Development of Sesamol Carbamate-L-Phenylalanine Prodrug Targeting L-Type Amino Acid Transporter1 (LAT1) as a Potential Antiproliferative Agent against Melanoma
出版年份 2022 全文链接
标题
Development of Sesamol Carbamate-L-Phenylalanine Prodrug Targeting L-Type Amino Acid Transporter1 (LAT1) as a Potential Antiproliferative Agent against Melanoma
作者
关键词
-
出版物
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 23, Issue 15, Pages 8446
出版商
MDPI AG
发表日期
2022-08-01
DOI
10.3390/ijms23158446
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Route of intracellular uptake and cytotoxicity of sesamol, sesamin, and sesamolin in human melanoma SK-MEL-2 cells
- (2021) Tarapong Srisongkram et al. BIOMEDICINE & PHARMACOTHERAPY
- Toward a better understanding of metabolic and pharmacokinetic characteristics of low-solubility, low-permeability natural medicines
- (2020) Jie Yang et al. DRUG METABOLISM REVIEWS
- Tyrosine–Chlorambucil Conjugates Facilitate Cellular Uptake through L-Type Amino Acid Transporter 1 (LAT1) in Human Breast Cancer Cell Line MCF-7
- (2020) Piman Pocasap et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- L-Type amino acid transporter 1 as a target for drug delivery
- (2020) Elena Puris et al. PHARMACEUTICAL RESEARCH
- Delivery of Sesamol Using Polyethylene-Glycol-Functionalized Selenium Nanoparticles in Human Liver Cells in Culture
- (2019) Fuguo Liu et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Synthesis of CdS-modified chitosan quantum dots for the drug delivery of Sesamol
- (2019) Hani Nasser Abdelhamid et al. CARBOHYDRATE POLYMERS
- Sesamol, a major lignan in sesame seeds (Sesamum indicum): Anti-cancer properties and mechanisms of action
- (2019) Amin F. Majdalawieh et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Validation of Cell-Based Assay for Quantification of Sesamol Uptake and Its Application for Measuring Target Exposure
- (2019) Srisongkram et al. MOLECULES
- Identification Of Novel Sesamol Dimers With Unusual Methylenedioxy Ring-Opening Skeleton And Evaluation Of Their Antioxidant And Cytotoxic Activities
- (2019) Sudtha Murthy et al. CURRENT ORGANIC SYNTHESIS
- Role of L-Type Amino Acid Transporter 1 (LAT1) for the Selective Cytotoxicity of Sesamol in Human Melanoma Cells
- (2019) Tarapong Srisongkram et al. MOLECULES
- l-Type Amino Acid Transporter 1 (LAT1/Lat1)-Utilizing Prodrugs Can Improve the Delivery of Drugs into Neurons, Astrocytes and Microglia
- (2019) Johanna Huttunen et al. Scientific Reports
- Secondary Carbamate Linker Can Facilitate the Sustained Release of Dopamine from Brain-Targeted Prodrug
- (2018) Nikki A. Thiele et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Sesamol Inhibited Melanogenesis by Regulating Melanin-Related Signal Transduction in B16F10 Cells
- (2018) Po-Yuan Wu et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Structural properties for selective and efficient l -type amino acid transporter 1 (LAT1) mediated cellular uptake
- (2018) Jussi Kärkkäinen et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Role of l-Type Amino Acid Transporter 1 at the Inner Blood-Retinal Barrier in the Blood-to-Retina Transport of Gabapentin
- (2018) Shin-ichi Akanuma et al. MOLECULAR PHARMACEUTICS
- The expanding role of prodrugs in contemporary drug design and development
- (2018) Jarkko Rautio et al. NATURE REVIEWS DRUG DISCOVERY
- The Human SLC7A5 (LAT1): The Intriguing Histidine/Large Neutral Amino Acid Transporter and Its Relevance to Human Health
- (2018) Mariafrancesca Scalise et al. Frontiers in Chemistry
- Reevaluating the Substrate Specificity of the L-Type Amino Acid Transporter (LAT1)
- (2018) Huan-Chieh Chien et al. JOURNAL OF MEDICINAL CHEMISTRY
- Transport of Pregabalin Via L-Type Amino Acid Transporter 1 (SLC7A5) in Human Brain Capillary Endothelial Cell Line
- (2018) Yu Takahashi et al. PHARMACEUTICAL RESEARCH
- Sesamol Induces Human Hepatocellular Carcinoma Cells Apoptosis by Impairing Mitochondrial Function and Suppressing Autophagy
- (2017) Zhigang Liu et al. Scientific Reports
- Sesamol induced apoptotic effect in lung adenocarcinoma cells through both intrinsic and extrinsic pathways
- (2016) Boondaree Siriwarin et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Sesamol induces mitochondrial apoptosis pathway in HCT116 human colon cancer cells via pro-oxidant effect
- (2016) Munthipha Khamphio et al. LIFE SCIENCES
- Organic Carbamates in Drug Design and Medicinal Chemistry
- (2015) Arun K. Ghosh et al. JOURNAL OF MEDICINAL CHEMISTRY
- Prognostic significance of L-type amino acid transporter 1 (LAT1) expression in cutaneous melanoma
- (2015) Akira Shimizu et al. MELANOMA RESEARCH
- The Prodrug Approach: A Successful Tool for Improving Drug Solubility
- (2015) Daniela Jornada et al. MOLECULES
- Biopharmaceutical profiling of sesamol: physiochemical characterization, gastrointestinal permeability and pharmacokinetic evaluation
- (2015) T. Geetha et al. RSC Advances
- Targeting glutamine transport to suppress melanoma cell growth
- (2014) Qian Wang et al. INTERNATIONAL JOURNAL OF CANCER
- Sesamol-loaded solid lipid nanoparticles for treatment of skin cancer
- (2014) T. Geetha et al. JOURNAL OF DRUG TARGETING
- Application of FTIR microspectroscopy for characterization of biomolecular changes in human melanoma cells treated by sesamol and kojic acid
- (2013) Montra Srisayam et al. JOURNAL OF DERMATOLOGICAL SCIENCE
- Establishment of Stable Cell Lines With High Expression of Heterodimers of Human 4F2hc and Human Amino Acid Transporter LAT1 or LAT2 and Delineation of Their Differential Interaction With ^|^alpha;-Alkyl Moieties
- (2012) Narakorn Khunweeraphong et al. JOURNAL OF PHARMACOLOGICAL SCIENCES
- GLUT1 expression in malignant tumors and its use as an immunodiagnostic marker
- (2011) Kátia C. Carvalho et al. Clinics
- Qualitative structure-metabolism relationships in the hydrolysis of carbamates
- (2010) Federica Vacondio et al. DRUG METABOLISM REVIEWS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation