标题
Varicella‐Zoster virus ORF9 is an antagonist of the DNA sensor cGAS
作者
关键词
-
出版物
EMBO JOURNAL
Volume 41, Issue 14, Pages -
出版商
EMBO
发表日期
2022-06-07
DOI
10.15252/embj.2021109217
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- cGAS phase separation inhibits TREX1-mediated DNA degradation and enhances cytosolic DNA sensing
- (2021) Wen Zhou et al. MOLECULAR CELL
- Viral tegument proteins restrict cGAS-DNA phase separation to mediate immune evasion
- (2021) Guangjun Xu et al. MOLECULAR CELL
- Varicella-zoster virus early infection but not complete replication is required for the induction of chronic hypersensitivity in rat models of postherpetic neuralgia
- (2021) Benjamin E. Warner et al. PLoS Pathogens
- Manipulation of the Innate Immune Response by Varicella Zoster Virus
- (2020) Chelsea Gerada et al. Frontiers in Immunology
- Molecular mechanisms and cellular functions of cGAS–STING signalling
- (2020) Karl-Peter Hopfner et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- cGAS in action: Expanding roles in immunity and inflammation
- (2019) Andrea Ablasser et al. SCIENCE
- Coevolution pays off: Herpesviruses have the license to escape the DNA sensing pathway
- (2019) Markus Stempel et al. MEDICAL MICROBIOLOGY AND IMMUNOLOGY
- Interferon Gamma Inhibits Varicella-Zoster Virus Replication in a Cell Line-Dependent Manner
- (2019) Akhalesh K. Shakya et al. JOURNAL OF VIROLOGY
- The PSIPRED Protein Analysis Workbench: 20 years on
- (2019) Daniel W A Buchan et al. NUCLEIC ACIDS RESEARCH
- Human cGAS catalytic domain has an additional DNA-binding interface that enhances enzymatic activity and liquid-phase condensation
- (2019) Wei Xie et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- HSV-1 single cell analysis reveals anti-viral and developmental programs activation in distinct sub-populations
- (2019) Nir Drayman et al. eLife
- Interferon-Stimulated Genes: What Do They All Do?
- (2019) John W. Schoggins Annual Review of Virology
- Nucleic Acid Sensors and Programmed Cell Death
- (2019) Jonathan Maelfait et al. JOURNAL OF MOLECULAR BIOLOGY
- PKR-dependent cytosolic cGAS foci are necessary for intracellular DNA sensing
- (2019) Siqi Hu et al. Science Signaling
- Structure of the Human cGAS–DNA Complex Reveals Enhanced Control of Immune Surveillance
- (2018) Wen Zhou et al. CELL
- Infection with a Brazilian isolate of Zika virus generates RIG-I stimulatory RNA and the viral NS5 protein blocks type I IFN induction and signaling
- (2018) Jonny Hertzog et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Herpes Simplex Virus 1 Tegument Protein VP22 Abrogates cGAS/STING-Mediated Antiviral Innate Immunity
- (2018) Jian Huang et al. JOURNAL OF VIROLOGY
- Varicella-Zoster Virus ORF9p Binding to Cellular Adaptor Protein Complex 1 Is Important for Viral Infectivity
- (2018) Marielle Lebrun et al. JOURNAL OF VIROLOGY
- DNA-induced liquid phase condensation of cGAS activates innate immune signaling
- (2018) Mingjian Du et al. SCIENCE
- Varicella zoster virus productively infects human natural killer cells and manipulates phenotype
- (2018) Tessa Mollie Campbell et al. PLoS Pathogens
- RNA Polymerase III as a Gatekeeper to Prevent Severe VZV Infections
- (2018) Madalina E. Carter-Timofte et al. TRENDS IN MOLECULAR MEDICINE
- Infection and Functional Modulation of Human Monocytes and Macrophages by Varicella-Zoster Virus
- (2018) Jarrod J. Kennedy et al. JOURNAL OF VIROLOGY
- Design of amidobenzimidazole STING receptor agonists with systemic activity
- (2018) Joshi M. Ramanjulu et al. NATURE
- Interactome and Proteome Dynamics Uncover Immune Modulatory Associations of the Pathogen Sensing Factor cGAS
- (2018) Krystal K. Lum et al. Cell Systems
- STING Is Involved in Antiviral Immune Response against VZV Infection via the Induction of Type I and III IFN Pathways
- (2017) Ji-Ae Kim et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- cGAS surveillance of micronuclei links genome instability to innate immunity
- (2017) Karen J. Mackenzie et al. NATURE
- Mitotic progression following DNA damage enables pattern recognition within micronuclei
- (2017) Shane M. Harding et al. NATURE
- cGAS senses long and HMGB/TFAM-bound U-turn DNA by forming protein–DNA ladders
- (2017) Liudmila Andreeva et al. NATURE
- IFI16 and cGAS cooperate in the activation of STING during DNA sensing in human keratinocytes
- (2017) Jessica F. Almine et al. Nature Communications
- Importance of Nucleic Acid Recognition in Inflammation and Autoimmunity
