Estrogen-related receptor alpha (ERRα) is a key regulator of intestinal homeostasis and protects against colitis

Estrogen-Related Receptor Alpha: An Under-Appreciated Potential Target for the Treatment of Metabolic Diseases

(2020) Madhulika Tripathi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Structural weakening of the colonic mucus barrier is an early event in ulcerative colitis pathogenesis

(2019) Sjoerd van der Post et al.   GUT

Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases

(2019) Jason Lloyd-Price et al.   NATURE

New insights into the interplay between autophagy, gut microbiota and inflammatory responses in IBD

(2019) Anaïs Larabi et al.   Autophagy

Serological Assessment of the Quality of Wound Healing Processes in Crohn’s Disease

(2019) Shu Sun et al.   Journal of Gastrointestinal and Liver Diseases

Microbial genes and pathways in inflammatory bowel disease

(2019) Melanie Schirmer et al.   NATURE REVIEWS MICROBIOLOGY

Dipotassium Glycyrrhizate Improves Intestinal Mucosal Healing by Modulating Extracellular Matrix Remodeling Genes and Restoring Epithelial Barrier Functions

(2019) Laura Stronati et al.   Frontiers in Immunology

Nuclear Receptors Regulate Intestinal Inflammation in the Context of IBD

(2019) Victoria Klepsch et al.   Frontiers in Immunology

Mitochondrial DNA Is a Pro-Inflammatory Damage-Associated Molecular Pattern Released During Active IBD

(2018) Ray K Boyapati et al.   INFLAMMATORY BOWEL DISEASES

Mitochondrial function — gatekeeper of intestinal epithelial cell homeostasis

(2018) Eva Rath et al.   Nature Reviews Gastroenterology & Hepatology

Thyroid hormone receptor and ERRα coordinately regulate mitochondrial fission, mitophagy, biogenesis, and function

(2018) Brijesh K. Singh et al.   Science Signaling

High expression of estrogen-related receptor α is significantly associated with poor prognosis in patients with colorectal cancer

(2018) Rong Liang et al.   Oncology Letters

Thyroid hormone receptor and ERRα coordinately regulate mitochondrial fission, mitophagy, biogenesis, and function

(2018) Brijesh K. Singh et al.   Science Signaling

Mitochondria in innate immune signaling

(2018) Balaji Banoth et al.   Translational Research

Deletion of Stearoyl-CoA Desaturase-1 From the Intestinal Epithelium Promotes Inflammation and Tumorigenesis, Reversed by Dietary Oleate

(2018) Simon Ducheix et al.   GASTROENTEROLOGY

Ulcerative colitis mucosal transcriptomes reveal mitochondriopathy and personalized mechanisms underlying disease severity and treatment response

(2018) Yael Haberman et al.   Nature Communications

Microbiota-activated PPAR-γ signaling inhibits dysbiotic Enterobacteriaceae expansion

(2017) Mariana X. Byndloss et al.   SCIENCE

Mitochondrial ATP Depletion Disrupts Caco-2 Monolayer Integrity and Internalizes Claudin 7

(2017) Lonneke M. JanssenDuijghuijsen et al.   Frontiers in Physiology

Nitric oxide as a potential biomarker in inflammatory bowel disease

(2017) Nesina Avdagić et al.   Bosnian Journal of Basic Medical Sciences

Peroxisome Proliferator-activated Receptor-γ Coactivator 1-α (PGC1α) Protects against Experimental Murine Colitis

(2016) Kellie E. Cunningham et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

There and back again: The journey of the estrogen-related receptors in the cancer realm

(2016) Ingrid S. Tam et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

ERRα mediates metabolic adaptations driving lapatinib resistance in breast cancer

(2016) Geneviève Deblois et al.   Nature Communications

Constitutive activities of estrogen-related receptors: Transcriptional regulation of metabolism by the ERR pathways in health and disease

(2015) Janice M. Huss et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Mitochondrial quality control pathways as determinants of metabolic health

(2015) Ntsiki M. Held et al.   BIOESSAYS

Orphan Nuclear Receptor ERRα Controls Macrophage Metabolic Signaling and A20 Expression to Negatively Regulate TLR-Induced Inflammation

(2015) Jae-Min Yuk et al.   IMMUNITY

The multiple universes of estrogen-related receptor α and γ in metabolic control and related diseases

(2014) Étienne Audet-walsh et al.   ACTA PHARMACOLOGICA SINICA

Pediatric Crohn disease patients exhibit specific ileal transcriptome and microbiome signature

(2014) Yael Haberman et al.   JOURNAL OF CLINICAL INVESTIGATION

Molecular and Genetic Crosstalks between mTOR and ERRα Are Key Determinants of Rapamycin-Induced Nonalcoholic Fatty Liver

(2013) Cédric Chaveroux et al.   Cell Metabolism

Apolipoprotein A1 potentiates lipoxin A4 synthesis and recovery of allergen-induced disrupted tight junctions in the airway epithelium

(2013) S.-W. Park et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Loss of estrogen-related receptor   promotes hepatocarcinogenesis development via metabolic and inflammatory disturbances

(2013) E.-J. Hong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CC Chemokine Ligand 20 and Its Cognate Receptor CCR6 in Mucosal T Cell Immunology and Inflammatory Bowel Disease: Odd Couple or Axis of Evil?

(2013) Adrian Y. S. Lee et al.   Frontiers in Immunology

Antioxidative properties of paraoxonase 2 in intestinal epithelial cells

(2012) Louis-Philippe Précourt et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

PGC-1β regulates mouse carnitine–acylcarnitine translocase through estrogen-related receptor α

(2012) Mar Gacias et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mitochondrial electron transport chain complex dysfunction in the colonic mucosa in ulcerative colitis

(2012) Srikanth Santhanam et al.   INFLAMMATORY BOWEL DISEASES

Quantification of low expressed SCD1 gene in colonic mucosa from patients with active ulcerative colitis

(2011) Nallely Bueno-Hernández et al.   INFLAMMATORY BOWEL DISEASES

Identification of Diaryl Ether-Based Ligands for Estrogen-Related Receptor α as Potential Antidiabetic Agents

(2011) Raymond J. Patch et al.   JOURNAL OF MEDICINAL CHEMISTRY

Estrogen related receptors (ERRs): A new dawn in transcriptional control of mitochondrial gene networks

(2011) Lillian J. Eichner et al.   MITOCHONDRION

The IκB kinase complex regulates the stability of cytokine-encoding mRNA induced by TLR–IL-1R by controlling degradation of regnase-1

(2011) Hidenori Iwasaki et al.   NATURE IMMUNOLOGY

Peroxisome proliferator-activated receptor-  coactivator 1-  (PGC1 ) is a metabolic regulator of intestinal epithelial cell fate

(2011) I. D'Errico et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genomic Convergence among ERRα, PROX1, and BMAL1 in the Control of Metabolic Clock Outputs

(2011) Catherine R. Dufour et al.   PLoS Genetics

Characterization of intestinal gene expression profiles in Crohnʼs disease by genome-wide microarray analysis

(2010) Colin L. Noble et al.   INFLAMMATORY BOWEL DISEASES

Mitochondrial respiratory chain in the colonic mucosal of patients with ulcerative colitis

(2010) Karla G. Sifroni et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Transcriptional Control of Energy Homeostasis by the Estrogen-Related Receptors

(2008) Vincent Giguère   ENDOCRINE REVIEWS

Rosiglitazone for Active Ulcerative Colitis: A Randomized Placebo-Controlled Trial

(2008) James D. Lewis et al.   GASTROENTEROLOGY

Hepatocyte nuclear factor 4α in the intestinal epithelial cells protects against inflammatory bowel disease

(2008) Sung-Hoon Ahn et al.   INFLAMMATORY BOWEL DISEASES

Paraoxonase-1 status in Crohnʼs disease and ulcerative colitis

(2008) Dorota Boehm et al.   INFLAMMATORY BOWEL DISEASES

Signature biomarkers in Crohn's disease: toward a molecular classification

(2008) R Arsenescu et al.   Mucosal Immunology