Adaptive homeostasis and the p53 isoform network

Distinct mechanisms control genome recognition by p53 at its target genes linked to different cell fates

(2021) Marina Farkas et al.   Nature Communications

Decreased p53 is associated with a decline in asymmetric stem cell self‐renewal in aged human epidermis

(2021) Alexandra Charruyer et al.   AGING CELL

Porcine model elucidates function of p53 isoform in carcinogenesis and reveals novel circTP53 RNA

(2021) Guanglin Niu et al.   ONCOGENE

Loss-of-function of p53 isoform Δ113p53 accelerates brain aging in zebrafish

(2021) Ting Zhao et al.   Cell Death & Disease

The balance between p53 isoforms modulates the efficiency of HIV-1 infection in macrophages

(2021) Yann Breton et al.   JOURNAL OF VIROLOGY

The Δ40p53 isoform inhibits p53-dependent eRNA transcription and enables regulation by signal-specific transcription factors during p53 activation

(2021) Cecilia B. Levandowski et al.   PLOS BIOLOGY

Δ133p53α enhances metabolic and cellular fitness of TCR-engineered T cells and promotes superior antitumor immunity

(2021) Kevin Jan Legscha et al.   Journal for ImmunoTherapy of Cancer

AMP-Activated Protein Kinase Restricts Zika Virus Replication in Endothelial Cells by Potentiating Innate Antiviral Responses and Inhibiting Glycolysis

(2020) Sneha Singh et al.   JOURNAL OF IMMUNOLOGY

P53 vs NF-κB: the role of nuclear factor-kappa B in the regulation of p53 activity and vice versa

(2020) Giovanna Carrà et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Reactive oxygen species (ROS) as pleiotropic physiological signalling agents

(2020) Helmut Sies et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Oncogenic human herpesvirus hijacks proline metabolism for tumorigenesis

(2020) Un Yung Choi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of p53 in the Regulation of Cellular Senescence

(2020) Mahmut Mijit et al.   Biomolecules

Enhancer RNAs are an important regulatory layer of the epigenome

(2020) Vittorio Sartorelli et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

p53 isoform Δ113p53 promotes zebrafish heart regeneration by maintaining redox homeostasis

(2020) Shengfan Ye et al.   Cell Death & Disease

Human Endogenous Retrovirus K (HML-2) in Health and Disease

(2020) Bei Xue et al.   Frontiers in Microbiology

Senescence and Host–Pathogen Interactions

(2020) Daniel Humphreys et al.   Cells

HIV-1 Nef promotes ubiquitination and proteasomal degradation of p53 tumor suppressor protein by using E6AP

(2020) Amjad Ali et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

DNA mismatches reveal conformational penalties in protein–DNA recognition

(2020) Ariel Afek et al.   NATURE

Single molecule studies reveal that p53 tetramers dynamically bind response elements containing one or two half sites

(2020) Elina Ly et al.   Scientific Reports

Tp53 Suppression Promotes Cardiomyocyte Proliferation during Zebrafish Heart Regeneration

(2020) Adam Shoffner et al.   Cell Reports

Intronic TP53 Polymorphisms Are Associated with Increased Δ133TP53 Transcript, Immune Infiltration and Cancer Risk

(2020) Ramona A. Eiholzer et al.   Cancers

The complex architecture of p53 binding sites

(2020) Alon Senitzki et al.   NUCLEIC ACIDS RESEARCH

The non-structural NS1 protein of influenza viruses modulates TP53 splicing through the host factor CPSF4

(2019) Julia Dubois et al.   JOURNAL OF VIROLOGY

Radiation-induced astrocyte senescence is rescued by Δ133p53

(2019) Casmir Turnquist et al.   NEURO-ONCOLOGY

The multiple mechanisms that regulate p53 activity and cell fate

(2019) Antonina Hafner et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Expression of MDM2 in Macrophages Promotes the Early Postentry Steps of HIV-1 Infection through Inhibition of p53

(2019) Yann Breton et al.   JOURNAL OF VIROLOGY

Delay in development and behavioural abnormalities in the absence of p53 in zebrafish

(2019) Seham Elabd et al.   PLoS One

Integrated Analysis of TP53 Gene and Pathway Alterations in The Cancer Genome Atlas

