Hypoxia and Transforming Growth Factor β Cooperate to Induce Fibulin-5 Expression in Pancreatic Cancer

Fibulin-5 Blocks Microenvironmental ROS in Pancreatic Cancer

(2015) M. Wang et al.   CANCER RESEARCH

Depletion of Carcinoma-Associated Fibroblasts and Fibrosis Induces Immunosuppression and Accelerates Pancreas Cancer with Reduced Survival

(2014) Berna C. Özdemir et al.   CANCER CELL

Stromal Elements Act to Restrain, Rather Than Support, Pancreatic Ductal Adenocarcinoma

(2014) Andrew D. Rhim et al.   CANCER CELL

Neutralizing Murine TGF R2 Promotes a Differentiated Tumor Cell Phenotype and Inhibits Pancreatic Cancer Metastasis

(2014) K. T. Ostapoff et al.   CANCER RESEARCH

Effect of Fibulin-5 on cell proliferation and invasion in human gastric cancer patients

(2014) Xiao-Yu Shi et al.   Asian Pacific Journal of Tropical Medicine

Matricellular proteins: priming the tumour microenvironment for cancer development and metastasis

(2013) G S Wong et al.   BRITISH JOURNAL OF CANCER

Collagen Signaling Enhances Tumor Progression after Anti-VEGF Therapy in a Murine Model of Pancreatic Ductal Adenocarcinoma

(2013) K. Y. Aguilera et al.   CANCER RESEARCH

Anti-VEGF antibody therapy induces tumor hypoxia and stanniocalcin 2 expression and potentiates growth of human colon cancer xenografts

(2013) Shinichiro Miyazaki et al.   INTERNATIONAL JOURNAL OF CANCER

PG545, an Angiogenesis and Heparanase Inhibitor, Reduces Primary Tumor Growth and Metastasis in Experimental Pancreatic Cancer

(2013) K. T. Ostapoff et al.   MOLECULAR CANCER THERAPEUTICS

Innate and adaptive immune cells in the tumor microenvironment

(2013) Thomas F Gajewski et al.   NATURE IMMUNOLOGY

Oncogenic Fibulin-5 Promotes Nasopharyngeal Carcinoma Cell Metastasis through the FLJ10540/AKT Pathway and Correlates with Poor Prognosis

(2013) Chung-Feng Hwang et al.   PLoS One

Isolation of Normal and Cancer-associated Fibroblasts from Fresh Tissues by Fluorescence Activated Cell Sorting (FACS)

(2013) Yoray Sharon et al.   Jove-Journal of Visualized Experiments

Stromal cells in tumor microenvironment and breast cancer

(2012) Yan Mao et al.   CANCER AND METASTASIS REVIEWS

A portrait of Transforming Growth Factor β superfamily signalling: Background matters

(2012) Daniel Horbelt et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Tumor angiogenesis: molecular pathways and therapeutic targets

(2011) Sara M Weis et al.   NATURE MEDICINE

Smac Mimetic Increases Chemotherapy Response and Improves Survival in Mice with Pancreatic Cancer

(2010) Sean P. Dineen et al.   CANCER RESEARCH

Loss of fibulin-5 binding to  1 integrins inhibits tumor growth by increasing the level of ROS

(2010) M. K. Schluterman et al.   Disease Models & Mechanisms

Fibulin-5 Is Up-regulated by Hypoxia in Endothelial Cells through a Hypoxia-inducible Factor-1 (HIF-1α)-dependent Mechanism

(2010) Anna Guadall et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

r84, a Novel Therapeutic Antibody against Mouse and Human VEGF with Potent Anti-Tumor Activity and Limited Toxicity Induction

(2010) Laura A. Sullivan et al.   PLoS One

TGF-β and immune cells: an important regulatory axis in the tumor microenvironment and progression

(2010) Li Yang et al.   TRENDS IN IMMUNOLOGY

Fibulin-2 and Fibulin-5 Cooperatively Function to Form the Internal Elastic Lamina and Protect From Vascular Injury

(2009) Shelby L. Chapman et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Fibulin-5 Suppresses Lung Cancer Invasion by Inhibiting Matrix Metalloproteinase-7 Expression

(2009) W. Yue et al.   CANCER RESEARCH

Fibulin-5, an integrin-binding matricellular protein: its function in development and disease

(2009) Hiromi Yanagisawa et al.   Journal of Cell Communication and Signaling

Fibulin-5 initiates epithelial-mesenchymal transition (EMT) and enhances EMT induced by TGF-  in mammary epithelial cells via a MMP-dependent mechanism

(2008) Y.-H. Lee et al.   CARCINOGENESIS

Basement Membrane Derived Fibulin-1 and Fibulin-5 Function as Angiogenesis Inhibitors and Suppress Tumor Growth

(2008) Liang Xie et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

LY2109761, a novel transforming growth factor   receptor type I and type II dual inhibitor, as a therapeutic approach to suppressing pancreatic cancer metastasis

(2008) D. Melisi et al.   MOLECULAR CANCER THERAPEUTICS