标题
Advanced drug delivery system against ischemic stroke
作者
关键词
Ischemic stroke, Drug delivery system, Thrombolysis, Blood brain barriers, Neuroprotection
出版物
JOURNAL OF CONTROLLED RELEASE
Volume 344, Issue -, Pages 173-201
出版商
Elsevier BV
发表日期
2022-03-04
DOI
10.1016/j.jconrel.2022.02.036
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Bioresponsive Polyphenol-Based Nanoparticles as Thrombolytic Drug Carriers
- (2022) Haitao Yu et al. ACS Applied Materials & Interfaces
- Neutrophil-like Cell-Membrane-Coated Nanozyme Therapy for Ischemic Brain Damage and Long-Term Neurological Functional Recovery
- (2021) Lishuai Feng et al. ACS Nano
- Preferential Targeting Cerebral Ischemic Lesions with Cancer Cell-Inspired Nanovehicle for Ischemic Stroke Treatment
- (2021) Wenxiu He et al. NANO LETTERS
- Surface-modified engineered exosomes attenuated cerebral ischemia/reperfusion injury by targeting the delivery of quercetin towards impaired neurons
- (2021) Lin Guo et al. JOURNAL OF NANOBIOTECHNOLOGY
- Thrombus-specific theranostic nanocomposite for codelivery of thrombolytic drug, algae-derived anticoagulant and NIR fluorescent contrast agent
- (2021) Lee-Hsin Chang et al. Acta Biomaterialia
- Thrombus-targeted nanoparticles for thrombin-triggered thrombolysis and local inflammatory microenvironment regulation
- (2021) Huijuan Zhang et al. JOURNAL OF CONTROLLED RELEASE
- Magneto-sonothrombolysis with combination of magnetic microbubbles and nanodroplets
- (2021) Bohua Zhang et al. ULTRASONICS
- pH‐Sensitive, Cerebral Vasculature‐Targeting Hydroxyethyl Starch Functionalized Nanoparticles for Improved Angiogenesis and Neurological Function Recovery in Ischemic Stroke
- (2021) Hang Yang et al. Advanced Healthcare Materials
- Fibrinogen-mimicking, multiarm nanovesicles for human thrombus-specific delivery of tissue plasminogen activator and targeted thrombolytic therapy
- (2021) Yu Huang et al. Science Advances
- Ultrasound-Propelled Janus Rod-Shaped Micromotors for Site-Specific Sonodynamic Thrombolysis
- (2021) Wenxiong Cao et al. ACS Applied Materials & Interfaces
- Fucoidan-functionalized polysaccharide submicroparticles loaded with alteplase for efficient targeted thrombolytic therapy
- (2021) Alina Zenych et al. BIOMATERIALS
- A stepwise-targeting strategy for the treatment of cerebral ischemic stroke
- (2021) Jingbo Hu et al. JOURNAL OF NANOBIOTECHNOLOGY
- Elaborately Engineering a Self‐Indicating Dual‐Drug Nanoassembly for Site‐Specific Photothermal‐Potentiated Thrombus Penetration and Thrombolysis
- (2021) Zhiqiang Zhao et al. Advanced Science
- Rescuing ischemic stroke by biomimetic nanovesicles through accelerated thrombolysis and sequential ischemia-reperfusion protection
- (2021) Wenyan Yu et al. Acta Biomaterialia
- Nitric oxide-driven nanomotors with bowl-shaped mesoporous silica for targeted thrombolysis
- (2021) Yingfang Tao et al. JOURNAL OF COLLOID AND INTERFACE SCIENCE
- Modulation of Microglia Polarization through Silencing of NF-κB p65 by Functionalized Curdlan Nanoparticle-Mediated RNAi
- (2020) Tsogzolmaa Ganbold et al. ACS Applied Materials & Interfaces
- Platelet Membrane Biomimetic Magnetic Nanocarriers for Targeted Delivery and in Situ Generation of Nitric Oxide in Early Ischemic Stroke
- (2020) Mingxi Li et al. ACS Nano
- Mesenchymal stem cell-derived magnetic extracellular nanovesicles for targeting and treatment of ischemic stroke
- (2020) Han Young Kim et al. BIOMATERIALS
- Liposomal 9-Aminoacridine for Treatment of Ischemic Stroke: From Drug Discovery to Drug Delivery
- (2020) Haojie Wang et al. NANO LETTERS
- Cxcr4 distinguishes HSC-derived monocytes from microglia and reveals monocyte immune responses to experimental stroke
- (2020) Yves Werner et al. NATURE NEUROSCIENCE
- Intrinsic Biotaxi Solution Based on Blood Cell Membrane Cloaking Enables Fullerenol Thrombolysis In Vivo
- (2020) Kui Chen et al. ACS Applied Materials & Interfaces
- EMMPRIN/CD147 plays a detrimental role in clinical and experimental ischemic stroke
- (2020) Anthony Patrizz et al. Aging-US
- Preparation of Peptide and Recombinant Tissue Plasminogen Activator Conjugated Poly(Lactic-Co-Glycolic Acid) (PLGA) Magnetic Nanoparticles for Dual Targeted Thrombolytic Therapy