(2019) Lawrence A. Donehower et al.   Cell Reports

Mitochondrial Homeostasis and Cellular Senescence

(2019) Panagiotis V.S. Vasileiou et al.   Cells

Transposable elements in human genetic disease

(2019) Lindsay M. Payer et al.   NATURE REVIEWS GENETICS

The Δ133p53β isoform promotes an immunosuppressive environment leading to aggressive prostate cancer

(2019) Marina Kazantseva et al.   Cell Death & Disease

Functional interplay between p53 and Δ133p53 in adaptive stress response

(2019) Lu Gong et al.   CELL DEATH AND DIFFERENTIATION

Splicing factor DHX15 affects tp53 and mdm2 expression via alternate splicing and promoter usage

(2019) John McElderry et al.   HUMAN MOLECULAR GENETICS

GD2‐directed CAR‐T cells in combination with HGF‐targeted neutralizing antibody (AMG102) prevent primary tumor growth and metastasis in Ewing sarcoma

(2019) Manish Charan et al.   INTERNATIONAL JOURNAL OF CANCER

p53-responsive TLR8 SNP enhances human innate immune response to respiratory syncytial virus

(2019) Daniel Menendez et al.   JOURNAL OF CLINICAL INVESTIGATION

Splicing factor SRSF1 controls T cell hyperactivity and systemic autoimmunity

(2019) Takayuki Katsuyama et al.   JOURNAL OF CLINICAL INVESTIGATION

Rebalancing Immune Homeostasis to Treat Autoimmune Diseases

(2019) David A. Horwitz et al.   TRENDS IN IMMUNOLOGY

Metabolic functions of the tumor suppressor p53: Implications in normal physiology, metabolic disorders, and cancer

(2019) Matthieu Lacroix et al.   Molecular Metabolism

The Emerging Landscape of p53 Isoforms in Physiology, Cancer and Degenerative Diseases

(2019) Thineskrishna Anbarasan et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Characterization of p53 Family Homologs in Evolutionary Remote Branches of Holozoa

(2019) Martin Bartas et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Role of p53/NF-κB functional balance in respiratory syncytial virus-induced inflammation response

(2018) Daniela Machado et al.   JOURNAL OF GENERAL VIROLOGY

Elevation of the TP53 isoform Δ133p53β in glioblastomas: an alternative to mutant p53 in promoting tumour development

(2018) Marina Kazantseva et al.   JOURNAL OF PATHOLOGY

Rubella viruses shift cellular bioenergetics to a more oxidative and glycolytic phenotype with a strain-specific requirement for glutamine

(2018) Nicole C. Bilz et al.   JOURNAL OF VIROLOGY

A mouse model of the Δ133p53 isoform: roles in cancer progression and inflammation

(2018) Marina Kazantseva et al.   MAMMALIAN GENOME

A functional interplay between Δ133p53 and ΔNp63 in promoting glycolytic metabolism to fuel cancer cell proliferation

(2018) Lu Gong et al.   ONCOGENE

p53 isoforms regulate premature aging in human cells

(2018) Natalia von Muhlinen et al.   ONCOGENE

A novel p53 paralogue mediates antioxidant defense of mosquito cells to survive dengue virus replication

(2018) Tien-Huang Chen et al.   VIROLOGY

Inhibition of HIV early replication by the p53 and its downstream gene p21

(2018) Binshan Shi et al.   Virology Journal

Δ133p53α, a natural p53 isoform, contributes to conditional reprogramming and long-term proliferation of primary epithelial cells

(2018) Abdul M. Mondal et al.   Cell Death & Disease

∆133p53 isoform promotes tumour invasion and metastasis via interleukin-6 activation of JAK-STAT and RhoA-ROCK signalling

(2018) Hamish Campbell et al.   Nature Communications

Regulation of the interferon-gamma (IFN-γ) pathway by p63 and Δ133p53 isoform in different breast cancer subtypes

(2018) Sunali Y. Mehta et al.   Oncotarget

HERV Envelope Proteins: Physiological Role and Pathogenic Potential in Cancer and Autoimmunity

