Global analysis of p53-regulated transcription identifies its direct targets and unexpected regulatory mechanisms

Mapping the p53 transcriptome universe using p53 natural polymorphs

(2013) B Wang et al.   CELL DEATH AND DIFFERENTIATION

RNA-mediated gene activation

(2013) Alan L Jiao et al.   Epigenetics

A high-resolution map of the three-dimensional chromatin interactome in human cells

(2013) Fulai Jin et al.   NATURE

Diverse stresses dramatically alter genome-wide p53 binding and transactivation landscape in human cancer cells

(2013) Daniel Menendez et al.   NUCLEIC ACIDS RESEARCH

p53-dependent gene repression through p21 is mediated by recruitment of E2F4 repression complexes

(2013) E K Benson et al.   ONCOGENE

A Genetic Screen Identifies TCF3/E2A and TRIAP1 as Pathway-Specific Regulators of the Cellular Response to p53 Activation

(2013) Zdenek Andrysik et al.   Cell Reports

Characterization of the p53 Cistrome – DNA Binding Cooperativity Dissects p53's Tumor Suppressor Functions

(2013) Katharina Schlereth et al.   PLoS Genetics

Insights into p53 transcriptional function via genome-wide chromatin occupancy and gene expression analysis

(2012) F Nikulenkov et al.   CELL DEATH AND DIFFERENTIATION

A DR4:tBID axis drives the p53 apoptotic response by promoting oligomerization of poised BAX

(2012) Ryan E Henry et al.   EMBO JOURNAL

Distinct Regulatory Mechanisms and Functions for p53-Activated and p53-Repressed DNA Damage Response Genes in Embryonic Stem Cells

(2012) Mangmang Li et al.   MOLECULAR CELL

eRNAs Are Required for p53-Dependent Enhancer Activity and Gene Transcription

(2012) Carlos A. Melo et al.   MOLECULAR CELL

Systematic identification of genomic markers of drug sensitivity in cancer cells

(2012) Mathew J. Garnett et al.   NATURE

ATM and MET kinases are synthetic lethal with nongenotoxic activation of p53

(2012) Kelly D Sullivan et al.   Nature Chemical Biology

A Rapid, Extensive, and Transient Transcriptional Response to Estrogen Signaling in Breast Cancer Cells

(2011) Nasun Hah et al.   CELL

Role of p53 Serine 46 in p53 Target Gene Regulation

(2011) Leonie Smeenk et al.   PLoS One

Capture of MicroRNA–Bound mRNAs Identifies the Tumor Suppressor miR-34a as a Regulator of Growth Factor Signaling

(2011) Ashish Lal et al.   PLoS Genetics

The C terminus of p53 binds the N-terminal domain of MDM2

(2010) Masha V Poyurovsky et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Differential expression analysis for sequence count data

(2010) Simon Anders et al.   GENOME BIOLOGY

Control of Inducible Gene Expression by Signal-Dependent Transcriptional Elongation

(2009) Diana C. Hargreaves et al.   CELL

Blinded by the Light: The Growing Complexity of p53

(2009) Karen H. Vousden et al.   CELL

Regulation of the p53 transcriptional response by structurally diverse core promoters

(2009) J. M. Morachis et al.   GENES & DEVELOPMENT

Transcriptional control of human p53-regulated genes

(2008) Todd Riley et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Characterization of genome-wide p53-binding sites upon stress response

(2008) Leonie Smeenk et al.   NUCLEIC ACIDS RESEARCH

Nascent RNA Sequencing Reveals Widespread Pausing and Divergent Initiation at Human Promoters

(2008) Leighton J. Core et al.   SCIENCE