标题
Mechanisms linking circadian clocks, sleep, and neurodegeneration
作者
关键词
-
出版物
SCIENCE
Volume 354, Issue 6315, Pages 1004-1008
出版商
American Association for the Advancement of Science (AAAS)
发表日期
2016-11-25
DOI
10.1126/science.aah4968
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Altered CSF Orexin and α-Synuclein Levels in Dementia Patients
- (2018) Malin Wennström et al. JOURNAL OF ALZHEIMERS DISEASE
- The circadian clock regulates autophagy directly through the nuclear hormone receptor Nr1d1/Rev-erbα and indirectly via Cebpb/(C/ebpβ) in zebrafish
- (2016) Guodong Huang et al. Autophagy
- Timing of expression of the core clock gene Bmal1 influences its effects on aging and survival
- (2016) Guangrui Yang et al. Science Translational Medicine
- Orexin-A is Associated with Increases in Cerebrospinal Fluid Phosphorylated-Tau in Cognitively Normal Elderly Subjects
- (2016) Ricardo S. Osorio et al. SLEEP
- Orexin-A is Associated with Increases in Cerebrospinal Fluid Phosphorylated-Tau in Cognitively Normal Elderly Subjects
- (2016) Ricardo S. Osorio et al. SLEEP
- Premature aging of the hippocampal neurogenic niche in adult Bmal1‐ deficient mice
- (2015) Amira A. H. Ali et al. Aging-US
- Self-reported sleep disturbance is associated with Alzheimer's disease risk in men
- (2015) Christian Benedict et al. Alzheimers & Dementia
- Sleep deficits but no metabolic deficits in premanifest Huntington's disease
- (2015) Alpar S. Lazar et al. ANNALS OF NEUROLOGY
- Suprachiasmatic neuron numbers and rest-activity circadian rhythms in older humans
- (2015) Joshua L. Wang et al. ANNALS OF NEUROLOGY
- Microglia inflammatory responses are controlled by an intrinsic circadian clock
- (2015) Laura K. Fonken et al. BRAIN BEHAVIOR AND IMMUNITY
- Association between ARNTL (BMAL1) rs2278749 polymorphism T >C and susceptibility to Alzheimer disease in a Chinese population
- (2015) Q. Chen et al. GENETICS AND MOLECULAR RESEARCH
- Acute Sleep Loss Induces Tissue-Specific Epigenetic and Transcriptional Alterations to Circadian Clock Genes in Men
- (2015) Jonathan Cedernaes et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Aβ-induced degradation of BMAL1 and CBP leads to circadian rhythm disruption in Alzheimer’s disease
- (2015) Hyundong Song et al. Molecular Neurodegeneration
- Three dimensions of the amyloid hypothesis: time, space and 'wingmen'
- (2015) Erik S Musiek et al. NATURE NEUROSCIENCE
- β-amyloid disrupts human NREM slow waves and related hippocampus-dependent memory consolidation
- (2015) Bryce A Mander et al. NATURE NEUROSCIENCE
- Circadian control of innate immunity in macrophages by miR-155 targetingBmal1
- (2015) Anne M. Curtis et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- In Vivo Imaging of the Central and Peripheral Effects of Sleep Deprivation and Suprachiasmatic Nuclei Lesion on PERIOD-2 Protein in Mice
- (2015) Thomas Curie et al. SLEEP
- Association of ARNTL and PER1 genes with Parkinson's disease: a case-control study of Han Chinese
- (2015) Zhuqin Gu et al. Scientific Reports
- Misaligned feeding impairs memories
- (2015) Dawn H Loh et al. eLife
- In Vivo Imaging of the Central and Peripheral Effects of Sleep Deprivation and Suprachiasmatic Nuclei Lesion on PERIOD-2 Protein in Mice
- (2015) Thomas Curie et al. SLEEP
- A time to remember: The role of circadian clocks in learning and memory.
