectrum modifications and resistance to ceftazidime-avibactam
- (2020) Claire Amaris Hobson et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Variations in the Occurrence of Resistance Phenotypes and Carbapenemase Genes Among Enterobacteriaceae Isolates in 20 Years of the SENTRY Antimicrobial Surveillance Program
- (2019) Mariana Castanheira et al. Open Forum Infectious Diseases
- Interplay between β-lactamases and new β-lactamase inhibitors
- (2019) Karen Bush et al. NATURE REVIEWS MICROBIOLOGY
- Ceftazidime/avibactam resistance associated with L169P mutation in the omega loop of KPC-2
- (2019) Peera Hemarajata et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Emergence of ceftazidime-avibactam-resistant Klebsiella pneumoniae during treatment, Finland, December 2018
- (2019) Kati Räisänen et al. Eurosurveillance
- KPC-31 expressed in a ceftazidime/avibactam-resistant Klebsiella pneumoniae is associated with relevant detection issues
- (2019) Alberto Antonelli et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Identification of L169P mutation in the omega loop of KPC-3 after a short course of ceftazidime/avibactam
- (2019) Carolina Venditti et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Unravelling ceftazidime/avibactam resistance of KPC-28, a KPC-2 variant lacking carbapenemase activity
- (2019) Saoussen Oueslati et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- β-Lactamases and β-Lactamase Inhibitors in the 21st Century
- (2019) Catherine L. Tooke et al. JOURNAL OF MOLECULAR BIOLOGY
- Patient-to-patient transmission of KPC variants with reduced ceftazidime-avibactam susceptibility
- (2019) L. Silvia Munoz-Price et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Repeated Detection of Carbapenemase-Producing Escherichia coli in Gulls Inhabiting Alaska
- (2019) Christina A. Ahlstrom et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Emergence of ceftazidime/avibactam resistance in KPC-3-producing Klebsiella pneumoniae in vivo
- (2019) Stephan Göttig et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Epidemic of carbapenem-resistant Klebsiella pneumoniae in Europe is driven by nosocomial spread
- (2019) Sophia David et al. Nature Microbiology
- Phenotypic, biochemical and genetic analysis of KPC-41, a KPC-3 variant conferring resistance to ceftazidime-avibactam and exhibiting reduced carbapenemase activity
- (2019) Linda Mueller et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Epidemiology and Diagnostics of Carbapenem Resistance in Gram-negative Bacteria
- (2019) Patrice Nordmann et al. CLINICAL INFECTIOUS DISEASES
- Use of carbapenems in the combined treatment of emerging ceftazidime/avibactam-resistant and carbapenem-susceptible KPC-producing Klebsiella pneumoniae infections: report of a case and review of the literature
- (2019) Ángela Cano et al. Journal of Global Antimicrobial Resistance
- Different phenotypic expression of KPC β-lactamase variants and challenges in their detection
- (2019) Saoussen Oueslati et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Resistance to Ceftazidime-Avibactam and Underlying Mechanisms
- (2019) Yuhang Wang et al. Journal of Global Antimicrobial Resistance
- Pneumonia and Renal Replacement Therapy Are Risk Factors for Ceftazidime-Avibactam Treatment Failures and Resistance among Patients with Carbapenem-Resistant Enterobacteriaceae Infections
- (2018) Ryan K. Shields et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Ceftazidime/avibactam, Meropenem/vaborbactam or both? Clinical and formulary considerations
- (2018) Jason M Pogue et al. CLINICAL INFECTIOUS DISEASES
- Efficacy of Ceftazidime-avibactam Salvage Therapy in Patients with Infections Caused by KPC-producing Klebsiella pneumoniae
- (2018) Mario Tumbarello et al. CLINICAL INFECTIOUS DISEASES
- Carbapenem-resistant Enterobacteriaceae in wildlife, food-producing, and companion animals: a systematic review
- (2018) R. Köck et al. CLINICAL MICROBIOLOGY AND INFECTION
- An update on β-lactamase inhibitor discovery and development
- (2018) Jean-Denis Docquier et al. DRUG RESISTANCE UPDATES
- In vivo evolution of resistant subpopulations of KPC-producing Klebsiella pneumoniae during ceftazidime/avibactam treatment
- (2018) Paolo Gaibani et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Meropenem/Vaborbactam: A Review in Complicated Urinary Tract Infections
- (2018) Sohita Dhillon DRUGS
- Epidemiology and resistance phenotypes of carbapenemase-producing Klebsiella pneumoniae in Greece, 2014 to 2016
- (2018) Irene Galani et al. Eurosurveillance
