标题
Genetic Constructs for the Control of Astrocytes’ Activity
作者
关键词
-
出版物
Cells
Volume 10, Issue 7, Pages 1600
出版商
MDPI AG
发表日期
2021-06-25
DOI
10.3390/cells10071600
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- AAV Targeting of Glial Cell Types in the Central and Peripheral Nervous System and Relevance to Human Gene Therapy
- (2021) Simon J. O’Carroll et al. Frontiers in Molecular Neuroscience
- Prenatal ethanol exposure impairs the formation of radial glial fibers and promotes the transformation of GFAPδ‑positive radial glial cells into astrocytes
- (2021) Yu Li et al. Molecular Medicine Reports
- Reactive astrocyte nomenclature, definitions, and future directions
- (2021) Carole Escartin et al. NATURE NEUROSCIENCE
- Optogenetic and chemogenetic modulation of astroglial secretory phenotype
- (2021) Alla B. Salmina et al. REVIEWS IN THE NEUROSCIENCES
- Characterization of Subcellular Organelles in Cortical Perisynaptic Astrocytes
- (2021) Amina Aboufares El Alaoui et al. Frontiers in Cellular Neuroscience
- Astrocytes in Alzheimer’s Disease: Pathological Significance and Molecular Pathways
- (2021) Pranav Preman et al. Cells
- The effects of trifluoperazine on brain edema, aquaporin-4 expression and metabolic markers during the acute phase of stroke using photothrombotic mouse model
- (2021) Nicole J. Sylvain et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Advances in Applying Computer-Aided Drug Design for Neurodegenerative Diseases
- (2021) Mootaz M. Salman et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Functional enhancer elements drive subclass-selective expression from mouse to primate neocortex
- (2021) John K. Mich et al. Cell Reports
- Astrocyte Diversity: Current Insights and Future Directions
- (2020) Thomas Westergard et al. NEUROCHEMICAL RESEARCH
- Targeting Aquaporin-4 Subcellular Localization to Treat Central Nervous System Edema
- (2020) Philip Kitchen et al. CELL
- Stem cells and vascular dementia: from basic science to the clinic
- (2020) Wenxia Jiang et al. CELL AND TISSUE BANKING
- AAV Capsid-Promoter Interactions Determine CNS Cell-Selective Gene Expression In Vivo
- (2020) Sara K. Powell et al. MOLECULAR THERAPY
- Reversing a model of Parkinson’s disease with in situ converted nigral neurons
- (2020) Hao Qian et al. NATURE
- Lactate enhances Arc/arg3.1 expression through hydroxycarboxylic acid receptor 1-β-arrestin2 pathway in astrocytes
- (2020) Kaiyang Ma et al. NEUROPHARMACOLOGY
- Activation of a neural stem cell transcriptional program in parenchymal astrocytes
- (2020) Jens P Magnusson et al. eLife
- Glial restricted precursor cells in central nervous system disorders: Current applications and future perspectives
- (2020) Joana Martins‐Macedo et al. GLIA
- Dissecting Neuronal Activation on a Brain-Wide Scale With Immediate Early Genes
- (2020) Alessandra Franceschini et al. Frontiers in Neuroscience
- Design and Validation of a Human Brain Endothelial Microvessel-on-a-Chip Open Microfluidic Model Enabling Advanced Optical Imaging
- (2020) Mootaz M. Salman et al. Frontiers in Bioengineering and Biotechnology
- Crossing the blood-brain barrier with AAV vectors
- (2020) Dan Liu et al. METABOLIC BRAIN DISEASE
- The Paradox of Astroglial Ca2 + Signals at the Interface of Excitation and Inhibition
- (2020) Laura C. Caudal et al. Frontiers in Cellular Neuroscience
- Melanopsin for precise optogenetic activation of astrocyte-neuron networks
- (2019) Sara Mederos et al. GLIA
- Astrocyte Heterogeneity: Impact to Brain Aging and Disease
