标题
Physiology and pharmacology of amyloid precursor protein
作者
关键词
-
出版物
PHARMACOLOGY & THERAPEUTICS
Volume 235, Issue -, Pages 108122
出版商
Elsevier BV
发表日期
2022-02-02
DOI
10.1016/j.pharmthera.2022.108122
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- O-GlcNAcylation ameliorates the pathological manifestations of Alzheimer’s disease by inhibiting necroptosis
- (2021) Jinsu Park et al. Science Advances
- Loss of all three APP family members during development impairs synaptic function and plasticity, disrupts learning, and causes an autism‐like phenotype
- (2021) Vicky Steubler et al. EMBO JOURNAL
- Secreted Amyloid Precursor Protein-Alpha Enhances LTP Through the Synthesis and Trafficking of Ca2+-Permeable AMPA Receptors
- (2021) Rhys W. Livingstone et al. Frontiers in Molecular Neuroscience
- Revisiting FDA Approval of Aducanumab
- (2021) G. Caleb Alexander et al. NEW ENGLAND JOURNAL OF MEDICINE
- The amyloid precursor protein is a conserved Wnt receptor
- (2021) Tengyuan Liu et al. eLife
- Can platelet activation result in increased plasma Aβ levels and contribute to the pathogenesis of Alzheimer’s disease?
- (2021) Manuel Glauco Carbone et al. AGEING RESEARCH REVIEWS
- The β-secretase BACE1 in Alzheimer’s disease
- (2020) Harald Hampel et al. BIOLOGICAL PSYCHIATRY
- Interactions between amyloid precursor protein-like (APPL) and MAGUK scaffolding proteins contribute to appetitive long-term memory in Drosophila melanogaster
- (2020) Bryon Silva et al. JOURNAL OF NEUROGENETICS
- O-GlcNAcylation as a Therapeutic Target for Alzheimer’s Disease
- (2020) Jinsu Park et al. NEUROMOLECULAR MEDICINE
- Rivastigmine modifies the α-secretase pathway and potentially early Alzheimer’s disease
- (2020) Balmiki Ray et al. Translational Psychiatry
- Neuronal Aquaporin 1 Inhibits Amyloidogenesis by Suppressing the Interaction Between Beta-Secretase and Amyloid Precursor Protein
- (2020) Jinsu Park et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Mitochondria dysfunction in the pathogenesis of Alzheimer’s disease: recent advances
- (2020) Wenzhang Wang et al. Molecular Neurodegeneration
- Novel Anti-Alzheimer’s Therapeutic Molecules Targeting Amyloid Precursor Protein Processing
- (2020) Md. Sahab Uddin et al. Oxidative Medicine and Cellular Longevity
- Amyloid precursor protein 770 is specifically expressed and released from platelets
- (2020) Saori Miura et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Amyloid precursor protein-b facilitates cell adhesion during early development in zebrafish
- (2020) Rakesh Kumar Banote et al. Scientific Reports
- Amyloid Precursor Protein (APP) Controls the Expression of the Transcriptional Activator Neuronal PAS Domain Protein 4 (NPAS4) and Synaptic GABA Release
- (2020) Rémi Opsomer et al. eNeuro
- Accumulation of amyloid precursor protein C-terminal fragments triggers mitochondrial structure, function, and mitophagy defects in Alzheimer’s disease models and human brains
- (2020) Loan Vaillant-Beuchot et al. ACTA NEUROPATHOLOGICA
- White matter and neurological disorders
- (2020) Han-Gyu Bae et al. ARCHIVES OF PHARMACAL RESEARCH
- APP Binds to the EGFR Ligands HB-EGF and EGF, Acting Synergistically with EGF to Promote ERK Signaling and Neuritogenesis
- (2020) Joana F. da Rocha et al. MOLECULAR NEUROBIOLOGY
- APP Family Regulates Neuronal Excitability and Synaptic Plasticity but Not Neuronal Survival
- (2020) Sang Hun Lee et al. NEURON
- BACE inhibition causes rapid, regional, and non-progressive volume reduction in Alzheimer’s disease brain
- (2020) Cyrille Sur et al. BRAIN
- The Drosophila amyloid precursor protein homologue mediates neuronal survival and neuroglial interactions
