Physiological and Pathological Factors Affecting Drug Delivery to the Brain by Nanoparticles
出版年份 2021 全文链接
标题
Physiological and Pathological Factors Affecting Drug Delivery to the Brain by Nanoparticles
作者
关键词
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出版物
Advanced Science
Volume -, Issue -, Pages 2002085
出版商
Wiley
发表日期
2021-03-15
DOI
10.1002/advs.202002085
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Microengineered human blood–brain barrier platform for understanding nanoparticle transport mechanisms
- (2020) Song Ih Ahn et al. Nature Communications
- Nanocatalytic activity of clean-surfaced, faceted nanocrystalline gold enhances remyelination in animal models of multiple sclerosis
- (2020) Andrew P. Robinson et al. Scientific Reports
- Effects of centrifugation and whole-body vibrations on blood–brain barrier permeability in mice
- (2020) David Dubayle et al. NPJ Microgravity
- Quercetin lipid nanoparticles functionalized with transferrin for Alzheimer's disease
- (2020) R.G.R Pinheiro et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Complement Activation: A Potential Threat on the Safety of Poly(ethylene glycol)-Coated Nanomedicines
- (2020) Alberto Gabizon et al. ACS Nano
- Anti-PEG antibodies: Properties, formation, testing and role in adverse immune reactions to PEGylated nano-biopharmaceuticals
- (2020) Gergely Tibor Kozma et al. ADVANCED DRUG DELIVERY REVIEWS
- The effects of nickel oxide nanoparticles on tau protein and neuron-like cells
- (2019) Mozhdeh Hajimohammadjafartehrani et al. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
- Nose-to-brain delivery of lamotrigine-loaded PLGA nanoparticles
- (2019) Kuldeep Nigam et al. Drug Delivery and Translational Research
- Superparamagnetic Iron Oxide Nanoparticles—Current and Prospective Medical Applications
- (2019) Joanna Dulińska-Litewka et al. Materials
- Systemic Delivery of Monoclonal Antibodies to the Central Nervous System for Brain Tumor Therapy
- (2019) Lei Han et al. ADVANCED MATERIALS
- Blood-brain barrier dysfunction underlying Alzheimer's disease is induced by an SSAO/VAP-1-dependent cerebrovascular activation with enhanced Aβ deposition
- (2019) Montse Solé et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Fluid–structure interaction for highly complex, statistically defined, biological media: Homogenisation and a 3D multi-compartmental poroelastic model for brain biomechanics
- (2019) John C. Vardakis et al. JOURNAL OF FLUIDS AND STRUCTURES
- Republished: Real-time MRI guidance for intra-arterial drug delivery in a patient with a brain tumor: technical note
- (2019) Michal Zawadzki et al. Journal of NeuroInterventional Surgery
- Vitamin D-binding protein-loaded PLGA nanoparticles suppress Alzheimer's disease-related pathology in 5XFAD mice
- (2019) Seong Gak Jeon et al. Nanomedicine-Nanotechnology Biology and Medicine
- Nanotechnology Meets Oncology: Nanomaterials in Brain Cancer Research, Diagnosis and Therapy
- (2019) Alja Zottel et al. Materials
- Pseudo-Anaphylaxis to Polyethylene Glycol (PEG)-Coated Liposomes: Roles of Anti-PEG IgM and Complement Activation in a Porcine Model of Human Infusion Reactions
- (2019) Gergely Tibor Kozma et al. ACS Nano
- Biodegradable polymeric nanoparticles administered in the cerebrospinal fluid: Brain biodistribution, preferential internalization in microglia and implications for cell-selective drug release
- (2019) Marco Peviani et al. BIOMATERIALS
- Targeted anticancer potential against glioma cells of thymoquinone delivered by mesoporous silica core-shell nanoformulations with pH-dependent release
- (2019) Samar A Shahein et al. International Journal of Nanomedicine
- α-synuclein interaction with zero-valent iron nanoparticles accelerates structural rearrangement into amyloid-susceptible structure with increased cytotoxic tendency
- (2019) Seyedeh Sahar Tahaei Gilan et al. International Journal of Nanomedicine
- Drug pipeline 1Q19
- (2019) Laura DeFrancesco NATURE BIOTECHNOLOGY
- Pericyte loss leads to circulatory failure and pleiotrophin depletion causing neuron loss
- (2019) Angeliki M. Nikolakopoulou et al. NATURE NEUROSCIENCE
- Intravenous infusion of mesenchymal stem cells improves impaired cognitive function in a cerebral small vessel disease model
- (2019) Masahito Nakazaki et al. NEUROSCIENCE
- Development and screening of brain-targeted lipid-based nanoparticles with enhanced cell penetration and gene delivery properties
- (2019) Bruna dos Santos Rodrigues et al. International Journal of Nanomedicine
- Panax notoginseng saponins suppress lipopolysaccharide‐induced barrier disruption and monocyte adhesion on bEnd.3 cells via the opposite modulation of Nrf2 antioxidant and NF‐κB inflammatory pathways
- (2019) Shaonan Hu et al. PHYTOTHERAPY RESEARCH
- MicroRNA-126-3p Attenuates Intracerebral Hemorrhage-Induced Blood-Brain Barrier Disruption by Regulating VCAM-1 Expression
- (2019) Xi Fu et al. Frontiers in Neuroscience
- Blood-brain barrier leakage of blood proteins in idiopathic normal pressure hydrocephalus
- (2019) Per Kristian Eide et al. BRAIN RESEARCH
- The Effect of Biotinylated PAMAM G3 Dendrimers Conjugated with COX-2 Inhibitor (celecoxib) and PPARγ Agonist (Fmoc-L-Leucine) on Human Normal Fibroblasts, Immortalized Keratinocytes and Glioma Cells in Vitro
- (2019) Łukasz Uram et al. MOLECULES
- Blood-brain barrier disruption and inflammation reaction in mice after chronic exposure to Microcystin-LR
- (2019) Jing Wang et al. SCIENCE OF THE TOTAL ENVIRONMENT
- Brain-targeted drug delivery by manipulating protein corona functions
- (2019) Zui Zhang et al. Nature Communications
- Crossing the blood-brain-barrier with nanoligand drug carriers self-assembled from a phage display peptide
- (2019) Lin-Ping Wu et al. Nature Communications
- Methylene Blue Reduces Neuronal Apoptosis and Improves Blood-Brain Barrier Integrity After Traumatic Brain Injury
- (2019) Jun Shen et al. Frontiers in Neurology
- Neuroprotective Action of Teriflunomide in a Mouse Model of Transient Middle Cerebral Artery Occlusion
- (2019) Zhengfang Lu et al. NEUROSCIENCE
- Convective influx/glymphatic system: tracers injected into the CSF enter and leave the brain along separate periarterial basement membrane pathways
- (2018) Nazira J. Albargothy et al. ACTA NEUROPATHOLOGICA
- The meninges as barriers and facilitators for the movement of fluid, cells and pathogens related to the rodent and human CNS
- (2018) Roy O. Weller et al. ACTA NEUROPATHOLOGICA
- Multiwalled Carbon Nanotubes Induced Hypotension by Regulating the Central Nervous System
- (2018) Xiaowei Ma et al. ADVANCED FUNCTIONAL MATERIALS
- Co-administration of liposomal fasudil and tissue plasminogen activator ameliorated ischemic brain damage in occlusion model rats prepared by photochemically induced thrombosis
- (2018) Tatsuya Fukuta et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Plasma Pharmacokinetics of Valanafusp Alpha, a Human Insulin Receptor Antibody-Iduronidase Fusion Protein, in Patients with Mucopolysaccharidosis Type I
- (2018) William M. Pardridge et al. BIODRUGS
- 3D self-organized microvascular model of the human blood-brain barrier with endothelial cells, pericytes and astrocytes