- (2019) Isadora Matias et al. Frontiers in Aging Neuroscience
- Astrocyte-selective AAV gene therapy through the endogenous GFAP promoter results in robust transduction in the rat spinal cord following injury
- (2019) Jarred M. Griffin et al. GENE THERAPY
- CRAC channels regulate astrocyte Ca2+ signaling and gliotransmitter release to modulate hippocampal GABAergic transmission
- (2019) Anna B. Toth et al. Science Signaling
- The energetic brain ‐ A review from students to students
- (2019) M.P. Bordone et al. JOURNAL OF NEUROCHEMISTRY
- The Appropriate Marker for Astrocytes: Comparing the Distribution and Expression of Three Astrocytic Markers in Different Mouse Cerebral Regions
- (2019) Zengli Zhang et al. Biomed Research International
- Astroglial atrophy in Alzheimer’s disease
- (2019) Alexei Verkhratsky et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- Development of Efficient AAV2/DJ-Based Viral Vectors to Selectively Downregulate the Expression of Neuronal or Astrocytic Target Proteins in the Rat Central Nervous System
- (2019) Charlotte Jollé et al. Frontiers in Molecular Neuroscience
- Astrocytes: Role and Functions in Brain Pathologies
- (2019) Rosalba Siracusa et al. Frontiers in Pharmacology
- Melanopsin and the Intrinsically Photosensitive Retinal Ganglion Cells: Biophysics to Behavior
- (2019) Michael Tri H. Do NEURON
- Delivering genes across the blood-brain barrier: LY6A, a novel cellular receptor for AAV-PHP.B capsids
- (2019) Qin Huang et al. PLoS One
- Co-stimulation with IL-1β and TNF-α induces an inflammatory reactive astrocyte phenotype with neurosupportive characteristics in a human pluripotent stem cell model system
- (2019) Tanja Hyvärinen et al. Scientific Reports
- Expression Patterns of Inducible Cre Recombinase Driven by Differential Astrocyte-Specific Promoters in Transgenic Mouse Lines
- (2019) Neng-Yuan Hu et al. Neuroscience Bulletin
- Cerebral Organoids Repair Ischemic Stroke Brain Injury
- (2019) Shu-Na Wang et al. Translational Stroke Research
- Viral Strategies for Targeting the Central and Peripheral Nervous Systems
- (2018) Claire N. Bedbrook et al. Annual Review of Neuroscience
- Astrocytic Activation Generates De Novo Neuronal Potentiation and Memory Enhancement
- (2018) Adar Adamsky et al. CELL
- Hippocampal Radial Glial Subtypes and Their Neurogenic Potential in Human Fetuses and Healthy and Alzheimer’s Disease Adults
- (2018) Sara Cipriani et al. CEREBRAL CORTEX
- Marked Diversity of Unique Cortical Enhancers Enables Neuron-Specific Tools by Enhancer-Driven Gene Expression
- (2018) Stefan Blankvoort et al. CURRENT BIOLOGY
- The cysteine residue of glial fibrillary acidic protein is a critical target for lipoxidation and required for efficient network organization
- (2018) Álvaro Viedma-Poyatos et al. FREE RADICAL BIOLOGY AND MEDICINE
- Multiple Lines of Evidence Indicate That Gliotransmission Does Not Occur under Physiological Conditions
- (2018) Todd A. Fiacco et al. JOURNAL OF NEUROSCIENCE
- Gliotransmitters and cytokines in the control of blood-brain barrier permeability
- (2018) Elena D. Osipova et al. REVIEWS IN THE NEUROSCIENCES
- Functional Roles of Astrocyte Calcium Elevations: From Synapses to Behavior
- (2018) Sónia Guerra-Gomes et al. Frontiers in Cellular Neuroscience
- Neuronal activity determines distinct gliotransmitter release from a single astrocyte
- (2018) Ana Covelo et al. eLife
- Enhancement of Astroglial Aerobic Glycolysis by Extracellular Lactate-Mediated Increase in cAMP