- (2020) Irini A. Kessissoglou et al. PLOS BIOLOGY
- Functions of amyloid precursor protein in metabolic diseases
- (2020) Yanjun Guo et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Therapeutic Approaches to Alzheimer’s Disease Through Modulation of NRF2
- (2019) Gahee Bahn et al. NEUROMOLECULAR MEDICINE
- Secreted amyloid-β precursor protein functions as a GABABR1a ligand to modulate synaptic transmission
- (2019) Heather C. Rice et al. SCIENCE
- Glutamate receptor trafficking and protein synthesis mediate the facilitation of ltp by secreted amyloid precursor protein-alpha
- (2019) Bruce G. Mockett et al. JOURNAL OF NEUROSCIENCE
- ADAM10 in Alzheimer's disease: Pharmacological modulation by natural compounds and its role as a peripheral marker
- (2019) Patricia Regina Manzine et al. BIOMEDICINE & PHARMACOTHERAPY
- Preliminary Results of a Trial of Atabecestat in Preclinical Alzheimer’s Disease
- (2019) David Henley et al. NEW ENGLAND JOURNAL OF MEDICINE
- Randomized Trial of Verubecestat for Prodromal Alzheimer’s Disease
- (2019) Michael F. Egan et al. NEW ENGLAND JOURNAL OF MEDICINE
- NRF2/ARE pathway negatively regulates BACE1 expression and ameliorates cognitive deficits in mouse Alzheimer’s models
- (2019) Gahee Bahn et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Alzheimer Disease: An Update on Pathobiology and Treatment Strategies
- (2019) Justin M. Long et al. CELL
- Efficacy and Safety of Lanabecestat for Treatment of Early and Mild Alzheimer Disease
- (2019) Alette M. Wessels et al. JAMA Neurology
- Drosophila Full-Length Amyloid Precursor Protein Is Required for Visual Working Memory and Prevents Age-Related Memory Impairment
- (2018) Franziska Rieche et al. CURRENT BIOLOGY
- Mitochondrial Dysfunction in Parkinson’s Disease: New Mechanistic Insights and Therapeutic Perspectives
- (2018) Jin-Sung Park et al. Current Neurology and Neuroscience Reports
- Distinct in vivo roles of secreted APP ectodomain variants APPsα and APPsβ in regulation of spine density, synaptic plasticity, and cognition
- (2018) Max C Richter et al. EMBO JOURNAL
- Amyloid Precursor Protein Dimerisation Reduces Neurite Outgrowth
- (2018) Luan Luu et al. MOLECULAR NEUROBIOLOGY
- Randomized Trial of Verubecestat for Mild-to-Moderate Alzheimer’s Disease
- (2018) Michael F. Egan et al. NEW ENGLAND JOURNAL OF MEDICINE
- Notch signaling and neuronal death in stroke
- (2018) Thiruma V. Arumugam et al. PROGRESS IN NEUROBIOLOGY
- Lentivirus-mediated expression of human secreted amyloid precursor protein-alpha prevents development of memory and plasticity deficits in a mouse model of Alzheimer's disease
- (2018) Valerie T. Y. Tan et al. Molecular Brain
- Reconsideration of Amyloid Hypothesis and Tau Hypothesis in Alzheimer's Disease
- (2018) Fuyuki Kametani et al. Frontiers in Neuroscience
- Amyloid precursor protein is required for in vitro platelet adhesion to amyloid peptides and potentiation of thrombus formation
- (2018) Caterina Visconte et al. CELLULAR SIGNALLING
- The BACE1-PSEN-AβPP Regulatory Axis has an Ancient Role in Response to Low Oxygen/Oxidative Stress
- (2018) Seyyed Hani Moussavi Nik et al. JOURNAL OF ALZHEIMERS DISEASE
- Metabolic Syndrome and Amyloid Accumulation in the Aging Brain
- (2018) Gabriela Gomez et al. JOURNAL OF ALZHEIMERS DISEASE
- Amyloid precursor protein-mediated mitochondrial regulation and Alzheimer's disease
- (2018) M Isabel G Lopez Sanchez et al. BRITISH JOURNAL OF PHARMACOLOGY
- Mitochondria as a therapeutic target for common pathologies
- (2018) Michael P. Murphy et al. NATURE REVIEWS DRUG DISCOVERY
