A Growing Link between Circadian Rhythms, Type 2 Diabetes Mellitus and Alzheimer’s Disease

Association between Time Restricted Feeding and Cognitive Status in Older Italian Adults

(2021) Walter Currenti et al.   Nutrients

Melatonin prevents diabetes‐associated cognitive dysfunction from microglia‐mediated neuroinflammation by activating autophagy via TLR4/Akt/mTOR pathway

(2021) Yixin Cui et al.   FASEB JOURNAL

Evaluation of SAMP8 Mice as a Model for Sleep-Wake and Rhythm Disturbances Associated with Alzheimer’s Disease: Impact of Treatment with the Dual Orexin (Hypocretin) Receptor Antagonist Lemborexant

(2021) Carsten T. Beuckmann et al.   JOURNAL OF ALZHEIMERS DISEASE

Deciphering the Interacting Mechanisms of Circadian Disruption and Alzheimer’s Disease

(2021) Md. Sahab Uddin et al.   NEUROCHEMICAL RESEARCH

Association of Serum Melatonin Level with Mild Cognitive Impairment in Type 2 Diabetic Patients: A Cross-Sectional Study

(2021) Jichen Zhang et al.   International Journal of Endocrinology

Circadian disruption by short light exposure and a high energy diet impairs glucose tolerance and increases cardiac fibrosis in Psammomys obesus

(2021) Victoria A. Nankivell et al.   Scientific Reports

Neuroprotective Effects of Fluoxetine on Molecular Markers of Circadian Rhythm, Cognitive Deficits, Oxidative Damage, and Biomarkers of Alzheimer’s Disease-Like Pathology Induced under Chronic Constant Light Regime in Wistar Rats

(2021) Ashish Sharma et al.   ACS Chemical Neuroscience

Sleep disorders in people with type 2 diabetes and associated health outcomes: a review of the literature

(2021) Samantha B. J. Schipper et al.   DIABETOLOGIA

Disruption of Circadian Clocks Promotes Progression of Alzheimer’s Disease in Diabetic Mice

(2021) Jiaojiao Huang et al.   MOLECULAR NEUROBIOLOGY

Dissecting and modeling photic and melanopsin effects to predict sleep disturbances induced by irregular light exposure in mice

(2021) Jeffrey Hubbard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bright daytime light enhances circadian amplitude in a diurnal mammal

(2021) Beatriz Bano-Otalora et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Effects of Intermittent Fasting on Brain and Cognitive Function

(2021) Jip Gudden et al.   Nutrients

Effects of the Clock Modulator Nobiletin on Circadian Rhythms and Pathophysiology in Female Mice of an Alzheimer’s Disease Model

(2021) Eunju Kim et al.   Biomolecules

Circadian Rhythm Dysregulation and Restoration: The Role of Melatonin

(2021) Clayton Vasey et al.   Nutrients

Polysomnographic assessment of suvorexant in patients with probable Alzheimer's disease dementia and insomnia: a randomized trial

(2020) W. Joseph Herring et al.   Alzheimers & Dementia

Impact of circadian disruption on glucose metabolism: implications for type 2 diabetes

(2020) Ivy C. Mason et al.   DIABETOLOGIA

Orexin-A exacerbates Alzheimer’s disease by inducing mitochondrial impairment

(2020) Maoyu Li et al.   NEUROSCIENCE LETTERS

In pancreatic islets from type 2 diabetes patients, the dampened circadian oscillators lead to reduced insulin and glucagon exocytosis

(2020) Volodymyr Petrenko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Delayed Morning and Earlier Evening Time-Restricted Feeding Protocol for Improving Glycemic Control and Dietary Adherence in Men with Overweight/Obesity: A Randomized Controlled Trial

(2020) Evelyn B. Parr et al.   Nutrients

Physical exercise in the prevention and treatment of Alzheimer's disease

(2020) Adrian De la Rosa et al.   Journal of Sport and Health Science

Circadian rhythm disruption and mental health

(2020) William H. Walker et al.   Translational Psychiatry

Western Diet-Induced Obesity Disrupts the Diurnal Rhythmicity of Hippocampal Core Clock Gene Expression in a Mouse Model

(2020) Lauren N. Woodie et al.   BRAIN BEHAVIOR AND IMMUNITY

A New Neurovascular Panel Discriminates Between Patients with Type 2 Diabetes Mellitus with Cognitive Impairment and Cognitive Impairment Alone

(2020) Weiwei Zhang et al.   JOURNAL OF ALZHEIMERS DISEASE

Exercise Training Impacts Skeletal Muscle Clock in Adults with Prediabetes

(2020) Melissa L. Erickson et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

Chrono-nutrition for the prevention and treatment of obesity and type 2 diabetes: from mice to men

(2020) John A. Hawley et al.   DIABETOLOGIA

Cognitive Impact of Calorie Restriction: A Narrative Review

(2020) Qian Yu et al.   Journal of the American Medical Directors Association

The wrinkling of time: Aging, inflammation, oxidative stress, and the circadian clock in neurodegeneration

(2020) Brian V. Lananna et al.   NEUROBIOLOGY OF DISEASE

How to schedule night shift work in order to reduce health and safety risks

(2020) Anne Helene Garde et al.   SCANDINAVIAN JOURNAL OF WORK ENVIRONMENT & HEALTH

The beneficial effects of intermittent fasting: an update on mechanism, and the role of circadian rhythm and gut microbiota

(2020) Dandan Hu et al.   Hepatobiliary Surgery and Nutrition

Melatonin regulates Aβ production/clearance balance and Aβ neurotoxicity: A potential therapeutic molecule for Alzheimer’s disease

(2020) Yuanming Li et al.   BIOMEDICINE & PHARMACOTHERAPY

Chi3l1/YKL-40 is controlled by the astrocyte circadian clock and regulates neuroinflammation and Alzheimer’s disease pathogenesis

(2020) Brian V. Lananna et al.   Science Translational Medicine

The sleep-wake cycle regulates brain interstitial fluid tau in mice and CSF tau in humans

(2019) Jerrah K. Holth et al.   SCIENCE

Association between circadian rhythms and neurodegenerative diseases

(2019) Yue Leng et al.   LANCET NEUROLOGY

Effects of Light Therapy on Mood and Insulin Sensitivity in Patients With Type 2 Diabetes and Depression: Results From a Randomized Placebo-Controlled Trial

(2019) Annelies Brouwer et al.   DIABETES CARE

Shift Work, Chronotype, and Melatonin Rhythm in Nurses

(2019) Pedram Razavi et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Cellular circadian period length inversely correlates with HbA1c levels in individuals with type 2 diabetes

(2019) Flore Sinturel et al.   DIABETOLOGIA

Off the Clock: From Circadian Disruption to Metabolic Disease

(2019) Eleonore Maury   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Melatonin in Alzheimer’s Disease: A Latent Endogenous Regulator of Neurogenesis to Mitigate Alzheimer’s Neuropathology

(2019) Md. Farhad Hossain et al.   MOLECULAR NEUROBIOLOGY

Differential Effects of Alternate‐Day Fasting Versus Daily Calorie Restriction on Insulin Resistance

(2019) Kelsey Gabel et al.   Obesity

Pharmacological activation of the nuclear receptor REV-ERB reverses cognitive deficits and reduces amyloid-β burden in a mouse model of Alzheimer’s disease

(2019) Deborah A. Roby et al.   PLoS One

Association between diabetes and mood disorders and the potential use of anti-hyperglycemic agents as antidepressants

(2019) Ruth B. Grigolon et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Bedroom lighting environment and incident diabetes mellitus: a longitudinal study of the HEIJO-KYO cohort

(2019) Kenji Obayashi et al.   SLEEP MEDICINE

The diurnal variation of bone formation is attenuated in adult patients with type 2 diabetes

(2019) Katrine Hygum et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Chronotherapeutic effect of orexin antagonists on glucose metabolism in diabetic mice

(2019) Kanta Kon et al.   JOURNAL OF ENDOCRINOLOGY

Nutrients in the Prevention of Alzheimer’s Disease

(2019) Anna Laura Cremonini et al.   Oxidative Medicine and Cellular Longevity

Correlation between inflammatory markers and impaired circadian clock gene expression in type 2 diabetes mellitus

(2019) Rongguo Yu et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Alzheimer's disease-associated tau alters Drosophila circadian activity, sleep and clock neuron electrophysiology

(2019) Edgar Buhl et al.   NEUROBIOLOGY OF DISEASE

Light therapy with boxes or glasses to counteract effects of acute sleep deprivation

(2019) Henri Comtet et al.   Scientific Reports

Cognitive impairment with diabetes mellitus and metabolic disease: innovative insights with the mechanistic target of rapamycin and circadian clock gene pathways

(2019) Kenneth Maiese   Expert Review of Clinical Pharmacology

Pharmacological activation of REV-ERBα represses LPS-induced microglial activation through the NF-κB pathway

(2018) Dong-kai Guo et al.   ACTA PHARMACOLOGICA SINICA

Intermittent fasting protects against the deterioration of cognitive function, energy metabolism and dyslipidemia in Alzheimer’s disease-induced estrogen deficient rats

(2018) Bae Kun Shin et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Regulation of amyloid-β dynamics and pathology by the circadian clock

(2018) Geraldine J. Kress et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Circadian regulation of glucose, lipid, and energy metabolism in humans

(2018) Eleonora Poggiogalle et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Cognitive decline and dementia in diabetes mellitus: mechanisms and clinical implications

(2018) Geert Jan Biessels et al.   Nature Reviews Endocrinology

Chronopathophysiological implications of orexin in sleep disturbances and lifestyle-related disorders

(2018) Hiroshi Tsuneki et al.   PHARMACOLOGY & THERAPEUTICS

Circadian Etiology of Type 2 Diabetes Mellitus

(2018) Naureen Javeed et al.   PHYSIOLOGY

Circadian control of BDNF-mediated Nrf2 activation in astrocytes protects dopaminergic neurons from ferroptosis

(2018) Tetsuro Ishii et al.   FREE RADICAL BIOLOGY AND MEDICINE

Stress-Induced Cytokines and Neuronal Dysfunction in Alzheimer's Disease

(2018) Serafino Ricci et al.   JOURNAL OF ALZHEIMERS DISEASE

Circadian disruption and human health: a bidirectional relationship

(2018) Sabra M. Abbott et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Calorie restriction reprograms diurnal rhythms in protein translation to regulate metabolism

(2018) Kuldeep Makwana et al.   FASEB JOURNAL

Antidepressant agomelatine attenuates behavioral deficits and concomitant pathology observed in streptozotocin-induced model of Alzheimer's disease in male rats

(2018) Kalina Ilieva et al.   HORMONES AND BEHAVIOR

A Novel Diabetic Mouse Model for Real-Time Monitoring of Clock Gene Oscillation and Blood Pressure Circadian Rhythm

(2018) Tianfei Hou et al.   JOURNAL OF BIOLOGICAL RHYTHMS

Circadian clocks and insulin resistance

(2018) Dirk Jan Stenvers et al.   Nature Reviews Endocrinology

Circadian blueprint of metabolic pathways in the brain

(2018) Carolina Magdalen Greco et al.   NATURE REVIEWS NEUROSCIENCE

Diabetes and Alzheimer’s Disease: A Link not as Simple as it Seems

(2018) Isabel H. Salas et al.   NEUROCHEMICAL RESEARCH

Timing Matters: Circadian Effects on Energy Homeostasis and Alzheimer’s Disease

(2018) Aline Loehfelm et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Timing of Food Intake: Identifying Contributing Factors to Design Effective Interventions

(2018) Hassan S Dashti et al.   Advances in Nutrition

Does the diurnal cycle of cortisol explain the relationship between physical performance and cognitive function in older adults?

(2017) B. Dijckmans et al.   European Review of Aging and Physical Activity

Oxidative Stress, Synaptic Dysfunction, and Alzheimer’s Disease

(2017) Eric Tönnies et al.   JOURNAL OF ALZHEIMERS DISEASE

Neurodegeneration and the Circadian Clock

(2017) Suzanne Hood et al.   Frontiers in Aging Neuroscience

Circadian phenotyping of obese and diabetic db/db mice

(2016) Edith Grosbellet et al.   BIOCHIMIE

Circadian Rhythms of Carbohydrate Metabolism in Women with Different Types of Obesity

(2016) B. B. Pinkhasov et al.   BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE

The Small Molecule Nobiletin Targets the Molecular Oscillator to Enhance Circadian Rhythms and Protect against Metabolic Syndrome

(2016) Baokun He et al.   Cell Metabolism

Physical Activity/Exercise and Diabetes: A Position Statement of the American Diabetes Association

(2016) Sheri R. Colberg et al.   DIABETES CARE

Chronomedicine and type 2 diabetes: shining some light on melatonin

(2016) Andrew C. Forrestel et al.   DIABETOLOGIA

Timed Inhibition of Orexin System by Suvorexant Improved Sleep and Glucose Metabolism in Type 2 Diabetic db/db Mice

(2016) Hiroshi Tsuneki et al.   ENDOCRINOLOGY

Adverse Impact of Sleep Restriction and Circadian Misalignment on Autonomic Function in Healthy Young AdultsNovelty and Significance

(2016) Daniela Grimaldi et al.   HYPERTENSION

Effects of the Internal Circadian System and Circadian Misalignment on Glucose Tolerance in Chronic Shift Workers

(2016) Christopher J. Morris et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The mammalian circadian clock and its entrainment by stress and exercise

(2016) Yu Tahara et al.   Journal of Physiological Sciences

Alzheimer's disease

(2016) Philip Scheltens et al.   LANCET

No diurnal variation of classical and candidate biomarkers of Alzheimer’s disease in CSF

(2016) Claudia Cicognola et al.   Molecular Neurodegeneration

Diabetes mellitus statistics on prevalence and mortality: facts and fallacies

(2016) Paul Zimmet et al.   Nature Reviews Endocrinology

Long-term cortisol measures predict Alzheimer disease risk

(2016) Gilda E. Ennis et al.   NEUROLOGY

Scheduled evening sleep and enhanced lighting improve adaptation to night shift work in older adults

(2016) Evan D Chinoy et al.   OCCUPATIONAL AND ENVIRONMENTAL MEDICINE

Mechanisms linking circadian clocks, sleep, and neurodegeneration

(2016) Erik S. Musiek et al.   SCIENCE

Circadian System and Glucose Metabolism: Implications for Physiology and Disease

(2016) Jingyi Qian et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Orexin signaling regulates both the hippocampal clock and the circadian oscillation of Alzheimer’s disease-risk genes

(2016) Zhixiong Ma et al.   Scientific Reports

Degeneration and energy shortage in the suprachiasmatic nucleus underlies the circadian rhythm disturbance in ApoE−/− mice: implications for Alzheimer’s disease

(2016) Lan Zhou et al.   Scientific Reports

A review of dopamine agonist therapy in type 2 diabetes and effects on cardio-metabolic parameters

(2016) E.M. Lamos et al.   Primary Care Diabetes

Time for Food: The Intimate Interplay between Nutrition, Metabolism, and the Circadian Clock

(2015) Gad Asher et al.   CELL

Hepatic Bmal1 Regulates Rhythmic Mitochondrial Dynamics and Promotes Metabolic Fitness

(2015) David Jacobi et al.   Cell Metabolism

Aligning Work and Circadian Time in Shift Workers Improves Sleep and Reduces Circadian Disruption

(2015) Céline Vetter et al.   CURRENT BIOLOGY

Neuroinflammation in Alzheimer's disease

(2015) Michael T Heneka et al.   LANCET NEUROLOGY

Electric light, particularly at night, disrupts human circadian rhythmicity: is that a problem?