- (2018) Nina Vardjan et al. Frontiers in Molecular Neuroscience
- Expression of radial glial markers (GFAP, BLBP and GS) during telencephalic development in the catshark (Scyliorhinus canicula)
- (2018) A. Docampo-Seara et al. Brain Structure & Function
- Astrocyte Heterogeneity in the Adult Central Nervous System
- (2018) Sean J. Miller Frontiers in Cellular Neuroscience
- Engineered AAVs for efficient noninvasive gene delivery to the central and peripheral nervous systems
- (2017) Ken Y Chan et al. NATURE NEUROSCIENCE
- Neural Circuit-Specialized Astrocytes: Transcriptomic, Proteomic, Morphological, and Functional Evidence
- (2017) Hua Chai et al. NEURON
- Chloride conducting light activated channel GtACR2 can produce both cessation of firing and generation of action potentials in cortical neurons in response to light
- (2017) A.Y. Malyshev et al. NEUROSCIENCE LETTERS
- Cellular selectivity of AAV serotypes for gene delivery in neurons and astrocytes by neonatal intracerebroventricular injection
- (2017) Sean L. Hammond et al. PLoS One
- Blood-brain barrier-supported neurogenesis in healthy and diseased brain
- (2017) Elena A. Pozhilenkova et al. REVIEWS IN THE NEUROSCIENCES
- Glia-derived ATP inversely regulates excitability of pyramidal and CCK-positive neurons
- (2017) Zhibing Tan et al. Nature Communications
- The role of astrocytes in amyloid production and Alzheimer's disease
- (2017) Georgia R. Frost et al. Open Biology
- A MicroRNA124 Target Sequence Restores Astrocyte Specificity of gfaABC 1 D-Driven Transgene Expression in AAV-Mediated Gene Transfer
- (2017) Grit Taschenberger et al. Molecular Therapy-Nucleic Acids
- AAV-Mediated Astrocyte-Specific Gene Expression under Human ALDH1L1 Promoter in Mouse Thalamus
- (2017) Wuhyun Koh et al. Experimental Neurobiology
- RAGE and Alzheimer's Disease: A Progression Factor for Amyloid-β-Induced Cellular Perturbation?
- (2017) Shi Du Yan et al. JOURNAL OF ALZHEIMERS DISEASE
- Systemic application of AAV vectors targeting GFAP-expressing astrocytes in Z -Q175-KI Huntington's disease mice
- (2016) Tatyana Vagner et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- Cre-dependent selection yields AAV variants for widespread gene transfer to the adult brain
- (2016) Benjamin E Deverman et al. NATURE BIOTECHNOLOGY
- New Transgenic Mouse Lines for Selectively Targeting Astrocytes and Studying Calcium Signals in Astrocyte Processes In Situ and In Vivo
- (2016) Rahul Srinivasan et al. NEURON
- A Designer AAV Variant Permits Efficient Retrograde Access to Projection Neurons
- (2016) D. Gowanlock R. Tervo et al. NEURON
- Viral Vector-Based Dissection of Marmoset GFAP Promoter in Mouse and Marmoset Brains
- (2016) Yoichiro Shinohara et al. PLoS One
- Astrocytes regulate heterogeneity of presynaptic strengths in hippocampal networks
- (2016) Mathieu Letellier et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Recombinant Adeno-Associated Virus Serotype 6 (rAAV6) Potently and Preferentially Transduces Rat Astrocytes In vitro and In vivo
- (2016) Alexandra L. Schober et al. Frontiers in Cellular Neuroscience
- Transcriptional activity of novel ALDH1L1 promoters in the rat brain following AAV vector-mediated gene transfer
- (2016) Janitha M Mudannayake et al. Molecular Therapy-Methods & Clinical Development
- Glial fibrillary acidic protein (GFAP) and the astrocyte intermediate filament system in diseases of the central nervous system
- (2015) Elly M Hol et al. CURRENT OPINION IN CELL BIOLOGY
- GFAP and vimentin deficiency alters gene expression in astrocytes and microglia in wild-type mice and changes the transcriptional response of reactive glia in mouse model for Alzheimer's disease
- (2015) Willem Kamphuis et al. GLIA
- Glycolysis-mediated control of blood-brain barrier development and function
- (2015) Alla B. Salmina et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Specific gene expression in mouse cortical astrocytes is mediated by a 1740bp-GFAP promoter-driven combined adeno-associated virus2/5/7/8/9
- (2015) Xiandong Meng et al. NEUROSCIENCE LETTERS
- Comparative analyses of adeno-associated viral vector serotypes 1, 2, 5, 8 and 9 in marmoset, mouse and macaque cerebral cortex
- (2015) Akiya Watakabe et al. NEUROSCIENCE RESEARCH
- Glial fibrillary acidic protein: from intermediate filament assembly and gliosis to neurobiomarker
- (2015) Zhihui Yang et al. TRENDS IN NEUROSCIENCES
- A Novel Subtype of Astrocytes Expressing TRPV4 (Transient Receptor Potential Vanilloid 4) Regulates Neuronal Excitability via Release of Gliotransmitters
- (2014) Koji Shibasaki et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Histone acetylation in astrocytes suppresses GFAP and stimulates a reorganization of the intermediate filament network
- (2014) Regina Kanski et al. JOURNAL OF CELL SCIENCE
- Astrocytic modulation of blood brain barrier: perspectives on Parkinson’s disease
- (2014) Ricardo Cabezas et al. Frontiers in Cellular Neuroscience
- Altered expression of Alzheimer’s disease-related genes in the cerebellum of autistic patients: a model for disrupted brain connectome and therapy
- (2014) F Zeidán-Chuliá et al. Cell Death & Disease
- Optimization of AAV expression cassettes to improve packaging capacity and transgene expression in neurons
- (2014) Jun-Hyeok Choi et al. Molecular Brain
- Potassium Buffering in the Neurovascular Unit: Models and Sensitivity Analysis
- (2013) Alexandra Witthoft et al. BIOPHYSICAL JOURNAL
- Evidence that pericytes regulate aquaporin-4 polarization in mouse cortical astrocytes
- (2013) Georg Andreas Gundersen et al. Brain Structure & Function
- Intracerebroventricular Injection of Adeno-Associated Virus 6 and 9 Vectors for Cell Type–Specific Transgene Expression in the Spinal Cord
- (2013) Elisabeth Dirren et al. HUMAN GENE THERAPY
- Imaging calcium microdomains within entire astrocyte territories and endfeet with GCaMPs expressed using adeno-associated viruses
- (2013) Eiji Shigetomi et al. JOURNAL OF GENERAL PHYSIOLOGY
- Glial fibrillary acidic protein isoform expression in plaque related astrogliosis in Alzheimer's disease
- (2013) Willem Kamphuis et al. NEUROBIOLOGY OF AGING
- Capsid Serotype and Timing of Injection Determines AAV Transduction in the Neonatal Mice Brain
- (2013) Paramita Chakrabarty et al. PLoS One
- Glial Promoter Selectivity following AAV-Delivery to the Immature Brain
- (2013) Georg von Jonquieres et al. PLoS One
- Analysis of Transduction Efficiency, Tropism and Axonal Transport of AAV Serotypes 1, 2, 5, 6, 8 and 9 in the Mouse Brain
- (2013) Dominik F. Aschauer et al. PLoS One
- Correction: Alternative mRNA Splicing from the Glial Fibrillary Acidic Protein (GFAP) Gene Generates Isoforms with Distinct Subcellular mRNA Localization Patterns in Astrocytes
- (2013) Rune Thomsen et al. PLoS One
- The Evolutionary Relationship between Microbial Rhodopsins and Metazoan Rhodopsins
- (2013) Libing Shen et al. TheScientificWorldJOURNAL
