Systems‐level approaches for understanding and engineering of the oleaginous cell factory Yarrowia lipolytica
出版年份 2021 全文链接
标题
Systems‐level approaches for understanding and engineering of the oleaginous cell factory
Yarrowia lipolytica
作者
关键词
-
出版物
BIOTECHNOLOGY AND BIOENGINEERING
Volume 118, Issue 10, Pages 3640-3654
出版商
Wiley
发表日期
2021-06-15
DOI
10.1002/bit.27859
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Development of a CRISPR/Cas9-mediated homology-independent tool for targeted genome integration in Yarrowia lipolytica
- (2021) Zhiyong Cui et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- Recent advances in systems and synthetic biology approaches for developing novel cell-factories in non-conventional yeasts
- (2021) Pradipta Patra et al. BIOTECHNOLOGY ADVANCES
- Omics-Driven Biotechnology for Industrial Applications
- (2021) Bashar Amer et al. Frontiers in Bioengineering and Biotechnology
- Comparison and Analysis of Published Genome-scale Metabolic Models of Yarrowia lipolytica
- (2020) Yu Xu et al. BIOTECHNOLOGY AND BIOPROCESS ENGINEERING
- Guide RNA Engineering Enables Dual Purpose CRISPR-Cpf1 for Simultaneous Gene Editing and Gene Regulation in Yarrowia lipolytica
- (2020) Adithya Ramesh et al. ACS Synthetic Biology
- Genetic and bioprocess engineering to improve squalene production in Yarrowia lipolytica
- (2020) Huan Liu et al. BIORESOURCE TECHNOLOGY
- High production of triterpenoids in Yarrowia lipolytica through manipulation of lipid components
- (2020) Jin-Lai Zhang et al. Biotechnology for Biofuels
- Metabolic engineering of Yarrowia lipolytica for heterologous oleanolic acid production
- (2020) Dashuai Li et al. CHEMICAL ENGINEERING SCIENCE
- An artificial chromosome ylAC enables efficient assembly of multiple genes in Yarrowia lipolytica for biomanufacturing
- (2020) Zhong-peng Guo et al. Communications Biology
- Building kinetic models for metabolic engineering
- (2020) Charles J Foster et al. CURRENT OPINION IN BIOTECHNOLOGY
- SelProm: A Queryable and Predictive Expression Vector Selection Tool for Escherichia coli
- (2019) Adrian J. Jervis et al. ACS Synthetic Biology
- Transomics data-driven, ensemble kinetic modeling for system-level understanding and engineering of the cyanobacteria central metabolism
- (2019) Hiroki Nishiguchi et al. METABOLIC ENGINEERING
- Cellular and metabolic engineering of oleaginous yeast Yarrowia lipolytica for bioconversion of hydrophobic substrates into high-value products
- (2019) Ya-Hue Valerie Soong et al. ENGINEERING IN LIFE SCIENCES
- CRISPR-mediated genome editing in non-conventional yeasts for biotechnological applications
- (2019) Peng Cai et al. Microbial Cell Factories
- High production of fatty alcohols in Yarrowia lipolytica by coordination with glycolysis
- (2019) Jin-Lai Zhang et al. Science China-Chemistry
- Screening Various Yarrowia lipolytica Strains for Citric Acid Production
- (2019) Erdem Carsanba et al. YEAST
- In silico identification of metabolic engineering strategies for improved lipid production in Yarrowia lipolytica by genome-scale metabolic modeling
- (2019) Minsuk Kim et al. Biotechnology for Biofuels
- 800-kyr land temperature variations modulated by vegetation changes on Chinese Loess Plateau
- (2019) Hongxuan Lu et al. Nature Communications
- Kinetic ensemble model of gas fermenting Clostridium autoethanogenum for improved ethanol production
- (2019) Jennifer Greene et al. BIOCHEMICAL ENGINEERING JOURNAL
- Multi-Omics Analysis of Fatty Alcohol Production in Engineered Yeasts Saccharomyces cerevisiae and Yarrowia lipolytica
- (2019) Jonathan Dahlin et al. Frontiers in Genetics
- Understanding and eliminating the detrimental effect of thiamine deficiency on the oleaginous yeast Yarrowia lipolytica
- (2019) Caleb Walker et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- Yarrowia lipolytica: more than an oleaginous workhorse
- (2019) Kelly K. Miller et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- Advances and opportunities in gene editing and gene regulation technology for Yarrowia lipolytica
- (2019) Vijaydev Ganesan et al. Microbial Cell Factories
- Metabolic engineering for enhancing microbial biosynthesis of advanced biofuels
- (2019) Manali Das et al. RENEWABLE & SUSTAINABLE ENERGY REVIEWS
- Mixed carbon substrates: a necessary nuisance or a missed opportunity?