(2018) Nicole Grandi et al.   Frontiers in Microbiology

Influenza A Virus Facilitates Its Infectivity by Activating p53 to Inhibit the Expression of Interferon-Induced Transmembrane Proteins

(2018) Bei Wang et al.   Frontiers in Immunology

p53 and the Viral Connection: Back into the Future ‡

(2018) Ronit Aloni-Grinstein et al.   Cancers

Transposons, p53 and Genome Security

(2018) Bhavana Tiwari et al.   TRENDS IN GENETICS

p53 Isoforms and Their Implications in Cancer

(2018) Maximilian Vieler et al.   Cancers

Human endogenous retrovirus-K (HML-2): a comprehensive review

(2018) Marta Garcia-Montojo et al.   CRITICAL REVIEWS IN MICROBIOLOGY

Conformational stability and dynamics of the cancer-associated isoform Δ133p53β are modulated by p53 peptides and p53-specific DNA

(2018) Jiangtao Lei et al.   FASEB JOURNAL

Defining TP53 pioneering capabilities with competitive nucleosome binding assays

(2018) Xinyang Yu et al.   GENOME RESEARCH

Breaking Bad: How Viruses Subvert the Cell Cycle

(2018) Ying Fan et al.   Frontiers in Cellular and Infection Microbiology

Mobile DNA in Health and Disease

(2017) Haig H. Kazazian et al.   NEW ENGLAND JOURNAL OF MEDICINE

Diverse p53/DNA binding modes expand the repertoire of p53 response elements

(2017) Pratik Vyas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

p53 regulates the cardiac transcriptome

(2017) Tak W. Mak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of Δ133p53 isoform in NF-κB inhibitor PDTC-mediated growth inhibition of MKN45 gastric cancer cells

(2017) Hong-Mei Zhang et al.   WORLD JOURNAL OF GASTROENTEROLOGY

SRSF1 promotes vascular smooth muscle cell proliferation through a Δ133p53/EGR1/KLF5 pathway

(2017) Ning Xie et al.   Nature Communications

Synergistic IL-6 and IL-8 paracrine signalling pathway infers a strategy to inhibit tumour cell migration

(2017) Hasini Jayatilaka et al.   Nature Communications

IFN-β induces greater antiproliferative and proapoptotic effects and increased p53 signaling compared with IFN-α in PBMCs of Adult T-cell Leukemia/Lymphoma patients

(2017) T Dierckx et al.   Blood Cancer Journal

InheritedTP53Mutations and the Li–Fraumeni Syndrome

(2017) Tanya Guha et al.   Cold Spring Harbor Perspectives in Medicine

A human endogenous retrovirus-derived gene that can contribute to oncogenesis by activating the ERK pathway and inducing migration and invasion

(2017) Cécile Lemaître et al.   PLoS Pathogens

The Δ133p53 Isoform Reduces Wtp53-induced Stimulation of DNA Pol γ Activity in the Presence and Absence of D4T

(2017) Kai Liu et al.   Aging and Disease

Friends-Enemies: Endogenous Retroviruses Are Major Transcriptional Regulators of Human DNA

(2017) Anton A. Buzdin et al.   Frontiers in Chemistry

Identification of two p53 isoforms from Litopenaeus vannamei and their interaction with NF-κB to induce distinct immune response

(2017) Haoyang Li et al.   Scientific Reports

P53 and the defenses against genome instability caused by transposons and repetitive elements

(2016) Arnold J. Levine et al.   BIOESSAYS

p53 isoforms regulate astrocyte-mediated neuroprotection and neurodegeneration

(2016) C Turnquist et al.   CELL DEATH AND DIFFERENTIATION

Identification of Kaposi Sarcoma Herpesvirus (KSHV) vIRF1 Protein as a Novel Interaction Partner of Human Deubiquitinase USP7

(2016) Sara Chavoshi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Δ40p53α suppresses tumor cell proliferation and induces cellular senescence in hepatocellular carcinoma cells

(2016) Akinobu Ota et al.   JOURNAL OF CELL SCIENCE

The role of the p53 tumor suppressor in metabolism and diabetes

(2016) Che-Pei Kung et al.   JOURNAL OF ENDOCRINOLOGY

Immune suppression of JC virus gene expression is mediated by SRSF1

(2016) Rahsan Sariyer et al.   JOURNAL OF NEUROVIROLOGY

The Δ133p53 isoform and its mouse analogue Δ122p53 promote invasion and metastasis involving pro-inflammatory molecules interleukin-6 and CCL2