- The physiological role of the amyloid precursor protein as an adhesion molecule in the developing nervous system
- (2017) Lucas J. Sosa et al. JOURNAL OF NEUROCHEMISTRY
- Inhibition of Drp1 Ameliorates Synaptic Depression, Aβ Deposition, and Cognitive Impairment in an Alzheimer's Disease Model
- (2017) Seung Hyun Baek et al. JOURNAL OF NEUROSCIENCE
- Proteases and protease inhibitors in infectious diseases
- (2017) Ayodeji A. Agbowuro et al. MEDICINAL RESEARCH REVIEWS
- Not just amyloid: physiological functions of the amyloid precursor protein family
- (2017) Ulrike C. Müller et al. NATURE REVIEWS NEUROSCIENCE
- The role of astrocytes in amyloid production and Alzheimer's disease
- (2017) Georgia R. Frost et al. Open Biology
- Therapeutic Potential of Secreted Amyloid Precursor Protein APPsα
- (2017) Bruce G. Mockett et al. Frontiers in Molecular Neuroscience
- Platelet Amyloid Precursor Protein Isoform Expression in Alzheimer's Disease: Evidence for Peripheral Marker
- (2017) A. Vignini et al. INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY
- Amyloid precursor protein maintains constitutive and adaptive plasticity of dendritic spines in adult brain by regulating D‐serine homeostasis
- (2016) Chengyu Zou et al. EMBO JOURNAL
- APP Regulates Microglial Phenotype in a Mouse Model of Alzheimer's Disease
- (2016) G. D. Manocha et al. JOURNAL OF NEUROSCIENCE
- Restoring Soluble Amyloid Precursor Protein α Functions as a Potential Treatment for Alzheimer's Disease
- (2016) Ahsan Habib et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Amyloid β precursor protein regulates neuron survival and maturation in the adult mouse brain
- (2016) Shiwei Wang et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- Notch signalling in context
- (2016) Sarah J. Bray NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Role of Drosophila Amyloid Precursor Protein in Memory Formation
- (2016) Thomas Preat et al. Frontiers in Molecular Neuroscience
- Neuronal migration during development and the amyloid precursor protein
- (2016) Philip F Copenhaver et al. Current Opinion in Insect Science
- Viral gene transfer of APPsα rescues synaptic failure in an Alzheimer’s disease mouse model
- (2015) Romain Fol et al. ACTA NEUROPATHOLOGICA
- Pin1 promotes neuronal death in stroke by stabilizing Notch intracellular domain
- (2015) Sang-Ha Baik et al. ANNALS OF NEUROLOGY
- Cellular Functions of the Amyloid Precursor Protein from Development to Dementia
- (2015) Rik van der Kant et al. DEVELOPMENTAL CELL
- The Full-Length Form of the Drosophila Amyloid Precursor Protein Is Involved in Memory Formation
- (2015) I. Bourdet et al. JOURNAL OF NEUROSCIENCE
- APP intracellular domain–WAVE1 pathway reduces amyloid-β production
- (2015) Ilaria Ceglia et al. NATURE MEDICINE
- Emerging roles of the γ-secretase-notch axis in inflammation
- (2015) Yi-Lin Cheng et al. PHARMACOLOGY & THERAPEUTICS
- APP intracellular domain acts as a transcriptional regulator of miR-663 suppressing neuronal differentiation
- (2015) R Shu et al. Cell Death & Disease
- Acute function of secreted amyloid precursor protein fragment APPsα in synaptic plasticity
- (2014) Meike Hick et al. ACTA NEUROPATHOLOGICA
- Amyloid precursor protein and neural development
- (2014) M. Nicolas et al. DEVELOPMENT
- The Aβ-clearance protein transthyretin, like neprilysin, is epigenetically regulated by the amyloid precursor protein intracellular domain
- (2014) Caroline Kerridge et al. JOURNAL OF NEUROCHEMISTRY
- Insights into the physiological function of the β-amyloid precursor protein: beyond Alzheimer's disease
- (2014) Edgar Dawkins et al. JOURNAL OF NEUROCHEMISTRY