- (2019) Nian Liu et al. CURRENT OPINION IN BIOTECHNOLOGY
- Machine learning applications in systems metabolic engineering
- (2019) Gi Bae Kim et al. CURRENT OPINION IN BIOTECHNOLOGY
- Comparative transcriptome analysis reveals multiple functions for Mhy1p in lipid biosynthesis in the oleaginous yeast Yarrowia lipolytica
- (2018) Guangyuan Wang et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Implementing CRISPR-Cas technologies in conventional and non-conventional yeasts: Current state and future prospects
- (2018) Hana Raschmanová et al. BIOTECHNOLOGY ADVANCES
- Engineering global transcription to tune lipophilic properties in Yarrowia lipolytica
- (2018) Man Wang et al. Biotechnology for Biofuels
- Multiplexed CRISPR Activation of Cryptic Sugar Metabolism Enables Yarrowia Lipolytica Growth on Cellobiose
- (2018) Cory Schwartz et al. Biotechnology Journal
- EasyCloneYALI: CRISPR/Cas9-Based Synthetic Toolbox for Engineering of the Yeast Yarrowia lipolytica
- (2018) Carina Holkenbrink et al. Biotechnology Journal
- Engineering Yarrowia lipolytica for Use in Biotechnological Applications: A Review of Major Achievements and Recent Innovations
- (2018) Catherine Madzak MOLECULAR BIOTECHNOLOGY
- Holistic Approaches in Lipid Production by Yarrowia lipolytica
- (2018) Zbigniew Lazar et al. TRENDS IN BIOTECHNOLOGY
- Synthetic Biology Expands the Industrial Potential of Yarrowia lipolytica
- (2018) Kelly A. Markham et al. TRENDS IN BIOTECHNOLOGY
- Multiplexed CRISPR Activation of Cryptic Sugar Metabolism Enables Yarrowia Lipolytica Growth on Cellobiose
- (2018) Cory Schwartz et al. Biotechnology Journal
- EasyCloneYALI: CRISPR/Cas9-Based Synthetic Toolbox for Engineering of the Yeast Yarrowia lipolytica
- (2018) Carina Holkenbrink et al. Biotechnology Journal
- Metabolic engineering in the host Yarrowia lipolytica
- (2018) Ahmad M. Abdel-Mawgoud et al. METABOLIC ENGINEERING
- Planning chemical syntheses with deep neural networks and symbolic AI
- (2018) Marwin H. S. Segler et al. NATURE
- Identifying mechanisms of regulation to model carbon flux during heat stress and generate testable hypotheses
- (2018) Allen H. Hubbard et al. PLoS One
- Machine learning applied to enzyme turnover numbers reveals protein structural correlates and improves metabolic models
- (2018) David Heckmann et al. Nature Communications
- Engineering of unconventional yeast Yarrowia lipolytica for efficient succinic acid production from glycerol at low pH
- (2017) Zhiyong Cui et al. METABOLIC ENGINEERING
- Substrates and oxygen dependent citric acid production by Yarrowia lipolytica: insights through transcriptome and fluxome analyses
- (2017) Wael Sabra et al. Microbial Cell Factories
- Improving the phenotype predictions of a yeast genome‐scale metabolic model by incorporating enzymatic constraints
- (2017) Benjamín J Sánchez et al. Molecular Systems Biology
- The Impact of Systems Biology on Bioprocessing
- (2017) Kate Campbell et al. TRENDS IN BIOTECHNOLOGY
- Leucine Biosynthesis Is Involved in Regulating High Lipid Accumulation in Yarrowia lipolytica
- (2017) Eduard J. Kerkhoven et al. mBio
- Single Cell Protein—State-of-the-Art, Industrial Landscape and Patents 2001–2016
- (2017) Anneli Ritala et al. Frontiers in Microbiology
- A novel constructed SPT15 mutagenesis library of Saccharomyces cerevisiae by using gTME technique for enhanced ethanol production
- (2017) Ashraf A. M. M. El-Rotail et al. AMB Express
- The contribution of microbial biotechnology to sustainable development goals
- (2017) Kenneth Timmis et al. Microbial Biotechnology
- Applying pathway engineering to enhance production of alpha-ketoglutarate in Yarrowia lipolytica
- (2016) Hongwei Guo et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- Metabolic evolution and 13 C flux analysis of a succinate dehydrogenase deficient strain of Yarrowia lipolytica
- (2016) Tigran V. Yuzbashev et al. BIOTECHNOLOGY AND BIOENGINEERING
- Multi-omics analysis reveals regulators of the response to nitrogen limitation in Yarrowia lipolytica
- (2016) Kyle R. Pomraning et al. BMC GENOMICS
- Production of succinic acid by metabolically engineered microorganisms
- (2016) Jung Ho Ahn et al. CURRENT OPINION IN BIOTECHNOLOGY
- Lipid biosynthesis in yeasts: A comparison of the lipid biosynthetic pathway between the model nonoleaginous yeastSaccharomyces cerevisiaeand the model oleaginous yeastYarrowia lipolytica
- (2016) Stylianos Fakas ENGINEERING IN LIFE SCIENCES
- Itaconic acid – a versatile building block for renewable polyesters with enhanced functionality
- (2016) Tobias Robert et al. GREEN CHEMISTRY
- Comparative genomics analysis of a series of Yarrowia lipolytica WSH-Z06 mutants with varied capacity for α-ketoglutarate production
- (2016) Weizhu Zeng et al. JOURNAL OF BIOTECHNOLOGY
- Multiplex gene editing of the Yarrowia lipolytica genome using the CRISPR-Cas9 system
- (2016) Shuliang Gao et al. JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY
- 13 C Metabolic Flux Analysis of acetate conversion to lipids by Yarrowia lipolytica
- (2016) Nian Liu et al. METABOLIC ENGINEERING
- Model-based metabolic engineering enables high yield itaconic acid production by Escherichia coli
- (2016) Björn-Johannes Harder et al. METABOLIC ENGINEERING
- Using global transcription machinery engineering (gTME) to improve ethanol tolerance of Zymomonas mobilis
- (2016) Furong Tan et al. Microbial Cell Factories
- Yarrowia lipolytica as a biotechnological chassis to produce usual and unusual fatty acids
- (2016) Rodrigo Ledesma-Amaro et al. PROGRESS IN LIPID RESEARCH
- Semisupervised Gaussian Process for Automated Enzyme Search
- (2016) Joseph Mellor et al. ACS Synthetic Biology
- Synthetic RNA Polymerase III Promoters Facilitate High-Efficiency CRISPR–Cas9-Mediated Genome Editing in Yarrowia lipolytica
- (2016) Cory M. Schwartz et al. ACS Synthetic Biology
- Sustainable source of omega-3 eicosapentaenoic acid from metabolically engineered Yarrowia lipolytica: from fundamental research to commercial production
- (2015) Dongming Xie et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- Optimization of lipid production with a genome-scale model of Yarrowia lipolytica
- (2015) Martin Kavšček et al. BMC Systems Biology
- Metabolome analysis and pathway abundance profiling of Yarrowia lipolytica cultivated on different carbon sources
- (2015) Chen Zhao et al. JOURNAL OF BIOTECHNOLOGY
- Proteomic Analysis of Erythritol-Producing Yarrowia lipolytica from Glycerol in Response to Osmotic Pressure
- (2015) Li-Bo Yang et al. JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY
- The oxidative pentose phosphate pathway is the primary source of NADPH for lipid overproduction from glucose in Yarrowia lipolytica
- (2015) Thomas M. Wasylenko et al. METABOLIC ENGINEERING
- An evolutionary metabolic engineering approach for enhancing lipogenesis in Yarrowia lipolytica
- (2015) Leqian Liu et al. METABOLIC ENGINEERING
