Interplay between tumor microenvironment and partial EMT as the driver of tumor progression
出版年份 2021 全文链接
标题
Interplay between tumor microenvironment and partial EMT as the driver of tumor progression
作者
关键词
-
出版物
iScience
Volume 24, Issue 2, Pages 102113
出版商
Elsevier BV
发表日期
2021-01-29
DOI
10.1016/j.isci.2021.102113
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Inflammatory breast cancer cells are characterized by abrogated TGFβ1-dependent cell motility and SMAD3 activity
- (2020) Charlotte Rypens et al. BREAST CANCER RESEARCH AND TREATMENT
- A mechanism for epithelial-mesenchymal heterogeneity in a population of cancer cells
- (2020) Shubham Tripathi et al. PLoS Computational Biology
- Guidelines and definitions for research on epithelial–mesenchymal transition
- (2020) Jing Yang et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- A plausible accelerating function of intermediate states in cancer metastasis
- (2020) Hanah Goetz et al. PLoS Computational Biology
- Phenotypic Heterogeneity and Plasticity of Cancer Cell Migration in a Pancreatic Tumor Three-Dimensional Culture Model
- (2020) Seul-Ki Kim et al. Cancers
- Integrative Analysis of Breast Cancer Cells Reveals an Epithelial-Mesenchymal Transition Role in Adaptation to Acidic Microenvironment
- (2020) Mehdi Sadeghi et al. Frontiers in Oncology
- Comparative Study of Transcriptomics-Based Scoring Metrics for the Epithelial-Hybrid-Mesenchymal Spectrum
- (2020) Priyanka Chakraborty et al. Frontiers in Bioengineering and Biotechnology
- CD147 promotes collective invasion through cathepsin B in hepatocellular carcinoma
- (2020) Shi-Jie Wang et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Regulation of heterogeneous cancer-associated fibroblasts: the molecular pathology of activated signaling pathways
- (2020) Go J. Yoshida JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- New Insights Into the Role of Phenotypic Plasticity and EMT in Driving Cancer Progression
- (2020) Sugandha Bhatia et al. Frontiers in Molecular Biosciences
- Three dimensional engineered models to study hypoxia biology in breast cancer
- (2020) Vaishali Aggarwal et al. CANCER LETTERS
- Computational Modeling of the Crosstalk Between Macrophage Polarization and Tumor Cell Plasticity in the Tumor Microenvironment
- (2019) Xuefei Li et al. Frontiers in Oncology
- An FBXW7-ZEB2 axis links EMT and tumour microenvironment to promote colorectal cancer stem cells and chemoresistance
- (2019) Ningning Li et al. Oncogenesis
- ERK2 regulates epithelial-to-mesenchymal plasticity through DOCK10-dependent Rac1/FoxO1 activation
- (2019) Sejeong Shin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Targeting the temporal dynamics of hypoxia-induced tumor-secreted factors halts tumor migration
- (2019) Manjulata Singh et al. CANCER RESEARCH
- Activated Fibroblast Program Orchestrates Tumor Initiation and Progression; Molecular Mechanisms and the Associated Therapeutic Strategies
- (2019) Go J. Yoshida et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Supracellular migration – beyond collective cell migration
- (2019) Adam Shellard et al. JOURNAL OF CELL SCIENCE
- Context-dependent EMT programs in cancer metastasis
- (2019) Nicole M. Aiello et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Quantifying Cancer Epithelial-Mesenchymal Plasticity and its Association with Stemness and Immune Response
- (2019) Dongya Jia et al. Journal of Clinical Medicine
- What makes cells move: Requirements and obstacles for leader cells in collective invasion
- (2019) Bing-jun Chen et al. EXPERIMENTAL CELL RESEARCH
- TGF-β-Mediated Epithelial-Mesenchymal Transition and Cancer Metastasis
- (2019) Yang Hao et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Joint detection of claudin‐1 and junctional adhesion molecule‐A as a therapeutic target in oral epithelial dysplasia and oral squamous cell carcinoma
- (2019) Puja Upadhaya et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Tumor-associated macrophages in tumor metastasis: biological roles and clinical therapeutic applications
- (2019) Yuxin Lin et al. Journal of Hematology & Oncology
