Molecular insights into human taste perception and umami tastants: A review

Xerostomia and hyposalivation among a 65‐yr‐old population living in Oslo, Norway

(2021) My Tien Diep et al.   EUROPEAN JOURNAL OF ORAL SCIENCES

Polymorphic variants in Sweet and Umami taste receptor genes and birthweight

(2021) Riccardo Farinella et al.   Scientific Reports

Mechanisms of umami taste perception: From molecular level to brain imaging

(2021) Ben Wu et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Can umami taste be an adequate tool for reducing sodium in food preparations?

(2021) Mariana Simões do Couto Rosa et al.   INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY

Molecular and cellular basis of acid taste sensation in Drosophila

(2021) Tingwei Mi et al.   Nature Communications

Extraction and analysis of free amino acids and 5′-nucleotides, the key contributors to the umami taste of seaweed

(2021) Tanja C.W. Moerdijk-Poortvliet et al.   FOOD CHEMISTRY

Taste Bud Connectome: Implications for Taste Information Processing

(2021) Courtney E. Wilson et al.   JOURNAL OF NEUROSCIENCE

Quantitative verification of the effect of using an umami substance (L-glutamate) to reduce salt intake

(2020) Rieko Morita et al.   HYPERTENSION RESEARCH

Does ENaC Work as Sodium Taste Receptor in Humans?

(2020) Albertino Bigiani   Nutrients

Single nucleotide polymorphisms in sweet, fat, umami, salt, bitter and sour taste receptor genes are associated with gustatory function and taste preferences in young adults

(2020) Elie Chamoun et al.   NUTRITION RESEARCH

Isolation, characterization and molecular docking of novel umami and umami-enhancing peptides from Ruditapes philippinarum

(2020) Yue Zhang et al.   FOOD CHEMISTRY

Food in the Anthropocene: the EAT–Lancet Commission on healthy diets from sustainable food systems

(2019) Walter Willett et al.   LANCET

Taste Receptors: New Players in Sperm Biology

(2019) Alice Luddi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Recognizing Taste: Coding Patterns Along the Neural Axis in Mammals

(2019) Kathrin Ohla et al.   CHEMICAL SENSES

New insight into human sweet taste: a genome-wide association study of the perception and intake of sweet substances

(2019) Liang-Dar Hwang et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

The Science of Salt: Updating the evidence on global estimates of salt intake

(2019) Sudhir Raj Thout et al.   Journal of Clinical Hypertension

Understanding the molecular mechanism of umami recognition by T1R1-T1R3 using molecular dynamics simulations

(2019) Hai Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Identification of a novel umami compound in potatoes and potato chips

(2018) Liyun Zhang et al.   FOOD CHEMISTRY

An evolutionarily conserved gene family encodes proton-selective ion channels

(2018) Yu-Hsiang Tu et al.   SCIENCE

Chemical synapses without synaptic vesicles: Purinergic neurotransmission through a CALHM1 channel-mitochondrial signaling complex

(2018) Roman A. Romanov et al.   Science Signaling

Chemical synapses without synaptic vesicles: Purinergic neurotransmission through a CALHM1 channel-mitochondrial signaling complex

(2018) Roman A. Romanov et al.   Science Signaling

Molecular docking and simulation of the synergistic effect between umami peptides, monosodium glutamate and taste receptor T1R1/T1R3

(2018) Yali Dang et al.   FOOD CHEMISTRY

Insight in taste alterations during treatment with protein kinase inhibitors

(2017) A. van der Werf et al.   EUROPEAN JOURNAL OF CANCER

The structure features of umami hexapeptides for the T1R1/T1R3 receptor

(2017) Xiaqin Yu et al.   FOOD CHEMISTRY

Human Biology of Taste

(2017) Stephen A. Gravina et al.   ANNALS OF SAUDI MEDICINE

Formation of taste-active amino acids, amino acid derivatives and peptides in food fermentations – A review

(2016) Cindy J. Zhao et al.   FOOD RESEARCH INTERNATIONAL

Novel Umami Ingredients: Umami Peptides and Their Taste

(2016) Yin Zhang et al.   JOURNAL OF FOOD SCIENCE

Metabotropic glutamate receptors are involved in the detection of IMP and l -amino acids by mouse taste sensory cells

(2016) S. Pal Choudhuri et al.   NEUROSCIENCE

Characterizing hydrophobicity of amino acid side chains in a protein environment via measuring contact angle of a water nanodroplet on planar peptide network

(2016) Chongqin Zhu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In vitro expression and analysis of the 826 human G protein-coupled receptors

(2016) Xuechen Lv et al.   Protein & Cell

Umami–bitter interactions: The suppression of bitterness by umami peptides via human bitter taste receptor

(2015) Min Jung Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Monosodium l-glutamate in soup reduces subsequent energy intake from high-fat savoury food in overweight and obese women

(2015) Takashi Miyaki et al.   BRITISH JOURNAL OF NUTRITION

Involvement of multiple taste receptors in umami taste: analysis of gustatory nerve responses in metabotropic glutamate receptor 4 knockout mice