- Defining the architecture of KPC-2 Carbapenemase: identifying allosteric networks to fight antibiotics resistance
- (2018) Ioannis Galdadas et al. Scientific Reports
- Loop Motion in Triosephosphate Isomerase Is Not a Simple Open and Shut Case
- (2018) Qinghua Liao et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Characterization of extended-spectrum β-lactamases (ESBLs)-producing Salmonella in retail raw chicken carcasses
- (2017) Jing Qiao et al. INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY
- KPC-3-producing ST167 Escherichia coli from mussels bought at a retail market in Tunisia
- (2017) Yosra Mani et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- The Epidemiology of Carbapenem-Resistant Enterobacteriaceae: The Impact and Evolution of a Global Menace
- (2017) Latania K. Logan et al. JOURNAL OF INFECTIOUS DISEASES
- Klebsiella pneumoniae Carbapenemase-2 (KPC-2), Substitutions at Ambler Position Asp179, and Resistance to Ceftazidime-Avibactam: Unique Antibiotic-Resistant Phenotypes Emerge from β-Lactamase Protein Engineering
- (2017) Melissa D. Barnes et al. mBio
- Molecular characterisation of carbapenemases in urban pigeon droppings in France and Algeria
- (2017) Houda Morakchi et al. Journal of Global Antimicrobial Resistance
- Emergence of Ceftazidime-Avibactam Resistance and Restoration of Carbapenem Susceptibility in Klebsiella pneumoniae Carbapenemase-Producing K pneumoniae: A Case Report and Review of Literature
- (2017) Ryan K. Shields et al. Open Forum Infectious Diseases
- Prevalence of ESBL and/or carbapenemase-producing Escherichia coli isolated from yellow–legged gulls from Barcelona, Spain
- (2016) Andrea Vergara et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Detection of Carbapenemase Genes in Aquatic Environments in Rio de Janeiro, Brazil
- (2016) Carlos Felipe Machado de Araujo et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Emergence of Ceftazidime-Avibactam Resistance Due to Plasmid-Borne bla KPC-3 Mutations during Treatment of Carbapenem-Resistant Klebsiella pneumoniae Infections
- (2016) Ryan K. Shields et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- High Rates of Nonsusceptibility to Ceftazidime-avibactam and Identification of New Delhi Metallo-β-lactamase Production inEnterobacteriaceaeBloodstream Infections at a Major Cancer Center: Table 1.
- (2016) Samuel L. Aitken et al. CLINICAL INFECTIOUS DISEASES
- Structural and Functional Aspects of Class A Carbapenemases
- (2016) Thierry Naas et al. CURRENT DRUG TARGETS
- A ten-year surveillance study of carbapenemase-producing Klebsiella pneumoniae in a tertiary care Greek university hospital: predominance of KPC- over VIM- or NDM-producing isolates
- (2016) Aikaterini Spyropoulou et al. JOURNAL OF MEDICAL MICROBIOLOGY
- Global Dissemination of Carbapenemase-Producing Klebsiella pneumoniae: Epidemiology, Genetic Context, Treatment Options, and Detection Methods
- (2016) Chang-Ro Lee et al. Frontiers in Microbiology
- EPIDEMIOLOGY OF CARBAPENEM RESISTANT KLEBSIELLA PNEUMONIAE INFECTIONS IN MEDITERRANEAN COUNTRIES
- (2016) Corrado Girmenia et al. Mediterranean Journal of Hematology and Infectious Diseases
- First Report of Ceftazidime-Avibactam Resistance in a KPC-3-Expressing Klebsiella pneumoniae Isolate
- (2015) Romney M. Humphries et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Multiyear, Multinational Survey of the Incidence and Global Distribution of Metallo-β-Lactamase-Producing Enterobacteriaceae and Pseudomonas aeruginosa
- (2015) Krystyna M. Kazmierczak et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- In VitroSelection of Ceftazidime-Avibactam Resistance in Enterobacteriaceae with KPC-3 Carbapenemase
- (2015) David M. Livermore et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- A Structure-Based Classification of Class A β-Lactamases, a Broadly Diverse Family of Enzymes
- (2015) Alain Philippon et al. CLINICAL MICROBIOLOGY REVIEWS
- Activity of ceftazidime/avibactam against isogenic strains ofEscherichia colicontaining KPC and SHV β-lactamases with single amino acid substitutions in the Ω-loop
- (2015) Marisa L. Winkler et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- The β-Lactams Strike Back: Ceftazidime-Avibactam
- (2015) Evan J. Zasowski et al. PHARMACOTHERAPY
- Natural Variants of the KPC-2 Carbapenemase have Evolved Increased Catalytic Efficiency for Ceftazidime Hydrolysis at the Cost of Enzyme Stability
- (2015) Shrenik C. Mehta et al. PLoS Pathogens