- Surveying the lipogenesis landscape in Yarrowia lipolytica through understanding the function of a Mga2p regulatory protein mutant
- (2015) Leqian Liu et al. METABOLIC ENGINEERING
- Metabolic engineering of Yarrowia lipolytica for itaconic acid production
- (2015) John Blazeck et al. METABOLIC ENGINEERING
- Identification and application of keto acids transporters in Yarrowia lipolytica
- (2015) Hongwei Guo et al. Scientific Reports
- Comprehensive Metabolomic, Lipidomic and Microscopic Profiling of Yarrowia lipolytica during Lipid Accumulation Identifies Targets for Increased Lipogenesis
- (2015) Kyle R. Pomraning et al. PLoS One
- Improving Production of Malonyl Coenzyme A-Derived Metabolites by Abolishing Snf1-Dependent Regulation of Acc1
- (2014) S. Shi et al. mBio
- Harnessing Yarrowia lipolytica lipogenesis to create a platform for lipid and biofuel production
- (2014) John Blazeck et al. Nature Communications
- Snf1 Is a Regulator of Lipid Accumulation in Yarrowia lipolytica
- (2013) John Seip et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- A novel osmotic pressure control fed-batch fermentation strategy for improvement of erythritol production by Yarrowia lipolytica from glycerol
- (2013) Li-Bo Yang et al. BIORESOURCE TECHNOLOGY
- Yarrowia lipolytica: Safety assessment of an oleaginous yeast with a great industrial potential
- (2013) Marizeth Groenewald et al. CRITICAL REVIEWS IN MICROBIOLOGY
- Genome-scale modeling enables metabolic engineering of Saccharomyces cerevisiae for succinic acid production
- (2013) Rasmus Agren et al. JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY
- Genome-scale models of metabolism and gene expression extend and refine growth phenotype prediction
- (2013) E. J. O{middle dot}Brien et al. Molecular Systems Biology
- Industrial Systems Biology of Saccharomyces cerevisiae Enables Novel Succinic Acid Cell Factory
- (2013) José Manuel Otero et al. PLoS One
- Disruption of the MIG1 gene enhances lipid biosynthesis in the oleaginous yeast Yarrowia lipolytica ACA-DC 50109
- (2012) Zhi-Peng Wang et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- A genome-scale metabolic model of the lipid-accumulating yeast Yarrowia lipolytica
- (2012) Nicolas Loira et al. BMC Systems Biology
- Reconstruction and In Silico Analysis of Metabolic Network for an Oleaginous Yeast, Yarrowia lipolytica
- (2012) Pengcheng Pan et al. PLoS One
- A multi-omic map of the lipid-producing yeast Rhodosporidium toruloides
- (2012) Zhiwei Zhu et al. Nature Communications
- Transcriptomic Analyses during the Transition from Biomass Production to Lipid Accumulation in the Oleaginous Yeast Yarrowia lipolytica
- (2011) Nicolas Morin et al. PLoS One
- Production of succinic acid at low pH by a recombinant strain of the aerobic yeast Yarrowia lipolytica
- (2010) Tigran V. Yuzbashev et al. BIOTECHNOLOGY AND BIOENGINEERING
- Yarrowia lipolytica: A model and a tool to understand the mechanisms implicated in lipid accumulation
- (2009) Athanasios Beopoulos et al. BIOCHIMIE
- Ensemble modeling for strain development of l-lysine-producing Escherichia coli
- (2009) Carolina A. Contador et al. METABOLIC ENGINEERING
- Cloning and functional characterization of the cis-aconitic acid decarboxylase (CAD) gene from Aspergillus terreus
- (2008) Shin Kanamasa et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- Ensemble Modeling of Metabolic Networks
- (2008) Linh M. Tran et al. BIOPHYSICAL JOURNAL
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation