Degradation Mechanism of Autophagy-Related Proteins and Research Progress

Brassinosteroids (BRs) Role in Plant Development and Coping with Different Stresses

(2022) Hakim Manghwar et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Endoplasmic Reticulum Stress and Unfolded Protein Response Signaling in Plants

(2022) Hakim Manghwar et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

TRK-fused gene (TFG) regulates ULK1 stability via TRAF3-mediated ubiquitination and protects macrophages from LPS-induced pyroptosis

(2022) Jian-Hong Shi et al.   Cell Death & Disease

Plasmodium Circumsporozoite Protein Enhances the Efficacy of Gefitinib in Lung Adenocarcinoma Cells by Inhibiting Autophagy via Proteasomal Degradation of LC3B

(2022) Xiao Lu et al.   Frontiers in Cell and Developmental Biology

Advances, limitations, and prospects of biosensing technology for detecting phytopathogenic bacteria

(2022) Qurban Ali et al.   CHEMOSPHERE

A bacterial effector counteracts host autophagy by promoting degradation of an autophagy component

(2022) Jia Xuan Leong et al.   EMBO JOURNAL

Arabidopsis KCS5 and KCS6 Play Redundant Roles in Wax Synthesis

(2022) Haodong Huang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Genome Engineering Technology for Durable Disease Resistance: Recent Progress and Future Outlooks for Sustainable Agriculture

(2022) Qurban Ali et al.   Frontiers in Plant Science

The ATG4 protease integrates redox and stress signals to regulate autophagy

(2021) María Esther Pérez-Pérez et al.   JOURNAL OF EXPERIMENTAL BOTANY

VPS34 K29/K48 branched ubiquitination governed by UBE3C and TRABID regulates autophagy, proteostasis and liver metabolism

(2021) Yu-Hsuan Chen et al.   Nature Communications

CUL3 (cullin 3)-mediated ubiquitination and degradation of BECN1 (beclin 1) inhibit autophagy and promote tumor progression

(2021) Xuan Li et al.   Autophagy

Isolation and characterization of pathogen causing brown rot in lemon and its control by using ecofriendly botanicals

(2021) Fiza Liaquat et al.   PHYSIOLOGICAL AND MOLECULAR PLANT PATHOLOGY

Genome-wide comparative analysis of long-chain acyl-CoA synthetases (LACSs) gene family: A focus on identification, evolution and expression profiling related to lipid synthesis

(2021) Asma Ayaz et al.   PLANT PHYSIOLOGY AND BIOCHEMISTRY

PacBio Single-Molecule Long-Read Sequencing Reveals Genes Tolerating Manganese Stress in Schima superba Saplings

(2021) Fiza Liaquat et al.   Frontiers in Genetics

Mechanisms of Selective Autophagy

(2021) Trond Lamark et al.   Annual Review of Cell and Developmental Biology

ATG101 Degradation by HUWE1-Mediated Ubiquitination Impairs Autophagy and Reduces Survival in Cancer Cells

(2021) JaeYung Lee et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Molecular Cloning and Functional Analysis of GmLACS2-3 Reveals Its Involvement in Cutin and Suberin Biosynthesis along with Abiotic Stress Tolerance

(2021) Asma Ayaz et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Breakthroughs and bottlenecks in autophagy research

(2021) Noboru Mizushima et al.   TRENDS IN MOLECULAR MEDICINE

Plant Autophagy: An Intricate Process Controlled by Various Signaling Pathways

(2021) Pingping Wang et al.   Frontiers in Plant Science

Conserved and Diversified Mechanism of Autophagy between Plants and Animals upon Various Stresses

(2021) Naveed Ur Rehman et al.   Antioxidants

Autophagy and autophagy-related proteins in cancer

(2020) Xiaohua Li et al.   Molecular Cancer

Auto-ubiquitination of NEDD4-1 Recruits USP13 to Facilitate Autophagy through Deubiquitinating VPS34

(2020) Weihong Xie et al.   Cell Reports

Lysosome biology in autophagy

(2020) Willa Wen-You Yim et al.   Cell Discovery

Mechanisms governing autophagosome biogenesis

(2020) Hitoshi Nakatogawa   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Microautophagy in Plants: Consideration of Its Molecular Mechanism

(2020) Katarzyna Sieńko et al.   Cells

Streptococcus pneumoniae promotes its own survival via choline-binding protein CbpC-mediated degradation of ATG14

