Principles of nucleosome recognition by chromatin factors and enzymes

Regulation of the Dot1 histone H3K79 methyltransferase by histone H4K16 acetylation

(2021) Marco Igor Valencia-Sánchez et al.   SCIENCE

JARID2 and AEBP2 regulate PRC2 in the presence of H2AK119ub1 and other histone modifications

(2021) Vignesh Kasinath et al.   SCIENCE

Linker histone defines structure and self-association behaviour of the 177 bp human chromatosome

(2021) Sai Wang et al.   Scientific Reports

PRMT6 methylation of RCC1 regulates mitosis, tumorigenicity, and radiation response of glioblastoma stem cells

(2021) Tianzhi Huang et al.   MOLECULAR CELL

BRCA1/BARD1 site-specific ubiquitylation of nucleosomal H2A is directed by BARD1

(2021) Samuel R. Witus et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Engineering nucleosomes for generating diverse chromatin assemblies

(2021) Zenita Adhireksan et al.   NUCLEIC ACIDS RESEARCH

Structural basis of nucleosomal histone H4 lysine 20 methylation by SET8 methyltransferase

(2021) Cheng-Han Ho et al.   Life Science Alliance

Structure of nucleosome-bound human BAF complex

(2020) Shuang He et al.   SCIENCE

Structural basis for COMPASS recognition of an H2B-ubiquitinated nucleosome

(2020) Evan J Worden et al.   eLife

Crystal Structure of the LSD1/CoREST Histone Demethylase Bound to Its Nucleosome Substrate

(2020) Sang-Ah Kim et al.   MOLECULAR CELL

Structure of SWI/SNF chromatin remodeller RSC bound to a nucleosome

(2020) Felix R. Wagner et al.   NATURE

Nucleosome-bound SOX2 and SOX11 structures elucidate pioneer factor function

(2020) Svetlana O. Dodonova et al.   NATURE

Mechanisms of OCT4-SOX2 motif readout on nucleosomes

(2020) Alicia K. Michael et al.   SCIENCE

Comprehensive nucleosome interactome screen establishes fundamental principles of nucleosome binding

(2020) Aleksandra Skrajna et al.   NUCLEIC ACIDS RESEARCH

Nucleosome-CHD4 chromatin remodeler structure maps human disease mutations

(2020) Lucas Farnung et al.   eLife

Structural basis for nucleosome-mediated inhibition of cGAS activity

(2020) Duanfang Cao et al.   CELL RESEARCH

The Molecular Basis of Tight Nuclear Tethering and Inactivation of cGAS

(2020) Baoyu Zhao et al.   NATURE

Bridging of DNA breaks activates PARP2–HPF1 to modify chromatin

(2020) Silvija Bilokapic et al.   NATURE

Structure of nucleosome-bound DNA methyltransferases DNMT3A and DNMT3B

(2020) Ting-Hai Xu et al.   NATURE

Structural basis for sequestration and autoinhibition of cGAS by chromatin

(2020) Sebastian Michalski et al.   NATURE

Structural mechanism of cGAS inhibition by the nucleosome

(2020) Ganesh R. Pathare et al.   NATURE

Structural basis for the inhibition of cGAS by nucleosomes

(2020) Tomoya Kujirai et al.   SCIENCE

Structural basis of nucleosome-dependent cGAS inhibition

(2020) Joshua A. Boyer et al.   SCIENCE

Near-atomic resolution structures of interdigitated nucleosome fibres

(2020) Zenita Adhireksan et al.   Nature Communications

Distinct Structures and Dynamics of Chromatosomes with Different Human Linker Histone Isoforms

(2020) Bing-Rui Zhou et al.   MOLECULAR CELL

Molecular basis of nucleosomal H3K36 methylation by NSD methyltransferases

(2020) Wanqiu Li et al.   NATURE

Mechanistic Insights into Regulation of the ALC1 Remodeler by the Nucleosome Acidic Patch

(2020) Laura C. Lehmann et al.   Cell Reports

Structural Basis for Recognition of Ubiquitylated Nucleosome by Dot1L Methyltransferase

(2019) Cathy J. Anderson et al.   Cell Reports

Structural insight into nucleosome transcription by RNA polymerase II with elongation factors

(2019) Haruhiko Ehara et al.   SCIENCE

Structures of the ISWI–nucleosome complex reveal a conserved mechanism of chromatin remodeling

(2019) Lijuan Yan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural basis of the crosstalk between histone H2B monoubiquitination and H3 lysine 79 methylation on nucleosome