- (2018) Marco Campisi et al. BIOMATERIALS
- In vitro models of molecular and nano-particle transport across the blood-brain barrier
- (2018) Cynthia Hajal et al. Biomicrofluidics
- Using microfluidic platforms to develop CNS-targeted polymeric nanoparticles for HIV therapy
- (2018) Cláudia Martins et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Mimicking brain tissue binding in an in vitro model of the blood-brain barrier illustrates differences between in vitro and in vivo methods for assessing the rate of brain penetration
- (2018) Marjolein Heymans et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Silica nanoparticle-induced oxidative stress and mitochondrial damage is followed by activation of intrinsic apoptosis pathway in glioblastoma cells
- (2018) Magdalena Kusaczuk et al. International Journal of Nanomedicine
- Intranasal delivery of Huperzine A to the brain using lactoferrin-conjugated N-trimethylated chitosan surface-modified PLGA nanoparticles for treatment of Alzheimer’s disease
- (2018) Qingqing Meng et al. International Journal of Nanomedicine
- Direct modulation of myelin-autoreactive CD4+ and CD8+ T cells in EAE mice by a tolerogenic nanoparticle co-carrying myelin peptide-loaded major histocompatibility complexes, CD47 and multiple regulatory molecules
- (2018) Weiya Pei et al. International Journal of Nanomedicine
- Nanoparticle formulations that allow for sustained delivery and brain targeting of the neuropeptide oxytocin
- (2018) Rokon Uz Zaman et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Complement activation in vitro and reactogenicity of low-molecular weight dextran-coated SPIONs in the pig CARPA model: Correlation with physicochemical features and clinical information
- (2018) Tamás Fülöp et al. JOURNAL OF CONTROLLED RELEASE
- Systemic delivery of BACE1 siRNA through neuron-targeted nanocomplexes for treatment of Alzheimer's disease
- (2018) Pengzhen Wang et al. JOURNAL OF CONTROLLED RELEASE
- Vascular adhesion protein-1 is actively involved in the development of inflammatory lesions in rat models of multiple sclerosis
- (2018) Petri Elo et al. Journal of Neuroinflammation
- Green synthesized silver nanoparticles: Catalytic dye degradation, in vitro anticancer activity and in vivo toxicity in rats
- (2018) Jayachandra Reddy Nakkala et al. Materials Science & Engineering C-Materials for Biological Applications
- Targeted Doxorubicin-Loaded Bacterially Derived Nano-Cells for the Treatment of Neuroblastoma
- (2018) Sharon M. Sagnella et al. MOLECULAR CANCER THERAPEUTICS
- Targeted mRNA Therapy for Ornithine Transcarbamylase Deficiency
- (2018) Mary G. Prieve et al. MOLECULAR THERAPY
- Understanding the Role of Anti-PEG Antibodies in the Complement Activation by Doxil in Vitro
- (2018) Barry Neun et al. MOLECULES
- TAT-modified self-assembled cationic peptide nanoparticles as an efficient antibacterial agent
- (2018) Bi He et al. Nanomedicine-Nanotechnology Biology and Medicine
- Neuroprotective effect of gold nanoparticles composites in Parkinson's disease model
- (2018) Kaikai Hu et al. Nanomedicine-Nanotechnology Biology and Medicine
- Comparison Between Folic Acid and gH625 Peptide-Based Functionalization of Fe3O4 Magnetic Nanoparticles for Enhanced Cell Internalization
- (2018) C. Tudisco et al. Nanoscale Research Letters
- Aging-associated changes in cerebral vasculature and blood flow as determined by quantitative optical coherence tomography angiography
- (2018) Yuandong Li et al. NEUROBIOLOGY OF AGING
- The effects of cerebral amyloid angiopathy on integrity of the blood-brain barrier
- (2018) Shino Magaki et al. NEUROBIOLOGY OF AGING
- Intravenous administration of the adeno-associated virus-PHP.B capsid fails to upregulate transduction efficiency in the marmoset brain
- (2018) Yasunori Matsuzaki et al. NEUROSCIENCE LETTERS
- Characterization of superparamagnetic iron oxide nanoparticle-induced apoptosis in PC12 cells and mouse hippocampus and striatum
- (2018) Yutong Liu et al. TOXICOLOGY LETTERS
- Human Cortex Spheroid with a Functional Blood Brain Barrier for High-Throughput Neurotoxicity Screening and Disease Modeling
- (2018) Goodwell Nzou et al. Scientific Reports
- Immunosilencing peptides by stereochemical inversion and sequence reversal: retro-D-peptides
- (2018) Pol Arranz-Gibert et al. Scientific Reports
- Metastatic Brain Tumors Disrupt the Blood-Brain Barrier and Alter Lipid Metabolism by Inhibiting Expression of the Endothelial Cell Fatty Acid Transporter Mfsd2a
- (2018) Shweta Tiwary et al. Scientific Reports
- Nano-particle mediated inhibition of Parkinson’s disease using computational biology approach
- (2018) Aman Chandra Kaushik et al. Scientific Reports
- Targeted Delivery of Functionalized Upconversion Nanoparticles for Externally Triggered Photothermal/Photodynamic Therapies of Brain Glioblastoma
- (2018) Yuan-Chung Tsai et al. Theranostics
- Self-assembled RNAi nanoflowers via rolling circle transcription for aptamer-targeted siRNA delivery
- (2018) Hui Cheng et al. Journal of Materials Chemistry B
- Adeno-Associated Viral Vector (Serotype 2)–Nerve Growth Factor for Patients With Alzheimer Disease
- (2018) Michael S. Rafii et al. JAMA Neurology
- Comparison Between Folic Acid and gH625 Peptide-Based Functionalization of Fe3O4 Magnetic Nanoparticles for Enhanced Cell Internalization
- (2018) C. Tudisco et al. Nanoscale Research Letters
- Spherical Nucleic Acid Architecture Can Improve the Efficacy of Polycation-Mediated siRNA Delivery
- (2018) Jilian R. Melamed et al. Molecular Therapy-Nucleic Acids
- Thrombin-Responsive, Brain-Targeting Nanoparticles for Improved Stroke Therapy
- (2018) Xing Guo et al. ACS Nano
- AGuIX® from bench to bedside—Transfer of an ultrasmall theranostic gadolinium-based nanoparticle to clinical medicine
- (2018) François Lux et al. BRITISH JOURNAL OF RADIOLOGY
- Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
- (2018) Freddie Bray et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Conjugation of vitamin E-TPGS and guar gum to carry borneol for enhancing blood–brain barrier permeability
- (2018) Yude Liu et al. JOURNAL OF BIOMATERIALS APPLICATIONS
- In-vitro blood–brain barrier modeling: A review of modern and fast-advancing technologies
- (2018) Farzane Sivandzade et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- A filter-free blood-brain barrier model to quantitatively study transendothelial delivery of nanoparticles by fluorescence spectroscopy
- (2018) Edwin De Jong et al. JOURNAL OF CONTROLLED RELEASE
- Dual functionalized liposome-mediated gene delivery across triple co-culture blood brain barrier model and specific in vivo neuronal transfection
- (2018) Bruna dos Santos Rodrigues et al. JOURNAL OF CONTROLLED RELEASE
- Dual Functionalized 5-Fluorouracil Liposomes as Highly Efficient Nanomedicine for Glioblastoma Treatment as Assessed in an In Vitro Brain Tumor Model
- (2018) Sushant Lakkadwala et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Primary brain tumours in adults
- (2018) Sarah Lapointe et al. LANCET
- L-DOPA functionalized, multi-branched gold nanoparticles as brain-targeted nano-vehicles
- (2018) Daniel Gonzalez-Carter et al. Nanomedicine-Nanotechnology Biology and Medicine
- CBTRUS Statistical Report: Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2011–2015
- (2018) Quinn T Ostrom et al. NEURO-ONCOLOGY
- Vascular and Neurogenic Rejuvenation in Aging Mice by Modulation of ASM
- (2018) Min Hee Park et al. NEURON
- Targeted cancer therapy using engineered exosome as a natural drug delivery vehicle
- (2018) Hosna Gomari et al. OncoTargets and Therapy
- Emerging Technologies for Delivery of Biotherapeutics and Gene Therapy Across the Blood–Brain Barrier
- (2018) Danica B. Stanimirovic et al. BIODRUGS
- Involvement of complement activation in the pulmonary vasoactivity of polystyrene nanoparticles in pigs: unique surface properties underlying alternative pathway activation and instant opsonization
- (2018) Tamás Mészáros et al. International Journal of Nanomedicine
- Age-related ultrastructural changes of the basement membrane in the mouse blood-brain barrier
- (2018) Laura Cristina Ceafalan et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- PAMAM dendrimers: blood-brain barrier transport and neuronal uptake after focal brain ischemia
- (2018) Sofia D. Santos et al. JOURNAL OF CONTROLLED RELEASE
- A novel synthesis of selenium nanoparticles encapsulated PLGA nanospheres with curcumin molecules for the inhibition of amyloid β aggregation in Alzheimer's disease
- (2018) Xinlong Huo et al. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
- Evaluation of biomimetically synthesized mesoporous silica nanoparticles as drug carriers: Structure, wettability, degradation, biocompatibility and brain distribution
- (2018) Heran Li et al. Materials Science & Engineering C-Materials for Biological Applications
- Curcumin-loaded chitosan–bovine serum albumin nanoparticles potentially enhanced Aβ 42 phagocytosis and modulated macrophage polarization in Alzheimer’s disease
- (2018) Rui Yang et al. Nanoscale Research Letters
- Activated Microglia Disrupt the Blood-Brain Barrier and Induce Chemokines and Cytokines in a Rat in vitro Model
- (2018) Yukari Shigemoto-Mogami et al. Frontiers in Cellular Neuroscience
- Cloaking nanoparticles with protein corona shield for targeted drug delivery
- (2018) Jun Yong Oh et al. Nature Communications
- Microenvironment Remodeling Micelles for Alzheimer's Disease Therapy by Early Modulation of Activated Microglia
- (2018) Yifei Lu et al. Advanced Science
- Small interfering RNA delivery to the neurons near the amyloid plaques for improved treatment of Alzheimer's disease
- (2018) Qian Guo et al. Acta Pharmaceutica Sinica B
- Endothelial damage, vascular bagging and remodeling of the microvascular bed in human microangiopathy with deep white matter lesions
- (2018) Karin M. E. Forsberg et al. Acta Neuropathologica Communications
- Ferumoxytol-enhanced magnetic resonance imaging assessing inflammation after myocardial infarction
- (2017) Colin G Stirrat et al. HEART
- Novel dendritic structure of alginate hybrid nanoparticles for effective anti-viral drug delivery
- (2017) K.S. Joshy et al. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
- Wheat germ agglutinin-conjugated liposomes incorporated with cardiolipin to improve neuronal survival in Alzheimer’s disease treatment
- (2017) Yung-Chih Kuo et al. International Journal of Nanomedicine
- Convection enhanced delivery of panobinostat (LBH589)-loaded pluronic nano-micelles prolongs survival in the F98 rat glioma model
- (2017) WG Singleton et al. International Journal of Nanomedicine
- Non-immunogenic dextran-coated superparamagnetic iron oxide nanoparticles: a biocompatible, size-tunable contrast agent for magnetic resonance imaging
- (2017) Harald Unterweger et al. International Journal of Nanomedicine
- Aptamer-conjugated PEGylated quantum dots targeting epidermal growth factor receptor variant III for fluorescence imaging of glioma
- (2017) Jiaze Tang et al. International Journal of Nanomedicine
- Anti-Alzheimer's potential of berberine using surface decorated multi-walled carbon nanotubes: A preclinical evidence
- (2017) Shikha Lohan et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Molecular characterization of perivascular drainage pathways in the murine brain
- (2017) Melanie-Jane Hannocks et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Blood-Brain Barrier Disruption Is Initiated During Primary HIV Infection and Not Rapidly Altered by Antiretroviral Therapy
- (2017) Elham Rahimy et al. JOURNAL OF INFECTIOUS DISEASES
- Aptamer Functionalization of Nanosystems for Glioblastoma Targeting through the Blood–Brain Barrier
- (2017) Ilaria Monaco et al. JOURNAL OF MEDICINAL CHEMISTRY
- Aptamers as Valuable Molecular Tools in Neurosciences
- (2017) Olga Wolter et al. JOURNAL OF NEUROSCIENCE
- Bile acid quantification of 20 plasma metabolites identifies lithocholic acid as a putative biomarker in Alzheimer’s disease
- (2017) Josef Marksteiner et al. Metabolomics
- Brain and Organ Uptake in the Rhesus Monkey in Vivo of Recombinant Iduronidase Compared to an Insulin Receptor Antibody–Iduronidase Fusion Protein
- (2017) Ruben J. Boado et al. MOLECULAR PHARMACEUTICS
- Resveratrol and Grape Extract-loaded Solid Lipid Nanoparticles for the Treatment of Alzheimer’s Disease
- (2017) Joana Loureiro et al. MOLECULES
- Application of Europium-Doped Very Small Iron Oxide Nanoparticles to Visualize Neuroinflammation with MRI and Fluorescence Microscopy
- (2017) Jason M. Millward et al. NEUROSCIENCE
- Self-Assembled Aptamer-Nanomedicine for Targeted Chemotherapy and Gene Therapy
- (2017) Nianxi Zhao et al. Small
- Blood-brain-barrier spheroids as an in vitro screening platform for brain-penetrating agents
- (2017) Choi-Fong Cho et al. Nature Communications
- PLGA nanoparticles modified with a BBB-penetrating peptide co-delivering Aβ generation inhibitor and curcumin attenuate memory deficits and neuropathology in Alzheimer’s disease mice
- (2017) Na Huang et al. Oncotarget
- Vectorized nanodelivery systems for ischemic stroke: a concept and a need
- (2017) Andrés Da Silva-Candal et al. JOURNAL OF NANOBIOTECHNOLOGY
- Association of Perivascular Localization of Aquaporin-4 With Cognition and Alzheimer Disease in Aging Brains
- (2017) Douglas M. Zeppenfeld et al. JAMA Neurology
- Establishment of a Human Blood-Brain Barrier Co-culture Model Mimicking the Neurovascular Unit Using Induced Pluri- and Multipotent Stem Cells
- (2017) Antje Appelt-Menzel et al. Stem Cell Reports
- Silver nanoparticles reduce brain inflammation and related neurotoxicity through induction of H2S-synthesizing enzymes
- (2017) Daniel A. Gonzalez-Carter et al. Scientific Reports
- Brain Inflammation, Blood Brain Barrier dysfunction and Neuronal Synaptophysin Decrease after Inhalation Exposure to Titanium Dioxide Nano-aerosol in Aging Rats
- (2017) Clémence Disdier et al. Scientific Reports
- Increased Gold Nanoparticle Retention in Brain Tumors by in Situ Enzyme-Induced Aggregation
- (2016) Shaobo Ruan et al. ACS Nano
- Vascular basement membranes as pathways for the passage of fluid into and out of the brain
- (2016) Alan W. J. Morris et al. ACTA NEUROPATHOLOGICA
- Nanoparticles restore lysosomal acidification defects: Implications for Parkinson and other lysosomal-related diseases