- Amyloid Precursor Protein Dimerization and Synaptogenic Function Depend on Copper Binding to the Growth Factor-Like Domain
- (2014) F. Baumkotter et al. JOURNAL OF NEUROSCIENCE
- The Amyloid Precursor Protein Controls Adult Hippocampal Neurogenesis through GABAergic Interneurons
- (2014) B. Wang et al. JOURNAL OF NEUROSCIENCE
- Increased CSF APPs- levels in patients with Alzheimer disease treated with acitretin
- (2014) K. Endres et al. NEUROLOGY
- Wnt signaling in the nervous system and in Alzheimer's disease
- (2014) N. C. Inestrosa et al. Journal of Molecular Cell Biology
- Comparative analysis of single and combined APP/APLP knockouts reveals reduced spine density in APP-KO mice that is prevented by APPsα expression
- (2014) Sascha W Weyer et al. Acta Neuropathologica Communications
- Upregulation of PGC-1α expression by Alzheimer's disease-associated pathway: presenilin 1/amyloid precursor protein (APP)/intracellular domain of APP
- (2013) Ari Robinson et al. AGING CELL
- Major Carboxyl Terminal Fragments Generated by γ-Secretase Processing of the Alzheimer Amyloid Precursor Are 50 and 51 Amino Acids Long
- (2013) Inga Pinnix et al. AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY
- The zebrafish amyloid precursor protein-b is required for motor neuron guidance and synapse formation
- (2013) Alexandra Abramsson et al. DEVELOPMENTAL BIOLOGY
- Redundancy and divergence in the amyloid precursor protein family
- (2013) S. Ali M. Shariati et al. FEBS LETTERS
- Microglia, neuroinflammation, and beta-amyloid protein in Alzheimer's disease
- (2013) Zhiyou Cai et al. INTERNATIONAL JOURNAL OF NEUROSCIENCE
- Loss of Bace2 in zebrafish affects melanocyte migration and is distinct from Bace1 knock out phenotypes
- (2013) Frauke van Bebber et al. JOURNAL OF NEUROCHEMISTRY
- Chronic 5-HT4 receptor activation decreases Aβ production and deposition in hAPP/PS1 mice
- (2013) Ina Tesseur et al. NEUROBIOLOGY OF AGING
- A Phase 3 Trial of Semagacestat for Treatment of Alzheimer's Disease
- (2013) Rachelle S. Doody et al. NEW ENGLAND JOURNAL OF MEDICINE
- WNT signaling in neuronal maturation and synaptogenesis
- (2013) Silvana B. Rosso et al. Frontiers in Cellular Neuroscience
- Physiological Functions of APP Family Proteins
- (2013) U. C. Muller et al. Cold Spring Harbor Perspectives in Medicine
- The Drosophila Homologue of the Amyloid Precursor Protein Is a Conserved Modulator of Wnt PCP Signaling
- (2013) Alessia Soldano et al. PLOS BIOLOGY
- APP interacts with LRP4 and agrin to coordinate the development of the neuromuscular junction in mice
- (2013) Hong Y Choi et al. eLife
- Oxidative lipid modification of nicastrin enhances amyloidogenic γ-secretase activity in Alzheimer’s disease
- (2012) A-Ryeong Gwon et al. AGING CELL
- Safety and Tolerability of the γ-Secretase Inhibitor Avagacestat in a Phase 2 Study of Mild to Moderate Alzheimer Disease
- (2012) Vladimir Coric et al. ARCHIVES OF NEUROLOGY
- BMS-708,163 Targets Presenilin and Lacks Notch-Sparing Activity
- (2012) Christina J. Crump et al. BIOCHEMISTRY
- A ternary complex consisting of AICD, FE65, and TIP60 down-regulates Stathmin1
- (2012) Thorsten Müller et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- Characterisation of the effect of knockout of the amyloid precursor protein on outcome following mild traumatic brain injury
- (2012) Frances Corrigan et al. BRAIN RESEARCH
- Expression and function of APP and its metabolites outside the central nervous system
- (2012) Kendra L. Puig et al. EXPERIMENTAL GERONTOLOGY
- APL-1, the Alzheimer's Amyloid Precursor Protein in Caenorhabditis elegans, Modulates Multiple Metabolic Pathways Throughout Development
- (2012) C. Y. Ewald et al. GENETICS
- Pan-Neuronal Expression of APL-1, an APP-Related Protein, Disrupts Olfactory, Gustatory, and Touch Plasticity in Caenorhabditis elegans
- (2012) C. Y. Ewald et al. JOURNAL OF NEUROSCIENCE
- Utility of an improved model of amyloid-beta (Aβ1-42) toxicity in Caenorhabditis elegans for drug screening for Alzheimer’s disease
- (2012) Gawain McColl et al. Molecular Neurodegeneration
- A mutation in APP protects against Alzheimer’s disease and age-related cognitive decline
- (2012) Thorlakur Jonsson et al. NATURE
- Amyloid precursor proteins are protective in Drosophila models of progressive neurodegeneration
- (2012) Jill S. Wentzell et al. NEUROBIOLOGY OF DISEASE
- Amyloid Precursor Protein (APP) Mediated Regulation of Ganglioside Homeostasis Linking Alzheimer's Disease Pathology with Ganglioside Metabolism
- (2012) Marcus O. W. Grimm et al. PLoS One
- Regulation of Neuronal APL-1 Expression by Cholesterol Starvation
- (2012) Mary Wiese et al. PLoS One
- Amyloid Precursor Protein and Proinflammatory Changes Are Regulated in Brain and Adipose Tissue in a Murine Model of High Fat Diet-Induced Obesity
- (2012) Kendra L. Puig et al. PLoS One
- APP Knockout Mice Experience Acute Mortality as the Result of Ischemia
- (2012) Maya A. Koike et al. PLoS One
- Alzheimer disease and platelets: how’s that relevant
- (2012) Silvia Catricala et al. Immunity & Ageing
- Amyloid Precursor Protein Processing and Alzheimer's Disease
- (2011) Richard J. O'Brien et al. Annual Review of Neuroscience
- Comparative transcriptome profiling of amyloid precursor protein family members in the adult cortex
- (2011) Dorothee Aydin et al. BMC GENOMICS
- APP and APLP2 are essential at PNS and CNS synapses for transmission, spatial learning and LTP
- (2011) Sascha W Weyer et al. EMBO JOURNAL
- Amyloid Precursor Protein Revisited
- (2011) Qinxi Guo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Selective Interaction of Amyloid Precursor Protein with Different Isoforms of Neural Cell Adhesion Molecule
- (2011) Ke-ping Chen et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Plasmalogen synthesis is regulated via alkyl-dihydroxyacetonephosphate-synthase by amyloid precursor protein processing and is affected in Alzheimer’s disease
- (2011) Marcus O. W. Grimm et al. JOURNAL OF NEUROCHEMISTRY
- The physiology of the β-amyloid precursor protein intracellular domain AICD
- (2011) Raphaëlle Pardossi-Piquard et al. JOURNAL OF NEUROCHEMISTRY
- Drosophila Amyloid Precursor Protein-Like Is Required for Long-Term Memory
- (2011) V. Goguel et al. JOURNAL OF NEUROSCIENCE
- Biology and pathophysiology of the amyloid precursor protein
- (2011) Hui Zheng et al. Molecular Neurodegeneration
- The APP intracellular domain (AICD) potentiates ER stress-induced apoptosis
- (2011) Donat Kögel et al. NEUROBIOLOGY OF AGING
- EVP-6124, a novel and selective α7 nicotinic acetylcholine receptor partial agonist, improves memory performance by potentiating the acetylcholine response of α7 nicotinic acetylcholine receptors
- (2011) Jos Prickaerts et al. NEUROPHARMACOLOGY
- Determination of the Proteolytic Cleavage Sites of the Amyloid Precursor-Like Protein 2 by the Proteases ADAM10, BACE1 and γ-Secretase
- (2011) Sebastian Hogl et al. PLoS One
- The roles of amyloid precursor protein (APP) in neurogenesis
- (2011) Zhi-dong Zhou et al. Cell Adhesion & Migration
- Caenorhabditis elegans as a model organism to study APP function
- (2011) Collin Y. Ewald et al. EXPERIMENTAL BRAIN RESEARCH
- Analysis of amyloid precursor protein function in Drosophila melanogaster