(2016) I Roth et al.   ONCOGENE

p53 down-regulates SARS coronavirus replication and is targeted by the SARS-unique domain and PLprovia E3 ubiquitin ligase RCHY1

(2016) Yue Ma-Lauer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ZIKA virus elicits P53 activation and genotoxic stress in human neural progenitors similar to mutations involved in severe forms of genetic microcephaly and p53

(2016) Vincent El Ghouzzi et al.   Cell Death & Disease

p53 Isoforms: Key Regulators of the Cell Fate Decision

(2016) Sebastien M. Joruiz et al.   Cold Spring Harbor Perspectives in Medicine

Roles for retrotransposon insertions in human disease

(2016) Dustin C. Hancks et al.   Mobile DNA

Exploring the Homeostatic and Sensory Roles of the Immune System

(2016) Rafael Elias Marques et al.   Frontiers in Immunology

p53 isoform Δ133p53 promotes efficiency of induced pluripotent stem cells and ensures genomic integrity during reprogramming

(2016) Lu Gong et al.   Scientific Reports

Transcriptional analysis of immune-related gene expression in p53-deficient mice with increased susceptibility to influenza A virus infection

(2015) Wenjun Yan et al.   BMC Medical Genomics

The MDM4/MDM2-p53-IGF1 axis controls axonal regeneration, sprouting and functional recovery after CNS injury

(2015) Yashashree Joshi et al.   BRAIN

p53 isoform Δ113p53/Δ133p53 promotes DNA double-strand break repair to protect cell from death and senescence in response to DNA damage

(2015) Lu Gong et al.   CELL RESEARCH

p53 genes function to restrain mobile elements

(2015) Annika Wylie et al.   GENES & DEVELOPMENT

SRSF1 Facilitates Cytosolic DNA-Induced Production of Type I Interferons Recognized by RIG-I

(2015) Feng Xue et al.   PLoS One

Nlrp6 regulates intestinal antiviral innate immunity

(2015) Penghua Wang et al.   SCIENCE

p53 coordinates with Δ133p53 isoform to promote cell survival under low-level oxidative stress

(2015) Lu Gong et al.   Journal of Molecular Cell Biology

Δ122p53, a mouse model of Δ133p53α, enhances the tumor-suppressor activities of an attenuated p53 mutant

(2015) T L Slatter et al.   Cell Death & Disease

Genome-wide profiling of p53-regulated enhancer RNAs uncovers a subset of enhancers controlled by a lncRNA

(2015) Nicolas Léveillé et al.   Nature Communications

The p53 Isoform Δ133p53β Promotes Cancer Stem Cell Potential

(2015) Nikola Arsic et al.   Stem Cell Reports

Antiviral Potential of ERK/MAPK and PI3K/AKT/mTOR Signaling Modulation for Middle East Respiratory Syndrome Coronavirus Infection as Identified by Temporal Kinome Analysis

(2014) Jason Kindrachuk et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Drosophila p53 controls Notch expression and balances apoptosis and proliferation

(2014) Rocío Simón et al.   APOPTOSIS

p53 and NF-κB Coregulate Proinflammatory Gene Responses in Human Macrophages

(2014) Julie M. Lowe et al.   CANCER RESEARCH

Caught in the cross fire: p53 in inflammation

(2014) Tomer Cooks et al.   CARCINOGENESIS

Modulation of p53β and p53γ expression by regulating the alternative splicing of TP53 gene modifies cellular response

(2014) V Marcel et al.   CELL DEATH AND DIFFERENTIATION

Interplay of cell proliferation and cell death inDrosophilatissue regeneration

(2014) Soshiro Kashio et al.   DEVELOPMENT GROWTH & DIFFERENTIATION

TP53 engagement with the genome occurs in distinct local chromatin environments via pioneer factor activity

(2014) Morgan A. Sammons et al.   GENOME RESEARCH

Downmodulation of Tumor Suppressor p53 by T Cell Receptor Signaling Is Critical for Antigen-Specific CD4+ T Cell Responses