(2015) R. G. Stevens et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Endogenous circadian system and circadian misalignment impact glucose tolerance via separate mechanisms in humans

(2015) Christopher J. Morris et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Disruption of Daily Rhythms by High-Fat Diet Is Reversible

(2015) Katrina L. Branecky et al.   PLoS One

Differential regulation of circadian melatonin rhythm and sleep-wake cycle by bright lights and nonphotic time cues in humans

(2014) Yujiro Yamanaka et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Hypothalamic Orexin Prevents Hepatic Insulin Resistance via Daily Bidirectional Regulation of Autonomic Nervous System in Mice

(2014) Hiroshi Tsuneki et al.   DIABETES

Circadian Secretion of the Intestinal Hormone GLP-1 by the Rodent L Cell

(2014) Manuel Gil-Lozano et al.   DIABETES

Potential role of orexin and sleep modulation in the pathogenesis of Alzheimer’s disease

(2014) Jee Hoon Roh et al.   JOURNAL OF EXPERIMENTAL MEDICINE

'The clocks that time us'—circadian rhythms in neurodegenerative disorders

(2014) Aleksandar Videnovic et al.   Nature Reviews Neurology

Sleep deprivation impairs memory, tau metabolism, and synaptic integrity of a mouse model of Alzheimer's disease with plaques and tangles

(2014) Antonio Di Meco et al.   NEUROBIOLOGY OF AGING

Add-on prolonged-release melatonin for cognitive function and sleep in mild to moderate Alzheimer’s disease: a 6-month, randomized, placebo-controlled, multicenter trial

(2014) Moshe Laudon et al.   Clinical Interventions in Aging

The global prevalence of dementia: A systematic review and metaanalysis

(2013) Martin Prince et al.   Alzheimers & Dementia

Chronic mild sleep restriction accentuates contextual memory impairments, and accumulations of cortical Aβ and pTau in a mouse model of Alzheimer's disease

(2013) Sarah M. Rothman et al.   BRAIN RESEARCH

Circadian-clock system in mouse liver affected by insulin resistance

(2013) Shu-Chuan Yang et al.   CHRONOBIOLOGY INTERNATIONAL

Entrainment of the Human Circadian Clock to the Natural Light-Dark Cycle

(2013) Kenneth P. Wright et al.   CURRENT BIOLOGY

High-fat diet acutely affects circadian organisation and eating behavior

(2013) Julie S. Pendergast et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Detrimental effects of constant light exposure and high-fat diet on circadian energy metabolism and insulin sensitivity

(2013) Claudia P. Coomans et al.   FASEB JOURNAL

Melatonin in Alzheimer’s Disease

(2013) Li Lin et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Behavioral therapy reverses circadian deficits in a transgenic mouse model of Huntington's disease

(2013) Marc Cuesta et al.   NEUROBIOLOGY OF DISEASE

Central and Peripheral Circadian Clocks in Mammals

(2012) Jennifer A. Mohawk et al.   Annual Review of Neuroscience

Circadian Rhythm Connections to Oxidative Stress: Implications for Human Health

(2012) Melissa Wilking et al.   ANTIOXIDANTS & REDOX SIGNALING

The Circadian System in Alzheimer’s Disease: Disturbances, Mechanisms, and Opportunities

(2012) Andrew N. Coogan et al.   BIOLOGICAL PSYCHIATRY

Time-Restricted Feeding without Reducing Caloric Intake Prevents Metabolic Diseases in Mice Fed a High-Fat Diet

(2012) Megumi Hatori et al.   Cell Metabolism

Biological Rhythms During Residence in Polar Regions

(2012) Josephine Arendt   CHRONOBIOLOGY INTERNATIONAL

A Circadian Rhythm in Heart Rate Variability Contributes to the Increased Cardiac Sympathovagal Response to Awakening in the Morning

(2012) Philippe Boudreau et al.   CHRONOBIOLOGY INTERNATIONAL

Effect of time of day and fasting duration on measures of glycaemia: analysis from the Whitehall II Study

(2012) A. Hulmán et al.   DIABETOLOGIA

Regulation of core clock genes in human islets

(2012) Jelena A. Stamenkovic et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Timing to Perfection: The Biology of Central and Peripheral Circadian Clocks

(2012) Urs Albrecht   NEURON

Altered clock gene expression and vascular smooth muscle diurnal contractile variations in type 2 diabetic db/db mice

(2011) Wen Su et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Metformin opposes impaired AMPK and SIRT1 function and deleterious changes in core clock protein expression in white adipose tissue of genetically-obese db/db mice

(2011) P. W. Caton et al.   DIABETES OBESITY & METABOLISM

Flattened Circadian Cortisol Rhythm in Type 2 Diabetes

(2011) F. Lederbogen et al.   EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES

Circadian Clock Gene Expression in Brain Regions of Alzheimer ’s Disease Patients and Control Subjects

(2011) Nicolas Cermakian et al.   JOURNAL OF BIOLOGICAL RHYTHMS

Circadian rhythms, sleep, and metabolism

(2011) Wenyu Huang et al.   JOURNAL OF CLINICAL INVESTIGATION

Circadian system, sleep and endocrinology

(2011) Christopher J. Morris et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Disruption of circadian clocks has ramifications for metabolism, brain, and behavior

(2011) I. N. Karatsoreos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Loss of Bmal1 leads to uncoupling and impaired glucose-stimulated insulin secretion in β-cells

(2011) Jeongkyung Lee et al.   Islets

Rotating Night Shift Work and Risk of Type 2 Diabetes: Two Prospective Cohort Studies in Women

(2011) An Pan et al.   PLOS MEDICINE

Efficacy and safety of prolonged-release melatonin in insomnia patients with diabetes: a randomized, double-blind, crossover study

(2011) Nava Zisapel et al.   Diabetes Metabolic Syndrome and Obesity-Targets and Therapy

Characterization of the 3xTg-AD mouse model of Alzheimer's disease: Part 1. Circadian changes

(2010) Roxanne Sterniczuk et al.   BRAIN RESEARCH

LIFESPAN DAILY LOCOMOTOR ACTIVITY RHYTHMS IN A MOUSE MODEL OF AMYLOID-INDUCED NEUROPATHOLOGY

(2010) Michael R. Gorman et al.   CHRONOBIOLOGY INTERNATIONAL

Bromocriptine: old drug, new formulation and new indication

(2010) R. I. G. Holt et al.   DIABETES OBESITY & METABOLISM

Exposure to Room Light before Bedtime Suppresses Melatonin Onset and Shortens Melatonin Duration in Humans

(2010) Joshua J. Gooley et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Cryptochrome mediates circadian regulation of cAMP signaling and hepatic gluconeogenesis

(2010) Eric E Zhang et al.   NATURE MEDICINE

Physical exercise accelerates reentrainment of human sleep-wake cycle but not of plasma melatonin rhythm to 8-h phase-advanced sleep schedule

(2009) Yujiro Yamanaka et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Effects of Sleep Fragmentation on Glucose Metabolism in Normal Subjects

(2009) Katherine A. Stamatakis et al.   CHEST

Cardiovascular and autonomic phenotype ofdb/dbdiabetic mice

(2009) Danielle Senador et al.   EXPERIMENTAL PHYSIOLOGY

Abnormal expressions of circadian-clock and circadian clock-controlled genes in the livers and kidneys of long-term, high-fat-diet-treated mice

(2009) M-C Hsieh et al.   INTERNATIONAL JOURNAL OF OBESITY

Effects of acute and chronic STZ-induced diabetes on clock gene expression and feeding in the gastrointestinal tract

(2009) Jonathon Bostwick et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Orexin/Hypocretin: A Neuropeptide at the Interface of Sleep, Energy Homeostasis, and Reward System

(2009) N. Tsujino et al.   PHARMACOLOGICAL REVIEWS

Reduction of scale invariance of activity fluctuations with aging and Alzheimer's disease: Involvement of the circadian pacemaker

(2009) Kun Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Amyloid-  Dynamics Are Regulated by Orexin and the Sleep-Wake Cycle

(2009) J.-E. Kang et al.   SCIENCE

Hypertension and disrupted blood pressure circadian rhythm in Type 2 diabetic db/db mice

(2008) Wen Su et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Sleep-wake regulation is altered in leptin-resistant (db/db) genetically obese and diabetic mice

(2008) A. D. Laposky et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

The nuclear receptors Rev-erbs and RORs integrate circadian rhythms and metabolism

(2008) Hélène Duez et al.   Diabetes & Vascular Disease Research

Clock gene expression in peripheral leucocytes of patients with type 2 diabetes

(2008) H. Ando et al.   DIABETOLOGIA

Physiological significance of a peripheral tissue circadian clock

(2008) K. A. Lamia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA