The amyloid precursor protein is a conserved Wnt receptor

Trafficking and proteolytic processing of amyloid precursor protein and secretases in Alzheimer's disease development: An up-to-date review

(2019) Melike Yuksel et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Amyloid β synaptotoxicity is Wnt-PCP dependent and blocked by fasudil

(2018) Katherine J. Sellers et al.   Alzheimers & Dementia

Role of Amyloid Precursor Protein (APP) and Its Derivatives in the Biology and Cell Fate Specification of Neural Stem Cells

(2018) Raquel Coronel et al.   MOLECULAR NEUROBIOLOGY

Knockout of Amyloid β Protein Precursor (APP) Expression Alters Synaptogenesis, Neurite Branching and Axonal Morphology of Hippocampal Neurons

(2018) Katherine A. Southam et al.   NEUROCHEMICAL RESEARCH

Endosomal sorting and trafficking, the retromer complex and neurodegeneration

(2018) Alana N. Vagnozzi et al.   MOLECULAR PSYCHIATRY

A role for APP in Wnt signalling links synapse loss with β-amyloid production

(2018) Christina Elliott et al.   Translational Psychiatry

RNA Docking and Local Translation Regulate Site-Specific Axon Remodeling In Vivo

(2017) Hovy Ho-Wai Wong et al.   NEURON

Mitochondrial SIRT3 Mediates Adaptive Responses of Neurons to Exercise and Metabolic and Excitatory Challenges

(2016) Aiwu Cheng et al.   Cell Metabolism

The amyloid hypothesis of Alzheimer's disease at 25 years

(2016) Dennis J Selkoe et al.   EMBO Molecular Medicine

Inhibition of Wnt signaling induces amyloidogenic processing of amyloid precursor protein and the production and aggregation of Amyloid-β (Aβ)42peptides

(2016) Cheril Tapia-Rojas et al.   JOURNAL OF NEUROCHEMISTRY

APP Receptor? To Be or Not To Be

(2016) Carole Deyts et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Role of Drosophila Amyloid Precursor Protein in Memory Formation

(2016) Thomas Preat et al.   Frontiers in Molecular Neuroscience

Analysis of Amyloid Precursor Protein Function in Drosophila melanogaster

(2016) Marlène Cassar et al.   Frontiers in Molecular Neuroscience

Cellular Functions of the Amyloid Precursor Protein from Development to Dementia

(2015) Rik van der Kant et al.   DEVELOPMENTAL CELL

Activation of the Wnt/β-catenin pathway represses the transcription of the β-amyloid precursor protein cleaving enzyme (BACE1) via binding of T-cell factor-4 to BACE1 promoter

(2015) Callum Parr et al.   FASEB JOURNAL

Beyond pathology: APP, brain development and Alzheimer's disease

(2014) Alessia Soldano et al.   CURRENT OPINION IN NEUROBIOLOGY

Amyloid precursor protein and neural development

(2014) M. Nicolas et al.   DEVELOPMENT

Adjudin protects against cerebral ischemia reperfusion injury by inhibition of neuroinflammation and blood-brain barrier disruption

(2014) Tengyuan Liu et al.   Journal of Neuroinflammation

Shedding of APP limits its synaptogenic activity and cell adhesion properties

(2014) Ronny Stahl et al.   Frontiers in Cellular Neuroscience

Redundancy and divergence in the amyloid precursor protein family

(2013) S. Ali M. Shariati et al.   FEBS LETTERS

Analysis of the Overall Structure of the Multi-Domain Amyloid Precursor Protein (APP)

(2013) Ina Coburger et al.   PLoS One

WNT signaling in neuronal maturation and synaptogenesis

(2013) Silvana B. Rosso et al.   Frontiers in Cellular Neuroscience

Physiological Functions of APP Family Proteins

(2013) U. C. Muller et al.   Cold Spring Harbor Perspectives in Medicine

Trafficking and Proteolytic Processing of APP

(2013) C. Haass et al.   Cold Spring Harbor Perspectives in Medicine

The Drosophila Homologue of the Amyloid Precursor Protein Is a Conserved Modulator of Wnt PCP Signaling

(2013) Alessia Soldano et al.   PLOS BIOLOGY

APP independent and dependent effects on neurite outgrowth are modulated by the receptor associated protein (RAP)

(2012) Andrew J. Billnitzer et al.   JOURNAL OF NEUROCHEMISTRY

Wnt Signaling in Vertebrate Neural Development and Function

(2012) Kimberly A. Mulligan et al.   Journal of Neuroimmune Pharmacology

The complex world of WNT receptor signalling

(2012) Christof Niehrs   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Ubiquilin-1 regulates amyloid precursor protein maturation and degradation by stimulating K63-linked polyubiquitination of lysine 688

(2012) A. El Ayadi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Relationships between the amyloid precursor protein and its various proteolytic fragments and neuronal systems

(2012) Sally Hunter et al.   Alzheimers Research & Therapy

The Wnt5/Planar Cell Polarity Pathway Regulates Axonal Development of the Drosophila Mushroom Body Neuron

(2011) K. Shimizu et al.   JOURNAL OF NEUROSCIENCE

Not(ch) just development: Notch signalling in the adult brain

(2011) Jessica L. Ables et al.   NATURE REVIEWS NEUROSCIENCE

Initiating and Growing an Axon

(2010) F. Polleux et al.   Cold Spring Harbor Perspectives in Biology

Establishment of Axon-Dendrite Polarity in Developing Neurons

(2009) Anthony P. Barnes et al.   Annual Review of Neuroscience

Subcellular localization and dimerization of APLP1 are strikingly different from APP and APLP2

(2009) D. Kaden et al.   JOURNAL OF CELL SCIENCE

Interaction of Reelin with Amyloid Precursor Protein Promotes Neurite Outgrowth

(2009) H.-S. Hoe et al.   JOURNAL OF NEUROSCIENCE

Secreted APP regulates the function of full-length APP in neurite outgrowth through interaction with integrin beta1

(2008) Tracy L Young-Pearse et al.   Neural Development