标题
Higher-order organization of biomolecular condensates
作者
关键词
-
出版物
Open Biology
Volume 11, Issue 6, Pages 210137
出版商
The Royal Society
发表日期
2021-06-16
DOI
10.1098/rsob.210137
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- p53 is a central regulator driving neurodegeneration caused by C9orf72 poly(PR)
- (2021) Maya Maor-Nof et al. CELL
- ZSP‐1 is a Z granule surface protein required for Z granule fluidity and germline immortality in Caenorhabditis elegans
- (2021) Gang Wan et al. EMBO JOURNAL
- FUS and TDP-43 Phases in Health and Disease
- (2021) Bede Portz et al. TRENDS IN BIOCHEMICAL SCIENCES
- p62/SQSTM1-droplet serves as a platform for autophagosome formation and anti-oxidative stress response
- (2021) Shun Kageyama et al. Nature Communications
- Self‐assembly of multi‐component mitochondrial nucleoids via phase separation
- (2021) Marina Feric et al. EMBO JOURNAL
- Open Access: A Role for p53 in c9ALS/FTD?
- (2021) Charlotte M. Fare et al. TRENDS IN GENETICS
- Sequence-encoded and composition-dependent protein-RNA interactions control multiphasic condensate morphologies
- (2021) Taranpreet Kaur et al. Nature Communications
- In vivo reconstitution finds multivalent RNA-RNA interactions as drivers of mesh-like condensates
- (2021) Weirui Ma et al. eLife
- Combating deleterious phase transitions in neurodegenerative disease
- (2021) April L. Darling et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- The role of liquid–liquid phase separation in regulating enzyme activity
- (2021) Brian G. O'Flynn et al. CURRENT OPINION IN CELL BIOLOGY
- (Dis)Solving the problem of aberrant protein states
- (2021) Charlotte M. Fare et al. Disease Models & Mechanisms
- p53 mediates target gene association with nuclear speckles for amplified RNA expression
- (2021) Katherine A. Alexander et al. MOLECULAR CELL
- RNA Droplets
- (2020) Kevin Rhine et al. Annual Review of Biophysics
- Physical Principles Underlying the Complex Biology of Intracellular Phase Transitions
- (2020) Jeong-Mo Choi et al. Annual Review of Biophysics
- Liquid-Liquid Phase Separation of Histone Proteins in Cells: Role in Chromatin Organization
- (2020) Anisha Shakya et al. BIOPHYSICAL JOURNAL
- Modulation of RNA Condensation by the DEAD-Box Protein eIF4A
- (2020) Devin Tauber et al. CELL
- UBAP2L Forms Distinct Cores that Act in Nucleating Stress Granules Upstream of G3BP1
- (2020) Luca Cirillo et al. CURRENT BIOLOGY
- Regulated changes in material properties underlie centrosome disassembly during mitotic exit
- (2020) Matthäus Mittasch et al. JOURNAL OF CELL BIOLOGY
- Mouse Heterochromatin Adopts Digital Compaction States without Showing Hallmarks of HP1-Driven Liquid-Liquid Phase Separation
- (2020) Fabian Erdel et al. MOLECULAR CELL
- Proteome-wide observation of the phenomenon of life on the edge of solubility
- (2020) Giulia Vecchi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Valence and patterning of aromatic residues determine the phase behavior of prion-like domains
- (2020) Erik W. Martin et al. SCIENCE
- C9orf72 arginine-rich dipeptide repeat proteins disrupt karyopherin-mediated nuclear import
- (2020) Lindsey R Hayes et al. eLife
- Competing Protein-RNA Interaction Networks Control Multiphase Intracellular Organization
- (2020) David W. Sanders et al. CELL
- G3BP1 Is a Tunable Switch that Triggers Phase Separation to Assemble Stress Granules
- (2020) Peiguo Yang et al. CELL
- RNA-Induced Conformational Switching and Clustering of G3BP Drive Stress Granule Assembly by Condensation
