Accelerating thrombolysis using a precision and clot-penetrating drug delivery strategy by nanoparticle-shelled microbubbles

Low-Intensity Focused Ultrasound-Responsive Phase-Transitional Nanoparticles for Thrombolysis without Vascular Damage: A Synergistic Nonpharmaceutical Strategy

(2019) Yixin Zhong et al.   ACS Nano

Sequentially Site-Specific Delivery of Thrombolytics and Neuroprotectant for Enhanced Treatment of Ischemic Stroke

(2019) Jianpei Xu et al.   ACS Nano

Engineered Nanoplatelets for Targeted Delivery of Plasminogen Activators to Reverse Thrombus in Multiple Mouse Thrombosis Models

(2019) Junchao Xu et al.   ADVANCED MATERIALS

Erythrocyte Membrane Modified Janus Polymeric Motors for Thrombus Therapy

(2018) Jingxin Shao et al.   ACS Nano

Tissue Plasminogen Activator-Porous Magnetic Microrods for Targeted Thrombolytic Therapy after Ischemic Stroke

(2018) Jiangnan Hu et al.   ACS Applied Materials & Interfaces

Erythrocyte-Inspired Discoidal Polymeric Nanoconstructs Carrying Tissue Plasminogen Activator for the Enhanced Lysis of Blood Clots

(2018) Marianna Colasuonno et al.   ACS Nano

Enhanced Fibrinolysis with Magnetically Powered Colloidal Microwheels

(2017) Tonguc O. Tasci et al.   Small

Novel Thrombolytic Drug Based on Thrombin Cleavable Microplasminogen Coupled to a Single‐Chain Antibody Specific for Activated GPIIb/IIIa

(2017) Thomas Bonnard et al.   Journal of the American Heart Association

Engineered Nanoplatelets for Enhanced Treatment of Multiple Myeloma and Thrombus

(2016) Quanyin Hu et al.   ADVANCED MATERIALS

NOR-SASS (Norwegian Sonothrombolysis in Acute Stroke Study)

(2016) Aliona Nacu et al.   STROKE

Controlled nanoparticle release from stable magnetic microbubble oscillations

(2016) Yu Gao et al.   NPG Asia Materials

TPA Immobilization on Iron Oxide Nanocubes and Localized Magnetic Hyperthermia Accelerate Blood Clot Lysis

(2015) Eszter Voros et al.   ADVANCED FUNCTIONAL MATERIALS

Multifunctional Thrombin-Activatable Polymer Capsules for Specific Targeting to Activated Platelets

(2015) Sylvia T. Gunawan et al.   ADVANCED MATERIALS

A t-PA/nanoparticle conjugate with fully retained enzymatic activity and prolonged circulation time

(2015) Zengchao Tang et al.   Journal of Materials Chemistry B

Construction and Evaluation of Fe3O4-Based PLGA Nanoparticles Carrying rtPA Used in the Detection of Thrombosis and in Targeted Thrombolysis

(2014) Jun Zhou et al.   ACS Applied Materials & Interfaces

Self-Titrating Anticoagulant Nanocomplexes That Restore Homeostatic Regulation of the Coagulation Cascade

(2014) Kevin Y. Lin et al.   ACS Nano

Acceleration of Tissue Plasminogen Activator-Mediated Thrombolysis by Magnetically Powered Nanomotors

(2014) Rui Cheng et al.   ACS Nano

Lipid Shedding from Single Oscillating Microbubbles

(2014) Ying Luan et al.   ULTRASOUND IN MEDICINE AND BIOLOGY

Advanced drug delivery systems for antithrombotic agents

(2013) C. F. Greineder et al.   BLOOD

Thrombus-Targeted Nanocarrier Attenuates Bleeding Complications Associated with Conventional Thrombolytic Therapy

(2013) Shahriar Absar et al.   PHARMACEUTICAL RESEARCH

Targeted microbubbles in the experimental and clinical setting

(2012) Ahmed Alzaraa et al.   AMERICAN JOURNAL OF SURGERY

Shear-Activated Nanotherapeutics for Drug Targeting to Obstructed Blood Vessels

(2012) N. Korin et al.   SCIENCE

Ultrasound-Enhanced Thrombolytic Effect of Tissue Plasminogen Activator–Loaded Echogenic Liposomes in an In Vivo Rabbit Aorta Thrombus Model—Brief Report

(2011) Susan T. Laing et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

A fibrin-specific thrombolytic nanomedicine approach to acute ischemic stroke

(2011) Jon N Marsh et al.   Nanomedicine

Blood Vessel Deformations on Microsecond Time Scales by Ultrasonic Cavitation

(2011) Hong Chen et al.   PHYSICAL REVIEW LETTERS

Thrombolytic efficacy of tissue plasminogen activator-loaded echogenic liposomes in a rabbit thrombus model

(2011) Susan T. Laing et al.   THROMBOSIS RESEARCH

Blood vessel rupture by cavitation

(2010) Hong Chen et al.   UROLOGICAL RESEARCH

Direct fibrinolytic agents: biochemical attributes, preclinical foundation and clinical potential

(2009) V. J. MARDER et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Thrombolysis, stroke-unit admission and early rehabilitation in elderly patients

(2009) Laurent Derex et al.   Nature Reviews Neurology

Triggers, targets and treatments for thrombosis

(2008) Nigel Mackman   NATURE

Mechanisms of Thrombus Formation

(2008) Bruce Furie et al.   NEW ENGLAND JOURNAL OF MEDICINE