(2015) Keiko Yasumatsu et al.   JOURNAL OF PHYSIOLOGY-LONDON

Comparison of umami taste peptides in water-soluble extractions of Jinhua and Parma hams

(2015) Yali Dang et al.   LWT-FOOD SCIENCE AND TECHNOLOGY

The K+channel KIR2.1 functions in tandem with proton influx to mediate sour taste transduction

(2015) Wenlei Ye et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Breadth of tuning in taste afferent neurons varies with stimulus strength

(2015) An Wu et al.   Nature Communications

Umami the Fifth Basic Taste: History of Studies on Receptor Mechanisms and Role as a Food Flavor

(2015) Kenzo Kurihara   Biomed Research International

Supplementing chicken broth with monosodium glutamate reduces energy intake from high fat and sweet snacks in middle-aged healthy women

(2014) Toshifumi Imada et al.   APPETITE

Umami flavor enhances appetite but also increases satiety

(2014) Una Masic et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Peripheral Coding of Taste

(2014) Emily R. Liman et al.   NEURON

The bitter pill: clinical drugs that activate the human bitter taste receptor TAS2R14

(2013) Anat Levit et al.   FASEB JOURNAL

The Human Bitter Taste Receptor TAS2R10 Is Tailored to Accommodate Numerous Diverse Ligands

(2013) S. Born et al.   JOURNAL OF NEUROSCIENCE

Minireview: Nutrient Sensing by G Protein-Coupled Receptors

(2013) Eric M. Wauson et al.   MOLECULAR ENDOCRINOLOGY

High salt recruits aversive taste pathways

(2013) Yuki Oka et al.   NATURE

Evolution of phototransduction, vertebrate photoreceptors and retina

(2013) Trevor D. Lamb   PROGRESS IN RETINAL AND EYE RESEARCH

Recent developments on umami ingredients of edible mushrooms – A review

(2013) Yin Zhang et al.   TRENDS IN FOOD SCIENCE & TECHNOLOGY

Gustatory sensation of l- and d-amino acids in humans

(2012) Misako Kawai et al.   AMINO ACIDS

Probing Heterotrimeric G Protein Activation: Applications to Biased Ligands

(2012) Colette Denis et al.   CURRENT PHARMACEUTICAL DESIGN

Molecular mechanism of the allosteric enhancement of the umami taste sensation

(2012) Ole G. Mouritsen et al.   FEBS Journal

Isolation and identification of two novel umami and umami-enhancing peptides from peanut hydrolysate by consecutive chromatography and MALDI-TOF/TOF MS

(2012) Guowan Su et al.   FOOD CHEMISTRY

Isolation and Identification of the Umami Enhancing Compounds in Japanese Soy Sauce

(2011) Shu KANEKO et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Structural Basis of Activation of Bitter Taste Receptor T2R1 and Comparison with Class A G-protein-coupled Receptors (GPCRs)

(2011) Nisha Singh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Determinants of sweetness in proteins: a topological approach

(2011) Piero Andrea Temussi   JOURNAL OF MOLECULAR RECOGNITION

The role of G protein-coupled receptors in the pathology of Alzheimer's disease

(2011) Amantha Thathiah et al.   NATURE REVIEWS NEUROSCIENCE

The functional role of the T1R family of receptors in sweet taste and feeding

(2011) Yada Treesukosol et al.   PHYSIOLOGY & BEHAVIOR

Sour Taste Responses in Mice Lacking PKD Channels

(2011) Nao Horio et al.   PLoS One

A Gustotopic Map of Taste Qualities in the Mammalian Brain

(2011) X. Chen et al.   SCIENCE

Oligomerization of TAS2R Bitter Taste Receptors

(2010) Christina Kuhn et al.   CHEMICAL SENSES

Diabetes area participation analysis: a review of companies and targets described in the 2008 – 2010 patent literature

(2010) Philip A Carpino et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Characterization of the β-d-Glucopyranoside Binding Site of the Human Bitter Taste Receptor hTAS2R16

(2010) Takanobu Sakurai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The cells and peripheral representation of sodium taste in mice

(2010) Jayaram Chandrashekar et al.   NATURE

A proton current drives action potentials in genetically identified sour taste cells

(2010) R. B. Chang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural requirements of bitter taste receptor activation

(2010) A. Brockhoff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Taste receptors for umami: the case for multiple receptors

(2009) Nirupa Chaudhari et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Kokumi-Active Glutamyl Peptides in Cheeses and Their Biogeneration by Penicillium roquefortii

(2009) Simone Toelstede et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

A Series of Kokumi Peptides Impart the Long-Lasting Mouthfulness of Matured Gouda Cheese

(2009) Simone Toelstede et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

The Taste of Carbonation

(2009) J. Chandrashekar et al.   SCIENCE

Autoimmune mediated G-protein receptor activation in cardiovascular and renal pathologies

(2009) Duska Dragun et al.   THROMBOSIS AND HAEMOSTASIS

Quantitative Studies and Taste Re-engineering Experiments toward the Decoding of the Nonvolatile Sensometabolome of Gouda Cheese

(2008) Simone Toelstede et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Molecular mechanism for the umami taste synergism

(2008) F. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA