APP interacts with LRP4 and agrin to coordinate the development of the neuromuscular junction in mice

Structural basis of agrin-LRP4-MuSK signaling

(2012) Y. Zong et al.   GENES & DEVELOPMENT

Lrp4 is a retrograde signal for presynaptic differentiation at neuromuscular synapses

(2012) Norihiro Yumoto et al.   NATURE

Distinct Roles of Muscle and Motoneuron LRP4 in Neuromuscular Junction Formation

(2012) Haitao Wu et al.   NEURON

The extracellular region of Lrp4 is sufficient to mediate neuromuscular synapse formation

(2011) Andrea M. Gomez et al.   DEVELOPMENTAL DYNAMICS

APP and APLP2 are essential at PNS and CNS synapses for transmission, spatial learning and LTP

(2011) Sascha W Weyer et al.   EMBO JOURNAL

A valid mouse model of AGRIN-associated congenital myasthenic syndrome

(2011) L. P. Bogdanik et al.   HUMAN MOLECULAR GENETICS

Neuromuscular synaptic patterning requires the function of skeletal muscle dihydropyridine receptors

(2011) Fujun Chen et al.   NATURE NEUROSCIENCE

Lipoprotein receptors – an evolutionarily ancient multifunctional receptor family

(2010) Marco Dieckmann et al.   BIOLOGICAL CHEMISTRY

To build a synapse: signaling pathways in neuromuscular junction assembly

(2010) H. Wu et al.   DEVELOPMENT

Genetic Dissection of the Amyloid Precursor Protein in Developmental Function and Amyloid Pathogenesis

(2010) Hongmei Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ectodomains of the LDL Receptor-Related Proteins LRP1b and LRP4 Have Anchorage Independent Functions In Vivo

(2010) Martin F. Dietrich et al.   PLoS One

Lrp4 Regulates Initiation of Ureteric Budding and Is Crucial for Kidney Formation – A Mouse Model for Cenani-Lenz Syndrome

(2010) Courtney M. Karner et al.   PLoS One

Ubiquitin carboxyl-terminal hydrolase L1 is required for maintaining the structure and function of the neuromuscular junction

(2010) F. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ApoE4 reduces glutamate receptor function and synaptic plasticity by selectively impairing ApoE receptor recycling

(2010) Y. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Abnormal development of the neuromuscular junction in Nedd4-deficient mice

(2009) Yun Liu et al.   DEVELOPMENTAL BIOLOGY

Presynaptic and Postsynaptic Interaction of the Amyloid Precursor Protein Promotes Peripheral and Central Synaptogenesis

(2009) Z. Wang et al.   JOURNAL OF NEUROSCIENCE

Transmembrane agrin regulates dendritic filopodia and synapse formation in mature hippocampal neuron cultures

(2009) S. McCroskery et al.   NEUROSCIENCE

Reelin signaling antagonizes  -amyloid at the synapse

(2009) M. S. Durakoglugil et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lrp4 Is a Receptor for Agrin and Forms a Complex with MuSK

(2008) Natalie Kim et al.   CELL

Functional Role of Lipoprotein Receptors in Alzheimers Disease

(2008) Claus Pietrzik et al.   Current Alzheimer Research

Essential roles of the acetylcholine receptor  -subunit in neuromuscular synaptic patterning

(2008) Y. Liu et al.   DEVELOPMENT

apoE isoform–specific disruption of amyloid β peptide clearance from mouse brain

(2008) Rashid Deane et al.   JOURNAL OF CLINICAL INVESTIGATION

O-fucosylation of muscle agrin determines its ability to cluster acetylcholine receptors

(2008) Mi-Lyang Kim et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

LRP4 Serves as a Coreceptor of Agrin

(2008) Bin Zhang et al.   NEURON

Lrp4 Modulates Extracellular Integration of Cell Signaling Pathways in Development

(2008) Atsushi Ohazama et al.   PLoS One

Lipoprotein receptors and cholesterol in APP trafficking and proteolytic processing, implications for Alzheimer's disease

(2008) Maria-Paz Marzolo et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY