标题
Enhancer RNAs are an important regulatory layer of the epigenome
作者
关键词
-
出版物
NATURE STRUCTURAL & MOLECULAR BIOLOGY
Volume 27, Issue 6, Pages 521-528
出版商
Springer Science and Business Media LLC
发表日期
2020-06-09
DOI
10.1038/s41594-020-0446-0
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Antisense-Mediated Transcript Knockdown Triggers Premature Transcription Termination
- (2020) Jong-Sun Lee et al. MOLECULAR CELL
- Directed RNase H Cleavage of Nascent Transcripts Causes Transcription Termination
- (2020) Fan Lai et al. MOLECULAR CELL
- Phase separation of ligand-activated enhancers licenses cooperative chromosomal enhancer assembly
- (2019) Sreejith J. Nair et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- The enhancer RNA ARIEL activates the oncogenic transcriptional program in T-cell acute lymphoblastic leukemia
- (2019) Shi Hao Tan et al. BLOOD
- Long-range enhancer–promoter contacts in gene expression control
- (2019) Stefan Schoenfelder et al. NATURE REVIEWS GENETICS
- High-throughput identification of human SNPs affecting regulatory element activity
- (2019) Joris van Arensbergen et al. NATURE GENETICS
- Determinants of enhancer and promoter activities of regulatory elements
- (2019) Robin Andersson et al. NATURE REVIEWS GENETICS
- Transcription start site profiling uncovers divergent transcription and enhancer-associated RNAs in Drosophila melanogaster
- (2018) Michael P. Meers et al. BMC GENOMICS
- Functional Classification and Experimental Dissection of Long Noncoding RNAs
- (2018) Florian Kopp et al. CELL
- Assessing sufficiency and necessity of enhancer activities for gene expression and the mechanisms of transcription activation
- (2018) Rui R. Catarino et al. GENES & DEVELOPMENT
- Widespread transcriptional pausing and elongation control at enhancers
- (2018) Telmo Henriques et al. GENES & DEVELOPMENT
- The degree of enhancer or promoter activity is reflected by the levels and directionality of eRNA transcription
- (2018) Olga Mikhaylichenko et al. GENES & DEVELOPMENT
- Tyrosine-1 of RNA Polymerase II CTD Controls Global Termination of Gene Transcription in Mammals
- (2018) Nilay Shah et al. MOLECULAR CELL
- A Muscle-Specific Enhancer RNA Mediates Cohesin Recruitment and Regulates Transcription In trans
- (2018) Pei-Fang Tsai et al. MOLECULAR CELL
- The RNA face of phase separation
- (2018) Magdalini Polymenidou SCIENCE
- Coactivator condensation at super-enhancers links phase separation and gene control
- (2018) Benjamin R. Sabari et al. SCIENCE
- Protein Phase Separation: A New Phase in Cell Biology
- (2018) Steven Boeynaems et al. TRENDS IN CELL BIOLOGY
- Fetal γ-globin genes are regulated by the BGLT3 long non-coding RNA locus
- (2018) Maria Soledad Ivaldi et al. BLOOD
- RNAs interact with BRD4 to promote enhanced chromatin engagement and transcription activation
- (2018) Homa Rahnamoun et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Transcription Factors Activate Genes through the Phase-Separation Capacity of Their Activation Domains
- (2018) Ann Boija et al. CELL
- Deregulated Expression of Mammalian lncRNA through Loss of SPT6 Induces R-Loop Formation, Replication Stress, and Cellular Senescence
- (2018) Takayuki Nojima et al. MOLECULAR CELL
- Production of Spliced Long Noncoding RNAs Specifies Regions with Increased Enhancer Activity
- (2018) Noa Gil et al. Cell Systems
- Enhancer transcription reveals subtype-specific gene expression programs controlling breast cancer pathogenesis
- (2017) Hector L. Franco et al. GENOME RESEARCH
- The Elongation Factor Spt6 Maintains ESC Pluripotency by Controlling Super-Enhancers and Counteracting Polycomb Proteins
- (2017) A. Hongjun Wang et al. MOLECULAR CELL
- Intragenic Enhancers Attenuate Host Gene Expression
- (2017) Senthilkumar Cinghu et al. MOLECULAR CELL
- Biomolecular condensates: organizers of cellular biochemistry
- (2017) Salman F. Banani et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- On the Origin of lncRNAs: Missing Link Found
- (2017) Joaquín M. Espinosa TRENDS IN GENETICS
- Mutant p53 shapes the enhancer landscape of cancer cells in response to chronic immune signaling
- (2017) Homa Rahnamoun et al. Nature Communications
- The Super-Enhancer-Derived alncRNA-EC7/Bloodlinc Potentiates Red Blood Cell Development in trans
- (2017) Juan R. Alvarez-Dominguez et al. Cell Reports
- Gene activation by metazoan enhancers: Diverse mechanisms stimulate distinct steps of transcription
- (2016) Robert A. Beagrie et al. BIOESSAYS
- Ever-Changing Landscapes: Transcriptional Enhancers in Development and Evolution
- (2016) Hannah K. Long et al. CELL
- Unlinking an lncRNA from Its Associated cis Element
- (2016) Vikram R. Paralkar et al. MOLECULAR CELL
- Enhancer Regulation of Transcriptional Bursting Parameters Revealed by Forced Chromatin Looping
- (2016) Caroline R. Bartman et al. MOLECULAR CELL
- Base-pair-resolution genome-wide mapping of active RNA polymerases using precision nuclear run-on (PRO-seq)
- (2016) Dig Bijay Mahat et al. Nature Protocols
- In Vivo Characterization of Linc-p21 Reveals Functional cis -Regulatory DNA Elements
- (2016) Abigail F. Groff et al. Cell Reports
- Activation of P-TEFb by Androgen Receptor-Regulated Enhancer RNAs in Castration-Resistant Prostate Cancer
- (2016) Yu Zhao et al. Cell Reports
- Deposition of 5-Methylcytosine on Enhancer RNAs Enables the Coactivator Function of PGC-1α
- (2016) Francesca Aguilo et al. Cell Reports
- Enhancer RNA-driven looping enhances the transcription of the long noncoding RNA DHRS4-AS1, a controller of the DHRS4 gene cluster
- (2016) Yingying Yang et al. Scientific Reports
- Functionally conserved enhancers with divergent sequences in distant vertebrates
- (2015) Song Yang et al. BMC GENOMICS
- Enhancer Evolution across 20 Mammalian Species
- (2015) Diego Villar et al. CELL
- Architectural and Functional Commonalities between Enhancers and Promoters
- (2015) Tae-Kyung Kim et al. CELL
- RNA Exosome-Regulated Long Non-Coding RNA Transcription Controls Super-Enhancer Activity
- (2015) Evangelos Pefanis et al. CELL
- Long ncRNA expression associates with tissue-specific enhancers
- (2015) Dubravka Vučićević et al. CELL CYCLE
- TNFα Signaling Exposes Latent Estrogen Receptor Binding Sites to Alter the Breast Cancer Cell Transcriptome
- (2015) Hector L. Franco et al. MOLECULAR CELL
- Bidirectional Transcription Arises from Two Distinct Hubs of Transcription Factor Binding and Active Chromatin
- (2015) Benjamin S. Scruggs et al. MOLECULAR CELL
- Transcription of Mammalian cis-Regulatory Elements Is Restrained by Actively Enforced Early Termination
- (2015) Liv M.I. Austenaa et al. MOLECULAR CELL
- Integrator mediates the biogenesis of enhancer RNAs
- (2015) Fan Lai et al. NATURE
- Multiplexable, locus-specific targeting of long RNAs with CRISPR-Display
- (2015) David M Shechner et al. NATURE METHODS
- Inflammation-sensitive super enhancers form domains of coordinately regulated enhancer RNAs
- (2015) Nasun Hah et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Transcription factor trapping by RNA in gene regulatory elements
- (2015) A. A. Sigova et al. SCIENCE
- Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells
- (2015) Erik Arner et al. SCIENCE
- The Human Nuclear Exosome Targeting Complex Is Loaded onto Newly Synthesized RNA to Direct Early Ribonucleolysis
- (2015) Michal Lubas et al. Cell Reports
- Convergent Transcription at Intragenic Super-Enhancers Targets AID-Initiated Genomic Instability
- (2014) Fei-Long Meng et al. CELL
- Enhancer Function: Mechanistic and Genome-Wide Insights Come Together
- (2014) Jennifer L. Plank et al. MOLECULAR CELL
- Enhancer RNA Facilitates NELF Release from Immediate Early Genes
- (2014) Katie Schaukowitch et al. MOLECULAR CELL
- An atlas of active enhancers across human cell types and tissues
- (2014) Robin Andersson et al. NATURE
- Quantitative genome-wide enhancer activity maps for five Drosophila species show functional enhancer conservation and turnover during cis-regulatory evolution
- (2014) Cosmas D Arnold et al. NATURE GENETICS
- Analysis of nascent RNA identifies a unified architecture of initiation regions at mammalian promoters and enhancers
- (2014) Leighton J Core et al. NATURE GENETICS
- Coupling mRNA processing with transcription in time and space
- (2014) David L. Bentley NATURE REVIEWS GENETICS
- Enhancer RNAs participate in androgen receptor-driven looping that selectively enhances gene activation
- (2014) C.-L. Hsieh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Nuclear stability and transcriptional directionality separate functionally distinct RNA species
- (2014) Robin Andersson et al. Nature Communications
- Tyrosine phosphorylation of RNA polymerase II CTD is associated with antisense promoter transcription and active enhancers in mammalian cells
- (2014) Nicolas Descostes et al. eLife
- RNAP II CTD tyrosine 1 performs diverse functions in vertebrate cells
- (2014) Jing-Ping Hsin et al. eLife
- lincRNAs: Genomics, Evolution, and Mechanisms
- (2013) Igor Ulitsky et al. CELL
- The RNA Polymerase II Carboxy-Terminal Domain (CTD) Code
- (2013) Dirk Eick et al. CHEMICAL REVIEWS
- Enhancer transcripts mark active estrogen receptor binding sites
- (2013) N. Hah et al. GENOME RESEARCH
- The landscape of RNA polymerase II transcription initiation in C. elegans reveals promoter and enhancer architectures
- (2013) R. A.- J. Chen et al. GENOME RESEARCH
- eRNAs Promote Transcription by Establishing Chromatin Accessibility at Defined Genomic Loci
- (2013) Kambiz Mousavi et al. MOLECULAR CELL
- Remodeling of the Enhancer Landscape during Macrophage Activation Is Coupled to Enhancer Transcription
- (2013) Minna U. Kaikkonen et al. MOLECULAR CELL
- Functional roles of enhancer RNAs for oestrogen-dependent transcriptional activation
- (2013) Wenbo Li et al. NATURE
- Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription
- (2013) Michael T. Y. Lam et al. NATURE
- Promoter directionality is controlled by U1 snRNP and polyadenylation signals
- (2013) Albert E. Almada et al. NATURE
- Activating RNAs associate with Mediator to enhance chromatin architecture and transcription
- (2013) Fan Lai et al. NATURE
- Precise Maps of RNA Polymerase Reveal How Promoters Direct Initiation and Pausing
- (2013) H. Kwak et al. SCIENCE
- Noncoding Transcription at Enhancers: General Principles and Functional Models
- (2012) Gioacchino Natoli et al. Annual Review of Genetics
- Controlling Long-Range Genomic Interactions at a Native Locus by Targeted Tethering of a Looping Factor
- (2012) Wulan Deng et al. CELL
- The RNA Pol II Elongation Factor Ell3 Marks Enhancers in ES Cells and Primes Future Gene Activation
- (2012) Chengqi Lin et al. CELL
- Characterization of genome-wide enhancer-promoter interactions reveals co-expression of interacting genes and modes of higher order chromatin organization
- (2012) Iouri Chepelev et al. CELL RESEARCH
- Threonine-4 of mammalian RNA polymerase II CTD is targeted by Polo-like kinase 3 and required for transcriptional elongation
- (2012) Corinna Hintermair et al. EMBO JOURNAL
- The RNA polymerase II CTD coordinates transcription and RNA processing
- (2012) J.-P. Hsin et al. GENES & DEVELOPMENT
- Intragenic Enhancers Act as Alternative Promoters
- (2012) Monika S. Kowalczyk et al. MOLECULAR CELL
- R Loops: From Transcription Byproducts to Threats to Genome Stability
- (2012) Andrés Aguilera et al. MOLECULAR CELL
- Modular regulatory principles of large non-coding RNAs
- (2012) Mitchell Guttman et al. NATURE
- Tissue-specific analysis of chromatin state identifies temporal signatures of enhancer activity during embryonic development
- (2012) Stefan Bonn et al. NATURE GENETICS
- CTD Tyrosine Phosphorylation Impairs Termination Factor Recruitment to RNA Polymerase II
- (2012) A. Mayer et al. SCIENCE
- Defining the Status of RNA Polymerase at Promoters
- (2012) Leighton J. Core et al. Cell Reports
- Conserved and non-conserved enhancers direct tissue specific transcription in ancient germ layer specific developmental control genes
- (2011) Sumantra Chatterjee et al. BMC DEVELOPMENTAL BIOLOGY
- A Rapid, Extensive, and Transient Transcriptional Response to Estrogen Signaling in Breast Cancer Cells
- (2011) Nasun Hah et al. CELL
- Enhancer and promoter interactions—long distance calls
- (2011) Ivan Krivega et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- H3K4 tri-methylation provides an epigenetic signature of active enhancers
- (2011) Aleksandra Pekowska et al. EMBO JOURNAL
- Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses
- (2011) M. N. Cabili et al. GENES & DEVELOPMENT
- Genomic Maps of Long Noncoding RNA Occupancy Reveal Principles of RNA-Chromatin Interactions
- (2011) Ci Chu et al. MOLECULAR CELL
- Reprogramming transcription by distinct classes of enhancers functionally defined by eRNA
- (2011) Dong Wang et al. NATURE
- Large-scale discovery of enhancers from human heart tissue
- (2011) Dalit May et al. NATURE GENETICS
- Transcription initiation platforms and GTF recruitment at tissue-specific enhancers and promoters
- (2011) Frederic Koch et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- PROMoter uPstream Transcripts share characteristics with mRNAs and are produced upstream of all three major types of mammalian promoters
- (2011) Pascal Preker et al. NUCLEIC ACIDS RESEARCH
- Antisense RNA polymerase II divergent transcripts are P-TEFb dependent and substrates for the RNA exosome
- (2011) R. A. Flynn et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Multiple functions of Ldb1 required for -globin activation during erythroid differentiation
- (2010) S.-H. Song et al. BLOOD
- Widespread transcription at neuronal activity-regulated enhancers
- (2010) Tae-Kyung Kim et al. NATURE
- A unique chromatin signature uncovers early developmental enhancers in humans
- (2010) Alvaro Rada-Iglesias et al. NATURE
- ChIP-Seq identification of weakly conserved heart enhancers
- (2010) Matthew J Blow et al. NATURE GENETICS
- Histone H3K27ac separates active from poised enhancers and predicts developmental state
- (2010) M. P. Creyghton et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Five-Vertebrate ChIP-seq Reveals the Evolutionary Dynamics of Transcription Factor Binding
- (2010) D. Schmidt et al. SCIENCE
- A Large Fraction of Extragenic RNA Pol II Transcription Sites Overlap Enhancers
- (2010) Francesca De Santa et al. PLOS BIOLOGY
- Histone modifications at human enhancers reflect global cell-type-specific gene expression
- (2009) Nathaniel D. Heintzman et al. NATURE
- Sepsid even-skipped Enhancers Are Functionally Conserved in Drosophila Despite Lack of Sequence Conservation
- (2008) Emily E. Hare et al. PLoS Genetics
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now