标题
Role of p53 in the Regulation of Cellular Senescence
作者
关键词
-
出版物
Biomolecules
Volume 10, Issue 3, Pages 420
出版商
MDPI AG
发表日期
2020-03-09
DOI
10.3390/biom10030420
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- ITGB4 deficiency induces senescence of airway epithelial cells through p53 activation
- (2019) Lin Yuan et al. FEBS Journal
- Radiation-induced astrocyte senescence is rescued by Δ133p53
- (2019) Casmir Turnquist et al. NEURO-ONCOLOGY
- Senescent Cells in Early Vascular Ageing and Bone Disease of Chronic Kidney Disease—A Novel Target for Treatment
- (2019) Sam Hobson et al. Toxins
- Mitochondrial Dysfunction in Huntington’s Disease; Interplay Between HSF1, p53 and PGC-1α Transcription Factors
- (2019) Taylor A. Intihar et al. Frontiers in Cellular Neuroscience
- Short-term gain, long-term pain: the senescence life cycle and cancer
- (2019) Adelyne Sue Li Chan et al. GENES & DEVELOPMENT
- Upregulation of the p53-p21 pathway by G2019S LRRK2 contributes to the cellular senescence and accumulation of α-synuclein
- (2019) Dong Hwan Ho et al. CELL CYCLE
- Negative regulation of p53-induced senescence by N-WASP is crucial for DMBA/TPA-induced skin tumor formation
- (2019) Hui Li et al. CANCER RESEARCH
- Hsp90β interacts with MDM2 to suppress p53‐dependent senescence during skeletal muscle regeneration
- (2019) Min Yi He et al. AGING CELL
- Inflammatory signaling in genomically instable cancers
- (2019) Francien Talens et al. CELL CYCLE
- The Kindlin2-p53-SerpinB2 signaling axis is required for cellular senescence in breast cancer
- (2019) Khalid Sossey-Alaoui et al. Cell Death & Disease
- Reduced subcutaneous adipogenesis in human hypertrophic obesity is linked to senescent precursor cells
- (2019) Birgit Gustafson et al. Nature Communications
- Mitochondrial Homeostasis and Cellular Senescence
- (2019) Panagiotis V.S. Vasileiou et al. Cells
- Hallmarks of senescence and aging
- (2019) Slavica Dodig et al. Biochemia Medica
- Autophagy role(s) in response to oncogenes and DNA replication stress
- (2019) Riccardo Vanzo et al. CELL DEATH AND DIFFERENTIATION
- Cellular senescence: at the nexus between ageing and diabetes
- (2019) Allyson K. Palmer et al. DIABETOLOGIA
- Conjugated Physiological Resveratrol Metabolites Induce Senescence in Breast Cancer Cells: Role of p53/p21 and p16/Rb Pathways, and ABC Transporters
- (2019) Juan Antonio Giménez‐Bastida et al. MOLECULAR NUTRITION & FOOD RESEARCH
- The Multifaceted p21 (Cip1/Waf1/CDKN1A) in Cell Differentiation, Migration and Cancer Therapy
- (2019) Kreis et al. Cancers
- The Role of the Cyclin Dependent Kinase Inhibitor p21cip1/waf1 in Targeting Cancer: Molecular Mechanisms and Novel Therapeutics
- (2019) Al Bitar et al. Cancers
- The TGF-β1/p53/PAI-1 Signaling Axis in Vascular Senescence: Role of Caveolin-1
- (2019) Rohan Samarakoon et al. Biomolecules
- Cellular Senescence: Defining a Path Forward
- (2019) Vassilis Gorgoulis et al. CELL
- p53 Isoforms in Cellular Senescence- and Ageing-Associated Biological and Physiological Functions
- (2019) Kaori Fujita INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- A dynamical systems model for the measurement of cellular senescence
- (2019) Daniel Galvis et al. Journal of the Royal Society Interface
- The Signaling of Cellular Senescence in Diabetic Nephropathy
- (2019) Yabing Xiong et al. Oxidative Medicine and Cellular Longevity
- Dissecting Aging and Senescence—Current Concepts and Open Lessons
- (2019) Schmeer et al. Cells
- Regulation of senescence and the SASP by the transcription factor C/EBPβ
- (2019) Jacqueline Salotti et al. EXPERIMENTAL GERONTOLOGY
- Genetic Ablation of p16(Ink4a) Does Not Protect Against Cellular Senescence in Mouse Models of COPD/Emphysema
- (2018) Isaac K Sundar et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Paracrine roles of cellular senescence in promoting tumourigenesis
- (2018) Jose Mario Gonzalez-Meljem et al. BRITISH JOURNAL OF CANCER
- Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
- (2018) Lorenzo Galluzzi et al. CELL DEATH AND DIFFERENTIATION
- Cellular senescence in brain aging and neurodegenerative diseases: evidence and perspectives
- (2018) Darren J. Baker et al. JOURNAL OF CLINICAL INVESTIGATION
- Mechanisms and functions of cellular senescence
- (2018) Nicolás Herranz et al. JOURNAL OF CLINICAL INVESTIGATION
- p53 in Bronchial Club Cells Facilitates Chronic Lung Inflammation by Promoting Senescence
- (2018) Adi Sagiv et al. Cell Reports
- Role of p53 in the Regulation of the Inflammatory Tumor Microenvironment and Tumor Suppression
- (2018) Ikuno Uehara et al. Cancers
- Cellular Senescence in Chronic Obstructive Pulmonary Disease: Multifaceted and Multifunctional