- Metabolic Plasticity and Epithelial-Mesenchymal Transition
- (2019) Timothy M. Thomson et al. Journal of Clinical Medicine
- A biophysical model uncovers the size distribution of migrating cell clusters across cancer types
- (2019) Federico Bocci et al. CANCER RESEARCH
- Genetic heterogeneity within collective invasion packs drives leader and follower cell phenotypes
- (2019) Elizabeth L. Zoeller et al. JOURNAL OF CELL SCIENCE
- Inducible formation of leader cells driven by CD44 switching gives rise to collective invasion and metastases in luminal breast carcinomas
- (2019) Cuixia Yang et al. ONCOGENE
- Cell Heterogeneity and Phenotypic Plasticity in Metastasis Formation: The Case of Colon Cancer
- (2019) Miriam Teeuwssen et al. Cancers
- Mechanisms of 3D cell migration
- (2019) Kenneth M. Yamada et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Mapping lung cancer epithelial-mesenchymal transition states and trajectories with single-cell resolution
- (2019) Loukia G. Karacosta et al. Nature Communications
- Three-dimensional cell culture systems as an in vitro platform for cancer and stem cell modeling
- (2019) Nipha Chaicharoenaudomrung et al. World Journal of Stem Cells
- Bulk tumour cell migration in lung carcinomas might be more common than epithelial-mesenchymal transition and be differently regulated
- (2018) Martin Zacharias et al. BMC CANCER
- Epithelial Paradox: Clinical Significance of Coexpression of E-cadherin and Vimentin With Regard to Invasion and Metastasis of Breast Cancer
- (2018) Nami Yamashita et al. Clinical Breast Cancer
- Antibody-based cell-surface proteome profiling of metastatic breast cancer primary explants and cell lines
- (2018) Vera S. Donnenberg et al. CYTOMETRY PART A
- EMT Subtype Influences Epithelial Plasticity and Mode of Cell Migration
- (2018) Nicole M. Aiello et al. DEVELOPMENTAL CELL
- A fixed partial epithelial-mesenchymal transition (EMT) triggers carcinogenesis, whereas asymmetrical division of hybrid EMT cells drives cancer progression
- (2018) Evgeny V. Denisov et al. HEPATOLOGY
- Identification of biomarkers associated with partial epithelial to mesenchymal transition in the secretome of slug over-expressing hepatocellular carcinoma cells
- (2018) Oğuzhan Karaosmanoğlu et al. CELLULAR ONCOLOGY
- Macrophage inflammatory factors promote epithelial-mesenchymal transition in breast cancer
- (2018) Robert B. Bednarczyk et al. Oncotarget
- Shift from stochastic to spatially-ordered expression of serine-glycine synthesis enzymes in 3D microtumors
- (2018) Manjulata Singh et al. Scientific Reports
- Elucidating the Metabolic Plasticity of Cancer: Mitochondrial Reprogramming and Hybrid Metabolic States
- (2018) Dongya Jia et al. Cells
- Dual reporter genetic mouse models of pancreatic cancer identify an epithelial‐to‐mesenchymal transition‐independent metastasis program
- (2018) Yang Chen et al. EMBO Molecular Medicine
- Identification of the tumour transition states occurring during EMT
- (2018) Ievgenia Pastushenko et al. NATURE
- A molecular portrait of epithelial–mesenchymal plasticity in prostate cancer associated with clinical outcome
- (2018) Nataly Stylianou et al. ONCOGENE
- Cancer cell plasticity: Impact on tumor progression and therapy response
- (2018) Victoria da Silva-Diz et al. SEMINARS IN CANCER BIOLOGY
- Epithelial-to-mesenchymal transition in cancer: complexity and opportunities
- (2018) Yun Zhang et al. Frontiers of Medicine
- Phenotypic Plasticity: Driver of Cancer Initiation, Progression, and Therapy Resistance
- (2018) Piyush B. Gupta et al. Cell Stem Cell
- A Novel 3-Dimensional Co-culture Method Reveals a Partial Mesenchymal to Epithelial Transition in Breast Cancer Cells Induced by Adipocytes
- (2018) Nikitha K. Pallegar et al. JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA
- Circulating tumor cells with stemness and epithelial-to-mesenchymal transition features are chemoresistant and predictive of poor outcome in metastatic breast cancer
- (2018) Maria A Papadaki et al. MOLECULAR CANCER THERAPEUTICS
- New insights into the mechanisms of epithelial–mesenchymal transition and implications for cancer
