Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

Genome-wide association analyses of chronotype in 697,828 individuals provides insights into circadian rhythms

(2019) Samuel E. Jones et al.   Nature Communications

Genome-wide association study of offspring birth weight in 86 577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics

(2018) Robin N Beaumont et al.   HUMAN MOLECULAR GENETICS

Using structural equation modelling to jointly estimate maternal and fetal effects on birthweight in the UK Biobank

(2018) Nicole M Warrington et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types

(2018) Hilary K. Finucane et al.   NATURE GENETICS

A Common Allele in FGF21 Associated with Sugar Intake Is Associated with Body Shape, Lower Total Body-Fat Percentage, and Higher Blood Pressure

(2018) Timothy M. Frayling et al.   Cell Reports

Implicating candidate genes at GWAS signals by leveraging topologically associating domains

(2017) Gregory P Way et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Expression quantitative trait loci (eQTLs) in human placentas suggest developmental origins of complex diseases

(2017) Shouneng Peng et al.   HUMAN MOLECULAR GENETICS

Identification of 153 new loci associated with heel bone mineral density and functional involvement of GPC6 in osteoporosis

(2017) John P Kemp et al.   NATURE GENETICS

Genetic Associations with Gestational Duration and Spontaneous Preterm Birth

(2017) Ge Zhang et al.   NEW ENGLAND JOURNAL OF MEDICINE

Height associated variants demonstrate assortative mating in human populations

(2017) Xiaoyin Li et al.   Scientific Reports

Comparison of associations of maternal peri-pregnancy and paternal anthropometrics with child anthropometrics from birth through age 7 y assessed in the Danish National Birth Cohort

(2016) Thorkild IA Sørensen et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis

(2016) Jie Zheng et al.   BIOINFORMATICS

Can genetic evidence help us to understand the fetal origins of type 2 diabetes?

(2016) Rachel M. Freathy   DIABETOLOGIA

Low birthweight and risk of type 2 diabetes: a Mendelian randomisation study

(2016) Tiange Wang et al.   DIABETOLOGIA

Consistent Estimation in Mendelian Randomization with Some Invalid Instruments Using a Weighted Median Estimator

(2016) Jack Bowden et al.   GENETIC EPIDEMIOLOGY

Genetic Evidence for Causal Relationships Between Maternal Obesity-Related Traits and Birth Weight

(2016) Jessica Tyrrell et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Genome-wide associations for birth weight and correlations with adult disease

(2016) Momoko Horikoshi et al.   NATURE

Integrative approaches for large-scale transcriptome-wide association studies

(2016) Alexander Gusev et al.   NATURE GENETICS

Height, body mass index, and socioeconomic status: mendelian randomisation study in UK Biobank

(2016) Jessica Tyrrell et al.   BMJ-British Medical Journal

Height, body mass index, and socioeconomic status: mendelian randomisation study in UK Biobank

(2016) Jessica Tyrrell et al.   BMJ-British Medical Journal

Using published data in Mendelian randomization: a blueprint for efficient identification of causal risk factors

(2015) Stephen Burgess et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression

(2015) J. Bowden et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

An atlas of genetic correlations across human diseases and traits

(2015) Brendan Bulik-Sullivan et al.   NATURE GENETICS

LD Score regression distinguishes confounding from polygenicity in genome-wide association studies

(2015) Brendan K Bulik-Sullivan et al.   NATURE GENETICS

Efficient Bayesian mixed-model analysis increases association power in large cohorts

(2015) Po-Ru Loh et al.   NATURE GENETICS

The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans

(2015) et al.   SCIENCE

Assessing the Causal Relationship of Maternal Height on Birth Size and Gestational Age at Birth: A Mendelian Randomization Analysis

(2015) Ge Zhang et al.   PLOS MEDICINE

Resolving the Effects of Maternal and Offspring Genotype on Dyadic Outcomes in Genome Wide Complex Trait Analysis (“M-GCTA”)

(2014) Lindon J. Eaves et al.   BEHAVIOR GENETICS

Defining the role of common variation in the genomic and biological architecture of adult human height

(2014) Andrew R Wood et al.   NATURE GENETICS

Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics

(2014) Claudia Giambartolomei et al.   PLoS Genetics

A Central Role for GRB10 in Regulation of Islet Function in Man

(2014) Inga Prokopenko et al.   PLoS Genetics

Efficient Design for Mendelian Randomization Studies: Subsample and 2-Sample Instrumental Variable Estimators

(2013) B. L. Pierce et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Topological domains in mammalian genomes identified by analysis of chromatin interactions

(2012) Jesse R. Dixon et al.   NATURE

New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism

(2012) Momoko Horikoshi et al.   NATURE GENETICS

Zhou et al. reply

(2012) Kaixin Zhou et al.   NATURE GENETICS

Improved whole-chromosome phasing for disease and population genetic studies

(2012) Olivier Delaneau et al.   NATURE METHODS

Mechanisms underlying the developmental origins of disease

(2012) Malgorzata S. Martin-Gronert et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

Prenatal Famine and Adult Health

(2011) L.H. Lumey et al.   Annual Review of Public Health

GCTA: A Tool for Genome-wide Complex Trait Analysis

(2010) Jian Yang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Robust relationship inference in genome-wide association studies

(2010) Ani Manichaikul et al.   BIOINFORMATICS

METAL: fast and efficient meta-analysis of genomewide association scans

(2010) C. J. Willer et al.   BIOINFORMATICS

GWAMA: software for genome-wide association meta-analysis

(2010) Reedik Mägi et al.   BMC BIOINFORMATICS

Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight

(2010) Rachel M Freathy et al.   NATURE GENETICS

Common Inherited Variation in Mitochondrial Genes Is Not Enriched for Associations with Type 2 Diabetes or Related Glycemic Traits

(2010) Ayellet V. Segrè et al.   PLoS Genetics

Hyperglycemia and Adverse Pregnancy Outcomes

(2008)   NEW ENGLAND JOURNAL OF MEDICINE