- (2018) Veena B. Antony et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Obesity and type-2 diabetes as inducers of premature cellular senescence and ageing
- (2018) Dominick G. A. Burton et al. BIOGERONTOLOGY
- Endothelial Extracellular Vesicles Produced by Senescent Cells: Pathophysiological Role in the Cardiovascular Disease Associated with all Types of Diabetes Mellitus
- (2018) Julia Carracedo et al. Current Vascular Pharmacology
- p53 Functions in Adipose Tissue Metabolism and Homeostasis
- (2018) Jelena Krstic et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Ageing, Cellular Senescence and Neurodegenerative Disease
- (2018) Marios Kritsilis et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Clearance of senescent glial cells prevents tau-dependent pathology and cognitive decline
- (2018) Tyler J. Bussian et al. NATURE
- Chromosomal instability-induced senescence potentiates cell non-autonomous tumourigenic effects
- (2018) Qianqian He et al. Oncogenesis
- The dynamic nature of senescence in cancer
- (2018) Soyoung Lee et al. NATURE CELL BIOLOGY
- mTOR kinase leads to PTEN-loss-induced cellular senescence by phosphorylating p53
- (2018) Seung Hee Jung et al. ONCOGENE
- Cellular senescence regulated by SWI/SNF complex subunits through p53/p21 and p16/pRB pathway
- (2017) Ling He et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- LncRNA-mediated SIRT1/FoxO3a and SIRT1/p53 signaling pathways regulate type II alveolar epithelial cell senescence in patients with chronic obstructive pulmonary disease
- (2017) Chao Gu et al. Molecular Medicine Reports
- When the guardian sleeps: Reactivation of the p53 pathway in cancer
- (2017) Olaf Merkel et al. MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH
- Cellular senescence in gastrointestinal diseases: from pathogenesis to therapeutics
- (2017) Nina Frey et al. Nature Reviews Gastroenterology & Hepatology
- Census and evaluation of p53 target genes
- (2017) M Fischer ONCOGENE
- Pathomechanisms of Oxidative Stress in Inflammatory Bowel Disease and Potential Antioxidant Therapies
- (2017) Tian Tian et al. Oxidative Medicine and Cellular Longevity
- Exosomes maintain cellular homeostasis by excreting harmful DNA from cells
- (2017) Akiko Takahashi et al. Nature Communications
- Effects of bioactive compounds on senescence and components of senescence associated secretory phenotypes in vitro
- (2017) Janubová Mária et al. Food & Function
- Inflammatory responses and inflammation-associated diseases in organs
- (2017) Linlin Chen et al. Oncotarget
- Induction of senescence in primary glioblastoma cells by serum and TGFβ
- (2017) Ritesh Kumar et al. Scientific Reports
- Misidentified Human Gene Functions with Mouse Models: The Case of the Retinoblastoma Gene Family in Senescence
- (2017) Nicola Alessio et al. NEOPLASIA
- Redox control of senescence and age-related disease
- (2017) Akshaya Chandrasekaran et al. Redox Biology
- Telomeres and Cell Senescence - Size Matters Not
- (2017) Stella Victorelli et al. EBioMedicine
- The Dual Role of Cellular Senescence in Developing Tumors and Their Response to Cancer Therapy
- (2017) Markus Schosserer et al. Frontiers in Oncology
- Markers of cellular senescence. Telomere shortening as a marker of cellular senescence
- (2016) Alexandra Bernadotte et al. Aging-US
- Senescence and cancer: An evolving inflammatory paradox
- (2016) Megan K. Ruhland et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- To clear, or not to clear (senescent cells)? That is the question
- (2016) Amaia Lujambio BIOESSAYS
- p53 isoforms regulate astrocyte-mediated neuroprotection and neurodegeneration
- (2016) C Turnquist et al. CELL DEATH AND DIFFERENTIATION
- Cell cycle proliferation decisions: the impact of single cell analyses
- (2016) Jacob P. Matson et al. FEBS Journal
- Dopaminergic neuron-specific deletion of p53 gene is neuroprotective in an experimental Parkinson's disease model
- (2016) Xin Qi et al. JOURNAL OF NEUROCHEMISTRY
- The persistent dynamic secrets of senescence
- (2016) Clemens A. Schmitt NATURE CELL BIOLOGY
- Ionizing Radiation-Induced Endothelial Cell Senescence and Cardiovascular Diseases
- (2016) Yingying Wang et al. RADIATION RESEARCH
- The role of p53 in cancer drug resistance and targeted chemotherapy
- (2016) Karin Hientz et al. Oncotarget
- p53 and the Carcinogenicity of Chronic Inflammation
- (2016) Andrei V. Gudkov et al. Cold Spring Harbor Perspectives in Medicine
- p53 in the DNA-Damage-Repair Process
- (2016) Ashley B. Williams et al. Cold Spring Harbor Perspectives in Medicine
- Unfolded p53 in the pathogenesis of Alzheimer's disease: is HIPK2 the link?