- (2016) Mathieu Bourdenx et al. Autophagy
- Neurovascular dysfunction and neurodegeneration in dementia and Alzheimer's disease
- (2016) Amy R. Nelson et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Structure and function of legumain in health and disease
- (2016) Elfriede Dall et al. BIOCHIMIE
- Intravenous administration of brain-targeted stable nucleic acid lipid particles alleviates Machado-Joseph disease neurological phenotype
- (2016) Mariana Conceição et al. BIOMATERIALS
- Soluble and immobilized graphene oxide activates complement system differently dependent on surface oxidation state
- (2016) Peter P. Wibroe et al. BIOMATERIALS
- Brain-targeted co-delivery of therapeutic gene and peptide by multifunctional nanoparticles in Alzheimer's disease mice
- (2016) Yang Liu et al. BIOMATERIALS
- Cellular uptake of PLGA nanoparticles targeted with anti-amyloid and anti-transferrin receptor antibodies for Alzheimer’s disease treatment
- (2016) Joana A. Loureiro et al. COLLOIDS AND SURFACES B-BIOINTERFACES
- Interplay between Matrix Metalloproteinase-9, Matrix Metalloproteinase-2, and Interleukins in Multiple Sclerosis Patients
- (2016) Alessandro Trentini et al. DISEASE MARKERS
- Development of TIMP1 magnetic nanoformulation for regulation of synaptic plasticity in HIV-1 infection
- (2016) Venkata Atluri et al. International Journal of Nanomedicine
- Anti-glioma activity and the mechanism of cellular uptake of asiatic acid-loaded solid lipid nanoparticles
- (2016) Tanem Garanti et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Neuroprotection against cerebral ischemia/reperfusion injury by intravenous administration of liposomal fasudil
- (2016) Tatsuya Fukuta et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Pre-existing anti-PEG antibodies are associated with severe immediate allergic reactions to pegnivacogin, a PEGylated aptamer
- (2016) Thomas J. Povsic et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Neuropilin-1 modulates interferon-γ-stimulated signaling in brain microvascular endothelial cells
- (2016) Ying Wang et al. JOURNAL OF CELL SCIENCE
- In vitro models of the blood–brain barrier: An overview of commonly used brain endothelial cell culture models and guidelines for their use
- (2016) Hans C Helms et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Kinetics of functionalised carbon nanotube distribution in mouse brain after systemic injection: Spatial to ultra-structural analyses
- (2016) Julie T.-W. Wang et al. JOURNAL OF CONTROLLED RELEASE
- MicroRNA-124 loaded nanoparticles enhance brain repair in Parkinson's disease
- (2016) C. Saraiva et al. JOURNAL OF CONTROLLED RELEASE
- Tumor-specific pH-responsive peptide-modified pH-sensitive liposomes containing doxorubicin for enhancing glioma targeting and anti-tumor activity
- (2016) Yang Zhao et al. JOURNAL OF CONTROLLED RELEASE
- Dual targeted nanocarrier for brain ischemic stroke treatment
- (2016) Yue Zhao et al. JOURNAL OF CONTROLLED RELEASE
- SPARC expression by cerebral microvascular endothelial cells in vitro and its influence on blood-brain barrier properties
- (2016) Samir Alkabie et al. Journal of Neuroinflammation
- Microglial migration and interactions with dendrimer nanoparticles are altered in the presence of neuroinflammation
- (2016) Fan Zhang et al. Journal of Neuroinflammation
- Effect of PEGylated superparamagnetic iron oxide nanoparticles (SPIONs) under magnetic field on amyloid beta fibrillation process
- (2016) Somayeh Mirsadeghi et al. Materials Science & Engineering C-Materials for Biological Applications
- Anthocyanin-Loaded PEG-Gold Nanoparticles Enhanced the Neuroprotection of Anthocyanins in an Aβ1–42 Mouse Model of Alzheimer’s Disease
- (2016) Tahir Ali et al. MOLECULAR NEUROBIOLOGY
- Safety and Efficacy in Advanced Solid Tumors of a Targeted Nanocomplex Carrying the p53 Gene Used in Combination with Docetaxel: A Phase 1b Study
- (2016) Kathleen F Pirollo et al. MOLECULAR THERAPY
- Targeted drug delivery to ischemic stroke via chlorotoxin-anchored, lexiscan-loaded nanoparticles
- (2016) Liang Han et al. Nanomedicine-Nanotechnology Biology and Medicine
- Complement proteins bind to nanoparticle protein corona and undergo dynamic exchange in vivo
- (2016) Fangfang Chen et al. Nature Nanotechnology
- Protein adsorption is required for stealth effect of poly(ethylene glycol)- and poly(phosphoester)-coated nanocarriers
- (2016) Susanne Schöttler et al. Nature Nanotechnology
- Brain-targeted delivery of resveratrol using solid lipid nanoparticles functionalized with apolipoprotein E
- (2016) Ana Rute Neves et al. JOURNAL OF NANOBIOTECHNOLOGY
- Blood–brain barrier and intestinal epithelial barrier alterations in autism spectrum disorders
- (2016) Maria Fiorentino et al. Molecular Autism
- In vitro toxicity evaluation of silica-coated iron oxide nanoparticles in human SHSY5Y neuronal cells
- (2016) Gözde Kiliç et al. Toxicology Research
- Rapamycin Loaded Solid Lipid Nanoparticles as a New Tool to Deliver mTOR Inhibitors: Formulation and in Vitro Characterization
- (2016) Alice Polchi et al. Nanomaterials
- Targeted Polymeric Nanoparticles for Brain Delivery of High Molecular Weight Molecules in Lysosomal Storage Disorders
- (2016) Marika Salvalaio et al. PLoS One
- The role of pericytic laminin in blood brain barrier integrity maintenance
- (2016) Jyoti Gautam et al. Scientific Reports
- Nose-To-Brain Delivery of PLGA-Diazepam Nanoparticles
- (2015) Deepak Sharma et al. AAPS PHARMSCITECH
- Modulatory Role of Surface Coating of Superparamagnetic Iron Oxide Nanoworms in Complement Opsonization and Leukocyte Uptake
- (2015) Swetha Inturi et al. ACS Nano
- Sialic acid (SA)-modified selenium nanoparticles coated with a high blood–brain barrier permeability peptide-B6 peptide for potential use in Alzheimer’s disease
- (2015) Tiantian Yin et al. Acta Biomaterialia
- Protein Corona of Nanoparticles: Distinct Proteins Regulate the Cellular Uptake
- (2015) Sandra Ritz et al. BIOMACROMOLECULES
- The impact of cationic solid lipid nanoparticles on human neutrophil activation and formation of neutrophil extracellular traps (NETs)
- (2015) Tsong-Long Hwang et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Aptamer for imaging and therapeutic targeting of brain tumor glioblastoma
- (2015) Mateja Delač et al. CYTOMETRY PART A
- Galantamine-loaded solid–lipid nanoparticles for enhanced brain delivery: preparation, characterization,in vitroandin vivoevaluations
- (2015) Shubham Misra et al. DRUG DELIVERY
- Flow cytometry evaluation of in vitro cellular necrosis and apoptosis induced by silver nanoparticles
- (2015) Girish Kumar et al. FOOD AND CHEMICAL TOXICOLOGY
- Blood–brain barrier transport studies, aggregation, and molecular dynamics simulation of multiwalled carbon nanotube functionalized with fluorescein isothiocyanate
- (2015) Sergey Shityakov et al. International Journal of Nanomedicine
- Accelerated pericyte degeneration and blood–brain barrier breakdown in apolipoprotein E4 carriers with Alzheimer’s disease
- (2015) Matthew R Halliday et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Striatal Blood–Brain Barrier Permeability in Parkinson'S Disease