(2014) Masashi Watanabe et al.   IMMUNITY

Non-Cell Autonomous or Secretory Tumor Suppression

(2014) Christelle En Lin Chua et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Activity of Hexokinase Is Increased by Its Interaction with Hepatitis C Virus Protein NS5A

(2014) C. Ramiere et al.   JOURNAL OF VIROLOGY

Inappropriate p53 activation during development induces features of CHARGE syndrome

(2014) Jeanine L. Van Nostrand et al.   NATURE

p53  is a transcriptionally inactive p53 isoform able to reprogram cells toward a metastatic-like state

(2014) S. Senturk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chlamydia infection depends on a functional MDM2-p53 axis

(2014) Erik González et al.   Nature Communications

Regulation of p53 and Rb Links the Alternative NF-κB Pathway to EZH2 Expression and Cell Senescence

(2014) Alessio Iannetti et al.   PLoS Genetics

Global analysis of p53-regulated transcription identifies its direct targets and unexpected regulatory mechanisms

(2014) Mary Ann Allen et al.   eLife

Oxidative stress activates a specific p53 transcriptional response that regulates cellular senescence and aging

(2013) Valentina Gambino et al.   AGING CELL

Effects of Δ40p53, an isoform of p53 lacking the N-terminus, on transactivation capacity of the tumor suppressor protein p53

(2013) Hind Hafsi et al.   BMC CANCER

IFNβ-dependent increases in STAT1, STAT2, and IRF9 mediate resistance to viruses and DNA damage

(2013) HyeonJoo Cheon et al.   EMBO JOURNAL

The C terminus of p53 regulates gene expression by multiple mechanisms in a target- and tissue-specific manner in vivo

(2013) P.-J. Hamard et al.   GENES & DEVELOPMENT

p53 isoforms regulate aging- and tumor-associated replicative senescence in T lymphocytes

(2013) Abdul M. Mondal et al.   JOURNAL OF CLINICAL INVESTIGATION

Tumor Suppressor p53 Inhibits Systemic Autoimmune Diseases by Inducing Regulatory T Cells

(2013) H. Kawashima et al.   JOURNAL OF IMMUNOLOGY

Dominant Effects of Δ40p53 on p53 Function and Melanoma Cell Fate

(2013) Rie Takahashi et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Roles of p53 in Herpes Simplex Virus 1 Replication

(2013) Y. Maruzuru et al.   JOURNAL OF VIROLOGY

The Human Adenovirus 5 L4 Promoter Is Activated by Cellular Stress Response Protein p53

(2013) J. Wright et al.   JOURNAL OF VIROLOGY

Rotavirus-Encoded Nonstructural Protein 1 Modulates Cellular Apoptotic Machinery by Targeting Tumor Suppressor Protein p53

(2013) R. Bhowmick et al.   JOURNAL OF VIROLOGY

p53 Tumor Suppressor Protein Stability and Transcriptional Activity Are Targeted by Kaposi's Sarcoma-Associated Herpesvirus-Encoded Viral Interferon Regulatory Factor 3

(2013) P. Baresova et al.   MOLECULAR AND CELLULAR BIOLOGY

Transcriptional cooperation between p53 and NF-κB p65 regulates microRNA-224 transcription in mouse ovarian granulosa cells

(2013) Meng Liang et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Hepatitis C Virus NS2 Protein Inhibits DNA Damage Pathway by Sequestering p53 to the Cytoplasm

(2013) Cintia Bittar et al.   PLoS One

Regulation of p53 is critical for vertebrate limb regeneration

(2013) M. H. Yun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Safeguards for Cell Cooperation in Mouse Embryogenesis Shown by Genome-Wide Cheater Screen

(2013) M. Dejosez et al.   SCIENCE

p53 increases MHC class I expression by upregulating the endoplasmic reticulum aminopeptidase ERAP1

(2013) Bei Wang et al.   Nature Communications

The HumanTLRInnate Immune Gene Family Is Differentially Influenced by DNA Stress andp53Status in Cancer Cells

(2012) Maria Shatz et al.   CANCER RESEARCH

Does Δ133p53 isoform trigger inflammation and autoimmunity?

(2012) Hamish Campbell et al.   CELL CYCLE

Drosophila p53 isoforms differentially regulate apoptosis and apoptosis-induced proliferation

(2012) M-L Dichtel-Danjoy et al.   CELL DEATH AND DIFFERENTIATION

Calpain Activation by the Shigella flexneri Effector VirA Regulates Key Steps in the Formation and Life of the Bacterium's Epithelial Niche

(2012) Jean Bergounioux et al.   Cell Host & Microbe

Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling

(2012) Paul D. Ray et al.   CELLULAR SIGNALLING

Reactive Oxygen Species in Health and Disease

(2012) Assim A. Alfadda et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Neisseria gonorrhoeae infection causes DNA damage and affects the expression of p21, p27 and p53 in non-tumor epithelial cells

(2012) Katarina Vielfort et al.   JOURNAL OF CELL SCIENCE

Influenza A Viruses Control Expression of Proviral Human p53 Isoforms p53β and Δ133p53α

(2012) Olivier Terrier et al.   JOURNAL OF VIROLOGY

eRNAs Are Required for p53-Dependent Enhancer Activity and Gene Transcription

(2012) Carlos A. Melo et al.   MOLECULAR CELL

p53 isoform profiling in glioblastoma and injured brain

(2012) R Takahashi et al.   ONCOGENE

The p53 isoform, Δ133p53α, stimulates angiogenesis and tumour progression

(2012) H Bernard et al.   ONCOGENE

Downregulation of splicing factor SRSF3 induces p53β, an alternatively spliced isoform of p53 that promotes cellular senescence

(2012) Y Tang et al.   ONCOGENE

Respiratory Syncytial Virus Matrix Protein Induces Lung Epithelial Cell Cycle Arrest through a p53 Dependent Pathway

(2012) Tao Bian et al.   PLoS One

Pathogenic bacterium Helicobacter pylori alters the expression profile of p53 protein isoforms and p53 response to cellular stresses

(2012) J. Wei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Impact of Alu repeats on the evolution of human p53 binding sites

(2011) Feng Cui et al.   Biology Direct

Hyperproliferation, cancer, and inflammation in mice expressing a  133p53-like isoform

(2011) T. L. Slatter et al.   BLOOD

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Diverse p63 and p73 isoforms regulate Δ133p53 expression through modulation of the internal TP53 promoter activity

(2011) V Marcel et al.   CELL DEATH AND DIFFERENTIATION

 40 Isoform of p53 Controls  -Cell Proliferation and Glucose Homeostasis in Mice

(2011) C. Hinault et al.   DIABETES

PD-L1 co-stimulation contributes to ligand-induced T cell receptor down-modulation on CD8+T cells

(2011) Katarzyna Karwacz et al.   EMBO Molecular Medicine

Trp53 negatively regulates autoimmunity via the STAT3-Th17 axis

(2011) Shuzhong Zhang et al.   FASEB JOURNAL

Proteasomal Degradation of p53 by Human Papillomavirus E6 Oncoprotein Relies on the Structural Integrity of p53 Core Domain

(2011) Xavier Bernard et al.   PLoS One

Altered longevity-assurance activity of p53:p44 in the mouse causes memory loss, neurodegeneration and premature death

(2010) Mariana Pehar et al.   AGING CELL

Salmonella typhimurium infection increases p53 acetylation in intestinal epithelial cells

(2010) Shaoping Wu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Differential regulation of p53 function by the N-terminal ΔNp53 and Δ113p53 isoforms in zebrafish embryos

(2010) William R Davidson et al.   BMC DEVELOPMENTAL BIOLOGY

p53 directly transactivates Δ133p53α, regulating cell fate outcome in response to DNA damage

(2010) M Aoubala et al.   CELL DEATH AND DIFFERENTIATION

Δ160p53 is a novel N-terminal p53 isoform encoded by Δ133p53 transcript

(2010) Virginie Marcel et al.   FEBS LETTERS

Regulation of p53 Tumor Suppressor by Helicobacter pylori in Gastric Epithelial Cells