- Heterosynaptic long-term depression mediated by ATP released from astrocytes
- (2012) Jiadong Chen et al. GLIA
- GFAPδ Expression in Glia of the Developmental and Adolescent Mouse Brain
- (2012) Carlyn Mamber et al. PLoS One
- The Microbial Opsin Family of Optogenetic Tools
- (2011) Feng Zhang et al. CELL
- Adenosine kinase as a target for therapeutic antisense strategies in epilepsy
- (2011) Panos Theofilas et al. EPILEPSIA
- Microarray analysis of the astrocyte transcriptome in the aging brain: relationship to Alzheimer's pathology and APOE genotype
- (2011) Julie E. Simpson et al. NEUROBIOLOGY OF AGING
- Structural Remodeling of Astrocytes in the Injured CNS
- (2011) Daniel Sun et al. NEUROSCIENTIST
- S100B and APP Promote a Gliocentric Shift and Impaired Neurogenesis in Down Syndrome Neural Progenitors
- (2011) Jie Lu et al. PLoS One
- Amyloid Triggers Extensive Cerebral Angiogenesis Causing Blood Brain Barrier Permeability and Hypervascularity in Alzheimer's Disease
- (2011) Kaan E. Biron et al. PLoS One
- Shedding new light on opsin evolution
- (2011) M. L. Porter et al. PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- Ca2+ sources for the exocytotic release of glutamate from astrocytes
- (2010) Vladimir Parpura et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Selective induction of astrocytic gliosis generates deficits in neuronal inhibition
- (2010) Pavel I Ortinski et al. NATURE NEUROSCIENCE
- Specific disruption of astrocytic Ca2+ signaling pathway in vivo by adeno-associated viral transduction
- (2010) Y. Xie et al. NEUROSCIENCE
- GFAPδ in radial glia and subventricular zone progenitors in the developing human cortex
- (2009) Jinte Middeldorp et al. DEVELOPMENT
- Neuronal glucose but not lactate utilization is positively correlated with NMDA-induced neurotransmission and fluctuations in cytosolic Ca2+levels
- (2009) Lasse K. Bak et al. JOURNAL OF NEUROCHEMISTRY
- Efficient Gene Delivery and Selective Transduction of Glial Cells in the Mammalian Brain by AAV Serotypes Isolated From Nonhuman Primates
- (2009) Patricia A Lawlor et al. MOLECULAR THERAPY
- Molecular Evolution of Adeno-associated Virus for Enhanced Glial Gene Delivery
- (2009) James T Koerber et al. MOLECULAR THERAPY
- Directed Evolution of a Novel Adeno-associated Virus (AAV) Vector That Crosses the Seizure-compromised Blood–Brain Barrier (BBB)
- (2009) Steven J Gray et al. MOLECULAR THERAPY
- Temporally precise in vivo control of intracellular signalling
- (2009) Raag D. Airan et al. NATURE
- GFAPpromoter elements required for region-specific and astrocyte-specific expression
- (2008) Youngjin Lee et al. GLIA
- ARG3.1/ARC expression in hippocampal dentate gyrus astrocytes: ultrastructural evidence and co-localization with glial fibrillary acidic protein
- (2008) J. J. Rodríguez et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Glutamate activates GFAP gene promoter from cultured astrocytes through TGF-1 pathways
- (2008) Luciana Ferreira Romo et al. JOURNAL OF NEUROCHEMISTRY
- Intravascular AAV9 preferentially targets neonatal neurons and adult astrocytes
- (2008) Kevin D Foust et al. NATURE BIOTECHNOLOGY
- AAV8, 9, Rh10, Rh43 Vector Gene Transfer in the Rat Brain: Effects of Serotype, Promoter and Purification Method
- (2007) Ronald L Klein et al. MOLECULAR THERAPY
- Tropism and toxicity of adeno-associated viral vector serotypes 1, 2, 5, 6, 7, 8, and 9 in rat neurons and glia in vitro
- (2007) Douglas B. Howard et al. VIROLOGY
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