- (2011) Burkhard Poeck et al. EXPERIMENTAL BRAIN RESEARCH
- Secretases as therapeutic targets for Alzheimer’s disease
- (2010) Ha-Na Woo et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Activation of α7 nicotinic receptor affects APP processing by regulating secretase activity in SH-EP1-α7 nAChR-hAPP695 cells
- (2010) Hui Zhen Nie et al. BRAIN RESEARCH
- Retinoic acid receptor-α signalling antagonizes both intracellular and extracellular amyloid-β production and prevents neuronal cell death caused by amyloid-β
- (2010) C. I. Jarvis et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- The amyloid precursor protein intracellular domain alters gene expression and induces neuron-specific apoptosis
- (2010) Takeshi Ohkawara et al. GENE
- Amyloid-β Protein Oligomer at Low Nanomolar Concentrations Activates Microglia and Induces Microglial Neurotoxicity
- (2010) Izumi Maezawa et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Deletion of M1 Muscarinic Acetylcholine Receptors Increases Amyloid Pathology In Vitro and In Vivo
- (2010) A. A. Davis et al. JOURNAL OF NEUROSCIENCE
- Protein aggregation diseases: pathogenicity and therapeutic perspectives
- (2010) Adriano Aguzzi et al. NATURE REVIEWS DRUG DISCOVERY
- S100a9 Knockdown Decreases the Memory Impairment and the Neuropathology in Tg2576 Mice, AD Animal Model
- (2010) Tae-Young Ha et al. PLoS One
- Intracellular Trafficking and Synaptic Function of APL-1 in Caenorhabditis elegans
- (2010) Mary Wiese et al. PLoS One
- Soluble amyloid precursor protein (APP) regulates transthyretin and Klotho gene expression without rescuing the essential function of APP
- (2010) H. Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Neurons Generated from APP/APLP1/APLP2 Triple Knockout Embryonic Stem Cells Behave NormallyIn VitroandIn Vivo: Lack of Evidence for a Cell Autonomous Role of APP in Neuronal Differentiation
- (2010) Bruno A. Bergmans et al. STEM CELLS
- A γ-secretase inhibitor decreases amyloid-β production in the central nervous system
- (2009) Randall J. Bateman et al. ANNALS OF NEUROLOGY
- Mitochondrial dysfunction is a trigger of Alzheimer's disease pathophysiology
- (2009) Paula I. Moreira et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Netrin-1 interacts with amyloid precursor protein and regulates amyloid-β production
- (2009) F C Lourenço et al. CELL DEATH AND DIFFERENTIATION
- Amyloid precursor protein is required for convergent-extension movements during Zebrafish development
- (2009) Powrnima Joshi et al. DEVELOPMENTAL BIOLOGY
- Epigenetic control of aquaporin 1 expression by the amyloid precursor protein
- (2009) Sandra Huysseune et al. FASEB JOURNAL
- The Effects of Amyloid Precursor Protein on Postsynaptic Composition and Activity
- (2009) Hyang-Sook Hoe et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mitochondrial accumulation of APP and Aβ: significance for Alzheimer disease pathogenesis
- (2009) Pavel F. Pavlov et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Amyloid precursor protein promotes endoplasmic reticulum stress-induced cell death via C/EBP homologous protein-mediated pathway
- (2009) Keita Takahashi et al. JOURNAL OF NEUROCHEMISTRY
- Amyloid precursor protein 695 associates with assembled NR2A- and NR2B-containing NMDA receptors to result in the enhancement of their cell surface delivery
- (2009) Sarah L. Cousins et al. JOURNAL OF NEUROCHEMISTRY
- Amyloid Precursor Protein Regulates Cav1.2 L-type Calcium Channel Levels and Function to Influence GABAergic Short-Term Plasticity
- (2009) L. Yang et al. JOURNAL OF NEUROSCIENCE
- Interaction of Reelin with Amyloid Precursor Protein Promotes Neurite Outgrowth