- (2015) Madison T Gray et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Safety and tolerability of intracerebroventricular PDGF-BB in Parkinson’s disease patients
- (2015) Gesine Paul et al. JOURNAL OF CLINICAL INVESTIGATION
- First in human nanotechnology doxorubicin delivery system to target epidermal growth factor receptors in recurrent glioblastoma
- (2015) James R. Whittle et al. JOURNAL OF CLINICAL NEUROSCIENCE
- A dural lymphatic vascular system that drains brain interstitial fluid and macromolecules
- (2015) Aleksanteri Aspelund et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Aβ1-42oligomer-induced leakage in anin vitroblood-brain barrier model is associated with up-regulation of RAGE and metalloproteinases, and down-regulation of tight junction scaffold proteins
- (2015) Wenbin Wan et al. JOURNAL OF NEUROCHEMISTRY
- Amyloid Oligomers Disrupt Blood-CSF Barrier Integrity by Activating Matrix Metalloproteinases
- (2015) M. Brkic et al. JOURNAL OF NEUROSCIENCE
- Intranasal Piperine-Loaded Chitosan Nanoparticles as Brain-Targeted Therapy in Alzheimer's Disease: Optimization, Biological Efficacy, and Potential Toxicity
- (2015) Yosra S.R. Elnaggar et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- A randomized, double-blind phase I/IIa study of intranasal glutathione in Parkinson's disease
- (2015) Laurie K. Mischley et al. MOVEMENT DISORDERS
- Repeated intraperitoneal injections of liposomes containing phosphatidic acid and cardiolipin reduce amyloid-β levels in APP/PS1 transgenic mice
- (2015) Lara Ordóñez-Gutiérrez et al. Nanomedicine-Nanotechnology Biology and Medicine
- Matrix metalloproteinase triggered size-shrinkable gelatin-gold fabricated nanoparticles for tumor microenvironment sensitive penetration and diagnosis of glioma
- (2015) Shaobo Ruan et al. Nanoscale
- Solid lipid nanoparticles as a vehicle for brain-targeted drug delivery: two new strategies of functionalization with apolipoprotein E
- (2015) Ana Rute Neves et al. NANOTECHNOLOGY
- GLUT1 reductions exacerbate Alzheimer's disease vasculo-neuronal dysfunction and degeneration
- (2015) Ethan A Winkler et al. NATURE NEUROSCIENCE
- Fibrin deposited in the Alzheimer's disease brain promotes neuronal degeneration
- (2015) Marta Cortes-Canteli et al. NEUROBIOLOGY OF AGING
- P-glycoprotein expression and amyloid accumulation in human aging and Alzheimer's disease: preliminary observations
- (2015) Catherine Chiu et al. NEUROBIOLOGY OF AGING
- Blood-Brain Barrier Breakdown in the Aging Human Hippocampus
- (2015) Axel Montagne et al. NEURON
- Early changes in extracellular matrix in Alzheimer's disease
- (2015) F.-X. Lepelletier et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- Polymerized nano-curcumin attenuates neurological symptoms in EAE model of multiple sclerosis through down regulation of inflammatory and oxidative processes and enhancing neuroprotection and myelin repair
- (2015) Maryam Mohajeri et al. NEUROPHARMACOLOGY
- Effects of Injection of Carbon Nanotubes on EEG and Results of a Behavioral Test in Rats
- (2015) V. Azimirad et al. NEUROPHYSIOLOGY
- Anti-PEG immunity: emergence, characteristics, and unaddressed questions
- (2015) Qi Yang et al. Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology
- Choroid plexus dysfunction impairs beta-amyloid clearance in a triple transgenic mouse model of Alzheimer’s disease
- (2015) Ibrahim González-Marrero et al. Frontiers in Cellular Neuroscience
- Increased cerebrospinal fluid fibrinogen in major depressive disorder
- (2015) Kotaro Hattori et al. Scientific Reports
- Regulating Biocompatibility of Carbon Spheres via Defined Nanoscale Chemistry and a Careful Selection of Surface Functionalities
- (2015) Santosh K. Misra et al. Scientific Reports
- Cargo Delivery into the Brain by in vivo identified Transport Peptides
- (2015) Eduard Urich et al. Scientific Reports
- Retinoic acid-loaded polymeric nanoparticles induce neuroprotection in a mouse model for Parkinson's disease
- (2015) Marta Esteves et al. Frontiers in Aging Neuroscience
- PEGylated Carbon Nanotubes Impair Retrieval of Contextual Fear Memory and Alter Oxidative Stress Parameters in the Rat Hippocampus
- (2015) Lidiane Dal Bosco et al. Biomed Research International
- Transcytosis in the blood–cerebrospinal fluid barrier of the mouse brain with an engineered receptor/ligand system
- (2015) Héctor R Méndez-Gómez et al. Molecular Therapy-Methods & Clinical Development
- Nano-Drugs Based on Nano Sterically Stabilized Liposomes for the Treatment of Inflammatory Neurodegenerative Diseases
- (2015) Keren Turjeman et al. PLoS One
- A phase1 study of stereotactic gene delivery of AAV2-NGF for Alzheimer's disease
- (2014) Michael S. Rafii et al. Alzheimers & Dementia
- Impairment of paravascular clearance pathways in the aging brain
- (2014) Benjamin T. Kress et al. ANNALS OF NEUROLOGY
- Real-Time Trafficking of PEGylated Liposomes in the Rodent Focal Brain Ischemia Analyzed by Positron Emission Tomography
- (2014) Tatsuya Fukuta et al. ARTIFICIAL ORGANS
- RVG-Peptide-Linked Trimethylated Chitosan for Delivery of siRNA to the Brain
- (2014) Yikun Gao et al. BIOMACROMOLECULES
- Paclitaxel loaded liposomes decorated with a multifunctional tandem peptide for glioma targeting
- (2014) Yayuan Liu et al. BIOMATERIALS
- Hypothalamic Tanycytes Are an ERK-Gated Conduit for Leptin into the Brain
- (2014) Eglantine Balland et al. Cell Metabolism
- Bile acids permeabilize the blood brain barrier after bile duct ligation in rats via Rac1-dependent mechanisms
- (2014) Matthew Quinn et al. DIGESTIVE AND LIVER DISEASE
- Cell-Based in Vitro Blood–Brain Barrier Model Can Rapidly Evaluate Nanoparticles’ Brain Permeability in Association with Particle Size and Surface Modification
- (2014) Sanshiro Hanada et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Tissue inhibitor of matrix metalloproteinases-1 loaded poly(lactic-co-glycolic acid) nanoparticles for delivery across the blood–brain barrier
- (2014) Mayank Chaturvedi et al. International Journal of Nanomedicine
- Complement activation-related pseudoallergy: A stress reaction in blood triggered by nanomedicines and biologicals
- (2014) Janos Szebeni MOLECULAR IMMUNOLOGY
- Inhibition of Receptor Signaling and of Glioblastoma-derived Tumor Growth by a Novel PDGFRβ Aptamer
- (2014) Simona Camorani et al. MOLECULAR THERAPY
- Mfsd2a is critical for the formation and function of the blood–brain barrier
- (2014) Ayal Ben-Zvi et al. NATURE
- Plasma phospholipids identify antecedent memory impairment in older adults
- (2014) Mark Mapstone et al. NATURE MEDICINE
- Squalenoyl adenosine nanoparticles provide neuroprotection after stroke and spinal cord injury
- (2014) Alice Gaudin et al. Nature Nanotechnology
- Overcoming the challenges in administering biopharmaceuticals: formulation and delivery strategies
- (2014) Samir Mitragotri et al. NATURE REVIEWS DRUG DISCOVERY
- Incidence of cerebral microbleeds in preclinical Alzheimer disease
- (2014) P. A. Yates et al. NEUROLOGY
- A Randomized Trial of Bevacizumab for Newly Diagnosed Glioblastoma
- (2014) Mark R. Gilbert et al. NEW ENGLAND JOURNAL OF MEDICINE
- Mechanisms of complement activation by dextran-coated superparamagnetic iron oxide (SPIO) nanoworms in mouse versus human serum
- (2014) Nirmal K Banda et al. Particle and Fibre Toxicology
- A Novel Blood-Brain Barrier Co-Culture System for Drug Targeting of Alzheimer’s Disease: Establishment by Using Acitretin as a Model Drug
- (2014) Christian Freese et al. PLoS One
- Instruction of Circulating Endothelial Progenitors In Vitro towards Specialized Blood-Brain Barrier and Arterial Phenotypes
- (2014) Julie Boyer-Di Ponio et al. PLoS One
- A Stable and Reproducible Human Blood-Brain Barrier Model Derived from Hematopoietic Stem Cells
- (2014) Romeo Cecchelli et al. PLoS One
- Brain-Targeted Delivery of Trans-Activating Transcriptor-Conjugated Magnetic PLGA/Lipid Nanoparticles
- (2014) Xiangru Wen et al. PLoS One
- A retinoic acid-enhanced, multicellular human blood-brain barrier model derived from stem cell sources
- (2014) Ethan S. Lippmann et al. Scientific Reports
- Excision of viral reprogramming cassettes by Cre protein transduction enables rapid, robust and efficient derivation of transgene-free human induced pluripotent stem cells
- (2014) Asifiqbal Kadari et al. Stem Cell Research & Therapy
- Alzheimer’s disease drug-development pipeline: few candidates, frequent failures
- (2014) Jeffrey L Cummings et al. Alzheimers Research & Therapy
- The Cerebrovascular Basement Membrane: Role in the Clearance of β-amyloid and Cerebral Amyloid Angiopathy
- (2014) Alan W. J. Morris et al. Frontiers in Aging Neuroscience
- Intravenously Injected Human Apolipoprotein A‐I Rapidly Enters the Central Nervous System via the Choroid Plexus
- (2014) Sophie Stukas et al. Journal of the American Heart Association
- Systemic gene delivery to the central nervous system using Adeno-associated virus
- (2014) Mathieu Bourdenx et al. Frontiers in Molecular Neuroscience
- Selective Nanovector Mediated Treatment of Activated Proinflammatory Microglia/Macrophages in Spinal Cord Injury
- (2013) Simonetta Papa et al. ACS Nano
- Custom Cerium Oxide Nanoparticles Protect against a Free Radical Mediated Autoimmune Degenerative Disease in the Brain
- (2013) Karin L. Heckman et al. ACS Nano
- Endocytotic uptake of iron oxide nanoparticles by cultured brain microglial cells
- (2013) Eva M. Luther et al. Acta Biomaterialia
- Interstitial fluid drainage is impaired in ischemic stroke and Alzheimer’s disease mouse models
- (2013) Michal Arbel-Ornath et al. ACTA NEUROPATHOLOGICA
- Regional differences in the morphological and functional effects of aging on cerebral basement membranes and perivascular drainage of amyloid-β from the mouse brain
- (2013) Cheryl A. Hawkes et al. AGING CELL
- Iron Oxide Magnetic Nanoparticles Highlight Early Involvement of the Choroid Plexus in Central Nervous System Inflammation
- (2013) Jason M. Millward et al. ASN Neuro
- Targeted therapy of brain ischaemia using Fas ligand antibody conjugated PEG-lipid nanoparticles
- (2013) Ying-mei Lu et al. BIOMATERIALS
- A detailed method for preparation of a functional and flexible blood–brain barrier model using porcine brain endothelial cells
- (2013) Adjanie Patabendige et al. BRAIN RESEARCH
- Identification through high-throughput screening of 4'-methoxyflavone and 3',4'-dimethoxyflavone as novel neuroprotective inhibitors of parthanatos
- (2013) A A Fatokun et al. BRITISH JOURNAL OF PHARMACOLOGY
- Original article β-amyloid deposits in veins in patients with cerebral amyloid angiopathy and intracerebral haemorrhage
- (2013) Tadeusz Mendel et al. FOLIA NEUROPATHOLOGICA
- The APOE ε4/ε4 Genotype Potentiates Vascular Fibrin(Ogen) Deposition in Amyloid-Laden Vessels in the Brains of Alzheimer's Disease Patients
- (2013) Karin Hultman et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Tanycyte-like cells form a blood-cerebrospinal fluid barrier in the circumventricular organs of the mouse brain
- (2013) Fanny Langlet et al. JOURNAL OF COMPARATIVE NEUROLOGY
- Complement monitoring of Pluronic 127 gel and micelles: Suppression of copolymer-mediated complement activation by elevated serum levels of HDL, LDL, and apolipoproteins AI and B-100
- (2013) Islam Hamad et al. JOURNAL OF CONTROLLED RELEASE
- Bone marrow uptake of ferumoxytol: A preliminary study in healthy human subjects
- (2013) Pippa Storey et al. JOURNAL OF MAGNETIC RESONANCE IMAGING
- Nanomedicine and the complement paradigm
- (2013) S. Moein Moghimi et al. Nanomedicine-Nanotechnology Biology and Medicine
- Application of a hemolysis assay for analysis of complement activation by perfluorocarbon nanoparticles
- (2013) Christine T.N. Pham et al. Nanomedicine-Nanotechnology Biology and Medicine
- Safety/feasibility of targeting the substantia nigra with AAV2-neurturin in Parkinson patients
- (2013) R. T. Bartus et al. NEUROLOGY
- Angiopep-Conjugated Nanoparticles for Targeted Long-Term Gene Therapy of Parkinson’s Disease
- (2013) Rongqin Huang et al. PHARMACEUTICAL RESEARCH
- Nanoparticle Mediated P-Glycoprotein Silencing for Improved Drug Delivery across the Blood-Brain Barrier: A siRNA-Chitosan Approach
- (2013) Jostein Malmo et al. PLoS One
- Functionalized Carbon Nanotubes in the Brain: Cellular Internalization and Neuroinflammatory Responses
- (2013) Giuseppe Bardi et al. PLoS One
- Transcytosis and brain uptake of transferrin-containing nanoparticles by tuning avidity to transferrin receptor
- (2013) D. T. Wiley et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Non-specific interactions between soluble proteins and lipids induce irreversible changes in the properties of lipid bilayers
- (2013) Francesca Ruggeri et al. Soft Matter
- Pitfalls of assays devoted to evaluation of oxidative stress induced by inorganic nanoparticles
- (2013) Juliana Tournebize et al. TALANTA
- Multicellular Self-Assembled Spheroidal Model of the Blood Brain Barrier
- (2013) Eduard Urich et al. Scientific Reports
- Molecular imaging of drug transit through the blood-brain barrier with MALDI mass spectrometry imaging
- (2013) Xiaohui Liu et al. Scientific Reports
- Pre-existing Anti–Adeno-Associated Virus Antibodies as a Challenge in AAV Gene Therapy
- (2013) Vedell Louis Jeune et al. Human Gene Therapy Methods
- Efficient and Rapid Derivation of Primitive Neural Stem Cells and Generation of Brain Subtype Neurons From Human Pluripotent Stem Cells
- (2013) Yiping Yan et al. Stem Cells Translational Medicine
- Deoxycholic Acid as a Modifier of the Permeation of Gliclazide through the Blood Brain Barrier of a Rat
- (2013) Mladena Lalić-Popović et al. Journal of Diabetes Research
- Relationship Between Cyclophilin A Levels and Matrix Metalloproteinase 9 Activity in Cerebrospinal Fluid of Cognitively Normal Apolipoprotein E4 Carriers and Blood-Brain Barrier Breakdown
- (2013) Matthew R. Halliday et al. JAMA Neurology
- Highly Stabilized Curcumin Nanoparticles Tested in an In Vitro Blood–Brain Barrier Model and in Alzheimer’s Disease Tg2576 Mice
- (2012) Kwok Kin Cheng et al. AAPS Journal
- Modulating Adaptive Immune Responses to Peptide Self-Assemblies
- (2012) Jai S. Rudra et al. ACS Nano
- MTT assay for cell viability: Intracellular localization of the formazan product is in lipid droplets
- (2012) Juan C. Stockert et al. ACTA HISTOCHEMICA
- Effect of Systemic Infection Induced by Pseudomonas aeruginosa on the Brain Uptake of Colistin in Mice
- (2012) Liang Jin et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Gold Nanomaterials: Preparation, Chemical Modification, Biomedical Applications and Potential Risk Assessment
- (2012) Xiu-Mei Jiang et al. APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
- Nanoparticles accumulate in ischemic core and penumbra region even when cerebral perfusion is reduced
- (2012) Takayuki Ishii et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The targeted delivery of anticancer drugs to brain glioma by PEGylated oxidized multi-walled carbon nanotubes modified with angiopep-2
- (2012) Jinfeng Ren et al. BIOMATERIALS
- Deficiency in Mural Vascular Cells Coincides with Blood-Brain Barrier Disruption in Alzheimer's Disease
- (2012) Jesse D. Sengillo et al. BRAIN PATHOLOGY
- Vitamin D-binding protein interacts with Aβ and suppresses Aβ-mediated pathology
- (2012) M Moon et al. CELL DEATH AND DIFFERENTIATION
- Intracerebral CpG Immunotherapy with Carbon Nanotubes Abrogates Growth of Subcutaneous Melanomas in Mice
- (2012) H. Fan et al. CLINICAL CANCER RESEARCH
- AAV2-neurturin (CERE-120) for Parkinson's disease
- (2012) Patrick Hickey et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- Antibodies against polyethylene glycol in healthy subjects and in patients treated with PEG-conjugated agents
- (2012) Ricardo P Garay et al. Expert Opinion on Drug Delivery
- Clinically-translated silica nanoparticles as dual-modality cancer-targeted probes for image-guided surgery and interventions
- (2012) Michelle S. Bradbury et al. Integrative Biology
- A single injection of liposomal asialo-erythropoietin improves motor function deficit caused by cerebral ischemia/reperfusion
- (2012) Takayuki Ishii et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Delivery of paclitaxel across cellular barriers using a dendrimer-based nanocarrier
- (2012) Huey Minn Teow et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Neurological Diseases in Relation to the Blood–Brain Barrier
- (2012) Gary A Rosenberg JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Amelioration of cerebral ischemia–reperfusion injury based on liposomal drug delivery system with asialo-erythropoietin
- (2012) Takayuki Ishii et al. JOURNAL OF CONTROLLED RELEASE
- Characteristics of Aquaporin Expression Surrounding Senile Plaques and Cerebral Amyloid Angiopathy in Alzheimer Disease
- (2012) Akihiko Hoshi et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- A 1-42-RAGE Interaction Disrupts Tight Junctions of the Blood-Brain Barrier Via Ca2+-Calcineurin Signaling
- (2012) S.-Y. Kook et al. JOURNAL OF NEUROSCIENCE
- Functional Imaging of Legumain in Cancer Using a New Quenched Activity-Based Probe
- (2012) Laura E. Edgington et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- The vascular factor in Alzheimer's disease: A study in Golgi technique and electron microscopy
- (2012) Stavros J. Baloyannis et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Derivation of blood-brain barrier endothelial cells from human pluripotent stem cells
- (2012) Ethan S Lippmann et al. NATURE BIOTECHNOLOGY
- Neuroinflammation and Blood-Brain Barrier Changes in Capillary Amyloid Angiopathy
- (2012) Anna Carrano et al. Neurodegenerative Diseases
- Review: Microglia of the aged brain: primed to be activated and resistant to regulation
- (2012) D. M. Norden et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- Selection of DNA Aptamers against Glioblastoma Cells with High Affinity and Specificity
- (2012) Dezhi Kang et al. PLoS One
- A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid
- (2012) J. J. Iliff et al. Science Translational Medicine
- Aptamers and Their Biological Applications
- (2012) Kyung-Mi Song et al. SENSORS
- Negatively Charged Gold Nanoparticles Inhibit Alzheimer's Amyloid-β Fibrillization, Induce Fibril Dissociation, and Mitigate Neurotoxicity
- (2012) Yi-Hung Liao et al. Small
- Four types of inorganic nanoparticles stimulate the inflammatory reaction in brain microglia and damage neurons in vitro
- (2012) Yang Xue et al. TOXICOLOGY LETTERS
- Engineering triiodothyronine (T3) nanoparticle for use in ischemic brain stroke
- (2012) Alexander Mdzinarishvili et al. Drug Delivery and Translational Research
- Vascular β-amyloid and early astrocyte alterations impair cerebrovascular function and cerebral metabolism in transgenic arcAβ mice
- (2011) Mario Merlini et al. ACTA NEUROPATHOLOGICA
- Activation of complement by therapeutic liposomes and other lipid excipient-based therapeutic products: Prediction and prevention
- (2011) Janos Szebeni et al. ADVANCED DRUG DELIVERY REVIEWS
- Material properties in complement activation
- (2011) S. Moein Moghimi et al. ADVANCED DRUG DELIVERY REVIEWS
- Real-Time Imaging of Perivascular Transport of Nanoparticles During Convection-Enhanced Delivery in the Rat Cortex
- (2011) Conor P. Foley et al. ANNALS OF BIOMEDICAL ENGINEERING
- Biodistribution Study of Nanometric Hybrid Gadolinium Oxide Particles as a Multimodal SPECT/MR/Optical Imaging and Theragnostic Agent
- (2011) David Kryza et al. BIOCONJUGATE CHEMISTRY
- New perspective for the treatment of Alzheimer diseases: Liposomal rivastigmine formulations
- (2011) N. Başaran Mutlu et al. DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
- Topiramate Treatment Protects Blood-Brain Barrier Pericytes from Hyperglycemia-Induced Oxidative Damage in Diabetic Mice
- (2011) Tulin O. Price et al. ENDOCRINOLOGY
- Complement activation by polyethoxylated pharmaceutical surfactants: Cremophor-EL, Tween-80 and Tween-20
- (2011) Zsóka Weiszhár et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Lactoferrin conjugated PEG-PLGA nanoparticles for brain delivery: Preparation, characterization and efficacy in Parkinson's disease
- (2011) Kaili Hu et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Odorranalectin-conjugated nanoparticles: Preparation, brain delivery and pharmacodynamic study on Parkinson's disease following intranasal administration
- (2011) Ziyi Wen et al. JOURNAL OF CONTROLLED RELEASE
- Complement system and the brain: Selected pathologies and avenues toward engineering of neurological nanomedicines
- (2011) Barbara Lettiero et al. JOURNAL OF CONTROLLED RELEASE
- Complement in the brain
- (2011) Robert Veerhuis et al. MOLECULAR IMMUNOLOGY
- Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes
- (2011) Lydia Alvarez-Erviti et al. NATURE BIOTECHNOLOGY
- Fabrication Principles and Their Contribution to the Superior In Vivo Therapeutic Efficacy of Nano-Liposomes Remote Loaded with Glucocorticoids
- (2011) Yuval Avnir et al. PLoS One
- The importance of a validated standard methodology to define in vitro toxicity of nano-TiO2
- (2011) Janez Valant et al. PROTOPLASMA
- The Hedgehog Pathway Promotes Blood-Brain Barrier Integrity and CNS Immune Quiescence
- (2011) J. I. Alvarez et al. SCIENCE
- Validation of an LDH assay for assessing nanoparticle toxicity
- (2011) Xianglu Han et al. TOXICOLOGY
- Microglial Response to Gold Nanoparticles
- (2010) Eliza Hutter et al. ACS Nano
- Sensory circumventricular organs in health and disease
- (2010) Sílvia Sisó et al. ACTA NEUROPATHOLOGICA