(2020) Sayaka Shizukuishi et al.   Autophagy

Multiple Functions of ATG8 Family Proteins in Plant Autophagy

(2020) Fan Bu et al.   Frontiers in Cell and Developmental Biology

AUTOPHAGY-RELATED14 And Its Associated Phosphatidylinositol 3-Kinase Complex Promotes Autophagy In Arabidopsis

(2020) Fen Liu et al.   PLANT CELL

Transcriptional and Epigenetic Regulation of Autophagy in Plants

(2020) Chao Yang et al.   TRENDS IN GENETICS

Interplay between the Ubiquitin Proteasome System and Ubiquitin-Mediated Autophagy in Plants

(2020) Tong Su et al.   Cells

MAPK1/3 kinase-dependent ULK1 degradation attenuates mitophagy and promotes breast cancer bone metastasis

(2020) Rong Deng et al.   Autophagy

The yeast mitophagy receptor Atg32 is ubiquitinated and degraded by the proteasome

(2020) Nadine Camougrand et al.   PLoS One

Downregulation of autophagy by Met30-mediated Atg9 ubiquitination

(2020) Yuchen Feng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gigaxonin E3 ligase governs ATG16L1 turnover to control autophagosome production

(2019) Aurora Scrivo et al.   Nature Communications

Multiple Regulatory Levels Shape Autophagy Activity in Plants

(2019) Mingkang Yang et al.   Frontiers in Plant Science

The immunoproteasome catalytic β5i subunit regulates cardiac hypertrophy by targeting the autophagy protein ATG5 for degradation

(2019) Xin Xie et al.   Science Advances

SIP/CacyBP promotes autophagy by regulating levels of BRUCE/Apollon, which stimulates LC3-I degradation

(2019) Tian-Xia Jiang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autophagy regulator Atg9 is degraded by the proteasome

(2019) Guohui Hu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Arabidopsis SINAT Proteins Control Autophagy by Mediating Ubiquitylation and Degradation of ATG13

(2019) Hua Qi et al.   PLANT CELL

Negative regulation of autophagy by UBA6-BIRC6–mediated ubiquitination of LC3

(2019) Rui Jia et al.   eLife

The ATG conjugation systems in autophagy

(2019) Noboru Mizushima   CURRENT OPINION IN CELL BIOLOGY

Autophagy: The Master of Bulk and Selective Recycling

(2018) Richard S. Marshall et al.   Annual Review of Plant Biology

Saturated fatty acid palmitate negatively regulates autophagy by promoting ATG5 protein degradation in meniscus cells

(2018) Aritra Mallik et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The deubiquitinating enzyme USP20 stabilizes ULK1 and promotes autophagy initiation

(2018) Jun Hwan Kim et al.   EMBO REPORTS

A brief history of autophagy from cell biology to physiology and disease

(2018) Noboru Mizushima   NATURE CELL BIOLOGY

Mechanism and medical implications of mammalian autophagy

(2018) Ivan Dikic et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Expression analysis of defense related genes in wheat and maize against Bipolaris sorokiniana

(2018) Hakim Manghwar et al.   PHYSIOLOGICAL AND MOLECULAR PLANT PATHOLOGY

Multiscale and Multimodal Approaches to Study Autophagy in Model Plants

(2018) Jessica Marion et al.   Cells

TRIM59 regulates autophagy through modulating both the transcription and the ubiquitination of BECN1

(2018) Tianyu Han et al.   Autophagy

A regulatory role of autophagy for resetting the memory of heat stress in plants

(2018) Mastoureh Sedaghatmehr et al.   PLANT CELL AND ENVIRONMENT

mTORC1-Regulated and HUWE1-Mediated WIPI2 Degradation Controls Autophagy Flux

(2018) Wei Wan et al.   MOLECULAR CELL

Ubiquitination of the PI3-kinase VPS-34 promotes VPS-34 stability and phagosome maturation

(2017) Jinchao Liu et al.   JOURNAL OF CELL BIOLOGY

Modulation of plant autophagy during pathogen attack

(2017) Alexandre Y Leary et al.   JOURNAL OF EXPERIMENTAL BOTANY

The ER-Localized Transmembrane Protein EPG-3/VMP1 Regulates SERCA Activity to Control ER-Isolation Membrane Contacts for Autophagosome Formation

(2017) Yan G. Zhao et al.   MOLECULAR CELL

TRAF Family Proteins Regulate Autophagy Dynamics by Modulating AUTOPHAGY PROTEIN6 Stability in Arabidopsis

(2017) Hua Qi et al.   PLANT CELL

Oh, the places they'll go! A survey of phytopathogen effectors and their host targets

(2017) Madiha Khan et al.   PLANT JOURNAL

ATG9 regulates autophagosome progression from the endoplasmic reticulum inArabidopsis

(2017) Xiaohong Zhuang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Ubiquitin Code in the Ubiquitin-Proteasome System and Autophagy

(2017) Yong Tae Kwon et al.   TRENDS IN BIOCHEMICAL SCIENCES

Modeling of autophagy-related gene expression dynamics during long term fasting in European eel (Anguilla anguilla)

(2017) Valérie Bolliet et al.   Scientific Reports

Autophagy Is Rapidly Induced by Salt Stress and Is Required for Salt Tolerance in Arabidopsis

(2017) Liming Luo et al.   Frontiers in Plant Science

Multifaceted Housekeeping Functions of Autophagy

(2017) Sarika Chinchwadkar et al.   JOURNAL OF THE INDIAN INSTITUTE OF SCIENCE

AMPK regulates autophagy by phosphorylating BECN1 at threonine 388

(2016) Deyi Zhang et al.   Autophagy

Recruitment of TBK1 to cytosol‐invading Salmonella induces WIPI2‐dependent antibacterial autophagy

(2016) Teresa LM Thurston et al.   EMBO JOURNAL

USP19 modulates autophagy and antiviral immune responses by deubiquitinating Beclin‐1

(2016) Shouheng Jin et al.   EMBO JOURNAL

To deliver or to degrade - an interplay of the ubiquitin-proteasome system, autophagy and vesicular transport in plants

(2016) Katarzyna Zientara-Rytter et al.   FEBS Journal

Spodoptera lituraautophagy-related protein 1 interacts with autophagy-related protein 5 and enhances its degradation

(2016) N. Zhang et al.   INSECT MOLECULAR BIOLOGY

Fine-tuning of ULK1 mRNA and protein levels is required for autophagy oscillation

(2016) Francesca Nazio et al.   JOURNAL OF CELL BIOLOGY

Cul3-KLHL20 Ubiquitin Ligase Governs the Turnover of ULK1 and VPS34 Complexes to Control Autophagy Termination

(2016) Chin-Chih Liu et al.   MOLECULAR CELL

The Degradation Pathway of the Mitophagy Receptor Atg32 Is Re-Routed by a Posttranslational Modification

(2016) Mariia Levchenko et al.   PLoS One

In vivo aspects of protein folding and quality control

(2016) D. Balchin et al.   SCIENCE

SLC9A3R1 stimulates autophagy via BECN1 stabilization in breast cancer cells

(2015) Hong Liu et al.   Autophagy

Tomato HsfA1a plays a critical role in plant drought tolerance by activatingATGgenes and inducing autophagy

(2015) Yu Wang et al.   Autophagy

FBXL20-mediated Vps34 ubiquitination as a p53 controlled checkpoint in regulating autophagy and receptor degradation

(2015) Juan Xiao et al.   GENES & DEVELOPMENT

Autophagic Recycling Plays a Central Role in Maize Nitrogen Remobilization

(2015) Faqiang Li et al.   PLANT CELL

UPR, autophagy, and mitochondria crosstalk underlies the ER stress response

(2015) Daniela Senft et al.   TRENDS IN BIOCHEMICAL SCIENCES

How to control self-digestion: transcriptional, post-transcriptional, and post-translational regulation of autophagy

(2015) Yuchen Feng et al.   TRENDS IN CELL BIOLOGY

G-protein-coupled receptors regulate autophagy by ZBTB16-mediated ubiquitination and proteasomal degradation of Atg14L

(2015) Tao Zhang et al.   eLife

Ubiquitination and proteasomal degradation of ATG12 regulates its proapoptotic activity

(2015) Martina Haller et al.   Autophagy

Autophagosome biogenesis in plants

(2014) Xiaohong Zhuang et al.   Autophagy

Regulation of autophagy by E3 ubiquitin ligase RNF216 through BECN1 ubiquitination

(2014) Congfeng Xu et al.   Autophagy

Autosis and autophagic cell death: the dark side of autophagy

(2014) Y Liu et al.   CELL DEATH AND DIFFERENTIATION

Transcriptional Regulation by Pho23 Modulates the Frequency of Autophagosome Formation

(2014) Meiyan Jin et al.   CURRENT BIOLOGY

ULK1 translocates to mitochondria and phosphorylates FUNDC1 to regulate mitophagy

(2014) W. Wu et al.   EMBO REPORTS

AUTOPHAGY-RELATED11 Plays a Critical Role in General Autophagy- and Senescence-Induced Mitophagy in Arabidopsis

(2014) F. Li et al.   PLANT CELL

Ultrastructure of autophagy in plant cells

(2013) Wouter G van Doorn et al.   Autophagy

The role of autophagy in neurodegenerative disease

(2013) Ralph A Nixon   NATURE MEDICINE

Mechanisms and function of substrate recruitment by F-box proteins

(2013) Jeffrey R. Skaar et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The tumor necrosis factor receptor-associated factor (TRAF)-like family protein SEVEN IN ABSENTIA 2 (SINA2) promotes drought tolerance in an ABA-dependent manner in Arabidopsis

(2013) Yan Bao et al.   NEW PHYTOLOGIST

Advanced Proteomic Analyses Yield a Deep Catalog of Ubiquitylation Targets inArabidopsis

(2013) Do-Young Kim et al.   PLANT CELL

Structural basis of ATG3 recognition by the autophagic ubiquitin-like protein ATG12

(2013) Z. Metlagel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ubiquitin-Like Proteins

(2012) Annemarthe G. van der Veen et al.   Annual Review of Biochemistry

Autophagy: Pathways for Self-Eating in Plant Cells

(2012) Yimo Liu et al.   Annual Review of Plant Biology

Mitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cells

(2012) Lei Liu et al.   NATURE CELL BIOLOGY

Nedd4-dependent lysine-11-linked polyubiquitination of the tumour suppressor Beclin 1

(2011) Harald W. Platta et al.   BIOCHEMICAL JOURNAL

Beclin1 Controls the Levels of p53 by Regulating the Deubiquitination Activity of USP10 and USP13

(2011) Junli Liu et al.   CELL

The Beclin 1 network regulates autophagy and apoptosis

(2011) R Kang et al.   CELL DEATH AND DIFFERENTIATION

Autophagy as an innate immunity paradigm: expanding the scope and repertoire of pattern recognition receptors

(2011) Vojo Deretic   CURRENT OPINION IN IMMUNOLOGY

The ATG1/ATG13 Protein Kinase Complex Is Both a Regulator and a Target of Autophagic Recycling in Arabidopsis

(2011) A. Suttangkakul et al.   PLANT CELL

Autophagy Protein Atg3 is Essential for Maintaining Mitochondrial Integrity and for Normal Intracellular Development of Toxoplasma gondii Tachyzoites

(2011) Sébastien Besteiro et al.   PLoS Pathogens

Roles of the Lipid-binding Motifs of Atg18 and Atg21 in the Cytoplasm to Vacuole Targeting Pathway and Autophagy

(2010) Usha Nair et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Overexpression of Arabidopsis Acyl-CoA Binding Protein ACBP3 Promotes Starvation-Induced and Age-Dependent Leaf Senescence

(2010) S. Xiao et al.   PLANT CELL

ATG8 lipidation and ATG8-mediated autophagy in Arabidopsis require ATG12 expressed from the differentially controlled ATG12A AND ATG12B loci

(2010) Taijoon Chung et al.   PLANT JOURNAL

Autophagy and Metabolism

(2010) J. D. Rabinowitz et al.   SCIENCE

TRAF6 and A20 Regulate Lysine 63-Linked Ubiquitination of Beclin-1 to Control TLR4-Induced Autophagy

(2010) C. S. Shi et al.   Science Signaling

The Beclin 1–VPS34 complex – at the crossroads of autophagy and beyond

(2010) Sarah F. Funderburk et al.   TRENDS IN CELL BIOLOGY

A novel, human Atg13 binding protein, Atg101, interacts with ULK1 and is essential for macroautophagy

(2009) Carol A. Mercer et al.   Autophagy

Atg101, a novel mammalian autophagy protein interacting with Atg13

(2009) Nao Hosokawa et al.   Autophagy

Atg32 Is a Mitochondrial Protein that Confers Selectivity during Mitophagy

(2009) Tomotake Kanki et al.   DEVELOPMENTAL CELL

Nutrient-dependent mTORC1 Association with the ULK1–Atg13–FIP200 Complex Required for Autophagy

(2009) Nao Hosokawa et al.   MOLECULAR BIOLOGY OF THE CELL

Autophagy and the ubiquitin-proteasome system: Collaborators in neuroprotection

(2008) Natalia B. Nedelsky et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE