Pharmacological activation of the nuclear receptor REV-ERB reverses cognitive deficits and reduces amyloid-β burden in a mouse model of Alzheimer’s disease

Peripheral Administration of Antisense Oligonucleotides Targeting the Amyloid-β Protein Precursor Reverses AβPP and LRP-1 Overexpression in the Aged SAMP8 Mouse Brain

(2018) Michelle A. Erickson et al.   JOURNAL OF ALZHEIMERS DISEASE

Mouse Models of Alzheimer’s Disease

(2017) Gisela Esquerda-Canals et al.   JOURNAL OF ALZHEIMERS DISEASE

Neurotoxic reactive astrocytes are induced by activated microglia

(2017) Shane A. Liddelow et al.   NATURE

The roles of class I histone deacetylases (HDACs) in memory, learning, and executive cognitive functions: A review

(2017) Claudia Schmauss   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Alzheimer’s Disease: From Genetic Variants to the Distinct Pathological Mechanisms

(2017) Qiying Sun et al.   Frontiers in Molecular Neuroscience

A Physiological Role for Amyloid-β Protein: Enhancement of Learning and Memory

(2017) John E. Morley et al.   JOURNAL OF ALZHEIMERS DISEASE

Early Amyloid Accumulation in the Hippocampus of SAMP8 Mice

(2017) Jaume del Valle et al.   JOURNAL OF ALZHEIMERS DISEASE

Astrocyte Regulation of Blood Flow in the Brain

(2015) Brian A. MacVicar et al.   Cold Spring Harbor Perspectives in Biology

Clusterin Seals the Ocular Surface Barrier in Mouse Dry Eye

(2015) Aditi Bauskar et al.   PLoS One

Spatial and Working Memory Is Linked to Spine Density and Mushroom Spines

(2015) Rasha Refaat Mahmmoud et al.   PLoS One

Early alterations in energy metabolism in the hippocampus of APPswe/PS1dE9 mouse model of Alzheimer's disease

(2014) Ignacio Pedrós et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Neuroinflammation in Alzheimer’s Disease: from Pathogenesis to a Therapeutic Target

(2014) Sanjay W. Pimplikar   JOURNAL OF CLINICAL IMMUNOLOGY

Amyloid-Beta: A Crucial Factor in Alzheimer's Disease

(2014) Saeed Sadigh-Eteghad et al.   MEDICAL PRINCIPLES AND PRACTICE

Behavioral Changes and Dopaminergic Dysregulation in Mice Lacking the Nuclear Receptor Rev-erbα

(2014) Jennifer Jager et al.   MOLECULAR ENDOCRINOLOGY

The Intersection of Amyloid Beta and Tau at Synapses in Alzheimer’s Disease

(2014) Tara L. Spires-Jones et al.   NEURON

The Nuclear Receptor REV-ERBα Regulates Fabp7 and Modulates Adult Hippocampal Neurogenesis

(2014) Anna Schnell et al.   PLoS One

Pharmacological targeting of the mammalian clock regulates sleep architecture and emotional behaviour

(2014) Subhashis Banerjee et al.   Nature Communications

Antisense oligonucleotide against GSK-3β in brain of SAMP8 mice improves learning and memory and decreases oxidative stress: Involvement of transcription factor Nrf2 and implications for Alzheimer disease

(2013) Susan A. Farr et al.   FREE RADICAL BIOLOGY AND MEDICINE

SAMP8 mice have altered hippocampal gene expression in long term potentiation, phosphatidylinositol signaling, and endocytosis pathways

(2013) Harvey J. Armbrecht et al.   NEUROBIOLOGY OF AGING

Heterogeneity of reactive astrocytes

(2013) Mark A. Anderson et al.   NEUROSCIENCE LETTERS

Neurotoxicity of Amyloid  -Protein: Synaptic and Network Dysfunction

(2013) L. Mucke et al.   Cold Spring Harbor Perspectives in Medicine

White matter atrophy in Alzheimer's disease variants

(2012) Raffaella Migliaccio et al.   Alzheimers & Dementia

Genomic Analysis of Reactive Astrogliosis

(2012) J. L. Zamanian et al.   JOURNAL OF NEUROSCIENCE

Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists

(2012) Laura A. Solt et al.   NATURE

Regulation of circadian behaviour and metabolism by REV-ERB-α and REV-ERB-β

(2012) Han Cho et al.   NATURE

Amyloid Precursor Protein Processing and Alzheimer's Disease

(2011) Richard J. O'Brien et al.   Annual Review of Neuroscience

A circadian clock in hippocampus is regulated by interaction between oligophrenin-1 and Rev-erbα

(2011) Pamela Valnegri et al.   NATURE NEUROSCIENCE

Serial CSF sampling in Alzheimer's disease: specific versus non-specific markers

(2011) Maartje I. Kester et al.   NEUROBIOLOGY OF AGING

Cerebral Amyloid Angiopathy, Blood-Brain Barrier Disruption and Amyloid Accumulation in SAMP8 Mice

(2011) Jaume del Valle et al.   Neurodegenerative Diseases

Direct Regulation of CLOCK Expression by REV-ERB

(2011) Christine Crumbley et al.   PLoS One

Integrated Brain Circuits: Astrocytic Networks Modulate Neuronal Activity and Behavior

(2010) Michael M. Halassa et al.   Annual Review of Physiology

Regulation of Adipogenesis by Natural and Synthetic REV-ERB Ligands

(2010) Naresh Kumar et al.   ENDOCRINOLOGY

Microtubule destruction induces tau liberation and its subsequent phosphorylation

(2010) Tomohiro Miyasaka et al.   FEBS LETTERS

Characterization of the Core Mammalian Clock Component, NPAS2, as a REV-ERBα/RORα Target Gene

(2010) Christine Crumbley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neural mechanisms of ageing and cognitive decline

(2010) Nicholas A. Bishop et al.   NATURE

Glial and neuronal control of brain blood flow

(2010) David Attwell et al.   NATURE

Rev-erb-α: an integrator of circadian rhythms and metabolism

(2009) Hélène Duez et al.   JOURNAL OF APPLIED PHYSIOLOGY

When does age-related cognitive decline begin?

(2009) Timothy A. Salthouse   NEUROBIOLOGY OF AGING

Down-regulation of aminolevulinate synthase, the rate-limiting enzyme for heme biosynthesis in Alzheimer's disease

(2009) Barney E. Dwyer et al.   NEUROSCIENCE LETTERS

Nuclear Hormone Receptors for Heme: REV-ERBα and REV-ERBβ Are Ligand-Regulated Components of the Mammalian Clock

(2008) Thomas P. Burris   MOLECULAR ENDOCRINOLOGY