The effects of trifluoperazine on brain edema, aquaporin-4 expression and metabolic markers during the acute phase of stroke using photothrombotic mouse model

Targeting Aquaporin-4 Subcellular Localization to Treat Central Nervous System Edema

(2020) Philip Kitchen et al.   CELL

Ischemia-Triggered Glutamate Excitotoxicity From the Perspective of Glial Cells

(2020) Denisa Belov Kirdajova et al.   Frontiers in Cellular Neuroscience

Tracking elemental changes in an ischemic stroke model with X-ray fluorescence imaging

(2020) M. J. Pushie et al.   Scientific Reports

Inhibitors of Mammalian Aquaporin Water Channels

(2019) Mohammed Abir-Awan et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Heart Disease and Stroke Statistics—2019 Update: A Report From the American Heart Association

(2019) Emelia J. Benjamin et al.   CIRCULATION

The energetic brain ‐ A review from students to students

(2019) M.P. Bordone et al.   JOURNAL OF NEUROCHEMISTRY

Guidelines for the Early Management of Patients With Acute Ischemic Stroke: 2019 Update to the 2018 Guidelines for the Early Management of Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association

(2019) William J. Powers et al.   STROKE

Water channel pore size determines exclusion properties but not solute selectivity

(2019) Philip Kitchen et al.   Scientific Reports

Cerebral Organoids Repair Ischemic Stroke Brain Injury

(2019) Shu-Na Wang et al.   Translational Stroke Research

Revealing the Penumbra through Imaging Elemental Markers of Cellular Metabolism in an Ischemic Stroke Model

(2018) M. Jake Pushie et al.   ACS Chemical Neuroscience

Canadian Stroke Best Practice Recommendations for Acute Stroke Management: Prehospital, Emergency Department, and Acute Inpatient Stroke Care, 6th Edition, Update 2018

(2018) JM Boulanger et al.   International Journal of Stroke

2018 Guidelines for the Early Management of Patients With Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association

(2018) William J. Powers et al.   STROKE

Modulating the water channel AQP4 alters miRNA expression, astrocyte connectivity and water diffusion in the rodent brain

(2018) Amandine Jullienne et al.   Scientific Reports

Pathophysiology and treatment of cerebral edema in traumatic brain injury

(2018) Ruchira M. Jha et al.   NEUROPHARMACOLOGY

Hypothermia increases aquaporin 4 (AQP4) plasma membrane abundance in human primary cortical astrocytes via a calcium/transient receptor potential vanilloid 4 (TRPV4)- and calmodulin-mediated mechanism

(2017) Mootaz M. Salman et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Transcriptome analysis suggests a role for the differential expression of cerebral aquaporins and the MAPK signalling pathway in human temporal lobe epilepsy

(2017) Mootaz M. Salman et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Transcriptome Analysis of Gene Expression Provides New Insights into the Effect of Mild Therapeutic Hypothermia on Primary Human Cortical Astrocytes Cultured under Hypoxia

(2017) Mootaz M. Salman et al.   Frontiers in Cellular Neuroscience

Concurrent Glycogen and Lactate Imaging with FTIR Spectroscopy To Spatially Localize Metabolic Parameters of the Glial Response Following Brain Ischemia

(2016) Mark J. Hackett et al.   ANALYTICAL CHEMISTRY

Trifluoperazine, a Well-Known Antipsychotic, Inhibits Glioblastoma Invasion by Binding to Calmodulin and Disinhibiting Calcium Release Channel IP 3 R

(2016) Seokmin Kang et al.   MOLECULAR CANCER THERAPEUTICS

A novel multi-modal platform to image molecular and elemental alterations in ischemic stroke

(2016) Sally Caine et al.   NEUROBIOLOGY OF DISEASE

Sex differences in astrocyte and microglia responses immediately following middle cerebral artery occlusion in adult mice

(2016) Helena W. Morrison et al.   NEUROSCIENCE

Cerebral Edema in Traumatic Brain Injury

(2016) Ethan A. Winkler et al.   NEUROSURGERY CLINICS OF NORTH AMERICA

Whole-Brain CT Perfusion to Quantify Acute Ischemic Penumbra and Core

(2016) Longting Lin et al.   RADIOLOGY

Evolutional Characterization of Photochemically Induced Stroke in Rats: a Multimodality Imaging and Molecular Biological Study

(2016) Nai-Wei Liu et al.   Translational Stroke Research

A New Method To Image Heme-Fe, Total Fe, and Aggregated Protein Levels after Intracerebral Hemorrhage

(2015) Mark J. Hackett et al.   ACS Chemical Neuroscience

Beyond water homeostasis: Diverse functional roles of mammalian aquaporins

(2015) Philip Kitchen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Identification and Molecular Mechanisms of the Rapid Tonicity-induced Relocalization of the Aquaporin 4 Channel

(2015) Philip Kitchen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reduced brain edema and infarct volume in aquaporin-4 deficient mice after transient focal cerebral ischemia

(2015) Xiaoming Yao et al.   NEUROSCIENCE LETTERS

Elevated Calcium after Acute Ischemic Stroke: Association with a Poor Short-Term Outcome and Long-Term Mortality

(2015) Jong-Won Chung et al.   Journal of Stroke

In Situ Biospectroscopic Investigation of Rapid Ischemic and Postmortem Induced Biochemical Alterations in the Rat Brain

(2014) Mark J. Hackett et al.   ACS Chemical Neuroscience

Elemental and Chemically Specific X-ray Fluorescence Imaging of Biological Systems

(2014) M. Jake Pushie et al.   CHEMICAL REVIEWS

Reduction of Cerebral Edema after Traumatic Brain Injury Using an Osmotic Transport Device

(2014) Devin W. McBride et al.   JOURNAL OF NEUROTRAUMA

Aquaporins: important but elusive drug targets

(2014) Alan S. Verkman et al.   NATURE REVIEWS DRUG DISCOVERY

Mechanisms of Astrocyte-Mediated Cerebral Edema

(2014) Jesse A. Stokum et al.   NEUROCHEMICAL RESEARCH

Aquaporin and brain diseases

(2013) Jérôme Badaut et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

The protective role of Tongxinluo on blood–brain barrier after ischemia–reperfusion brain injury

(2013) Ye Liu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Aquaporin water channels in the nervous system

(2013) Marios C. Papadopoulos et al.   NATURE REVIEWS NEUROSCIENCE

Photothrombotic Ischemia: A Minimally Invasive and Reproducible Photochemical Cortical Lesion Model for Mouse Stroke Studies

(2013) Vivien Labat-gest et al.   Jove-Journal of Visualized Experiments

Effect of trifluoperazine on toxicity, HIF-1α induction and hepatocyte regeneration in acetaminophen toxicity in mice

(2012) Shubhra Chaudhuri et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Chemical alterations to murine brain tissue induced by formalin fixation: implications for biospectroscopic imaging and mapping studies of disease pathogenesis

(2011) Mark J. Hackett et al.   ANALYST

Brain Lactate Metabolism: The Discoveries and the Controversies

(2011) Gerald A Dienel   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Continuous Monitoring of the Monro-Kellie Doctrine: Is It Possible?

(2011) Dong-Joo Kim et al.   JOURNAL OF NEUROTRAUMA

Glial-conditional deletion of aquaporin-4 (Aqp4) reduces blood-brain water uptake and confers barrier function on perivascular astrocyte endfeet

(2011) N. N. Haj-Yasein et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of brain aquaporins

(2010) Marina Zelenina   NEUROCHEMISTRY INTERNATIONAL

The neuroprotective mechanism of brain ischemic preconditioning

(2009) Xiao-qian Liu et al.   ACTA PHARMACOLOGICA SINICA

Cell-cell and intracellular lactate shuttles

(2009) George A. Brooks   JOURNAL OF PHYSIOLOGY-LONDON

Acute Vascular Disruption and Aquaporin 4 Loss After Stroke

(2009) Beth Friedman et al.   STROKE

Protective Role of Early Aquaporin 4 Induction against Postischemic Edema Formation

(2008) Lorenz Hirt et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

In Vivo Calcium Imaging Reveals Functional Rewiring of Single Somatosensory Neurons after Stroke

(2008) I. R. Winship et al.   JOURNAL OF NEUROSCIENCE