- (2009) H.-S. Hoe et al. JOURNAL OF NEUROSCIENCE
- Presynaptic and Postsynaptic Interaction of the Amyloid Precursor Protein Promotes Peripheral and Central Synaptogenesis
- (2009) Z. Wang et al. JOURNAL OF NEUROSCIENCE
- Maturation of BRI2 generates a specific inhibitor that reduces APP processing at the plasma membrane and in endocytic vesicles
- (2009) Shuji Matsuda et al. NEUROBIOLOGY OF AGING
- Contribution of γ-secretase to calcium-mediated cell death
- (2009) Yun-Hyung Choi et al. NEUROSCIENCE LETTERS
- Alzheimer's disease-like pathological features in transgenic mice expressing the APP intracellular domain
- (2009) K. Ghosal et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Recessive Mutation in the APP Gene with Dominant-Negative Effect on Amyloidogenesis
- (2009) G. Di Fede et al. SCIENCE
- The netrin protein family
- (2009) Sathyanath Rajasekharan et al. GENOME BIOLOGY
- Close association of water channel AQP1 with amyloid-β deposition in Alzheimer disease brains
- (2008) Tamako Misawa et al. ACTA NEUROPATHOLOGICA
- Neprilysin gene expression requires binding of the amyloid precursor protein intracellular domain to its promoter: implications for Alzheimer disease
- (2008) Nikolai D Belyaev et al. EMBO REPORTS
- Increased AICD generation does not result in increased nuclear translocation or activation of target gene transcription
- (2008) E WALDRON et al. EXPERIMENTAL CELL RESEARCH
- Etazolate, a neuroprotective drug linking GABAAreceptor pharmacology to amyloid precursor protein processing
- (2008) Maryline Marcade et al. JOURNAL OF NEUROCHEMISTRY
- Swedish amyloid precursor protein mutation increases cell cycle-related proteins in vitro and in vivo
- (2008) Kwang-Woo Ahn et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Evidence that the Amyloid beta Precursor Protein-intracellular domain lowers the stress threshold of neurons and has a "regulated" transcriptional role
- (2008) Luca Giliberto et al. Molecular Neurodegeneration
- Evidence that γ-secretase mediates oxidative stress-induced β-secretase expression in Alzheimer's disease
- (2008) Dong-Gyu Jo et al. NEUROBIOLOGY OF AGING
- Endogenous secreted amyloid precursor protein-α regulates hippocampal NMDA receptor function, long-term potentiation and spatial memory
- (2008) Chanel J. Taylor et al. NEUROBIOLOGY OF DISEASE
- Neurotoxic effects induced by the Drosophila amyloid-β peptide suggest a conserved toxic function
- (2008) Katia Carmine-Simmen et al. NEUROBIOLOGY OF DISEASE
- Overexpression of wild-type human APP in mice causes cognitive deficits and pathological features unrelated to Aβ levels
- (2008) Ana-María Simón et al. NEUROBIOLOGY OF DISEASE
- The intracellular domain of amyloid precursor protein induces neuron-specific apoptosis
- (2008) Kohzo Nakayama et al. NEUROSCIENCE LETTERS
- Amyloid Precursor Protein Expression Is Upregulated in Adipocytes in Obesity
- (2008) Yong-Ho Lee et al. Obesity
- Amyloid- overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins
- (2008) X. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Embryonic Stem Cell-Derived Neurons as a Cellular System to Study Gene Function: Lack of Amyloid Precursor Proteins APP and APLP2 Leads to Defective Synaptic Transmission
- (2008) Katrin Schrenk-Siemens et al. STEM CELLS
- Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease
- (2008) P. Hemachandra Reddy et al. TRENDS IN MOLECULAR MEDICINE
- Amyloid precursor protein knockout mice show age-dependent deficits in passive avoidance learning
- (2007) Yann Senechal et al. BEHAVIOURAL BRAIN RESEARCH
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