- (2020) Jordina Guillén-Boixet et al. CELL
- Just Took a DNA Test, Turns Out 100% Not That Phase
- (2020) Aaron D. Gitler et al. MOLECULAR CELL
- Phase separation directs ubiquitination of gene-body nucleosomes
- (2020) Laura D. Gallego et al. NATURE
- Composition-dependent thermodynamics of intracellular phase separation
- (2020) Joshua A. Riback et al. NATURE
- Liquid network connectivity regulates the stability and composition of biomolecular condensates with many components
- (2020) Jorge R. Espinosa et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Liquid-liquid phase separation drives skin barrier formation
- (2020) Felipe Garcia Quiroz et al. SCIENCE
- Phase transition of RNA−protein complexes into ordered hollow condensates
- (2020) Ibraheem Alshareedah et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Nucleated transcriptional condensates amplify gene expression
- (2020) Ming-Tzo Wei et al. NATURE CELL BIOLOGY
- Mitochondrial RNA granules are fluid condensates positioned by membrane dynamics
- (2020) Timo Rey et al. NATURE CELL BIOLOGY
- C9orf72 poly(GR) aggregation induces TDP-43 proteinopathy
- (2020) Casey N. Cook et al. Science Translational Medicine
- Tunable multiphase dynamics of arginine and lysine liquid condensates
- (2020) Rachel S. Fisher et al. Nature Communications
- Condensed Chromatin Behaves like a Solid on the Mesoscale In Vitro and in Living Cells
- (2020) Hilmar Strickfaden et al. CELL
- Phase Separation as a Missing Mechanism for Interpretation of Disease Mutations
- (2020) Brian Tsang et al. CELL
- Biochemical Timekeeping Via Reentrant Phase Transitions
- (2020) Bede Portz et al. JOURNAL OF MOLECULAR BIOLOGY
- Protein condensates as aging Maxwell fluids
- (2020) Louise Jawerth et al. SCIENCE
- Nuclear Import Receptors Directly Bind to Arginine-Rich Dipeptide Repeat Proteins and Suppress Their Pathological Interactions
- (2020) Saskia Hutten et al. Cell Reports
- Multicolour single-molecule tracking of mRNA interactions with RNP granules
- (2019) Stephanie L. Moon et al. NATURE CELL BIOLOGY
- Aberrant Phase Transitions: Side Effects and Novel Therapeutic Strategies in Human Disease
- (2019) Veronica Verdile et al. Frontiers in Genetics
- Template-directed RNA polymerization and enhanced ribozyme catalysis inside membraneless compartments formed by coacervates
- (2019) Raghav R. Poudyal et al. Nature Communications
- Heterochromatin anomalies and double-stranded RNA accumulation underlie C9orf72 poly(PR) toxicity
- (2019) Yong-Jie Zhang et al. SCIENCE
- Stoichiometry controls activity of phase-separated clusters of actin signaling proteins
- (2019) Lindsay B. Case et al. SCIENCE
- RNA Binding Antagonizes Neurotoxic Phase Transitions of TDP-43
- (2019) Jacob R. Mann et al. NEURON
- A gel phase promotes condensation of liquid P granules in Caenorhabditis elegans embryos
- (2019) Andrea Putnam et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Considerations and Challenges in Studying Liquid-Liquid Phase Separation and Biomolecular Condensates
- (2019) Simon Alberti et al. CELL
- Pollen Cell Wall Patterns Form from Modulated Phases
- (2019) Asja Radja et al. CELL
- Dynamic Recruitment of Single RNAs to Processing Bodies Depends on RNA Functionality
- (2019) Sethuramasundaram Pitchiaya et al. MOLECULAR CELL
- Spontaneous driving forces give rise to protein−RNA condensates with coexisting phases and complex material properties
- (2019) Steven Boeynaems et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Chronic optogenetic induction of stress granules is cytotoxic and reveals the evolution of ALS-FTD pathology
- (2019) Peipei Zhang et al. eLife
- Histone Modifications Regulate Chromatin Compartmentalization by Contributing to a Phase Separation Mechanism
- (2019) Liang Wang et al. MOLECULAR CELL
- DEAD-box ATPases are global regulators of phase-separated organelles
- (2019) Maria Hondele et al. NATURE
- Phospho-dependent phase separation of FMRP and CAPRIN1 recapitulates regulation of translation and deadenylation
- (2019) Tae Hun Kim et al. SCIENCE
- RRM adjacent TARDBP mutations disrupt RNA binding and enhance TDP-43 proteinopathy
- (2019) Han-Jou Chen et al. BRAIN
- Organization of Chromatin by Intrinsic and Regulated Phase Separation
- (2019) Bryan A. Gibson et al. CELL
- Nucleo-cytoplasmic Partitioning of ARF Proteins Controls Auxin Responses in Arabidopsis thaliana
- (2019) Samantha K. Powers et al. MOLECULAR CELL
- Properties of Stress Granule and P-Body Proteomes
- (2019) Ji-Young Youn et al. MOLECULAR CELL
- HP1 reshapes nucleosome core to promote phase separation of heterochromatin
- (2019) S. Sanulli et al. NATURE
- Stress granules and neurodegeneration
- (2019) Benjamin Wolozin et al. NATURE REVIEWS NEUROSCIENCE
- Cytoplasmic DAXX drives SQSTM1/p62 phase condensation to activate Nrf2-mediated stress response
- (2019) Yi Yang et al. Nature Communications
- LASSI: A lattice model for simulating phase transitions of multivalent proteins
- (2019) Jeong-Mo Choi et al. PLoS Computational Biology
- Nucleolar dynamics and interactions with nucleoplasm in living cells
- (2019) Christina M Caragine et al. eLife
- P-Bodies: Composition, Properties, and Functions
- (2018) Yang Luo et al. BIOCHEMISTRY
- Surface Properties Determining Passage Rates of Proteins through Nuclear Pores
- (2018) Steffen Frey et al. CELL
- Context-Dependent and Disease-Specific Diversity in Protein Interactions within Stress Granules
- (2018) Sebastian Markmiller et al. CELL
- A Molecular Grammar Governing the Driving Forces for Phase Separation of Prion-like RNA Binding Proteins
- (2018) Jie Wang et al. CELL
- Nuclear-Import Receptors Reverse Aberrant Phase Transitions of RNA-Binding Proteins with Prion-like Domains
- (2018) Lin Guo et al. CELL
- Reversible induction of TDP-43 granules in cortical neurons after traumatic injury
- (2018) Diana Wiesner et al. EXPERIMENTAL NEUROLOGY
- Single-molecule imaging reveals dynamic biphasic partition of RNA-binding proteins in stress granules
- (2018) Benedikt Niewidok et al. JOURNAL OF CELL BIOLOGY
- Amyloid assembly and disassembly
- (2018) Edward Chuang et al. JOURNAL OF CELL SCIENCE
- ZNFX-1 Functions within Perinuclear Nuage to Balance Epigenetic Signals
- (2018) Takao Ishidate et al. MOLECULAR CELL
- Controlling compartmentalization by non-membrane-bound organelles
- (2018) Richard J. Wheeler et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- Physical principles of intracellular organization via active and passive phase transitions
- (2018) Joel Berry et al. REPORTS ON PROGRESS IN PHYSICS
- RNA buffers the phase separation behavior of prion-like RNA binding proteins
- (2018) Shovamayee Maharana et al. SCIENCE
- DNA-induced liquid phase condensation of cGAS activates innate immune signaling
- (2018) Mingjian Du et al. SCIENCE
- Phase separation of a yeast prion protein promotes cellular fitness
- (2018) Titus M. Franzmann et al. SCIENCE
- Organization and Function of Non-dynamic Biomolecular Condensates
- (2018) Jeffrey B. Woodruff et al. TRENDS IN BIOCHEMICAL SCIENCES
- Protein Phase Separation: A New Phase in Cell Biology
- (2018) Steven Boeynaems et al. TRENDS IN CELL BIOLOGY
- Self-interaction of NPM1 modulates multiple mechanisms of liquid–liquid phase separation
- (2018) Diana M. Mitrea et al. Nature Communications
- A compartmentalized signaling network mediates crossover control in meiosis
- (2018) Liangyu Zhang et al. eLife
- Pi-Pi contacts are an overlooked protein feature relevant to phase separation
- (2018) Robert McCoy Vernon et al. eLife
- A New Lens for RNA Localization: Liquid-Liquid Phase Separation
- (2018) Erin M. Langdon et al. Annual Review of Microbiology
- The molecular language of membraneless organelles
- (2018) Edward Gomes et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Who's In and Who's Out—Compositional Control of Biomolecular Condensates
- (2018) Jonathon A. Ditlev et al. JOURNAL OF MOLECULAR BIOLOGY
- Cancer Mutations of the Tumor Suppressor SPOP Disrupt the Formation of Active, Phase-Separated Compartments
- (2018) Jill J. Bouchard et al. MOLECULAR CELL
- Poly(ADP-Ribose) Prevents Pathological Phase Separation of TDP-43 by Promoting Liquid Demixing and Stress Granule Localization
- (2018) Leeanne McGurk et al. MOLECULAR CELL
- Spatiotemporal regulation of liquid-like condensates in epigenetic inheritance
- (2018) Gang Wan et al. NATURE
- Phase transitioned nuclear Oskar promotes cell division of Drosophila primordial germ cells
- (2018) Kathryn E Kistler et al. eLife
- Ubiquitin Regulation: The Histone Modifying Enzyme′s Story
- (2018) Jianlin Wang et al. Cells
- Differences between acute and chronic stress granules, and how these differences may impact function in human disease
- (2018) Lucas C. Reineke et al. BIOCHEMICAL PHARMACOLOGY
- A Membraneless Organelle Associated with the Endoplasmic Reticulum Enables 3′UTR-Mediated Protein-Protein Interactions
- (2018) Weirui Ma et al. CELL
- Mapping Local and Global Liquid Phase Behavior in Living Cells Using Photo-Oligomerizable Seeds
- (2018) Dan Bracha et al. CELL
- 3′ UTRs in the Eye of the TIGER
- (2018) Bede Portz et al. DEVELOPMENTAL CELL
- Remodeling of the endoplasmic reticulum in Caenorhabditis elegans oocytes is regulated by CGH-1
- (2018) Shaughna Langerak et al. GENESIS
- TDP-43 and RNA form amyloid-like myo-granules in regenerating muscle
- (2018) Thomas O. Vogler et al. NATURE
- Membraneless nuclear organelles and the search for phases within phases
- (2018) Iain A. Sawyer et al. Wiley Interdisciplinary Reviews-RNA
- P-Body Purification Reveals the Condensation of Repressed mRNA Regulons
- (2017) Arnaud Hubstenberger et al. MOLECULAR CELL
- Biomolecular condensates: organizers of cellular biochemistry
- (2017) Salman F. Banani et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Eye patches: Protein assembly of index-gradient squid lenses
- (2017) J. Cai et al. SCIENCE
- The synaptonemal complex has liquid crystalline properties and spatially regulates meiotic recombination factors
- (2017) Ofer Rog et al. eLife
- A de novo 10p11.23-p12.1 deletion recapitulates the phenotype observed inWACmutations and strengthens the role ofWACin intellectual disability and behavior disorders
- (2016) Fatma Abdelhedi et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- Architectural RNAs (arcRNAs): A class of long noncoding RNAs that function as the scaffold of nuclear bodies
- (2016) Takeshi Chujo et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- Prion-like domains as epigenetic regulators, scaffolds for subcellular organization, and drivers of neurodegenerative disease
- (2016) Zachary M. March et al. BRAIN RESEARCH
- Amyloid-like Self-Assembly of a Cellular Compartment
- (2016) Elvan Boke et al. CELL
- ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure
- (2016) Saumya Jain et al. CELL
- Compositional Control of Phase-Separated Cellular Bodies
- (2016) Salman F. Banani et al. CELL
- Coexisting Liquid Phases Underlie Nucleolar Subcompartments
- (2016) Marina Feric et al. CELL
- Phase separation in biology; functional organization of a higher order
- (2016) Diana M. Mitrea et al. Cell Communication and Signaling
- A glass menagerie of low complexity sequences
- (2016) Randal Halfmann CURRENT OPINION IN STRUCTURAL BIOLOGY
- Higher‐order oligomerization promotes localization of SPOP to liquid nuclear speckles
- (2016) Melissa R Marzahn et al. EMBO JOURNAL
- Structural, super-resolution microscopy analysis of paraspeckle nuclear body organization
- (2016) Jason A. West et al. JOURNAL OF CELL BIOLOGY
- Phasing in and out
- (2016) James Shorter Nature Chemistry
- Membraneless organelles can melt nucleic acid duplexes and act as biomolecular filters
- (2016) Timothy J. Nott et al. Nature Chemistry
- Structural mechanism for the recognition and ubiquitination of a single nucleosome residue by Rad6–Bre1
- (2016) Laura D. Gallego et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Phase separation of signaling molecules promotes T cell receptor signal transduction
- (2016) Xiaolei Su et al. SCIENCE
- Principles and Properties of Stress Granules
- (2016) David S.W. Protter et al. TRENDS IN CELL BIOLOGY
- In Vivo Formation of Vacuolated Multi-phase Compartments Lacking Membranes
- (2016) Hermann Broder Schmidt et al. Cell Reports
- Spatial patterning of P granules by RNA-induced phase separation of the intrinsically-disordered protein MEG-3
- (2016) Jarrett Smith et al. eLife
- Distinct stages in stress granule assembly and disassembly
- (2016) Joshua R Wheeler et al. eLife
- Phase Separation by Low Complexity Domains Promotes Stress Granule Assembly and Drives Pathological Fibrillization
- (2015) Amandine Molliex et al. CELL
- A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation
- (2015) Avinash Patel et al. CELL
- WACloss-of-function mutations cause a recognisable syndrome characterised by dysmorphic features, developmental delay and hypotonia and recapitulate 10p11.23 microdeletion syndrome
- (2015) Cori DeSanto et al. JOURNAL OF MEDICAL GENETICS
- An acetylation switch controls TDP-43 function and aggregation propensity
- (2015) Todd J. Cohen et al. Nature Communications
- The Selective Autophagy Receptor p62 Forms a Flexible Filamentous Helical Scaffold
- (2015) Rodolfo Ciuffa et al. Cell Reports
- The Nucleosome Acidic Patch Regulates the H2B K123 Monoubiquitylation Cascade and Transcription Elongation in Saccharomyces cerevisiae
- (2015) Christine E. Cucinotta et al. PLoS Genetics
- Liquid-Liquid Phase Separation in Biology
- (2014) Anthony A. Hyman et al. Annual Review of Cell and Developmental Biology
- Transgenerational Epigenetic Inheritance: Myths and Mechanisms
- (2014) Edith Heard et al. CELL
- The quantified cell
- (2014) Avi Flamholz et al. MOLECULAR BIOLOGY OF THE CELL
- The metazoan protein disaggregase and amyloid depolymerase system
- (2014) Mariana P Torrente et al. Prion
- Bidirectional transcripts of the expanded C9orf72 hexanucleotide repeat are translated into aggregating dipeptide repeat proteins
- (2013) Kohji Mori et al. ACTA NEUROPATHOLOGICA
- GRSF1 Regulates RNA Processing in Mitochondrial RNA Granules
- (2013) Alexis A. Jourdain et al. Cell Metabolism
- Translation Repressors, an RNA Helicase, and Developmental Cues Control RNP Phase Transitions during Early Development
- (2013) Arnaud Hubstenberger et al. DEVELOPMENTAL CELL
- Stress granules as crucibles of ALS pathogenesis
- (2013) Yun R. Li et al. JOURNAL OF CELL BIOLOGY
- Predicting phase behavior in multicomponent mixtures
- (2013) William M. Jacobs et al. JOURNAL OF CHEMICAL PHYSICS
- Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS
- (2013) Hong Joo Kim et al. NATURE
- Paraspeckle formation during the biogenesis of long non-coding RNAs
- (2013) Takao Naganuma et al. RNA Biology
- Bridging the transgenerational gap with epigenetic memory
- (2013) Jana P. Lim et al. TRENDS IN GENETICS
- The tip of the iceberg: RNA-binding proteins with prion-like domains in neurodegenerative disease
- (2012) Oliver D. King et al. BRAIN RESEARCH
- The Dual Organization of P-bodies Revealed by Immunoelectron Microscopy and Electron Tomography
- (2012) Nicolas Cougot et al. JOURNAL OF MOLECULAR BIOLOGY
- Transient Sequestration of TORC1 into Stress Granules during Heat Stress
- (2012) Terunao Takahara et al. MOLECULAR CELL
- Phase transitions in the assembly of multivalent signalling proteins
- (2012) Pilong Li et al. NATURE
- A nuclear Argonaute promotes multigenerational epigenetic inheritance and germline immortality
- (2012) Bethany A. Buckley et al. NATURE
- RNA catalysis through compartmentalization
- (2012) Christopher A. Strulson et al. Nature Chemistry
- Small Heat Shock Proteins Potentiate Amyloid Dissolution by Protein Disaggregases from Yeast and Humans
- (2012) Martin L. Duennwald et al. PLOS BIOLOGY
- Patchy colloids: state of the art and perspectives
- (2011) Emanuela Bianchi et al. PHYSICAL CHEMISTRY CHEMICAL PHYSICS
- The Mammalian Disaggregase Machinery: Hsp110 Synergizes with Hsp70 and Hsp40 to Catalyze Protein Disaggregation and Reactivation in a Cell-Free System
- (2011) James Shorter PLoS One
- Prion-like disorders: blurring the divide between transmissibility and infectivity
- (2010) M. Cushman et al. JOURNAL OF CELL SCIENCE
- In vivo kinetics of U4/U6·U5 tri-snRNP formation in Cajal bodies
- (2010) Ivan Novotný et al. MOLECULAR BIOLOGY OF THE CELL
- The Nucleolus under Stress
- (2010) Séverine Boulon et al. MOLECULAR CELL
- A simple approach to polymer mixture miscibility
- (2010) J. S. Higgins et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES
- RAD6-Mediated Transcription-Coupled H2B Ubiquitylation Directly Stimulates H3K4 Methylation in Human Cells
- (2009) Jaehoon Kim et al. CELL
- Unravelling the ultrastructure of stress granules and associated P-bodies in human cells
- (2009) S. Souquere et al. JOURNAL OF CELL SCIENCE
- Eukaryotic Stress Granules: The Ins and Outs of Translation
- (2009) J. Ross Buchan et al. MOLECULAR CELL
- Germline P Granules Are Liquid Droplets That Localize by Controlled Dissolution/Condensation
- (2009) C. P. Brangwynne et al. SCIENCE
- Transmission Dynamics of Heritable Silencing Induced by Double-Stranded RNA in Caenorhabditis elegans
- (2008) Rosa M. Alcazar et al. GENETICS
- H2B Ubiquitylation Plays a Role in Nucleosome Dynamics during Transcription Elongation
- (2008) Alastair B. Fleming et al. MOLECULAR CELL
- Formation of stress granules inhibits apoptosis by suppressing stress-responsive MAPK pathways
- (2008) Kyoko Arimoto et al. NATURE CELL BIOLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started