- (2016) Serena Stanga et al. Aging-US
- Cellular Senescence in Type 2 Diabetes: A Therapeutic Opportunity
- (2015) Allyson K. Palmer et al. DIABETES
- Cellular senescence and the aging brain
- (2015) Shankar J. Chinta et al. EXPERIMENTAL GERONTOLOGY
- Cellular senescence in aging and age-related disease: from mechanisms to therapy
- (2015) Bennett G Childs et al. NATURE MEDICINE
- Integrated Stochastic Model of DNA Damage Repair by Non-homologous End Joining and p53/p21- Mediated Early Senescence Signalling
- (2015) David W. P. Dolan et al. PLoS Computational Biology
- DDR-mediated crosstalk between DNA-damaged cells and their microenvironment
- (2015) Nicolas Malaquin et al. Frontiers in Genetics
- Are there roles for brain cell senescence in aging and neurodegenerative disorders?
- (2014) Florence C. C. Tan et al. BIOGERONTOLOGY
- Senescence and apoptosis: dueling or complementary cell fates?
- (2014) B. G. Childs et al. EMBO REPORTS
- The effects of fucodian on senescence are controlled by the p16INK4a-pRb and p14Arf-p53 pathways in hepatocellular carcinoma and hepatic cell lines
- (2014) EUN-YOUNG MIN et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- The role of senescent cells in ageing
- (2014) Jan M. van Deursen NATURE
- Emerging roles of the p38 MAPK and PI3K/AKT/mTOR pathways in oncogene-induced senescence
- (2014) Yingxi Xu et al. TRENDS IN BIOCHEMICAL SCIENCES
- Glucocorticoids induce senescence in primary human tenocytes by inhibition of sirtuin 1 and activation of the p53/p21 pathway: in vivo and in vitro evidence
- (2013) Raewyn C Poulsen et al. ANNALS OF THE RHEUMATIC DISEASES
- Senescence at a glance
- (2013) J. S. Pawlikowski et al. JOURNAL OF CELL SCIENCE
- p53-dependent gene repression through p21 is mediated by recruitment of E2F4 repression complexes
- (2013) E K Benson et al. ONCOGENE
- Senescence and aging: the critical roles of p53
- (2013) A Rufini et al. ONCOGENE
- Fenofibrate triggers apoptosis of glioblastoma cells in vitro
- (2012) Antonio Giordano et al. CELL CYCLE
- Emerging roles of RB family: New defense mechanisms against tumor progression
- (2012) Paola Indovina et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Various modes of cell death induced by DNA damage
- (2012) O Surova et al. ONCOGENE
- A p53-independent role for the MDM2 antagonist Nutlin-3 in DNA damage response initiation
- (2011) Jane M Valentine et al. BMC CANCER
- Effects of p21 deletion in mouse models of premature aging
- (2011) Erica K. Benson et al. CELL CYCLE
- Cellular senescence and tumor suppressor gene p16
- (2011) Hani Rayess et al. INTERNATIONAL JOURNAL OF CANCER
- The oncogenic phosphatase PPM1D confers cisplatin resistance in ovarian carcinoma cells by attenuating checkpoint kinase 1 and p53 activation
- (2011) A Y Ali et al. ONCOGENE
- The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression
- (2010) Jean-Philippe Coppé et al. Annual Review of Pathology-Mechanisms of Disease
- Ras-Induced Senescence and its Physiological Relevance in Cancer
- (2010) T. DiMauro et al. CURRENT CANCER DRUG TARGETS
- The essence of senescence
- (2010) T. Kuilman et al. GENES & DEVELOPMENT
- DNMT3a plays a role in switches between doxorubicin-induced senescence and apoptosis of colorectal cancer cells
- (2010) Yu Zhang et al. INTERNATIONAL JOURNAL OF CANCER
- Pathologies Associated with the p53 Response
- (2010) A. V. Gudkov et al. Cold Spring Harbor Perspectives in Biology
- Doxorubicin induces senescence or apoptosis in rat neonatal cardiomyocytes by regulating the expression levels of the telomere binding factors 1 and 2
- (2009) Paolo Spallarossa et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Blinded by the Light: The Growing Complexity of p53
- (2009) Karen H. Vousden et al. CELL
- Rb2/p130 is the dominating pocket protein in the p53–p21 DNA damage response pathway leading to senescence
- (2009) H Helmbold et al. ONCOGENE
- Oncogene-Induced Senescence Relayed by an Interleukin-Dependent Inflammatory Network
- (2008) Thomas Kuilman et al. CELL
- Senescence, Apoptosis or Autophagy?
- (2008) José Miguel Vicencio et al. GERONTOLOGY
- In Vitro Senescence of Rat Mesenchymal Stem Cells is Accompanied by Downregulation of Stemness-Related and DNA Damage Repair Genes
- (2008) Umberto Galderisi et al. STEM CELLS AND DEVELOPMENT
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started