- (2020) Huai-An Chen et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- EWVDV-Mediated Platelet-Targeting Nanoparticles for the Multimodal Imaging of Thrombi at Different Blood Flow Velocities
- (2020) Jie Xu et al. International Journal of Nanomedicine
- Mechanisms in blood-brain barrier opening and metabolism-challenged cerebrovascular ischemia with emphasis on ischemic stroke
- (2020) Sajad Sarvari et al. METABOLIC BRAIN DISEASE
- Cell Death Pathways in Ischemic Stroke and Targeted Pharmacotherapy
- (2020) Aishika Datta et al. Translational Stroke Research
- Platelet-derived porous nanomotor for thrombus therapy
- (2020) Mimi Wan et al. Science Advances
- Biomaterials to Neuroprotect the Stroke Brain: A Large Opportunity for Narrow Time Windows
- (2020) Daniel González-Nieto et al. Cells
- Conopeptide-Functionalized Nanoparticles Selectively Antagonize Extrasynaptic N-Methyl-d-aspartate Receptors and Protect Hippocampal Neurons from Excitotoxicity In Vitro
- (2020) Pierluigi Valente et al. ACS Nano
- Edaravone-Loaded Macrophage-Derived Exosomes Enhance Neuroprotection in the Rat Permanent Middle Cerebral Artery Occlusion Model of Stroke
- (2020) Fang Li et al. MOLECULAR PHARMACEUTICS
- Glycoprotein VI (GPVI)-functionalized nanoparticles targeting arterial injury sites under physiological flow
- (2020) Moran Levi et al. Nanomedicine-Nanotechnology Biology and Medicine
- Accelerating thrombolysis using a precision and clot-penetrating drug delivery strategy by nanoparticle-shelled microbubbles
- (2020) Siyu Wang et al. Science Advances
- Engineering Stem Cell Derived Biomimetic Vesicles for Versatility and Effective Targeted Delivery
- (2020) Honghui Wu et al. ADVANCED FUNCTIONAL MATERIALS
- The role of peripheral monocytes and macrophages in ischemic stroke
- (2020) Dong Han et al. NEUROLOGICAL SCIENCES
- Therapeutic Effects of Simultaneous Delivery of Nerve Growth Factor mRNA and Protein via Exosomes on Cerebral Ischemia
- (2020) Jialei Yang et al. Molecular Therapy-Nucleic Acids
- Functionalized polymeric hybrid micelles as an efficient nanotheranostic agent for thrombus imaging and thrombolysis
- (2020) Ying Wang et al. Acta Biomaterialia
- Constructing and evaluating caspase-activatable adeno-associated virus vector for gene delivery to the injured heart
- (2020) Mitchell J. Brun et al. JOURNAL OF CONTROLLED RELEASE
- Platelet membrane-functionalized nanoparticles with improved targeting ability and lower hemorrhagic risk for thrombolysis therapy
- (2020) Songli Wang et al. JOURNAL OF CONTROLLED RELEASE
- The Inclusion of a Matrix Metalloproteinase-9 Responsive Sequence in Self-assembled Peptide-based Brain-Targeting Nanoparticles Improves the Efficiency of Nanoparticles Crossing the Blood-Brain Barrier at Elevated MMP-9 Levels
- (2020) Yamir Islam et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Curcumin-laden exosomes target ischemic brain tissue and alleviate cerebral ischemia-reperfusion injury by inhibiting ROS-mediated mitochondrial apoptosis
- (2020) Ruyi He et al. Materials Science & Engineering C-Materials for Biological Applications
- Biomimetic fibrin-targeted and H2O2-responsive nanocarriers for thrombus therapy
- (2020) Yi Zhao et al. Nano Today
- Exosomes Derived from CXCR4-Overexpressing BMSC Promoted Activation of Microvascular Endothelial Cells in Cerebral Ischemia/Reperfusion Injury
- (2020) Xutong Li et al. NEURAL PLASTICITY
- Neural Stem Cells Transfected with Reactive Oxygen Species-Responsive Polyplexes for Effective Treatment of Ischemic Stroke
- (2019) Xin-Chi Jiang et al. ADVANCED MATERIALS
- Functional significance of the platelet immune receptors GPVI and CLEC-2
- (2019) Julie Rayes et al. JOURNAL OF CLINICAL INVESTIGATION
- Fabrication and evaluation a transferrin receptor targeting nano-drug carrier for cerebral infarction treatment
- (2019) Junyi Shen et al. Artificial Cells Nanomedicine and Biotechnology
- Exosome-mediated targeted delivery of miR-210 for angiogenic therapy after cerebral ischemia in mice
- (2019) Huixin Zhang et al. JOURNAL OF NANOBIOTECHNOLOGY
- Endogenous and Exogenous Stimuli-Responsive Drug Delivery Systems for Programmed Site-Specific Release
- (2019) Ali Raza et al. MOLECULES
- Low-Intensity Focused Ultrasound-Responsive Phase-Transitional Nanoparticles for Thrombolysis without Vascular Damage: A Synergistic Nonpharmaceutical Strategy
- (2019) Yixin Zhong et al. ACS Nano
- Ferrimagnetic Nanochains‐Based Mesenchymal Stem Cell Engineering for Highly Efficient Post‐Stroke Recovery
- (2019) Tianyuan Zhang et al. ADVANCED FUNCTIONAL MATERIALS
- Microthrombus‐Targeting Micelles for Neurovascular Remodeling and Enhanced Microcirculatory Perfusion in Acute Ischemic Stroke
- (2019) Yifei Lu et al. ADVANCED MATERIALS
- An activated-platelet-sensitive nanocarrier enables targeted delivery of tissue plasminogen activator for effective thrombolytic therapy
- (2019) Yu Huang et al. JOURNAL OF CONTROLLED RELEASE
- Thrombolysis induced by intravenous Administration of plasminogen activator in magnetoliposomes: dual targeting by magnetic and thermal manipulation
- (2019) Chih-Hsin Liu et al. Nanomedicine-Nanotechnology Biology and Medicine
- Near‐Infrared Light Activated Thermosensitive Ion Channel to Remotely Control Transgene System for Thrombolysis Therapy
- (2019) Da Zhang et al. Small
- Identification of variable lymphocyte receptors that can target therapeutics to pathologically exposed brain extracellular matrix
- (2019) Benjamin J. Umlauf et al. Science Advances
- Sequentially Site-Specific Delivery of Thrombolytics and Neuroprotectant for Enhanced Treatment of Ischemic Stroke
- (2019) Jianpei Xu et al. ACS Nano
- Nano-scaled MTCA-KKV: for targeting thrombus, releasing pharmacophores, inhibiting thrombosis and dissolving blood clots in vivo
- (2019) Shurui Zhao et al. International Journal of Nanomedicine
- Thrombus targeting aspirin particles for near infrared imaging and on-demand therapy of thrombotic vascular diseases
- (2019) Jeonghun Lee et al. JOURNAL OF CONTROLLED RELEASE
- The Flow Dependent Adhesion of von Willebrand Factor (VWF)-A1 Functionalized Nanoparticles in an in Vitro Coronary Stenosis Model
- (2019) Yathreb Asaad et al. MOLECULES
- Recognition, Intervention, and Monitoring of Neutrophils in Acute Ischemic Stroke
- (2019) Chunming Tang et al. NANO LETTERS
- Targeted Drug Delivery to Stroke via Chemotactic Recruitment of Nanoparticles Coated with Membrane of Engineered Neural Stem Cells
- (2019) Junning Ma et al. Small
- Selenium nanoparticles for targeted stroke therapy through modulation of inflammatory and metabolic signaling
- (2019) Hamed Amani et al. Scientific Reports
- Metal–Organic‐Framework‐Derived Carbon Nanostructures for Site‐Specific Dual‐Modality Photothermal/Photodynamic Thrombus Therapy
- (2019) Fengrong Zhang et al. Advanced Science
- Myocardial‐Infarction‐Responsive Smart Hydrogels Targeting Matrix Metalloproteinase for On‐Demand Growth Factor Delivery
- (2019) Caixia Fan et al. ADVANCED MATERIALS
- Polyacrylic acid-coated nanoparticles loaded with recombinant tissue plasminogen activator for the treatment of mice with ischemic stroke
- (2019) Lijie Huang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Polydopamine-modified dual-ligand nanoparticles as highly effective and targeted magnetic resonance/photoacoustic dual-modality thrombus imaging agents
- (2019) Yu Zhang et al. International Journal of Nanomedicine
- Shape effect in active targeting of nanoparticles to inflamed cerebral endothelium under static and flow conditions
- (2019) A. Da Silva-Candal et al. JOURNAL OF CONTROLLED RELEASE
- In vivo ultrasound-activated delivery of recombinant tissue plasminogen activator from the cavity of sub-micrometric capsules
- (2019) Clara Correa-Paz et al. JOURNAL OF CONTROLLED RELEASE
- Potential Neuroprotective Treatment of Stroke: Targeting Excitotoxicity, Oxidative Stress, and Inflammation
- (2019) Qianwen Yang et al. Frontiers in Neuroscience
- Nanotherapeutics: Engineering Cell Membrane-Based Nanotherapeutics to Target Inflammation (Adv. Sci. 15/2019)
- (2019) Huize Yan et al. Advanced Science
- Accessing neuroinflammation sites: Monocyte/neutrophil-mediated drug delivery for cerebral ischemia
- (2019) Jia Hou et al. Science Advances
- Selective Liposomal Transport through Blood Brain Barrier Disruption in Ischemic Stroke Reveals Two Distinct Therapeutic Opportunities
- (2019) Zahraa S. Al-Ahmady et al. ACS Nano
- Would Colloidal Gold Nanocarriers Present An Effective Diagnosis Or Treatment For Ischemic Stroke?