(2010) Jinxiong Wei et al.   GASTROENTEROLOGY

 40p53 controls the switch from pluripotency to differentiation by regulating IGF signaling in ESCs

(2010) E. Ungewitter et al.   GENES & DEVELOPMENT

ΔN133p53 expression levels in relation to haplotypes of the TP53 internal promoter region

(2010) Ilaria Bellini et al.   HUMAN MUTATION

Distinct p53, p53:LANA, and LANA Complexes in Kaposi's Sarcoma-Associated Herpesvirus Lymphomas

(2010) W. Chen et al.   JOURNAL OF VIROLOGY

Human Cytomegalovirus Activates Glucose Transporter 4 Expression To Increase Glucose Uptake during Infection

(2010) Y. Yu et al.   JOURNAL OF VIROLOGY

Endoplasmic Reticulum Stress Induces G2 Cell-Cycle Arrest via mRNA Translation of the p53 Isoform p53/47

(2010) Karima Bourougaa et al.   MOLECULAR CELL

Zebrafish heart regeneration occurs by cardiomyocyte dedifferentiation and proliferation

(2010) Chris Jopling et al.   NATURE

Sequence-dependent cooperative binding of p53 to DNA targets and its relationship to the structural properties of the DNA targets

(2010) Itai Beno et al.   NUCLEIC ACIDS RESEARCH

p53 regulates the transcription of its Δ133p53 isoform through specific response elements contained within the TP53 P2 internal promoter

(2010) V Marcel et al.   ONCOGENE

The RNA helicase p68 modulates expression and function of the Δ133 isoform(s) of p53 and is inversely associated with Δ133p53 expression in breast cancer

(2010) H C Moore et al.   ONCOGENE

Cross talk between stimulated NF-κB and the tumor suppressor p53

(2010) G Schneider et al.   ONCOGENE

Hepatocyte Growth Factor Modulates Interleukin-6 Production in Bone Marrow Derived Macrophages: Implications for Inflammatory Mediated Diseases

(2010) Gina M. Coudriet et al.   PLoS One

Dual Role of p53 in Innate Antiviral Immunity

(2010) Carmen Rivas et al.   Viruses-Basel

A planarian p53 homolog regulates proliferation and self-renewal in adult stem cell lineages

(2009) Bret J. Pearson et al.   DEVELOPMENT

c-Met signaling promotes IL-6-induced myeloma cell proliferation

(2009) Håkon Hov et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

p53 isoform  113p53 is a p53 target gene that antagonizes p53 apoptotic activity via BclxL activation in zebrafish

(2009) J. Chen et al.   GENES & DEVELOPMENT

Kaposi's Sarcoma-Associated Herpesvirus Viral Interferon Regulatory Factor 4 Targets MDM2 To Deregulate the p53 Tumor Suppressor Pathway

(2009) H.-R. Lee et al.   JOURNAL OF VIROLOGY

Human Cytomegalovirus IE1-72 Protein Interacts with p53 and Inhibits p53-Dependent Transactivation by a Mechanism Different from That of IE2-86 Protein

(2009) E.-S. Hwang et al.   JOURNAL OF VIROLOGY

p53 isoforms Δ133p53 and p53β are endogenous regulators of replicative cellular senescence

(2009) Kaori Fujita et al.   NATURE CELL BIOLOGY

Posttranslational Modification of p53: Cooperative Integrators of Function

(2009) D. W. Meek et al.   Cold Spring Harbor Perspectives in Biology

Small Molecular Weight Variants of p53 Are Expressed in Human Melanoma Cells and Are Induced by the DNA-Damaging Agent Cisplatin

(2008) K. A. Avery-Kiejda et al.   CLINICAL CANCER RESEARCH

ROS and p53: A versatile partnership

(2008) Bin Liu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Interferon-γ induces cellular senescence through p53-dependent DNA damage signaling in human endothelial cells

(2008) Kwang Seok Kim et al.   MECHANISMS OF AGEING AND DEVELOPMENT

The genome of the choanoflagellate Monosiga brevicollis and the origin of metazoans

(2008) Nicole King et al.   NATURE

Regenerative capacity of neural precursors in the adult mammalian brain is under the control of p53

(2007) Silvia Medrano et al.   NEUROBIOLOGY OF AGING