- Incidence of colonization and bloodstream infection with carbapenem-resistantEnterobacteriaceaein children receiving antineoplastic chemotherapy in Italy
- (2015) Desiree Caselli et al. Infectious Diseases
- Inhibition of Klebsiella β-Lactamases (SHV-1 and KPC-2) by Avibactam: A Structural Study
- (2015) Nikhil P. Krishnan et al. PLoS One
- Infections by carbapenem-resistant Klebsiella pneumoniae in SCT recipients: a nationwide retrospective survey from Italy
- (2014) C Girmenia et al. BONE MARROW TRANSPLANTATION
- The Global Challenge of Carbapenem-Resistant Enterobacteriaceae in Transplant Recipients and Patients With Hematologic Malignancies
- (2014) M. J. Satlin et al. CLINICAL INFECTIOUS DISEASES
- Carbapenemases in Enterobacteriaceae: Types and molecular epidemiology
- (2014) Luis Martínez-Martínez et al. ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
- Infection with Klebsiella pneumoniae carbapenemase (KPC)-producing Klebsiella pneumoniae in cancer patients
- (2014) M. P. Freire et al. EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
- Persistence of Klebsiella pneumoniae ST258 as the predominant clone of carbapenemase-producing Enterobacteriaceae in post-acute-care hospitals in Israel, 2008-13
- (2014) A. Adler et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Ceftazidime-Avibactam: a Novel Cephalosporin/β-lactamase Inhibitor Combination
- (2013) George G. Zhanel et al. DRUGS
- Clinical epidemiology of the global expansion of Klebsiella pneumoniae carbapenemases
- (2013) L Silvia Munoz-Price et al. LANCET INFECTIOUS DISEASES
- KPC-9, a Novel Carbapenemase from Clinical Specimens in Israel
- (2012) Carlos Hidalgo-Grass et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Predictors of Mortality in Bloodstream Infections Caused by Klebsiella pneumoniae Carbapenemase-Producing K. pneumoniae: Importance of Combination Therapy
- (2012) M. Tumbarello et al. CLINICAL INFECTIOUS DISEASES
- Exploring the Role of a Conserved Class A Residue in the Ω-Loop of KPC-2 β-Lactamase
- (2012) Peter S. Levitt et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Infections Caused by Carbapenem-resistant Gram-negative Pathogens in Hospitalized Children
- (2012) Helena C. Maltezou et al. PEDIATRIC INFECTIOUS DISEASE JOURNAL
- Ligand-Dependent Disorder of the Ω Loop Observed in Extended-Spectrum SHV-Type β-Lactamase
- (2011) Jared M. Sampson et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Activities of NXL104 Combinations with Ceftazidime and Aztreonam against Carbapenemase-ProducingEnterobacteriaceae
- (2010) David M. Livermore et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Substrate Selectivity and a Novel Role in Inhibitor Discrimination by Residue 237 in the KPC-2 -Lactamase
- (2010) K. M. Papp-Wallace et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Multiple Global Suppressors of Protein Stability Defects Facilitate the Evolution of Extended-Spectrum TEM β-Lactamases
- (2010) Nicholas G. Brown et al. JOURNAL OF MOLECULAR BIOLOGY
- Elucidating the role of Trp105 in the KPC-2 β-lactamase
- (2010) Krisztina M. Papp-Wallace et al. PROTEIN SCIENCE
- Detection of KPC in Acinetobacter spp. in Puerto Rico
- (2009) I. E. Robledo et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Characterization of blaKPC-containing Klebsiella pneumoniae isolates detected in different institutions in the Eastern USA
- (2009) Andrea Endimiani et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Structural and Biochemical Evidence That a TEM-1 β-Lactamase N170G Active Site Mutant Acts via Substrate-assisted Catalysis
- (2009) Nicholas G. Brown et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The real threat of Klebsiella pneumoniae carbapenemase-producing bacteria
- (2009) Patrice Nordmann et al. LANCET INFECTIOUS DISEASES
- Genetic and Structural Insights into the Dissemination Potential of the Extremely Broad-Spectrum Class A -Lactamase KPC-2 Identified in an Escherichia coli Strain and an Enterobacter cloacae Strain Isolated from the Same Patient in France
- (2008) S. Petrella et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- First Report on a Hyperepidemic Clone of KPC-3-Producing Klebsiella pneumoniae in Israel Genetically Related to a Strain Causing Outbreaks in the United States
- (2008) S. Navon-Venezia et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Phenotypic and Enzymatic Comparative Analysis of the Novel KPC Variant KPC-5 and Its Evolutionary Variants, KPC-2 and KPC-4
- (2008) D. J. Wolter et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
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