- (2019) Hamed Amani et al. International Journal of Nanomedicine
- Delivery of High Mobility Group Box-1 siRNA Using Brain-Targeting Exosomes for Ischemic Stroke Therapy
- (2019) Minkyung Kim et al. Journal of Biomedical Nanotechnology
- RGD-Modified Nanocarrier-Mediated Targeted Delivery of HIF-1α-AA Plasmid DNA to Cerebrovascular Endothelial Cells for Ischemic Stroke Treatment
- (2019) Lingna Deng et al. ACS Biomaterials-Science & Engineering
- Platelets as Modulators of Cerebral Ischemia/Reperfusion Injury
- (2019) David Stegner et al. Frontiers in Immunology
- Engineered Nanoplatelets for Targeted Delivery of Plasminogen Activators to Reverse Thrombus in Multiple Mouse Thrombosis Models
- (2019) Junchao Xu et al. ADVANCED MATERIALS
- Engineered antibody-functionalized porous silicon nanoparticles for therapeutic targeting of pro-survival pathway in endogenous neuroblasts after stroke
- (2019) Vimalkumar Balasubramanian et al. BIOMATERIALS
- Bioinspired Nanosponge for Salvaging Ischemic Stroke via Free Radical Scavenging and Self-Adapted Oxygen Regulating
- (2019) Jinjin Shi et al. NANO LETTERS
- Chitosan nanoparticles release nimodipine in response to tissue acidosis to attenuate spreading depolarization evoked during forebrain ischemia
- (2019) Orsolya M. Tóth et al. NEUROPHARMACOLOGY
- Targeting Human Thrombus by Liposomes Modified with Anti-Fibrin Protein Binders
- (2019) Hana Petroková et al. Pharmaceutics
- Erythrocyte Membrane Modified Janus Polymeric Motors for Thrombus Therapy
- (2018) Jingxin Shao et al. ACS Nano
- Bioengineered Boronic Ester Modified Dextran Polymer Nanoparticles as Reactive Oxygen Species Responsive Nanocarrier for Ischemic Stroke Treatment
- (2018) Wei Lv et al. ACS Nano
- Simultaneous Blood–Brain Barrier Crossing and Protection for Stroke Treatment Based on Edaravone-Loaded Ceria Nanoparticles
- (2018) Qunqun Bao et al. ACS Nano
- Cyclic RGD functionalized liposomes encapsulating urokinase for thrombolysis
- (2018) Nengpan Zhang et al. Acta Biomaterialia
- Targeting RAGE Signaling in Inflammatory Disease
- (2018) Barry I. Hudson et al. Annual Review of Medicine
- Glycosaminoglycan-based hybrid hydrogel encapsulated with polyelectrolyte complex nanoparticles for endogenous stem cell regulation in central nervous system regeneration
- (2018) Wei-Hong Jian et al. BIOMATERIALS
- Surface functionalized exosomes as targeted drug delivery vehicles for cerebral ischemia therapy
- (2018) Tian Tian et al. BIOMATERIALS
- Thrombolytic therapy based on fucoidan-functionalized polymer nanoparticles targeting P-selectin
- (2018) Maya Juenet et al. BIOMATERIALS
- Heart Disease and Stroke Statistics—2018 Update: A Report From the American Heart Association
- (2018) Emelia J. Benjamin et al. CIRCULATION
- Circulating Platelets as Mediators of Immunity, Inflammation, and Thrombosis
- (2018) Milka Koupenova et al. CIRCULATION RESEARCH
- Thrombus Formation and Propagation in the Onset of Cardiovascular Events
- (2018) Yujiro Asada et al. Journal of Atherosclerosis and Thrombosis
- G5G2.5 core-shell tecto-dendrimer specifically targets reactive glia in brain ischemia
- (2018) Veronica Murta et al. JOURNAL OF NEUROCHEMISTRY
- Design of Magnetically Labeled Cells (Mag-Cells) for in Vivo Control of Stem Cell Migration and Differentiation
- (2018) Seokhwan Yun et al. NANO LETTERS
- The diosgenin prodrug nanoparticles with pH-responsive as a drug delivery system uniquely prevents thrombosis without increased bleeding risk
- (2018) Zeliang Wei et al. Nanomedicine-Nanotechnology Biology and Medicine
- Spreading depolarization is not an epiphenomenon but the principal mechanism of the cytotoxic edema in various gray matter structures of the brain during stroke
- (2018) Jens P. Dreier et al. NEUROPHARMACOLOGY
- Leukemia Inhibitory Factor-Loaded Nanoparticles with Enhanced Cytokine Metabolic Stability and Anti-Inflammatory Activity
- (2018) Stephanie M. Davis et al. PHARMACEUTICAL RESEARCH
- Blood-brain barrier dysfunction and recovery after ischemic stroke
- (2018) Xiaoyan Jiang et al. PROGRESS IN NEUROBIOLOGY
- Targeted complement inhibition salvages stressed neurons and inhibits neuroinflammation after stroke in mice
- (2018) Ali Alawieh et al. Science Translational Medicine
- Near-infrared light-triggered drug release from UV-responsive diblock copolymer-coated upconversion nanoparticles with high monodispersity
- (2018) Jun Xiang et al. Journal of Materials Chemistry B
- Tissue Plasminogen Activator-Porous Magnetic Microrods for Targeted Thrombolytic Therapy after Ischemic Stroke
- (2018) Jiangnan Hu et al. ACS Applied Materials & Interfaces
- Thrombin-Responsive, Brain-Targeting Nanoparticles for Improved Stroke Therapy
- (2018) Xing Guo et al. ACS Nano
- Synthetic α5β1 integrin ligand PHSRN is proangiogenic and neuroprotective in cerebral ischemic stroke
- (2018) Cheng-Chun Wu et al. BIOMATERIALS
- A Road to Bring Brij52 Back to Attention: Shear Stress Sensitive Brij52 Niosomal Carriers for Targeted Drug Delivery to Obstructed Blood Vessels
- (2018) Shokouh Arjmand et al. MEDICAL HYPOTHESES
- Erythrocyte-Inspired Discoidal Polymeric Nanoconstructs Carrying Tissue Plasminogen Activator for the Enhanced Lysis of Blood Clots
- (2018) Marianna Colasuonno et al. ACS Nano
- Stimulating brain recovery after stroke using theranostic albumin nanocarriers loaded with nerve growth factor in combination therapy
- (2018) Tivadar Feczkó et al. JOURNAL OF CONTROLLED RELEASE
- PAMAM dendrimers: blood-brain barrier transport and neuronal uptake after focal brain ischemia
- (2018) Sofia D. Santos et al. JOURNAL OF CONTROLLED RELEASE
- MMP-9 Upregulation is Attenuated by the Monoclonal TLR2 Antagonist T2.5 After Oxygen–Glucose Deprivation and Reoxygenation in Rat Brain Microvascular Endothelial Cells
- (2018) Hongyan Zhu et al. Journal of Stroke & Cerebrovascular Diseases
- Decision shaping neutrophil-platelet interplay in inflammation: From physiology to intervention
- (2017) Oliver Soehnlein EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
- Ginsenoside Rg1 nanoparticle penetrating the blood–brain barrier to improve the cerebral function of diabetic rats complicated with cerebral infarction
- (2017) Junyi Shen et al. International Journal of Nanomedicine
- Complications of endovascular treatment for acute ischemic stroke: Prevention and management
- (2017) Joyce S Balami et al. International Journal of Stroke
- Fabrication of ultrasound-responsive microbubbles via coaxial electrohydrodynamic atomization for triggered release of tPA
- (2017) Wei-Cheng Yan et al. JOURNAL OF COLLOID AND INTERFACE SCIENCE
- Self-assembled amphiphilic core-shell nanocarriers in line with the modern strategies for brain delivery
- (2017) Reham S. Elezaby et al. JOURNAL OF CONTROLLED RELEASE
- ZL006 promotes migration and differentiation of transplanted neural stem cells in male rats after stroke
- (2017) Dong-Liang Wang et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Shear-sensitive nanocapsule drug release for site-specific inhibition of occlusive thrombus formation
- (2017) C. P. Molloy et al. JOURNAL OF THROMBOSIS AND HAEMOSTASIS
- Inflammation and thrombosis: roles of neutrophils, platelets and endothelial cells and their interactions in thrombus formation during sepsis
- (2017) T. Iba et al. JOURNAL OF THROMBOSIS AND HAEMOSTASIS
- Uptake of dendrimer-drug by different cell types in the hippocampus after hypoxic–ischemic insult in neonatal mice: Effects of injury, microglial activation and hypothermia
- (2017) Christina L. Nemeth et al. Nanomedicine-Nanotechnology Biology and Medicine
- Vascular expression of angiopoietin1, α5β1 integrin and tight junction proteins is tightly regulated during vascular remodeling in the post-ischemic brain
- (2017) Jialan Sun et al. NEUROSCIENCE
- Enhanced transport of plant-produced rabies single-chain antibody-RVG peptide fusion protein across an in cellulo blood-brain barrier device
- (2017) Waranyoo Phoolcharoen et al. PLANT BIOTECHNOLOGY JOURNAL
- Mechanical thrombectomy in acute ischemic stroke
- (2017) L. Derex et al. REVUE NEUROLOGIQUE
- Enhanced Fibrinolysis with Magnetically Powered Colloidal Microwheels
- (2017) Tonguc O. Tasci et al. Small
- Concise Review: MSC Adhesion Cascade-Insights into Homing and Transendothelial Migration
- (2017) Franziska Nitzsche et al. STEM CELLS
- Inhibition of CD147 (Cluster of Differentiation 147) Ameliorates Acute Ischemic Stroke in Mice by Reducing Thromboinflammation
- (2017) Rong Jin et al. STROKE
- Transplantation of bFGF-expressing neural stem cells promotes cell migration and functional recovery in rat brain after transient ischemic stroke
- (2017) Jin-Jing Zhang et al. Oncotarget
- Edaravone-Encapsulated Agonistic Micelles Rescue Ischemic Brain Tissue by Tuning Blood-Brain Barrier Permeability
- (2017) Qu Jin et al. Theranostics
- Direct Macromolecular Drug Delivery to Cerebral Ischemia Area using Neutrophil-Mediated Nanoparticles
- (2017) Chun Zhang et al. Theranostics
- Novel Thrombolytic Drug Based on Thrombin Cleavable Microplasminogen Coupled to a Single‐Chain Antibody Specific for Activated GPIIb/IIIa
- (2017) Thomas Bonnard et al. Journal of the American Heart Association
- Exosome Mediated Delivery of miR-124 Promotes Neurogenesis after Ischemia
- (2017) Jialei Yang et al. Molecular Therapy-Nucleic Acids
- Synthetic/ECM-inspired hybrid platform for hollow microcarriers with ROS-triggered nanoporation hallmarks
- (2017) Gesmi Milcovich et al. Scientific Reports
- Enhancement in the Neuroprotective Power of Riluzole Against Cerebral Ischemia Using a Brain Targeted Drug Delivery Vehicle
- (2016) Shashi K. Verma et al. ACS Applied Materials & Interfaces
- Nanoscale effects in dendrimer-mediated targeting of neuroinflammation
- (2016) Elizabeth Nance et al. BIOMATERIALS
- H2O2-triggered bubble generating antioxidant polymeric nanoparticles as ischemia/reperfusion targeted nanotheranostics
- (2016) Changsun Kang et al. BIOMATERIALS
- Neuroprotection against cerebral ischemia/reperfusion injury by intravenous administration of liposomal fasudil
- (2016) Tatsuya Fukuta et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- pH gradient difference around ischemic brain tissue can serve as a trigger for delivering polyethylene glycol-conjugated urokinase nanogels
- (2016) Wei Cui et al. JOURNAL OF CONTROLLED RELEASE
- Dual targeted nanocarrier for brain ischemic stroke treatment
- (2016) Yue Zhao et al. JOURNAL OF CONTROLLED RELEASE
- Microglial migration and interactions with dendrimer nanoparticles are altered in the presence of neuroinflammation
- (2016) Fan Zhang et al. Journal of Neuroinflammation
- In Vitro Evaluation of Focused Ultrasound-Enhanced TNK-Tissue Plasminogen Activator-Mediated Thrombolysis
- (2016) Nikolaos Papadopoulos et al. Journal of Stroke & Cerebrovascular Diseases
- Targeted drug delivery to ischemic stroke via chlorotoxin-anchored, lexiscan-loaded nanoparticles
- (2016) Liang Han et al. Nanomedicine-Nanotechnology Biology and Medicine
- Inhibition of cerebral vascular inflammation by brain endothelium-targeted oligodeoxynucleotide complex
- (2016) Jing Hu et al. NEUROSCIENCE
- Co-Assembly of Heparin and Polypeptide Hybrid Nanoparticles for Biomimetic Delivery and Anti-Thrombus Therapy
- (2016) Chengjun Chen et al. Small
- Label-free CEST MRI Detection of Citicoline-Liposome Drug Delivery in Ischemic Stroke
- (2016) Huanling Liu et al. Theranostics
- Extending the Time Window for Endovascular and Pharmacological Reperfusion
- (2016) Nils Henninger et al. Translational Stroke Research
- In Vitro Evaluation of Focused Ultrasound-Enhanced TNK-Tissue Plasminogen Activator-Mediated Thrombolysis
- (2016) Nikolaos Papadopoulos et al. Journal of Stroke & Cerebrovascular Diseases
- Neural Stem Cells and Ischemic Brain
- (2016) Zhenggang Zhang et al. Journal of Stroke
- TPA Immobilization on Iron Oxide Nanocubes and Localized Magnetic Hyperthermia Accelerate Blood Clot Lysis
- (2015) Eszter Voros et al. ADVANCED FUNCTIONAL MATERIALS
- Multifunctional Thrombin-Activatable Polymer Capsules for Specific Targeting to Activated Platelets
- (2015) Sylvia T. Gunawan et al. ADVANCED MATERIALS
- Salvaging brain ischemia by increasing neuroprotectant uptake via nanoagonist mediated blood brain barrier permeability enhancement
- (2015) Shuyan Zheng et al. BIOMATERIALS
- Enhancing neurogenesis and angiogenesis with target delivery of stromal cell derived factor-1α using a dual ionic pH-sensitive copolymer
- (2015) Dong Hee Kim et al. BIOMATERIALS
- Plasminogen associates with phosphatidylserine-exposing platelets and contributes to thrombus lysis under flow
- (2015) C. S. Whyte et al. BLOOD
- Enzymatically-responsive pro-angiogenic peptide-releasing poly(ethylene glycol) hydrogels promote vascularization in vivo
- (2015) Amy H. Van Hove et al. JOURNAL OF CONTROLLED RELEASE
- Protein Kinase C-Dependent Growth-Associated Protein 43 Phosphorylation Regulates Gephyrin Aggregation at Developing GABAergic Synapses
- (2015) Chen-Yu Wang et al. MOLECULAR AND CELLULAR BIOLOGY
- Update on the Global Burden of Ischemic and Hemorrhagic Stroke in 1990-2013: The GBD 2013 Study
- (2015) Valery L. Feigin et al. NEUROEPIDEMIOLOGY
- Increased expression and colocalization of GAP43 and CASP3 after brain ischemic lesion in mouse
- (2015) Dunja Gorup et al. NEUROSCIENCE LETTERS
- Caspase Functions in Cell Death and Disease: Figure 1.
- (2015) David R. McIlwain et al. Cold Spring Harbor Perspectives in Biology
- Direct Imaging of Cerebral Thromboemboli Using Computed Tomography and Fibrin-targeted Gold Nanoparticles
- (2015) Jeong-Yeon Kim et al. Theranostics
- Temporally Tunable, Enzymatically Responsive Delivery of Proangiogenic Peptides from Poly(ethylene glycol) Hydrogels
- (2015) Amy H. Van Hove et al. Advanced Healthcare Materials
- Overcoming the Blood–Brain Barrier for Delivering Drugs into the Brain by Using Adenosine Receptor Nanoagonist
- (2014) Xihui Gao et al. ACS Nano
- Targeted Antithrombotic Protein Micelles
- (2014) Wookhyun Kim et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Receptor for AGEs (RAGE) as Mediator of NF-kB Pathway Activation in Neuroinflammation and Oxidative Stress
- (2014) Julio Tobon-Velasco et al. CNS & Neurological Disorders-Drug Targets
- Brain endothelial cell specific integrins and ischemic stroke
- (2014) Kathleen Guell et al. Expert Review of Neurotherapeutics
- Role of CCR2 in Inflammatory Conditions of the Central Nervous System
- (2014) Hannah X Chu et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Bio-responsive delivery of tissue plasminogen activator for localized thrombolysis
- (2014) Shahriar Absar et al. JOURNAL OF CONTROLLED RELEASE
- Thrombin-inhibiting nanoparticles rapidly constitute versatile and detectable anticlotting surfaces
- (2014) Jacob Wheatley Myerson et al. NANOTECHNOLOGY
- Injectable and bioresponsive hydrogels for on-demand matrix metalloproteinase inhibition
- (2014) Brendan P. Purcell et al. NATURE MATERIALS
- Fibrinogen and red blood cells in venous thrombosis
- (2014) Maria M. Aleman et al. THROMBOSIS RESEARCH
- Nanosized Aspirin-Arg-Gly-Asp-Val: Delivery of Aspirin to Thrombus by the Target Carrier Arg-Gly-Asp-Val Tetrapeptide
- (2013) Shaoming Jin et al. ACS Nano
- Silica-coated superparamagnetic iron oxide nanoparticles targeting of EPCs in ischemic brain injury
- (2013) Qianyun Li et al. BIOMATERIALS
- Targeted delivery of Neurogenin-2 protein in the treatment for cerebral ischemia-reperfusion injury
- (2013) Bin Deng et al. BIOMATERIALS
- The effect of cationic albumin-conjugated PEGylated tanshinone IIA nanoparticles on neuronal signal pathways and neuroprotection in cerebral ischemia
- (2013) Xin Liu et al. BIOMATERIALS
- Targeted therapy of brain ischaemia using Fas ligand antibody conjugated PEG-lipid nanoparticles
- (2013) Ying-mei Lu et al. BIOMATERIALS
- Hydrogen Peroxide Promotes Aging-Related Platelet Hyperactivation and Thrombosis
- (2013) Sanjana Dayal et al. CIRCULATION
- The late response of rat subependymal zone stem and progenitor cells to stroke is restricted to directly affected areas of their niche
- (2013) Ilias Kazanis et al. EXPERIMENTAL NEUROLOGY
- The significance of matrix metalloproteinase (MMP)-2 and MMP-9 in the ischemic stroke
- (2013) Jacek Kurzepa et al. INTERNATIONAL JOURNAL OF NEUROSCIENCE
- Nanoparticles for Targeted Delivery of Antioxidant Enzymes to the Brain after Cerebral Ischemia and Reperfusion Injury
- (2013) Xiang Yun et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- The transition of prothrombin to thrombin
- (2013) S. Krishnaswamy JOURNAL OF THROMBOSIS AND HAEMOSTASIS
- Migration of neural stem cells to ischemic brain regions in ischemic stroke in rats
- (2013) Jiong Dai et al. NEUROSCIENCE LETTERS
- Thrombus-Targeted Nanocarrier Attenuates Bleeding Complications Associated with Conventional Thrombolytic Therapy
- (2013) Shahriar Absar et al. PHARMACEUTICAL RESEARCH
- Nanoparticle encapsulation in red blood cells enables blood-pool magnetic particle imaging hours after injection
- (2013) J Rahmer et al. PHYSICS IN MEDICINE AND BIOLOGY
- Exosomes for targeted siRNA delivery across biological barriers
- (2012) Samir EL Andaloussi et al. ADVANCED DRUG DELIVERY REVIEWS
- Platelet Mimetic Particles for Targeting Thrombi in Flowing Blood
- (2012) Nishit Doshi et al. ADVANCED MATERIALS
- Ratiometric Activatable Cell-Penetrating Peptides Provide Rapid In Vivo Readout of Thrombin Activation
- (2012) Michael Whitney et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Bone marrow mononuclear cells and mannose receptor expression in focal cortical ischemia
- (2012) Arthur Giraldi-Guimarães et al. BRAIN RESEARCH
- Amelioration of cerebral ischemia–reperfusion injury based on liposomal drug delivery system with asialo-erythropoietin
- (2012) Takayuki Ishii et al. JOURNAL OF CONTROLLED RELEASE
- Minocycline-Preconditioned Neural Stem Cells Enhance Neuroprotection after Ischemic Stroke in Rats
- (2012) H. Sakata et al. JOURNAL OF NEUROSCIENCE
- A New Drug Delivery System for Intravenous Coronary Thrombolysis With Thrombus Targeting and Stealth Activity Recoverable by Ultrasound
- (2012) Hiroyuki Kawata et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Overexpression of CXCR4 in mesenchymal stem cells promotes migration, neuroprotection and angiogenesis in a rat model of stroke
- (2012) Xiaolan Yu et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Update on the Role of Cannabinoid Receptors after Ischemic Stroke
- (2012) Luciano S. A. Capettini et al. MEDIATORS OF INFLAMMATION
- Multifunctional nanoagent for thrombus-targeted fibrinolytic therapy
- (2012) Jason R McCarthy et al. Nanomedicine
- Shear-stress sensitive lenticular vesicles for targeted drug delivery
- (2012) Margaret N. Holme et al. Nature Nanotechnology
- Molecular MRI enables early and sensitive detection of brain metastases
- (2012) S. Serres et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Leveraging Shear Stress to Bust Clots with Nanoparticles
- (2012) E. Lavik et al. SCIENCE
- Concise Review: Adipose-Derived Stem Cells as a Novel Tool for Future Regenerative Medicine
- (2012) Hiroshi Mizuno et al. STEM CELLS
- Microglia/Macrophage Polarization Dynamics Reveal Novel Mechanism of Injury Expansion After Focal Cerebral Ischemia
- (2012) Xiaoming Hu et al. STROKE
- The promotion of cerebral ischemia recovery in rats by laminin-binding BDNF
- (2011) Qianqian Han et al. BIOMATERIALS
- Peptide-conjugated polyamidoamine dendrimer as a nanoscale tumor-targeted T1 magnetic resonance imaging contrast agent
- (2011) Liang Han et al. BIOMATERIALS
- Upregulation of fibronectin and the α5β1 and αvβ3 integrins on blood vessels within the cerebral ischemic penumbra
- (2011) Longxuan Li et al. EXPERIMENTAL NEUROLOGY
- Thrombin-inhibiting perfluorocarbon nanoparticles provide a novel strategy for the treatment and magnetic resonance imaging of acute thrombosis
- (2011) J. MYERSON et al. JOURNAL OF THROMBOSIS AND HAEMOSTASIS
- Platelet adhesion and activation mechanisms in arterial thrombosis and ischaemic stroke
- (2011) B. NIESWANDT et al. JOURNAL OF THROMBOSIS AND HAEMOSTASIS
- Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes
- (2011) Lydia Alvarez-Erviti et al. NATURE BIOTECHNOLOGY
- Ischemia and reperfusion—from mechanism to translation
- (2011) Holger K Eltzschig et al. NATURE MEDICINE
- RAGE mediates vascular injury and inflammation after global cerebral ischemia
- (2011) Tomoya Kamide et al. NEUROCHEMISTRY INTERNATIONAL
- Stromal-Derived Factor-1α Correlates With Circulating Endothelial Progenitor Cells and With Acute Lesion Volume in Stroke Patients
- (2011) Tanya Bogoslovsky et al. STROKE
- The Preparation of a New Self-Made Microbubble-Loading Urokinase and Its Thrombolysis Combined with Low-Frequency Ultrasound In Vitro
- (2011) Shu-Ting Ren et al. ULTRASOUND IN MEDICINE AND BIOLOGY
- Development and characterization of site specific target sensitive liposomes for the delivery of thrombolytic agents
- (2010) Bhuvaneshwar Vaidya et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Wall shear over high degree stenoses pertinent to atherothrombosis
- (2010) David L. Bark et al. JOURNAL OF BIOMECHANICS
- An ultrasound-responsive nano delivery system of tissue-type plasminogen activator for thrombolytic therapy
- (2010) Yoshiko Uesugi et al. JOURNAL OF CONTROLLED RELEASE
- Comparison of five different targeting ligands to enhance accumulation of liposomes into the brain
- (2010) Inge van Rooy et al. JOURNAL OF CONTROLLED RELEASE
- Spatial Distribution of Factor Xa, Thrombin, and Fibrin(ogen) on Thrombi at Venous Shear
- (2010) Michelle A. Berny et al. PLoS One
- Recent progress in phospholipase A2 research: From cells to animals to humans
- (2010) Makoto Murakami et al. PROGRESS IN LIPID RESEARCH
- Exosomes – vesicular carriers for intercellular communication
- (2009) Mikael Simons et al. CURRENT OPINION IN CELL BIOLOGY
- Oxidative risk for atherothrombotic cardiovascular disease
- (2009) Jane A. Leopold et al. FREE RADICAL BIOLOGY AND MEDICINE
- Clinical determinants of infarct pattern subtypes in large vessel atherosclerotic stroke
- (2009) Oh Young Bang et al. JOURNAL OF NEUROLOGY
- Plasma and Brain Matrix Metalloproteinase-9 After Acute Focal Cerebral Ischemia in Rats
- (2009) Kyung-Pil Park et al. STROKE
- Oxidative Stress and Platelets
- (2008) Jane E. Freedman ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Affinity of low molecular weight fucoidan for P-selectin triggers its binding to activated human platelets
- (2008) Laure Bachelet et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Detection of apoptosis in a rat model of focal cerebral ischemia using a homing peptide selected from in vivo phage display
- (2008) Hai-Yan Hong et al. JOURNAL OF CONTROLLED RELEASE
- Systemic Inflammation Alters the Kinetics of Cerebrovascular Tight Junction Disruption after Experimental Stroke in Mice
- (2008) B. W. McColl et al. JOURNAL OF NEUROSCIENCE
- Modulation of the balance between cannabinoid CB1 and CB2 receptor activation during cerebral ischemic/reperfusion injury
- (2008) M. Zhang et al. NEUROSCIENCE
- Therapeutic potential of erythropoietin and its structural or functional variants in the nervous system
- (2008) Anna-Leena Sirén et al. Neurotherapeutics
- Mechanisms of Thrombus Formation
- (2008) Bruce Furie et al. NEW ENGLAND JOURNAL OF MEDICINE
- Aptamer-based endocytosis of a lysosomal enzyme
- (2008) C.-h. B. Chen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Construction and functional evaluation of hirudin derivatives with low bleeding risk
- (2008) Chuanling Zhang et al. THROMBOSIS AND HAEMOSTASIS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More