- (2014) Benjamin L. Smarr et al. BEHAVIORAL NEUROSCIENCE
- Circadian modulation of proteasome activities and removal of carbonylated proteins
- (2014) Audrey Desvergne et al. FREE RADICAL BIOLOGY AND MEDICINE
- Potential role of orexin and sleep modulation in the pathogenesis of Alzheimer’s disease
- (2014) Jee Hoon Roh et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Extended Wakefulness: Compromised Metabolics in and Degeneration of Locus Ceruleus Neurons
- (2014) J. Zhang et al. JOURNAL OF NEUROSCIENCE
- 'The clocks that time us'—circadian rhythms in neurodegenerative disorders
- (2014) Aleksandar Videnovic et al. Nature Reviews Neurology
- Sleep deprivation impairs memory, tau metabolism, and synaptic integrity of a mouse model of Alzheimer's disease with plaques and tangles
- (2014) Antonio Di Meco et al. NEUROBIOLOGY OF AGING
- Sleep and the Price of Plasticity: From Synaptic and Cellular Homeostasis to Memory Consolidation and Integration
- (2014) Giulio Tononi et al. NEURON
- Survival of Adult Generated Hippocampal Neurons Is Altered in Circadian Arrhythmic Mice
- (2014) Brooke D. Rakai et al. PLoS One
- A circadian gene expression atlas in mammals: Implications for biology and medicine
- (2014) Ray Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Acute Sleep Deprivation Increases Serum Levels of Neuron-Specific Enolase (NSE) and S100 Calcium Binding Protein B (S-100B) in Healthy Young Men
- (2014) Christian Benedict et al. SLEEP
- Circadian Melatonin Rhythm and Excessive Daytime Sleepiness in Parkinson Disease
- (2014) Aleksandar Videnovic et al. JAMA Neurology
- Sleep and Circadian Rhythm Regulation in Early Parkinson Disease
- (2014) David P. Breen et al. JAMA Neurology
- Polymorphism of CLOCK Gene rs 4580704 C>G Is Associated with Susceptibility of Alzheimer’s Disease in a Chinese Population
- (2013) Hai-feng Chen et al. ARCHIVES OF MEDICAL RESEARCH
- Chronic mild sleep restriction accentuates contextual memory impairments, and accumulations of cortical Aβ and pTau in a mouse model of Alzheimer's disease
- (2013) Sarah M. Rothman et al. BRAIN RESEARCH
- Homeostasis in Intestinal Epithelium Is Orchestrated by the Circadian Clock and Microbiota Cues Transduced by TLRs
- (2013) Atish Mukherji et al. CELL
- SIRT1 Mediates Central Circadian Control in the SCN by a Mechanism that Decays with Aging
- (2013) Hung-Chun Chang et al. CELL
- Sleep Disturbance is Associated with Incident Dementia and Mortality
- (2013) Roxanne Sterniczuk et al. Current Alzheimer Research
- Circadian clock proteins regulate neuronal redox homeostasis and neurodegeneration
- (2013) Erik S. Musiek et al. JOURNAL OF CLINICAL INVESTIGATION
- Circadian Gene Bmal1 Regulates Diurnal Oscillations of Ly6Chi Inflammatory Monocytes
- (2013) K. D. Nguyen et al. SCIENCE
- Sleep Drives Metabolite Clearance from the Adult Brain
- (2013) L. Xie et al. SCIENCE
- Sleep Fragmentation and the Risk of Incident Alzheimer's Disease and Cognitive Decline in Older Persons
- (2013) Andrew S. P. Lim et al. SLEEP
- Delayed emergence of a parkinsonian disorder or dementia in 81% of older men initially diagnosed with idiopathic rapid eye movement sleep behavior disorder: a 16-year update on a previously reported series
- (2013) Carlos H. Schenck et al. SLEEP MEDICINE
- The intrinsic microglial molecular clock controls synaptic strength via the circadian expression of cathepsin S
- (2013) Yoshinori Hayashi et al. Scientific Reports
- The Circadian Molecular Clock Regulates Adult Hippocampal Neurogenesis by Controlling the Timing of Cell-Cycle Entry and Exit
- (2013) Pascale Bouchard-Cannon et al. Cell Reports
- Sleep Quality and Preclinical Alzheimer Disease
- (2013) Yo-El S. Ju et al. JAMA Neurology
- Central and Peripheral Circadian Clocks in Mammals
- (2012) Jennifer A. Mohawk et al. Annual Review of Neuroscience
- Circadian Oscillations of Molecular Clock Components in the Cerebellar Cortex of the Rat
- (2012) Martin F. Rath et al. CHRONOBIOLOGY INTERNATIONAL
- Circadian Dbp Transcription Relies on Highly Dynamic BMAL1-CLOCK Interaction with E Boxes and Requires the Proteasome
- (2012) Markus Stratmann et al. MOLECULAR CELL
- Peroxiredoxins are conserved markers of circadian rhythms
- (2012) Rachel S. Edgar et al. NATURE
- Circadian Regulation of Glutathione Levels and Biosynthesis in Drosophila melanogaster
- (2012) Laura M. Beaver et al. PLoS One
- Circadian Rhythm of Redox State Regulates Excitability in Suprachiasmatic Nucleus Neurons
- (2012) T. A. Wang et al. SCIENCE
- A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid
- (2012) J. J. Iliff et al. Science Translational Medicine
- Disruption of the Sleep-Wake Cycle and Diurnal Fluctuation of -Amyloid in Mice with Alzheimer's Disease Pathology
- (2012) J. H. Roh et al. Science Translational Medicine
- Circadian activity rhythms and risk of incident dementia and mild cognitive impairment in older women
- (2011) Gregory J. Tranah et al. ANNALS OF NEUROLOGY
- Effects of Age and Amyloid Deposition on Aβ Dynamics in the Human Central Nervous System
- (2011) Yafei Huang ARCHIVES OF NEUROLOGY
- Circadian clock protein BMAL1 regulates cellular senescence in vivo
- (2011) Rohini V. Khapre et al. CELL CYCLE
- Temporal orchestration of circadian autophagy rhythm by C/EBPβ
- (2011) Di Ma et al. EMBO JOURNAL
- Circadian dysfunction in a mouse model of Parkinson's disease
- (2011) Takashi Kudo et al. EXPERIMENTAL NEUROLOGY
- Circadian Clock Gene Expression in Brain Regions of Alzheimer ’s Disease Patients and Control Subjects
- (2011) Nicolas Cermakian et al. JOURNAL OF BIOLOGICAL RHYTHMS
- Age-Related Decline in Circadian Output
- (2011) T. J. Nakamura et al. JOURNAL OF NEUROSCIENCE
- Sleep Loss Reduces the DNA-Binding of BMAL1, CLOCK, and NPAS2 to Specific Clock Genes in the Mouse Cerebral Cortex
- (2011) Valérie Mongrain et al. PLoS One
- The nuclear receptor REV-ERB mediates circadian regulation of innate immunity through selective regulation of inflammatory cytokines
- (2011) J. E. Gibbs et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Disruption of circadian clocks has ramifications for metabolism, brain, and behavior
- (2011) I. N. Karatsoreos et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Characterization of the 3xTg-AD mouse model of Alzheimer's disease: Part 1. Circadian changes
- (2010) Roxanne Sterniczuk et al. BRAIN RESEARCH
- Impact of aging on diurnal expression patterns of CLOCK and BMAL1 in the mouse brain
- (2010) Cathy A. Wyse et al. BRAIN RESEARCH
- Dysfunctions in circadian behavior and physiology in mouse models of Huntington's disease
- (2010) Takashi Kudo et al. EXPERIMENTAL NEUROLOGY
- Dysregulation of Inflammatory Responses by Chronic Circadian Disruption
- (2010) O. Castanon-Cervantes et al. JOURNAL OF IMMUNOLOGY
- Disruption of Peripheral Circadian Timekeeping in a Mouse Model of Huntington's Disease and Its Restoration by Temporally Scheduled Feeding
- (2010) E. S. Maywood et al. JOURNAL OF NEUROSCIENCE
- Experimental ‘Jet Lag’ Inhibits Adult Neurogenesis and Produces Long-Term Cognitive Deficits in Female Hamsters
- (2010) Erin M. Gibson et al. PLoS One
- Circadian Integration of Metabolism and Energetics
- (2010) J. Bass et al. SCIENCE
- Expression of clock genesPer1andBmal1in total leukocytes in health and Parkinson’s disease
- (2009) Y. Cai et al. EUROPEAN JOURNAL OF NEUROLOGY
- A circadian clock in macrophages controls inflammatory immune responses
- (2009) Maren Keller et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Circadian Control of the NAD+ Salvage Pathway by CLOCK-SIRT1
- (2009) Y. Nakahata et al. SCIENCE
- Amyloid- Dynamics Are Regulated by Orexin and the Sleep-Wake Cycle
- (2009) J.-E. Kang et al. SCIENCE
- Circadian Clock Feedback Cycle Through NAMPT-Mediated NAD+ Biosynthesis
- (2009) K. M. Ramsey et al. SCIENCE
- Differential display of DNA-binding proteins reveals heat-shock factor 1 as a circadian transcription factor
- (2008) H. Reinke et al. GENES & DEVELOPMENT
- Effect of Bright Light and Melatonin on Cognitive and Noncognitive Function in Elderly Residents of Group Care Facilities
- (2008) Rixt F. Riemersma-van der Lek JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Aging Impairs the Unfolded Protein Response to Sleep Deprivation and Leads to Proapoptotic Signaling
- (2008) N. Naidoo et al. JOURNAL OF NEUROSCIENCE
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started