(2019) Tonghui Yao et al.   CELL RESEARCH

Mechanism of Cross-talk between H2B Ubiquitination and H3 Methylation by Dot1L

(2019) Evan J. Worden et al.   CELL

Structural Basis of Dot1L Stimulation by Histone H2B Lysine 120 Ubiquitination

(2019) Marco Igor Valencia-Sánchez et al.   MOLECULAR CELL

DNA damage detection in nucleosomes involves DNA register shifting

(2019) Syota Matsumoto et al.   NATURE

Structure of the Human Core Centromeric Nucleosome Complex

(2019) Praveen Kumar Allu et al.   CURRENT BIOLOGY

Atomic resolution cryo-EM structure of a native-like CENP-A nucleosome aided by an antibody fragment

(2019) Bing-Rui Zhou et al.   Nature Communications

Structure and function of the Orc1 BAH-nucleosome complex

(2019) Pablo De Ioannes et al.   Nature Communications

Cryo-EM structures of remodeler-nucleosome intermediates suggest allosteric control through the nucleosome

(2019) Jean Paul Armache et al.   eLife

Structural basis of nucleosome recognition and modification by MLL methyltransferases

(2019) Han Xue et al.   NATURE

Structure of the inner kinetochore CCAN complex assembled onto a centromeric nucleosome

(2019) Kaige Yan et al.   NATURE

Structure of the RSC complex bound to the nucleosome

(2019) Youpi Ye et al.   SCIENCE

Retroviral integration into nucleosomes through DNA looping and sliding along the histone octamer

(2019) Marcus D. Wilson et al.   Nature Communications

Nucleosome and ubiquitin position Set2 to methylate H3K36

(2019) Silvija Bilokapic et al.   Nature Communications

Structural Basis of H2B Ubiquitination-Dependent H3K4 Methylation by COMPASS

(2019) Peter L. Hsu et al.   MOLECULAR CELL

Revisit of Reconstituted 30-Nm Nucleosome Arrays Reveals an Ensemble of Dynamic Structures

(2018) Bing-Rui Zhou et al.   JOURNAL OF MOLECULAR BIOLOGY

De novo mutation inRING1with epigenetic effects on neurodevelopment

(2018) Sarah B. Pierce et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis for ATP-dependent chromatin remodelling by the INO80 complex

(2018) Sebastian Eustermann et al.   NATURE

Structure of the chromatin remodelling enzyme Chd1 bound to a ubiquitinylated nucleosome

(2018) Ramasubramanian Sundaramoorthy et al.   eLife

Structure and dynamics of the yeast SWR1-nucleosome complex

(2018) Oliver Willhoft et al.   SCIENCE

Structure and Dynamics of a 197 bp Nucleosome in Complex with Linker Histone H1

(2017) Jan Bednar et al.   MOLECULAR CELL

Mechanism of chromatin remodelling revealed by the Snf2-nucleosome structure

(2017) Xiaoyu Liu et al.   NATURE

Nucleosome–Chd1 structure and implications for chromatin remodelling

(2017) Lucas Farnung et al.   NATURE

ISWI chromatin remodellers sense nucleosome modifications to determine substrate preference

(2017) Geoffrey P. Dann et al.   NATURE

Histone octamer rearranges to adapt to DNA unwrapping

(2017) Silvija Bilokapic et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural basis for spumavirus GAG tethering to chromatin

(2017) Paul Lesbats et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Histone octamer rearranges to adapt to DNA unwrapping

(2017) Silvija Bilokapic et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Recognition of the nucleosome by chromatin factors and enzymes

(2016) Robert K McGinty et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

The structural basis of modified nucleosome recognition by 53BP1

(2016) Marcus D. Wilson et al.   NATURE

Structural basis for histone H2B deubiquitination by the SAGA DUB module

(2016) M. T. Morgan et al.   SCIENCE

Structural Mechanisms of Nucleosome Recognition by Linker Histones

(2015) Bing-Rui Zhou et al.   MOLECULAR CELL

Structural basis for retroviral integration into nucleosomes

(2015) Daniel P. Maskell et al.   NATURE

Nucleosome Structure and Function

(2014) Robert K. McGinty et al.   CHEMICAL REVIEWS

Crystal structure of the PRC1 ubiquitylation module bound to the nucleosome

(2014) Robert K. McGinty et al.   NATURE

The role of the nucleosome acidic patch in modulating higher order chromatin structure

(2013) A. A. Kalashnikova et al.   Journal of the Royal Society Interface

A Conserved Mechanism for Centromeric Nucleosome Recognition by Centromere Protein CENP-C

(2013) H. Kato et al.   SCIENCE

Structural Basis of Silencing: Sir3 BAH Domain in Complex with a Nucleosome at 3.0 A Resolution

(2011) K.-J. Armache et al.   SCIENCE

Structure of RCC1 chromatin factor bound to the nucleosome core particle

(2010) Ravindra D. Makde et al.   NATURE