- (2018) Anushka Dongre et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Toward understanding cancer stem cell heterogeneity in the tumor microenvironment
- (2018) Federico Bocci et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Supracellular contraction at the rear of neural crest cell groups drives collective chemotaxis
- (2018) Adam Shellard et al. SCIENCE
- The role of epithelial-mesenchymal transition drivers ZEB1 and ZEB2 in mediating docetaxel-resistant prostate cancer
- (2017) Karen Hanrahan et al. Molecular Oncology
- EMT, CSCs, and drug resistance: the mechanistic link and clinical implications
- (2017) Tsukasa Shibue et al. Nature Reviews Clinical Oncology
- Divide or Conquer: Cell Cycle Regulation of Invasive Behavior
- (2017) Abraham Q. Kohrman et al. TRENDS IN CELL BIOLOGY
- Making Heads or Tails of It: Cell–Cell Adhesion in Cellular and Supracellular Polarity in Collective Migration
- (2017) Jan-Hendrik Venhuizen et al. Cold Spring Harbor Perspectives in Biology
- Tuning Collective Cell Migration by Cell–Cell Junction Regulation
- (2017) Peter Friedl et al. Cold Spring Harbor Perspectives in Biology
- Cellular events and behaviors after grafting of stratified squamous epithelial cell sheet onto a hydrated collagen gel
- (2017) Yoshiyuki Kasai et al. FEBS Open Bio
- Controlled Three-Dimensional Tumor Microenvironments Recapitulate Phenotypic Features and Differential Drug Response in Early vs Advanced Stage Breast Cancer
- (2017) Manjulata Singh et al. ACS Biomaterials-Science & Engineering
- PD-L1 and epithelial-mesenchymal transition in circulating tumor cells from non-small cell lung cancer patients: A molecular shield to evade immune system?
- (2017) Cristina Raimondi et al. OncoImmunology
- Controlled Three-Dimensional Tumor Microenvironments Recapitulate Phenotypic Features and Differential Drug Response in Early vs Advanced Stage Breast Cancer
- (2017) Manjulata Singh et al. ACS Biomaterials Science & Engineering
- Vimentin regulates differentiation switch via modulation of keratin 14 levels and their expression together correlates with poor prognosis in oral cancer patients
- (2017) Crismita Dmello et al. PLoS One
- Three-dimensional spheroid culture targeting versatile tissue bioassays using a PDMS-based hanging drop array
- (2017) Ching-Te Kuo et al. Scientific Reports
- Hypoxic tumor microenvironment: Opportunities to develop targeted therapies
- (2016) Akhil Patel et al. BIOTECHNOLOGY ADVANCES
- Three-Dimensional Breast Cancer Models Mimic Hallmarks of Size-Induced Tumor Progression
- (2016) Manjulata Singh et al. CANCER RESEARCH
- Rab11 collaborates E-cadherin to promote collective cell migration and indicates a poor prognosis in colorectal carcinoma
- (2016) Yuan-Chiang Chung et al. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
- Prometastatic mechanisms of CAF-mediated EMT regulation in pancreatic cancer cells
- (2016) Tao Shan et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Hypoxia and Transforming Growth Factor β Cooperate to Induce Fibulin-5 Expression in Pancreatic Cancer
- (2016) Mary Topalovski et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Myosin II governs collective cell migration behaviour downstream of guidance receptor signalling
- (2016) Anne Combedazou et al. JOURNAL OF CELL SCIENCE
- Collective migration and cell jamming in asthma, cancer and development
- (2016) Jin-Ah Park et al. JOURNAL OF CELL SCIENCE
- A 3D in vitro model to explore the inter-conversion between epithelial and mesenchymal states during EMT and its reversion
- (2016) S. J. Bidarra et al. Scientific Reports
- Production of Uniform 3D Microtumors in Hydrogel Microwell Arrays for Measurement of Viability, Morphology, and Signaling Pathway Activation
- (2015) Manjulata Singh et al. ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES
- Molecular Portraits of Epithelial, Mesenchymal, and Hybrid States in Lung Adenocarcinoma and Their Relevance to Survival
- (2015) M. J. Schliekelman et al. CANCER RESEARCH
- Stem cell state and the epithelial-to-mesenchymal transition: Implications for cancer therapy
- (2015) Vera S. Donnenberg et al. JOURNAL OF CLINICAL PHARMACOLOGY
- Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance
- (2015) Kari R. Fischer et al. NATURE
- Obesity-dependent changes in interstitial ECM mechanics promote breast tumorigenesis
- (2015) Bo Ri Seo et al. Science Translational Medicine
- Epithelial–Mesenchymal Plasticity: A Central Regulator of Cancer Progression
- (2015) Xin Ye et al. TRENDS IN CELL BIOLOGY
- Morphological and immunohistochemical identification of epithelial-to-mesenchymal transition in clinical prostate cancer
- (2015) Kimberley Kolijn et al. Oncotarget
- A spatiotemporally defined in vitro microenvironment for controllable signal delivery and drug screening
- (2014) Ching-Te Kuo et al. ANALYST
- TGF-β isoforms induce EMT independent migration of ovarian cancer cells
- (2014) Jingfang Gao et al. Cancer Cell International
- Invading cancer cells are predominantly in G0/G1resulting in chemoresistance demonstrated by real-time FUCCI imaging
- (2014) Shuya Yano et al. CELL CYCLE
- Increased Expression of EIF5A2, Via Hypoxia or Gene Amplification, Contributes to Metastasis and Angiogenesis of Esophageal Squamous Cell Carcinoma
- (2014) Yan Li et al. GASTROENTEROLOGY
- Cancer cell invasion and EMT marker expression: a three-dimensional study of the human cancer-host interface
- (2014) P Bronsert et al. JOURNAL OF PATHOLOGY
- Cutaneous carcinosarcoma: further insights into its mutational landscape through massive parallel genome sequencing
- (2014) Alberto Paniz-Mondolfi et al. VIRCHOWS ARCHIV
- Collective Invasion in Breast Cancer Requires a Conserved Basal Epithelial Program
- (2013) Kevin J. Cheung et al. CELL
- Progesterone receptors induce FOXO1-dependent senescence in ovarian cancer cells
- (2013) Caroline Diep et al. CELL CYCLE
- Circulating Breast Tumor Cells Exhibit Dynamic Changes in Epithelial and Mesenchymal Composition
- (2013) M. Yu et al. SCIENCE
- An EMT spectrum defines an anoikis-resistant and spheroidogenic intermediate mesenchymal state that is sensitive to e-cadherin restoration by a src-kinase inhibitor, saracatinib (AZD0530)
- (2013) R Y-J Huang et al. Cell Death & Disease
- The cancer stem cell: Cell type or cell state?
- (2012) Albert D. Donnenberg et al. CYTOMETRY PART A
- Biological Responses to TGF- in the Mammary Epithelium Show a Complex Dependency on Smad3 Gene Dosage with Important Implications for Tumor Progression
- (2012) E. A. Kohn et al. MOLECULAR CANCER RESEARCH
- Expression of Wnt3 Activates Wnt/ -Catenin Pathway and Promotes EMT-like Phenotype in Trastuzumab-Resistant HER2-Overexpressing Breast Cancer Cells
- (2012) Y. Wu et al. MOLECULAR CANCER RESEARCH
- Classifying collective cancer cell invasion
- (2012) Peter Friedl et al. NATURE CELL BIOLOGY
- Detection of circulating tumour cells with a hybrid (epithelial/mesenchymal) phenotype in patients with metastatic non-small cell lung cancer
- (2011) A Lecharpentier et al. BRITISH JOURNAL OF CANCER
- Temporal and Spatial Cooperation of Snail1 and Twist1 during Epithelial-Mesenchymal Transition Predicts for Human Breast Cancer Recurrence
- (2011) D. D. Tran et al. MOLECULAR CANCER RESEARCH
- Localization of CD44 and CD90 positive cells to the invasive front of breast tumors
- (2010) Vera S. Donnenberg et al. CYTOMETRY PART B-CLINICAL CYTOMETRY
- Collective cell migration requires suppression of actomyosin at cell–cell contacts mediated by DDR1 and the cell polarity regulators Par3 and Par6
- (2010) Cristina Hidalgo-Carcedo et al. NATURE CELL BIOLOGY
- Hypoxia, Snail and incomplete epithelial–mesenchymal transition in breast cancer
- (2009) K Lundgren et al. BRITISH JOURNAL OF CANCER
- The basics of epithelial-mesenchymal transition
- (2009) Raghu Kalluri et al. JOURNAL OF CLINICAL INVESTIGATION
- Localized and reversible TGFβ signalling switches breast cancer cells from cohesive to single cell motility
- (2009) Silvia Giampieri et al. NATURE CELL BIOLOGY
- Collective cell migration in morphogenesis, regeneration and cancer
- (2009) Peter Friedl et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started