标题
A large electronic-health-record-based genome-wide study of serum lipids
作者
关键词
-
出版物
NATURE GENETICS
Volume 50, Issue 3, Pages 401-413
出版商
Springer Nature
发表日期
2018-02-28
DOI
10.1038/s41588-018-0064-5
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Exome chip meta-analysis identifies novel loci and East Asian–specific coding variants that contribute to lipid levels and coronary artery disease
- (2017) Xiangfeng Lu et al. NATURE GENETICS
- Exome-wide association study of plasma lipids in >300,000 individuals
- (2017) Dajiang J Liu et al. NATURE GENETICS
- Model-free Estimation of Recent Genetic Relatedness
- (2016) Matthew P. Conomos et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Analysis with the exome array identifies multiple new independent variants in lipid loci
- (2016) Stavroula Kanoni et al. HUMAN MOLECULAR GENETICS
- Genome-wide association study of serum lipids confirms previously reported associations as well as new associations of common SNPs within PCSK7 gene with triglyceride
- (2016) Makoto Kurano et al. JOURNAL OF HUMAN GENETICS
- Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant inANGPTL4determining fasting TG levels
- (2016) Elisabeth M van Leeuwen et al. JOURNAL OF MEDICAL GENETICS
- Reference-based phasing using the Haplotype Reference Consortium panel
- (2016) Po-Ru Loh et al. NATURE GENETICS
- Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation
- (2016) Thomas J Hoffmann et al. NATURE GENETICS
- Next-generation genotype imputation service and methods
- (2016) Sayantan Das et al. NATURE GENETICS
- Distribution and clinical impact of functional variants in 50,726 whole-exome sequences from the DiscovEHR study
- (2016) Frederick E. Dewey et al. SCIENCE
- Meta-analysis of lipid-traits in Hispanics identifies novel loci, population-specific effects and tissue-specific enrichment of eQTLs
- (2016) Jennifer E. Below et al. Scientific Reports
- Disrupting the circadian clock: Gene-specific effects on aging, cancer, and other phenotypes
- (2016) Elizabeth A. Yu et al. Aging-US
- Cholesterol Transport through Lysosome-Peroxisome Membrane Contacts
- (2015) Bei-Bei Chu et al. CELL
- Genetic Susceptibility to Lipid Levels and Lipid Change Over Time and Risk of Incident Hyperlipidemia in Chinese PopulationsCLINICAL PERSPECTIVE
- (2015) Xiangfeng Lu et al. Circulation-Cardiovascular Genetics
- Genotyping Informatics and Quality Control for 100,000 Subjects in the Genetic Epidemiology Research on Adult Health and Aging (GERA) Cohort
- (2015) Mark N. Kvale et al. GENETICS
- Characterizing Race/Ethnicity and Genetic Ancestry for 100,000 Subjects in the Genetic Epidemiology Research on Adult Health and Aging (GERA) Cohort
- (2015) Yambazi Banda et al. GENETICS
- Genetic meta-analysis of 15,901 African Americans identifies variation inEXOC3L1is associated with HDL concentration
- (2015) Matthew B. Lanktree et al. JOURNAL OF LIPID RESEARCH
- Glucagon receptor antagonism induces increased cholesterol absorption
- (2015) Hong-Ping Guan et al. JOURNAL OF LIPID RESEARCH
- A metabolomic study of adipose tissue in mice with a disruption of the circadian system
- (2015) C. Castro et al. Molecular BioSystems
- The impact of low-frequency and rare variants on lipid levels
- (2015) Ida Surakka et al. NATURE GENETICS
- Genome sequencing elucidates Sardinian genetic architecture and augments association analyses for lipid and blood inflammatory markers
- (2015) Carlo Sidore et al. NATURE GENETICS
- Efficient Bayesian mixed-model analysis increases association power in large cohorts
- (2015) Po-Ru Loh et al. NATURE GENETICS
- The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans
- (2015) et al. SCIENCE
- UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age
- (2015) Cathie Sudlow et al. PLOS MEDICINE
- Genetic Susceptibility to Lipid Levels and Lipid Change Over Time and Risk of Incident Hyperlipidemia in Chinese PopulationsCLINICAL PERSPECTIVE
- (2015) Xiangfeng Lu et al. Circulation-Cardiovascular Genetics
- Genotyping Informatics and Quality Control for 100,000 Subjects in the Genetic Epidemiology Research on Adult Health and Aging (GERA) Cohort
- (2015) Mark N. Kvale et al. GENETICS
- Characterizing Race/Ethnicity and Genetic Ancestry for 100,000 Subjects in the Genetic Epidemiology Research on Adult Health and Aging (GERA) Cohort
- (2015) Yambazi Banda et al. GENETICS
- Second-generation PLINK: rising to the challenge of larger and richer datasets
- (2015) Christopher C Chang et al. GigaScience
- Effects of Long-Term Averaging of Quantitative Blood Pressure Traits on the Detection of Genetic Associations
- (2014) Santhi K. Ganesh et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Fast and accurate imputation of summary statistics enhances evidence of functional enrichment
- (2014) Bogdan Pasaniuc et al. BIOINFORMATICS
- Multiple Associated Variants Increase the Heritability Explained for Plasma Lipids and Coronary Artery Disease
- (2014) H. Tada et al. Circulation-Cardiovascular Genetics
- Genome-wide association study in Chinese identifies novel loci for blood pressure and hypertension
- (2014) Xiangfeng Lu et al. HUMAN MOLECULAR GENETICS
- Sex-specific Association of the Zinc Finger Protein 259 rs2075290 Polymorphism and Serum Lipid Levels
- (2014) Lynn Htet Htet Aung et al. International Journal of Medical Sciences
- Genome-wide Characterization of Shared and Distinct Genetic Components that Influence Blood Lipid Levels in Ethnically Diverse Human Populations
- (2013) Marc A. Coram et al. AMERICAN JOURNAL OF HUMAN GENETICS
- THOC5: a novel gene involved in HDL-cholesterol metabolism
- (2013) Maria Keller et al. JOURNAL OF LIPID RESEARCH
- Heritability of metabolic syndrome traits in a large population-based sample
- (2013) Jenny van Dongen et al. JOURNAL OF LIPID RESEARCH
- Transcriptome and genome sequencing uncovers functional variation in humans
- (2013) Tuuli Lappalainen et al. NATURE
- Discovery and refinement of loci associated with lipid levels
- (2013) Cristen J Willer et al. NATURE GENETICS
- Systematic identification of trans eQTLs as putative drivers of known disease associations
- (2013) Harm-Jan Westra et al. NATURE GENETICS
- Fat Depots, Free Fatty Acids, and Dyslipidemia
- (2013) Jon Ebbert et al. Nutrients
- GENCODE: The reference human genome annotation for The ENCODE Project
- (2012) J. Harrow et al. GENOME RESEARCH
- Fast and accurate genotype imputation in genome-wide association studies through pre-phasing
- (2012) Bryan Howie et al. NATURE GENETICS
- Evaluation of the Metabochip Genotyping Array in African Americans and Implications for Fine Mapping of GWAS-Identified Loci: The PAGE Study
- (2012) Steven Buyske et al. PLoS One
- Multi-Ethnic Analysis of Lipid-Associated Loci: The NHLBI CARe Project
- (2012) Kiran Musunuru et al. PLoS One
- Gene-Centric Meta-Analysis of Lipid Traits in African, East Asian and Hispanic Populations
- (2012) Clara C. Elbers et al. PLoS One
- A Genome-Wide Association Meta-Analysis of Circulating Sex Hormone–Binding Globulin Reveals Multiple Loci Implicated in Sex Steroid Hormone Regulation
- (2012) Andrea D. Coviello et al. PLoS Genetics
- Estimating Missing Heritability for Disease from Genome-wide Association Studies
- (2011) Sang Hong Lee et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Random-Effects Model Aimed at Discovering Associations in Meta-Analysis of Genome-wide Association Studies
- (2011) Buhm Han et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Genomic inflation factors under polygenic inheritance
- (2011) Jian Yang et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- A survey of the genetics of stomach, liver, and adipose gene expression from a morbidly obese cohort
- (2011) D. M. Greenawalt et al. GENOME RESEARCH
- Design and coverage of high throughput genotyping arrays optimized for individuals of East Asian, African American, and Latino race/ethnicity using imputation and a novel hybrid SNP selection algorithm
- (2011) Thomas J. Hoffmann et al. GENOMICS
- Next generation genome-wide association tool: Design and coverage of a high-throughput European-optimized SNP array
- (2011) Thomas J. Hoffmann et al. GENOMICS
- Low density lipoprotein cholesterol is inversely correlated with abdominal visceral fat area: a magnetic resonance imaging study
- (2011) Michel R Hoenig et al. Lipids in Health and Disease
- Mapping and analysis of chromatin state dynamics in nine human cell types
- (2011) Jason Ernst et al. NATURE
- A linear complexity phasing method for thousands of genomes
- (2011) Olivier Delaneau et al. NATURE METHODS
- HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants
- (2011) L. D. Ward et al. NUCLEIC ACIDS RESEARCH
- Deficient of a Clock Gene, Brain and Muscle Arnt-Like Protein-1 (BMAL1), Induces Dyslipidemia and Ectopic Fat Formation
- (2011) Shigeki Shimba et al. PLoS One
- Genotype Imputation with Thousands of Genomes
- (2011) Bryan Howie et al. G3-Genes Genomes Genetics
- GCTA: A Tool for Genome-wide Complex Trait Analysis
- (2010) Jian Yang et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Biological, clinical and population relevance of 95 loci for blood lipids
- (2010) Tanya M. Teslovich et al. NATURE
- Genotype imputation for genome-wide association studies
- (2010) Jonathan Marchini et al. NATURE REVIEWS GENETICS
- PharmGKB very important pharmacogene: SLCO1B1
- (2010) Connie Oshiro et al. Pharmacogenetics and Genomics
- Trait-Associated SNPs Are More Likely to Be eQTLs: Annotation to Enhance Discovery from GWAS
- (2010) Dan L. Nicolae et al. PLoS Genetics
- Genotype-Imputation Accuracy across Worldwide Human Populations
- (2009) Lucy Huang et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Genome-wide association meta-analysis for total serum bilirubin levels
- (2009) A. D. Johnson et al. HUMAN MOLECULAR GENETICS
- A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies
- (2009) Bryan N. Howie et al. PLoS Genetics
- Personal genomes: The case of the missing heritability
- (2008) Brendan Maher NATURE
- SLCO1B1Variants and Statin-Induced Myopathy — A Genomewide Study
- (2008) NEW ENGLAND JOURNAL OF MEDICINE
- Mapping the Genetic Architecture of Gene Expression in Human Liver
- (2008) Eric E Schadt et al. PLOS BIOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now