标题
Structural basis of nucleosome-dependent cGAS inhibition
作者
关键词
-
出版物
SCIENCE
Volume 370, Issue 6515, Pages 450-454
出版商
American Association for the Advancement of Science (AAAS)
发表日期
2020-09-11
DOI
10.1126/science.abd0609
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Estimation of high-order aberrations and anisotropic magnification from cryo-EM data sets in RELION-3.1
- (2020) Jasenko Zivanov et al. IUCrJ
- Comprehensive nucleosome interactome screen establishes fundamental principles of nucleosome binding
- (2020) Aleksandra Skrajna et al. NUCLEIC ACIDS RESEARCH
- Structural Basis for Recognition of Ubiquitylated Nucleosome by Dot1L Methyltransferase
- (2019) Cathy J. Anderson et al. Cell Reports
- The N-Terminal Domain of cGAS Determines Preferential Association with Centromeric DNA and Innate Immune Activation in the Nucleus
- (2019) Matteo Gentili et al. Cell Reports
- High-resolution structure determination of sub-100 kDa complexes using conventional cryo-EM
- (2019) Mark A. Herzik et al. Nature Communications
- cGAS in action: Expanding roles in immunity and inflammation
- (2019) Andrea Ablasser et al. SCIENCE
- Biophysics of Chromatin Dynamics
- (2019) Beat Fierz et al. Annual Review of Biophysics
- Human cGAS catalytic domain has an additional DNA-binding interface that enhances enzymatic activity and liquid-phase condensation
- (2019) Wei Xie et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Cytoplasmic DNA Sensor cGAS Promotes Mitotic Cell Death
- (2019) Christian Zierhut et al. CELL
- Chromatin‐bound cGAS is an inhibitor of DNA repair and hence accelerates genome destabilization and cell death
- (2019) Hui Jiang et al. EMBO JOURNAL
- Tight nuclear tethering of cGAS is essential for preventing autoreactivity
- (2019) Hannah E Volkman et al. eLife
- Structure of the Human cGAS–DNA Complex Reveals Enhanced Control of Immune Surveillance
- (2018) Wen Zhou et al. CELL
- DNA-induced liquid phase condensation of cGAS activates innate immune signaling
- (2018) Mingjian Du et al. SCIENCE
- Structural rearrangements of the histone octamer translocate DNA
- (2018) Silvija Bilokapic et al. Nature Communications
- Real-space refinement in PHENIX for cryo-EM and crystallography
- (2018) Pavel V. Afonine et al. Acta Crystallographica Section D-Structural Biology
- Nuclear cGAS suppresses DNA repair and promotes tumorigenesis
- (2018) Haipeng Liu et al. NATURE
- cGAS senses long and HMGB/TFAM-bound U-turn DNA by forming protein–DNA ladders
- (2017) Liudmila Andreeva et al. NATURE
- Addressing preferred specimen orientation in single-particle cryo-EM through tilting
- (2017) Yong Zi Tan et al. NATURE METHODS
- Recognition of the nucleosome by chromatin factors and enzymes
- (2016) Robert K McGinty et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Structural and biochemical characterization of the cell fate determining nucleotidyltransferase fold protein MAB21L1
- (2016) Carina C. de Oliveira Mann et al. Scientific Reports
- CTFFIND4: Fast and accurate defocus estimation from electron micrographs
- (2015) Alexis Rohou et al. JOURNAL OF STRUCTURAL BIOLOGY
- EMRinger: side chain–directed model and map validation for 3D cryo-electron microscopy
- (2015) Benjamin A Barad et al. NATURE METHODS
- Overlapping Patterns of Rapid Evolution in the Nucleic Acid Sensors cGAS and OAS1 Suggest a Common Mechanism of Pathogen Antagonism and Escape
- (2015) Dustin C. Hancks et al. PLoS Genetics
- Innate Immune Sensing and Signaling of Cytosolic Nucleic Acids
- (2014) Jiaxi Wu et al. Annual Review of Immunology
- Crystal structure of the PRC1 ubiquitylation module bound to the nucleosome
- (2014) Robert K. McGinty et al. NATURE
- Molecular evolutionary and structural analysis of the cytosolic DNA sensor cGAS and STING
- (2014) Xiaomei Wu et al. NUCLEIC ACIDS RESEARCH
- The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop
- (2014) Xu Zhang et al. Cell Reports
- Cyclic [G(2′,5′)pA(3′,5′)p] Is the Metazoan Second Messenger Produced by DNA-Activated Cyclic GMP-AMP Synthase
- (2013) Pu Gao et al. CELL
- Cyclic GMP-AMP Synthase Is Activated by Double-Stranded DNA-Induced Oligomerization
- (2013) Xin Li et al. IMMUNITY
- The role of the nucleosome acidic patch in modulating higher order chromatin structure
- (2013) A. A. Kalashnikova et al. Journal of the Royal Society Interface
- Structural mechanism of cytosolic DNA sensing by cGAS
- (2013) Filiz Civril et al. NATURE
- Cyclic GMP-AMP Is an Endogenous Second Messenger in Innate Immune Signaling by Cytosolic DNA
- (2012) J. Wu et al. SCIENCE
- Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway
- (2012) L. Sun et al. SCIENCE
- Nucleic Acid Recognition by the Innate Immune System
- (2011) Roman Barbalat et al. Annual Review of Immunology
- STING is a direct innate immune sensor of cyclic di-GMP
- (2011) Dara L. Burdette et al. NATURE
- Structural Basis of Silencing: Sir3 BAH Domain in Complex with a Nucleosome at 3.0 A Resolution
- (2011) K.-J. Armache et al. SCIENCE
- Structure and Scm3-mediated assembly of budding yeast centromeric nucleosomes
- (2011) Mekonnen Lemma Dechassa et al. Nature Communications
- Precise beam-tilt alignment and collimation are required to minimize the phase error associated with coma in high-resolution cryo-EM
- (2010) Robert M. Glaeser et al. JOURNAL OF STRUCTURAL BIOLOGY
- Structure of RCC1 chromatin factor bound to the nucleosome core particle
- (2010) Ravindra D. Makde et al. NATURE
- MolProbity: all-atom structure validation for macromolecular crystallography
- (2009) Vincent B. Chen et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- The Adaptor Protein MITA Links Virus-Sensing Receptors to IRF3 Transcription Factor Activation
- (2008) Bo Zhong et al. IMMUNITY
- STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling
- (2008) Hiroki Ishikawa et al. NATURE
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started