Cellular selectivity of AAV serotypes for gene delivery in neurons and astrocytes by neonatal intracerebroventricular injection

Systemic application of AAV vectors targeting GFAP-expressing astrocytes in Z -Q175-KI Huntington's disease mice

(2016) Tatyana Vagner et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

AAV1/2-mediated BDNF gene therapy in a transgenic rat model of Huntington’s disease

(2015) B Connor et al.   GENE THERAPY

Adeno-associated viral serotypes produce differing titers and differentially transduce neurons within the rat basal and lateral amygdala

(2014) Roopashri Holehonnur et al.   BMC NEUROSCIENCE

Overexpression of the Astrocyte Glutamate Transporter GLT1 Exacerbates Phrenic Motor Neuron Degeneration, Diaphragm Compromise, and Forelimb Motor Dysfunction following Cervical Contusion Spinal Cord Injury

(2014) K. Li et al.   JOURNAL OF NEUROSCIENCE

Advanced CLARITY for rapid and high-resolution imaging of intact tissues

(2014) Raju Tomer et al.   Nature Protocols

Widespread neuron-specific transgene expression in brain and spinal cord following synapsin promoter-driven AAV9 neonatal intracerebroventricular injection

(2014) Jesse R. McLean et al.   NEUROSCIENCE LETTERS

Chronic Treatment with Novel Small Molecule Hsp90 Inhibitors Rescues Striatal Dopamine Levels but Not α-Synuclein-Induced Neuronal Cell Loss

(2014) Nikolaus R. McFarland et al.   PLoS One

Viral transduction of the neonatal brain delivers controllable genetic mosaicism for visualising and manipulating neuronal circuitsin vivo

(2013) Ji-Yoen Kim et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Safety/feasibility of targeting the substantia nigra with AAV2-neurturin in Parkinson patients

(2013) R. T. Bartus et al.   NEUROLOGY

Capsid Serotype and Timing of Injection Determines AAV Transduction in the Neonatal Mice Brain

(2013) Paramita Chakrabarty et al.   PLoS One

Glial Promoter Selectivity following AAV-Delivery to the Immature Brain

(2013) Georg von Jonquieres et al.   PLoS One

Analysis of Transduction Efficiency, Tropism and Axonal Transport of AAV Serotypes 1, 2, 5, 6, 8 and 9 in the Mouse Brain

(2013) Dominik F. Aschauer et al.   PLoS One

Efficient gene delivery and selective transduction of astrocytes in the mammalian brain using viral vectors

(2013) Nicolas Merienne et al.   Frontiers in Cellular Neuroscience

Long-Term Evaluation of a Phase 1 Study of AADC Gene Therapy for Parkinson's Disease

(2012) Gabriele Mittermeyer et al.   HUMAN GENE THERAPY

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

AAV serotype 2/1-mediated gene delivery of anti-inflammatory interleukin-10 enhances neurogenesis and cognitive function in APP+PS1 mice

(2011) T Kiyota et al.   GENE THERAPY

Preclinical Differences of Intravascular AAV9 Delivery to Neurons and Glia: A Comparative Study of Adult Mice and Nonhuman Primates

(2011) Steven J Gray et al.   MOLECULAR THERAPY

Efficient Gene Therapy for Parkinson's Disease Using Astrocytes as Hosts for Localized Neurotrophic Factor Delivery

(2011) Anja Drinkut et al.   MOLECULAR THERAPY

1,3-Dinitrobenzene–Induced Metabolic Impairment through Selective Inactivation of the Pyruvate Dehydrogenase Complex

(2011) James A. Miller et al.   TOXICOLOGICAL SCIENCES

Gene delivery of AAV2-neurturin for Parkinson's disease: a double-blind, randomised, controlled trial

(2010) William J Marks et al.   LANCET NEUROLOGY

Comparison of transduction efficiency of recombinant AAV serotypes 1, 2, 5, and 8 in the rat nigrostriatal system

(2009) Nikolaus R. McFarland et al.   JOURNAL OF NEUROCHEMISTRY

Efficient Gene Delivery and Selective Transduction of Glial Cells in the Mammalian Brain by AAV Serotypes Isolated From Nonhuman Primates

(2009) Patricia A Lawlor et al.   MOLECULAR THERAPY

AAV1/2-mediated CNS Gene Delivery of Dominant-negative CCL2 Mutant Suppresses Gliosis, β-amyloidosis, and Learning Impairment of APP/PS1 Mice

(2009) Tomomi Kiyota et al.   MOLECULAR THERAPY

Gene Therapy Using Adeno-Associated Virus Vectors

(2008) S. Daya et al.   CLINICAL MICROBIOLOGY REVIEWS

GFAPpromoter elements required for region-specific and astrocyte-specific expression

(2008) Youngjin Lee et al.   GLIA

Intravascular AAV9 preferentially targets neonatal neurons and adult astrocytes

(2008) Kevin D Foust et al.   NATURE BIOTECHNOLOGY

Specific AAV serotypes stably transduce primary hippocampal and cortical cultures with high efficiency and low toxicity

(2007) Nicolas C. Royo et al.   BRAIN RESEARCH

Tropism and toxicity of adeno-associated viral vector serotypes 1, 2, 5, 6, 7, 8, and 9 in rat neurons and glia in vitro

(2007) Douglas B. Howard et al.   VIROLOGY