- (2016) Franck J. Barrat et al. Annual Review of Medicine
- Kaposi's Sarcoma-Associated Herpesvirus Inhibitor of cGAS (KicGAS), Encoded by ORF52, Is an Abundant Tegument Protein and Is Required for Production of Infectious Progeny Viruses
- (2016) Wenwei Li et al. JOURNAL OF VIROLOGY
- Influenza A virus targets a cGAS-independent STING pathway that controls enveloped RNA viruses
- (2016) Christian K. Holm et al. Nature Communications
- Type I interferon inhibits varicella-zoster virus replication by interfering with the dynamic interaction between mediator and IE62 within replication compartments
- (2016) Chia-Chi Ku et al. Cell and Bioscience
- Innate Immune Pattern Recognition: A Cell Biological Perspective
- (2015) Sky W. Brubaker et al. Annual Review of Immunology
- Inhibition of cGAS DNA Sensing by a Herpesvirus Virion Protein
- (2015) Jian-jun Wu et al. Cell Host & Microbe
- VP22 core domain from Herpes simplex virus 1 reveals a surprising structural conservation in both the Alpha- and Gammaherpesvirinae subfamilies
- (2015) Kelly Hew et al. JOURNAL OF GENERAL VIROLOGY
- Ancient Origin of cGAS-STING Reveals Mechanism of Universal 2′,3′ cGAMP Signaling
- (2015) Philip J. Kranzusch et al. MOLECULAR CELL
- Mitochondrial DNA stress primes the antiviral innate immune response
- (2015) A. Phillip West et al. NATURE
- Viruses transfer the antiviral second messenger cGAMP between cells
- (2015) A. Bridgeman et al. SCIENCE
- Neurological complications of varicella zoster virus reactivation
- (2014) Maria A. Nagel et al. CURRENT OPINION IN NEUROLOGY
- Deletion of the ORF9p Acidic Cluster Impairs the Nuclear Egress of Varicella-Zoster Virus Capsids
- (2014) Laura Riva et al. JOURNAL OF VIROLOGY
- Molecular mechanisms of varicella zoster virus pathogenesis
- (2014) Leigh Zerboni et al. NATURE REVIEWS MICROBIOLOGY
- PredictProtein—an open resource for online prediction of protein structural and functional features
- (2014) Guy Yachdav et al. NUCLEIC ACIDS RESEARCH
- Easy quantitative assessment of genome editing by sequence trace decomposition
- (2014) Eva K. Brinkman et al. NUCLEIC ACIDS RESEARCH
- The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop
- (2014) Xu Zhang et al. Cell Reports
- Cyclic GMP-AMP Synthase Is Activated by Double-Stranded DNA-Induced Oligomerization
- (2013) Xin Li et al. IMMUNITY
- Proteasomal Degradation of Herpes Simplex Virus Capsids in Macrophages Releases DNA to the Cytosol for Recognition by DNA Sensors
- (2013) K. A. Horan et al. JOURNAL OF IMMUNOLOGY
- ORF11 Protein Interacts with the ORF9 Essential Tegument Protein in Varicella-Zoster Virus Infection
- (2013) X. Che et al. JOURNAL OF VIROLOGY
- Structure of Human cGAS Reveals a Conserved Family of Second-Messenger Enzymes in Innate Immunity
- (2013) Philip J. Kranzusch et al. Cell Reports
- ORF9p Phosphorylation by ORF47p Is Crucial for the Formation and Egress of Varicella-Zoster Virus Viral Particles
- (2012) L. Riva et al. JOURNAL OF VIROLOGY
- Fiji: an open-source platform for biological-image analysis
- (2012) Johannes Schindelin et al. NATURE METHODS
- Cyclic GMP-AMP Is an Endogenous Second Messenger in Innate Immune Signaling by Cytosolic DNA
- (2012) J. Wu et al. SCIENCE
- Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway
- (2012) L. Sun et al. SCIENCE
- IFN-α production by human mononuclear cells infected with varicella-zoster virus through TLR9-dependent and -independent pathways
- (2011) Hong-Ren Yu et al. Cellular & Molecular Immunology
- Varicella-Zoster Virus Infection Triggers Formation of an Interleukin-1β (IL-1β)-processing Inflammasome Complex
- (2011) Adel M. Nour et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Varicella-Zoster Virus Immediate-Early Protein ORF61 Abrogates the IRF3-Mediated Innate Immune Response through Degradation of Activated IRF3
- (2011) H. Zhu et al. JOURNAL OF VIROLOGY
- RIG-I Detects Viral Genomic RNA during Negative-Strand RNA Virus Infection
- (2010) Jan Rehwinkel et al. CELL
- Varicella-Zoster Virus Immediate-Early Protein 62 Blocks Interferon Regulatory Factor 3 (IRF3) Phosphorylation at Key Serine Residues: a Novel Mechanism of IRF3 Inhibition among Herpesviruses
- (2010) N. Sen et al. JOURNAL OF VIROLOGY
- IFI16 is an innate immune sensor for intracellular DNA
- (2010) Leonie Unterholzner et al. NATURE IMMUNOLOGY
- Functions of the ORF9-to-ORF12 Gene Cluster in Varicella-Zoster Virus Replication and in the Pathogenesis of Skin Infection
- (2008) X. Che et al. JOURNAL OF VIROLOGY
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