标题
The emerging role of the KCTD proteins in cancer
作者
关键词
-
出版物
Cell Communication and Signaling
Volume 19, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2021-05-17
DOI
10.1186/s12964-021-00737-8
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Targeting Natural Killer Cells for Tumor Immunotherapy
- (2020) Cai Zhang et al. Frontiers in Immunology
- Tumor necrosis factor α-induced protein 1 as a novel tumor suppressor through selective downregulation of CSNK2B blocks nuclear factor-κB activation in hepatocellular carcinoma
- (2020) Ye Xiao et al. EBioMedicine
- Validation of Novel Prognostic Biomarkers for Early-Stage Clear-Cell, Endometrioid and Mucinous Ovarian Carcinomas Using Immunohistochemistry
- (2020) Hanna Engqvist et al. Frontiers in Oncology
- KCTD5, a novel TRPM4‐regulatory protein required for cell migration as a new predictor for breast cancer prognosis
- (2020) José Rivas et al. FASEB JOURNAL
- KCTD12 promotes G1/S transition of breast cancer cell through activating the AKT/FOXO1 signaling
- (2020) Run-yi Ye et al. JOURNAL OF CLINICAL LABORATORY ANALYSIS
- Depletion of Trichoplein (TpMs) Causes Chromosome Mis-Segregation, DNA Damage and Chromosome Instability in Cancer Cells
- (2020) Angela Lauriola et al. Cancers
- Active RAC1 Promotes Tumorigenic Phenotypes and Therapy Resistance in Solid Tumors
- (2020) Pradip De et al. Cancers
- KCTD15 Protein Expression in Peripheral Blood and Acute Myeloid Leukemia
- (2020) Giovanni Smaldone et al. Diagnostics
- K+ Channel Tetramerization Domain 5 (KCTD5) Protein Regulates Cell Migration, Focal Adhesion Dynamics and Spreading through Modulation of Ca2+ Signaling and Rac1 Activity
- (2020) Jimena Canales et al. Cells
- Regulation of purine metabolism connects KCTD13 to a metabolic disorder with autistic features
- (2020) Jon M. Madison et al. iScience
- Structural basis for KCTD-mediated rapid desensitization of GABAB signalling
- (2019) Sanduo Zheng et al. NATURE
- The TGFβ-miR-499a-SHKBP1 pathway induces resistance to EGFR inhibitors in osteosarcoma cancer stem cell-like cells
- (2019) Tian Wang et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Induction of tumor suppressor KCTD11 during periovulatory period in rat ovary
- (2019) Yu Liu et al. Reproductive Biology
- GENT2: an updated gene expression database for normal and tumor tissues
- (2019) Seung-Jin Park et al. BMC Medical Genomics
- Adefovir dipivoxil sensitizes colon cancer cells to vemurafenib by disrupting the KCTD12-CDK1 interaction
- (2019) Jie Yang et al. CANCER LETTERS
- KCTD : A new gene family involved in neurodevelopmental and neuropsychiatric disorders
- (2019) Xinchen Teng et al. CNS Neuroscience & Therapeutics
- Cullin-3/KCTD10 complex is essential for K27-polyubiquitination of EIF3D in human hepatocellular carcinoma HepG2 cells
- (2019) Masashi Maekawa et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Wnt, Notch, and TGF-β Pathways Impinge on Hedgehog Signaling Complexity: An Open Window on Cancer
- (2019) Maria Pelullo et al. Frontiers in Genetics
- Role of alternative splicing signatures in the prognosis of glioblastoma
- (2019) Zu‐cheng Xie et al. Cancer Medicine
- KCTD15 inhibits the Hedgehog pathway in Medulloblastoma cells by increasing protein levels of the oncosuppressor KCASH2
- (2019) Eleonora Spiombi et al. Oncogenesis
- Phenotypic characterization of KCTD3 -related developmental epileptic encephalopathy
- (2018) E.A. Faqeih et al. CLINICAL GENETICS
- The essential player in adipogenesis GRP78 is a novel KCTD15 interactor
- (2018) Giovanni Smaldone et al. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
- The Cullin-3–Rbx1–KCTD10 complex controls endothelial barrier function via K63 ubiquitination of RhoB
- (2018) Igor Kovačević et al. JOURNAL OF CELL BIOLOGY
- Role of differentially expressed genes and long non-coding RNAs in papillary thyroid carcinoma diagnosis, progression, and prognosis
- (2018) Wei-Yang Cai et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Contribution of KCTD12 to esophageal squamous cell carcinoma
- (2018) Mohammad Reza Abbaszadegan et al. BMC CANCER
- The regulation of cilium assembly and disassembly in development and disease
- (2018) Lei Wang et al. DEVELOPMENT
- Cullin-3/KCTD10 E3 complex is essential for Rac1 activation through RhoB degradation in human epidermal growth factor receptor 2-positive breast cancer cells
- (2018) Akari Murakami et al. CANCER SCIENCE
- Cullin-3–KCTD10-mediated CEP97 degradation promotes primary cilium formation
- (2018) Tomoaki Nagai et al. JOURNAL OF CELL SCIENCE
- COSMIC: the Catalogue Of Somatic Mutations In Cancer
- (2018) John G Tate et al. NUCLEIC ACIDS RESEARCH
- Identification of novel therapeutic target genes and pathway in pancreatic cancer by integrative analysis
- (2017) Bangli Hu et al. MEDICINE
- Kctd20 promotes the development of non-small cell lung cancer through activating Fak/AKT pathway and predicts poor overall survival of patients
- (2017) Xiupeng Zhang et al. MOLECULAR CARCINOGENESIS
- Genetic wiring maps of single-cell protein states reveal an off-switch for GPCR signalling
- (2017) Markus Brockmann et al. NATURE
- Kctd13 deletion reduces synaptic transmission via increased RhoA
- (2017) Christine Ochoa Escamilla et al. NATURE
- KCTD12 promotes tumorigenesis by facilitating CDC25B/CDK1/Aurora A-dependent G2/M transition
- (2017) Y Zhong et al. ONCOGENE
- KCTD11 inhibits growth and metastasis of hepatocellular carcinoma through activating Hippo signaling
- (2017) Rongliang Tong et al. Oncotarget
- Influence of TFAP2B and KCTD15 genetic variability on personality dimensions in anorexia and bulimia nervosa
- (2017) Carmen Gamero-Villarroel et al. Brain and Behavior
- Non-canonical GLI1/2 activation by PI3K/AKT signaling in renal cell carcinoma: A novel potential therapeutic target
- (2016) Jiancheng Zhou et al. CANCER LETTERS
- Caudatin targets TNFAIP1/NF-κB and cytochrome c/caspase signaling to suppress tumor progression in human uterine cancer
- (2016) Zhi-Wen Tan et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Ndel1 suppresses ciliogenesis in proliferating cells by regulating the trichoplein–Aurora A pathway
- (2016) Hironori Inaba et al. JOURNAL OF CELL BIOLOGY
- The centrosomal Deubiquitylase USP21 regulates Gli1 transcriptional activity and stability.
- (2016) Claire Heride et al. JOURNAL OF CELL SCIENCE
- Structural Insights into KCTD Protein Assembly and Cullin3 Recognition
- (2016) Alan X. Ji et al. JOURNAL OF MOLECULAR BIOLOGY
- Lentiviral-mediated overexpression of KCTD12 inhibits the proliferation of human uveal melanoma OCM-1 cells
- (2016) Lifu Luo et al. ONCOLOGY REPORTS
- MEG3, HCN3 and linc01105 influence the proliferation and apoptosis of neuroblastoma cells via the HIF-1α and p53 pathways
- (2016) Weitao Tang et al. Scientific Reports
- KCTD12 Regulates Colorectal Cancer Cell Stemness through the ERK Pathway
- (2016) Liping Li et al. Scientific Reports
- Interactions of cullin3/KCTD5 complexes with both cytoplasmic and nuclear proteins: Evidence for a role in protein stabilization
- (2015) Natalja Rutz et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Novel genetic causes for cerebral visual impairment
- (2015) Daniëlle GM Bosch et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Interaction between microRNA-181a and TNFAIP1 regulates pancreatic cancer proliferation and migration
- (2015) Peng Zhang et al. TUMOR BIOLOGY
- MicroRNA-224 is implicated in lung cancer pathogenesis through targeting caspase-3 and caspase-7
- (2015) Ri Cui et al. Oncotarget
- Cullin 3 Recognition Is Not a Universal Property among KCTD Proteins
- (2015) Giovanni Smaldone et al. PLoS One
- Identification and Characterization of KCASH2 and KCASH3, 2 Novel Cullin3 Adaptors Suppressing Histone Deacetylase and Hedgehog Activity in Medulloblastoma
- (2015) Enrico De Smaele et al. NEOPLASIA
- KCTD10 is critical for heart and blood vessel development of zebrafish
- (2014) X. Hu et al. ACTA BIOCHIMICA ET BIOPHYSICA SINICA
- Molecular recognition of Cullin3 by KCTDs: Insights from experimental and computational investigations
- (2014) Nicole Balasco et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- Knockdown of TNFAIP1 inhibits growth and induces apoptosis in osteosarcoma cells through inhibition of the nuclear factor-κB pathway
- (2014) CHENG-LIN ZHANG et al. ONCOLOGY REPORTS
- KCTD1 Suppresses Canonical Wnt Signaling Pathway by Enhancing β-catenin Degradation
- (2014) Xinxin Li et al. PLoS One
- KCTD10 Is Involved in the Cardiovascular System and Notch Signaling during Early Embryonic Development
- (2014) Kaiqun Ren et al. PLoS One
- The genetics of human obesity
- (2014) Jill Waalen Translational Research
- Ubiquitin-proteasome system controls ciliogenesis at the initial step of axoneme extension
- (2014) Kousuke Kasahara et al. Nature Communications
- KCTD11Tumor Suppressor Gene Expression Is Reduced in Prostate Adenocarcinoma
- (2014) Francesca Zazzeroni et al. Biomed Research International
- Mutations in KCTD1 Cause Scalp-Ear-Nipple Syndrome
- (2013) Alexander G. Marneros et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Protein partners of KCTD proteins provide insights about their functional roles in cell differentiation and vertebrate development
- (2013) Mikhail Skoblov et al. BIOESSAYS
- KCTD20, a relative of BTBD10, is a positive regulator of Akt
- (2013) Mikiro Nawa et al. BMC BIOCHEMISTRY
- Hedgehog Signaling Pathway in Ovarian Cancer
- (2013) Joanna Szkandera et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Up-regulation of GABABReceptor Signaling by Constitutive Assembly with the K+Channel Tetramerization Domain-containing Protein 12 (KCTD12)
- (2013) Klara Ivankova et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Up-regulation of Hyperpolarization-activated Cyclic Nucleotide-gated Channel 3 (HCN3) by Specific Interaction with K+Channel Tetramerization Domain-containing Protein 3 (KCTD3)
- (2013) Xiaochun Cao-Ehlker et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The role ofATMmutations and 11q deletions in disease progression in chronic lymphocytic leukemia
- (2013) Tatjana Stankovic et al. LEUKEMIA & LYMPHOMA
- Role of tumor necrosis factor alpha-induced protein 1 in paclitaxel resistance
- (2013) Y Zhu et al. ONCOGENE
- Gene Expression Network Analysis of ETV1 Reveals KCTD10 as a Novel Prognostic Biomarker in Gastrointestinal Stromal Tumor
- (2013) Daisuke Kubota et al. PLoS One
- Identification of Candidate Serum Proteins for Classifying Well-Differentiated Small Intestinal Neuroendocrine Tumors
- (2013) Spyros Darmanis et al. PLoS One
- MicroRNA-373 is upregulated and targets TNFAIP1 in human gastric cancer, contributing to tumorigenesis
- (2013) XIAOTING ZHANG et al. Oncology Letters
- The KCTD family of proteins: structure, function, disease relevance
- (2013) Zhepeng Liu et al. Cell and Bioscience
- Thermal and Chemical Stability of Two Homologous POZ/BTB Domains of KCTD Proteins Characterized by a Different Oligomeric Organization
- (2013) Luciano Pirone et al. Biomed Research International
- Genome-wide methylation screen in low-grade breast cancer identifies novel epigenetically altered genes as potential biomarkers for tumor diagnosis
- (2012) Marta Faryna et al. FASEB JOURNAL
- microRNA-372 maintains oncogene characteristics by targeting TNFAIP1 and affects NFκB signaling in human gastric carcinoma cells
- (2012) CHANG ZHOU et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Fine-Mapping of Restless Legs Locus 4 (RLS4) Identifies a Haplotype over the SPATS2L and KCTD18 Genes
- (2012) Irene Pichler et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- TNFAIP1 interacts with KCTD10 to promote the degradation of KCTD10 proteins and inhibit the transcriptional activities of NF-κB and AP-1
- (2012) Xiang Hu et al. MOLECULAR BIOLOGY REPORTS
- KCTD13 is a major driver of mirrored neuroanatomical phenotypes of the 16p11.2 copy number variant
- (2012) Christelle Golzio et al. NATURE
- Molecular subgroups of medulloblastoma: the current consensus
- (2011) Michael D. Taylor et al. ACTA NEUROPATHOLOGICA
- SH3KBP1-binding protein 1 prevents epidermal growth factor receptor degradation by the interruption of c-Cbl-CIN85 complex
- (2011) Lifeng Feng et al. CELL BIOCHEMISTRY AND FUNCTION
- Association of genetic variants for susceptibility to obesity with type 2 diabetes in Japanese individuals
- (2011) F. Takeuchi et al. DIABETOLOGIA
- Overexpression of S100B, TM4SF4, and OLFM4 Genes Is Correlated with Liver Metastasis in Taiwanese Colorectal Cancer Patients
- (2011) Ming-Yii Huang et al. DNA AND CELL BIOLOGY
- Identification of recurring tumor-specific somatic mutations in acute myeloid leukemia by transcriptome sequencing
- (2011) P A Greif et al. LEUKEMIA
- Progressive Myoclonic Epilepsy-Associated Gene KCTD7 is a Regulator of Potassium Conductance in Neurons
- (2011) Régis Azizieh et al. MOLECULAR NEUROBIOLOGY
- Complex sense-antisense architecture of TNFAIP1/POLDIP2 on 17q11.2 represents a novel transcriptional structural-functional gene module involved in breast cancer progression
- (2010) Oleg V Grinchuk et al. BMC GENOMICS
- The tumor suppressor gene KCTD11REN is regulated by Sp1 and methylation and its expression is reduced in tumors
- (2010) M Michela Mancarelli et al. Molecular Cancer
- Histone deacetylase and Cullin3–RENKCTD11 ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation
- (2010) Gianluca Canettieri et al. NATURE CELL BIOLOGY
- Pro-apoptotic and antiproliferative activity of human KCNRG, a putative tumor suppressor in 13q14 region
- (2010) Aybike Birerdinc et al. TUMOR BIOLOGY
- Genetic Markers of Adult Obesity Risk Are Associated with Greater Early Infancy Weight Gain and Growth
- (2010) Cathy E. Elks et al. PLOS MEDICINE
- Replication and extension of genome-wide association study results for obesity in 4923 adults from northern Sweden
- (2009) Frida Renström et al. HUMAN MOLECULAR GENETICS
- RhoB induces apoptosisviadirect interaction with TNFAIP1 in HeLa cells
- (2009) Dong-Myung Kim et al. INTERNATIONAL JOURNAL OF CANCER
- KCTD10 interacts with proliferating cell nuclear antigen and its down-regulation could inhibit cell proliferation
- (2009) Yibo Wang et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- The interaction of KCTD1 with transcription factor AP-2α inhibits its transactivation
- (2009) Xiaofeng Ding et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Pentameric Assembly of Potassium Channel Tetramerization Domain-Containing Protein 5
- (2009) Irina S. Dementieva et al. JOURNAL OF MOLECULAR BIOLOGY
- Adenylosuccinate synthetase 1 gene is a novel target of deletion in lung adenocarcinoma
- (2009) Joshua C. Miller et al. MOLECULAR CARCINOGENESIS
- COSMIC (the Catalogue of Somatic Mutations in Cancer): a resource to investigate acquired mutations in human cancer
- (2009) Simon A. Forbes et al. NUCLEIC ACIDS RESEARCH
- Cell Cycle-Dependent Ciliogenesis and Cancer
- (2008) O. V. Plotnikova et al. CANCER RESEARCH
- Pfetin as a Prognostic Biomarker of Gastrointestinal Stromal Tumors Revealed by Proteomics
- (2008) Y. Suehara et al. CLINICAL CANCER RESEARCH
- Characterization and Expression of a Human KCTD1 Gene Containing the BTB Domain, Which Mediates Transcriptional Repression and Homomeric Interactions
- (2008) Xiao-Feng Ding et al. DNA AND CELL BIOLOGY
- Six new loci associated with body mass index highlight a neuronal influence on body weight regulation
- (2008) Cristen J Willer et al. NATURE GENETICS
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started