- Effect of lactoferrin- and transferrin-conjugated polymersomes in brain targeting: in vitro and in vivo evaluations
- (2010) Hui-le Gao et al. ACTA PHARMACOLOGICA SINICA
- A leptin derived 30-amino-acid peptide modified pegylated poly-l-lysine dendrigraft for brain targeted gene delivery
- (2010) Yang Liu et al. BIOMATERIALS
- Lipid-based nanoparticles with high binding affinity for amyloid-β1–42 peptide
- (2010) Marco Gobbi et al. BIOMATERIALS
- Exciting New Advances in Neuro-Oncology: The Avenue to a Cure for Malignant Glioma
- (2010) E. G. Van Meir et al. CA-A CANCER JOURNAL FOR CLINICIANS
- T lymphocyte expression of complement receptor 2 (CR2/CD21): a role in adhesive cell-cell interactions and dysregulation in a patient with systemic lupus erythematosus (SLE)
- (2010) E. LEVY et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- Carbon Nanotubes Enhance CpG Uptake and Potentiate Antiglioma Immunity
- (2010) D. Zhao et al. CLINICAL CANCER RESEARCH
- Curvature of Synthetic and Natural Surfaces Is an Important Target Feature in Classical Pathway Complement Activation
- (2010) Martin Bjerregård Pedersen et al. JOURNAL OF IMMUNOLOGY
- Aquaporin Expression in the Brains of Patients With or Without Cerebral Amyloid Angiopathy
- (2010) Parham Moftakhar et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Age-dependent changes in the structure, composition and biophysical properties of a human basement membrane
- (2010) Joseph Candiello et al. MATRIX BIOLOGY
- Psammoma bodies – Friends or foes of the aging choroid plexus
- (2010) Ivan Jovanović et al. MEDICAL HYPOTHESES
- Complement: a key system for immune surveillance and homeostasis
- (2010) Daniel Ricklin et al. NATURE IMMUNOLOGY
- Neisseria meningitidis Induces Brain Microvascular Endothelial Cell Detachment from the Matrix and Cleavage of Occludin: A Role for MMP-8
- (2010) Alexandra Schubert-Unkmeir et al. PLoS Pathogens
- Blood Interactions with Noble Metals: Coagulation and Immune Complement Activation
- (2009) Mats Hulander et al. ACS Applied Materials & Interfaces
- The effects of blood–brain barrier disruption on glial cell function in multiple sclerosis: Figure 1
- (2009) Stephen McQuaid et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Immunocompatibility properties of lipid–polymer hybrid nanoparticles with heterogeneous surface functional groups
- (2009) Carolina Salvador-Morales et al. BIOMATERIALS
- Post-ischemic hypothermia attenuates loss of the vascular basement membrane proteins, agrin and SPARC, and the blood–brain barrier disruption after global cerebral ischemia
- (2009) Ewa Baumann et al. BRAIN RESEARCH
- Molecular mechanisms of late apoptotic/necrotic cell clearance
- (2009) I K H Poon et al. CELL DEATH AND DIFFERENTIATION
- Assessing cytotoxicity of (iron oxide-based) nanoparticles: an overview of different methods exemplified with cationic magnetoliposomes
- (2009) Stefaan J. H. Soenen et al. Contrast Media & Molecular Imaging
- Differential distribution of tight junction proteins suggests a role for tanycytes in blood-hypothalamus barrier regulation in the adult mouse brain
- (2009) Amandine Mullier et al. JOURNAL OF COMPARATIVE NEUROLOGY
- Albumin nanoparticles targeted with Apo E enter the CNS by transcytosis and are delivered to neurones
- (2009) Anja Zensi et al. JOURNAL OF CONTROLLED RELEASE
- Neuroprotection in a 6-hydroxydopamine-lesioned Parkinson model using lactoferrin-modified nanoparticles
- (2009) Rongqin Huang et al. JOURNAL OF GENE MEDICINE
- Pegylated nanoliposomes remote-loaded with the antioxidant tempamine ameliorate experimental autoimmune encephalomyelitis
- (2009) Pablo Kizelsztein et al. JOURNAL OF NEUROIMMUNOLOGY
- A Nanomedicine Transports a Peptide Caspase-3 Inhibitor across the Blood-Brain Barrier and Provides Neuroprotection
- (2009) H. Karatas et al. JOURNAL OF NEUROSCIENCE
- Gene therapy using lactoferrin-modified nanoparticles in a rotenone-induced chronic Parkinson model
- (2009) Rongqin Huang et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Molecular signatures of disease brain endothelia provide new sites for CNS-directed enzyme therapy
- (2009) Yong Hong Chen et al. NATURE MEDICINE
- Self-assembled cationic peptide nanoparticles as an efficient antimicrobial agent
- (2009) Lihong Liu et al. Nature Nanotechnology
- DNA aptamer-micelle as an efficient detection/delivery vehicle toward cancer cells
- (2009) Y. Wu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The role of nanoparticle size in hemocompatibility
- (2009) Andrea Mayer et al. TOXICOLOGY
- CSF Multianalyte Profile Distinguishes Alzheimer and Parkinson Diseases
- (2008) Jing Zhang et al. AMERICAN JOURNAL OF CLINICAL PATHOLOGY
- Apolipoproteins inhibit the innate immunity activated by necrotic cells or bacterial endotoxin
- (2008) Nam-Hyuk Cho et al. IMMUNOLOGY
- Brain and muscle of Wistar rats are the main targets of intravenous dendrimeric sulfadiazine
- (2008) M.J. Prieto et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- A leaky blood-brain barrier, fibrinogen infiltration and microglial reactivity in inflamed Alzheimer’s disease brain
- (2008) Jae K. Ryu et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Ultrastructural and temporal changes of the microvascular basement membrane and astrocyte interface following focal cerebral ischemia
- (2008) Il Kwon et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Complement activation by PEGylated single-walled carbon nanotubes is independent of C1q and alternative pathway turnover
- (2008) Islam Hamad et al. MOLECULAR IMMUNOLOGY
- Preclinical Studies To Understand Nanoparticle Interaction with the Immune System and Its Potential Effects on Nanoparticle Biodistribution
- (2008) Marina A. Dobrovolskaia et al. MOLECULAR PHARMACEUTICS
- Interaction of colloidal gold nanoparticles with human blood: effects on particle size and analysis of plasma protein binding profiles
- (2008) Marina A. Dobrovolskaia et al. Nanomedicine-Nanotechnology Biology and Medicine
- ALS-causing SOD1 mutants generate vascular changes prior to motor neuron degeneration
- (2008) Zhihui Zhong et al. NATURE NEUROSCIENCE
- Aptamer-based endocytosis of a lysosomal enzyme
- (2008) C.-h. B. Chen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- MMP-9–Positive Neutrophil Infiltration Is Associated to Blood–Brain Barrier Breakdown and Basal Lamina Type IV Collagen Degradation During Hemorrhagic Transformation After Human Ischemic Stroke
- (2008) Anna Rosell et al. STROKE
- An in vitro blood-brain barrier model for high throughput (HTS) toxicological screening
- (2008) Maxime Culot et al. TOXICOLOGY IN VITRO
- Complement activation on surfaces carrying amino groups
- (2007) Mitsuaki Toda et al. BIOMATERIALS
- Hypertensive encephalopathy and the blood-brain barrier: is δPKC a gatekeeper?
- (2007) Wen-Hai Chou et al. JOURNAL OF CLINICAL INVESTIGATION
- Blood–brain barrier: Ageing and microvascular disease – systematic review and meta-analysis
- (2007) Andrew J. Farrall et al. NEUROBIOLOGY OF AGING
- Restricted transport of anti-transferrin receptor antibody (OX26) through the blood-brain barrier in the rat
- (2003) Torben Moos et al. JOURNAL OF NEUROCHEMISTRY
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