Regulation of heterogeneous cancer-associated fibroblasts: the molecular pathology of activated signaling pathways
出版年份 2020 全文链接
标题
Regulation of heterogeneous cancer-associated fibroblasts: the molecular pathology of activated signaling pathways
作者
关键词
-
出版物
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
Volume 39, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2020-06-16
DOI
10.1186/s13046-020-01611-0
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Applications of patient-derived tumor xenograft models and tumor organoids
- (2020) Go J. Yoshida Journal of Hematology & Oncology
- Dickkopf-3 links HSF1 and YAP/TAZ signalling to control aggressive behaviours in cancer-associated fibroblasts
- (2019) Nicola Ferrari et al. Nature Communications
- Cancer-associated fibroblasts in gastrointestinal cancer
- (2019) Hiroki Kobayashi et al. Nature Reviews Gastroenterology & Hepatology
- Heterotypic CAF-tumor spheroids promote early peritoneal metastatis of ovarian cancer
- (2019) Qinglei Gao et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Activated Fibroblast Program Orchestrates Tumor Initiation and Progression; Molecular Mechanisms and the Associated Therapeutic Strategies
- (2019) Go J. Yoshida et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Control of Invasion by Epithelial-to-Mesenchymal Transition Programs during Metastasis
- (2019) Gray W. Pearson Journal of Clinical Medicine
- Cross-Species Single-Cell Analysis of Pancreatic Ductal Adenocarcinoma Reveals Antigen-Presenting Cancer-Associated Fibroblasts
- (2019) Ela Elyada et al. Cancer Discovery
- Meflin-positive cancer-associated fibroblasts inhibit pancreatic carcinogenesis
- (2019) Yasuyuki Mizutani et al. CANCER RESEARCH
- Stromal integrin α11 regulates PDGFRβ signaling and promotes breast cancer progression
- (2019) Irina Primac et al. JOURNAL OF CLINICAL INVESTIGATION
- Inducible formation of leader cells driven by CD44 switching gives rise to collective invasion and metastases in luminal breast carcinomas
- (2019) Cuixia Yang et al. ONCOGENE
- Epigenetic changes in fibroblasts drive cancer metabolism and differentiation
- (2019) Rajeev Mishra et al. ENDOCRINE-RELATED CANCER
- Phase 1 trials of PEGylated recombinant human hyaluronidase PH20 in patients with advanced solid tumours
- (2018) Jeffrey R Infante et al. BRITISH JOURNAL OF CANCER
- Fibroblast Heterogeneity and Immunosuppressive Environment in Human Breast Cancer
- (2018) Ana Costa et al. CANCER CELL
- Matrix stiffening and EGFR cooperate to promote the collective invasion of cancer cells.
- (2018) Eloise M Grasset et al. CANCER RESEARCH
- A peek into cancer-associated fibroblasts: origins, functions and translational impact
- (2018) Valerie S. LeBleu et al. Disease Models & Mechanisms
- Involvement of partial EMT in cancer progression
- (2018) Masao Saitoh JOURNAL OF BIOCHEMISTRY
- Fibroblast heterogeneity: implications for human disease
- (2018) Magnus D. Lynch et al. JOURNAL OF CLINICAL INVESTIGATION
- miR200-regulated CXCL12β promotes fibroblast heterogeneity and immunosuppression in ovarian cancers
- (2018) Anne-Marie Givel et al. Nature Communications
- Fibroblasts Mobilize Tumor Cell Glycogen to Promote Proliferation and Metastasis
- (2018) Marion Curtis et al. Cell Metabolism
- Emerging roles of Myc in stem cell biology and novel tumor therapies
- (2018) Go J. Yoshida JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- FAP delineates heterogeneous and functionally divergent stromal cells in immune-excluded breast tumors
- (2018) Viviana Cremasco et al. Cancer Immunology Research
- An evolving story of the metastatic voyage of ovarian cancer cells: cellular and molecular orchestration of the adipose-rich metastatic microenvironment
- (2018) Takeshi Motohara et al. ONCOGENE
- Cancer-associated fibroblasts suppress SOX2-induced dysplasia in a lung squamous cancer coculture
- (2018) Shuang Chen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Periostin secreted by cancer-associated fibroblasts promotes cancer stemness in head and neck cancer by activating protein tyrosine kinase 7
- (2018) Binbin Yu et al. Cell Death & Disease
- IL-1-induced JAK/STAT signaling is antagonized by TGF-beta to shape CAF heterogeneity in pancreatic ductal adenocarcinoma
- (2018) Giulia Biffi et al. Cancer Discovery
- Mutual dependence of the MRTF–SRF and YAP–TEAD pathways in cancer-associated fibroblasts is indirect and mediated by cytoskeletal dynamics
- (2017) Charles T. Foster et al. GENES & DEVELOPMENT
- Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer
- (2017) Daniel Öhlund et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Therapeutic strategies of drug repositioning targeting autophagy to induce cancer cell death: from pathophysiology to treatment
- (2017) Go J. Yoshida Journal of Hematology & Oncology
- Activation of ROCK and MLCK tunes regional stress fiber formation and mechanics via preferential myosin light chain phosphorylation
- (2017) Elena Kassianidou et al. MOLECULAR BIOLOGY OF THE CELL
- Emerging functions of the EGFR in cancer
- (2017) Sara Sigismund et al. Molecular Oncology
- A mechanically active heterotypic E-cadherin/N-cadherin adhesion enables fibroblasts to drive cancer cell invasion
- (2017) Anna Labernadie et al. NATURE CELL BIOLOGY
- EMT, CSCs, and drug resistance: the mechanistic link and clinical implications
- (2017) Tsukasa Shibue et al. Nature Reviews Clinical Oncology
- A loop of cancer-stroma-cancer interaction promotes peritoneal metastasis of ovarian cancer via TNFα-TGFα-EGFR
- (2017) T-S Lau et al. ONCOGENE
- IL6 derived from cancer-associated fibroblasts promotes chemoresistance via CXCR7 in esophageal squamous cell carcinoma
- (2017) Y Qiao et al. ONCOGENE
- Overexpression of Yes Associated Protein 1, an Independent Prognostic Marker in Patients With Pancreatic Ductal Adenocarcinoma, Correlated With Liver Metastasis and Poor Prognosis
- (2017) Maria Teresa Salcedo Allende et al. PANCREAS
- Cancer associated fibroblasts: An essential role in the tumor microenvironment
- (2017) Leilei Tao et al. Oncology Letters
- Phenotypic and functional heterogeneity of cancer-associated fibroblast within the tumor microenvironment
- (2016) Genichiro Ishii et al. ADVANCED DRUG DELIVERY REVIEWS
- A specific, transmembrane interface regulates fibroblast activation protein (FAP) homodimerization, trafficking and exopeptidase activity
- (2016) Benjamaporn Wonganu et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- YAP/TAZ as therapeutic targets in cancer
- (2016) Francesca Zanconato et al. CURRENT OPINION IN PHARMACOLOGY
- Carcinoma-associated fibroblasts: orchestrating the composition of malignancy
- (2016) Philippe Gascard et al. GENES & DEVELOPMENT
- Emerging role of epithelial-mesenchymal transition in hepatic cancer
- (2016) Go J. Yoshida JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- IL-6 Secreted from Cancer-Associated Fibroblasts Mediates Chemoresistance in NSCLC by Increasing Epithelial-Mesenchymal Transition Signaling
- (2016) Yasushi Shintani et al. Journal of Thoracic Oncology
- The future of cancer treatment: immunomodulation, CARs and combination immunotherapy
- (2016) Danny N. Khalil et al. Nature Reviews Clinical Oncology
- Stromal Hedgehog signalling is downregulated in colon cancer and its restoration restrains tumour growth
- (2016) Marco Gerling et al. Nature Communications
- Identification of Meflin as a Potential Marker for Mesenchymal Stromal Cells
- (2016) Keiko Maeda et al. Scientific Reports
- TGFβ3-mediated induction of Periostin facilitates head and neck cancer growth and is associated with metastasis
- (2016) Xing Qin et al. Scientific Reports
- Intravital Imaging Reveals How BRAF Inhibition Generates Drug-Tolerant Microenvironments with High Integrin β1/FAK Signaling
- (2015) Eishu Hirata et al. CANCER CELL
- DDR2 facilitates hepatocellular carcinoma invasion and metastasis via activating ERK signaling and stabilizing SNAIL1
- (2015) Binhui Xie et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Metabolic reprogramming: the emerging concept and associated therapeutic strategies
- (2015) Go J. Yoshida JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Integrin α11β1 regulates cancer stromal stiffness and promotes tumorigenicity and metastasis in non-small cell lung cancer
- (2015) R Navab et al. ONCOGENE
- Understanding fibroblast heterogeneity in the skin
- (2015) Ryan R. Driskell et al. TRENDS IN CELL BIOLOGY
- Molecular mechanism underlying the tumor-promoting functions of carcinoma-associated fibroblasts
- (2015) Yali Han et al. TUMOR BIOLOGY
- Epigenetic switch drives the conversion of fibroblasts into proinvasive cancer-associated fibroblasts
- (2015) Jean Albrengues et al. Nature Communications
- Cetuximab promotes epithelial to mesenchymal transition and cancer associated fibroblasts in patients with head and neck cancer
- (2015) Sandra Schmitz et al. Oncotarget
- Cancer-Associated Fibroblasts: Their Characteristics and Their Roles in Tumor Growth
- (2015) Kazuyoshi Shiga et al. Cancers
- The IL-6/JAK/Stat3 Feed-Forward Loop Drives Tumorigenesis and Metastasis
- (2015) Qing Chang et al. NEOPLASIA
- Hedgehog Signaling Restrains Bladder Cancer Progression by Eliciting Stromal Production of Urothelial Differentiation Factors
- (2014) Kunyoo Shin et al. CANCER CELL
- Depletion of Carcinoma-Associated Fibroblasts and Fibrosis Induces Immunosuppression and Accelerates Pancreas Cancer with Reduced Survival
- (2014) Berna C. Özdemir et al. CANCER CELL
- Stromal Elements Act to Restrain, Rather Than Support, Pancreatic Ductal Adenocarcinoma
- (2014) Andrew D. Rhim et al. CANCER CELL
- The Reprogramming of Tumor Stroma by HSF1 Is a Potent Enabler of Malignancy
- (2014) Ruth Scherz-Shouval et al. CELL
- Podoplanin-Positive Cancer-Associated Fibroblasts in the Tumor Microenvironment Induce Primary Resistance to EGFR-TKIs in Lung Adenocarcinoma with EGFR Mutation
- (2014) Tatsuya Yoshida et al. CLINICAL CANCER RESEARCH
- Mechanisms of Oncostatin M-Induced Pulmonary Inflammation and Fibrosis
- (2014) A. Mozaffarian et al. JOURNAL OF IMMUNOLOGY
- Antitumor Efficacy of the Anti-Interleukin-6 (IL-6) Antibody Siltuximab in Mouse Xenograft Models of Lung Cancer
- (2014) Lanxi Song et al. Journal of Thoracic Oncology
- Histone deacetylases and their inhibitors in cancer, neurological diseases and immune disorders
- (2014) Katrina J. Falkenberg et al. NATURE REVIEWS DRUG DISCOVERY
- Three-dimensional culture of sebaceous gland cells revealing the role of prostaglandin E2-induced activation of canonical Wnt signaling
- (2013) Go J. Yoshida et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Inversed relationship between CD44 variant and c-Myc due to oxidative stress-induced canonical Wnt activation
- (2013) Go J. Yoshida et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Solid predominant histology predicts EGFR tyrosine kinase inhibitor response in patients with EGFR mutation-positive lung adenocarcinoma
- (2013) Tatsuya Yoshida et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts
- (2013) Fernando Calvo et al. NATURE CELL BIOLOGY
- Targeting CXCL12 from FAP-expressing carcinoma-associated fibroblasts synergizes with anti-PD-L1 immunotherapy in pancreatic cancer
- (2013) C. Feig et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Circulating Breast Tumor Cells Exhibit Dynamic Changes in Epithelial and Mesenchymal Composition
- (2013) M. Yu et al. SCIENCE
- The chemokine, CXCL12, is an independent predictor of poor survival in ovarian cancer
- (2012) A Popple et al. BRITISH JOURNAL OF CANCER
- Enzymatic Targeting of the Stroma Ablates Physical Barriers to Treatment of Pancreatic Ductal Adenocarcinoma
- (2012) Paolo P. Provenzano et al. CANCER CELL
- Chromatin Remodeling Underlies the Senescence-Associated Secretory Phenotype of Tumor Stromal Fibroblasts That Supports Cancer Progression
- (2012) E. Pazolli et al. CANCER RESEARCH
- Metabolic reprogramming of cancer-associated fibroblasts by TGF-β drives tumor growth: Connecting TGF-β signaling with “Warburg-like” cancer metabolism and L-lactate production
- (2012) Carmela Guido et al. CELL CYCLE
- Power Surge: Supporting Cells “Fuel” Cancer Cell Mitochondria
- (2012) Ubaldo E. Martinez-Outschoorn et al. Cell Metabolism
- HOXA9 promotes ovarian cancer growth by stimulating cancer-associated fibroblasts
- (2012) Song Yi Ko et al. JOURNAL OF CLINICAL INVESTIGATION
- High Interstitial Fluid Pressure Is Associated with Tumor-Line Specific Vascular Abnormalities in Human Melanoma Xenografts
- (2012) Trude G. Simonsen et al. PLoS One
- MicroRNAs Reprogram Normal Fibroblasts into Cancer-Associated Fibroblasts in Ovarian Cancer
- (2012) A. K. Mitra et al. Cancer Discovery
- Role of Endothelial-Mesenchymal Transition (EndoMT) in the Pathogenesis of Fibrotic Disorders
- (2011) Sonsoles Piera-Velazquez et al. AMERICAN JOURNAL OF PATHOLOGY
- ROCK and JAK1 Signaling Cooperate to Control Actomyosin Contractility in Tumor Cells and Stroma
- (2011) Victoria Sanz-Moreno et al. CANCER CELL
- Podoplanin-Positive Fibroblasts Enhance Lung Adenocarcinoma Tumor Formation: Podoplanin in Fibroblast Functions for Tumor Progression
- (2011) A. Hoshino et al. CANCER RESEARCH
- The reverse Warburg effect: Aerobic glycolysis in cancer associated fibroblasts and the tumor stroma
- (2011) Stephanos Pavlides et al. CELL CYCLE
- Interpreting mixed signals: the cell's cytokine conundrum
- (2011) Greg M Delgoffe et al. CURRENT OPINION IN IMMUNOLOGY
- Exosomes from ovarian cancer cells induce adipose tissue-derived mesenchymal stem cells to acquire the physical and functional characteristics of tumor-supporting myofibroblasts
- (2011) Jung Ah Cho et al. GYNECOLOGIC ONCOLOGY
- Role of YAP/TAZ in mechanotransduction
- (2011) Sirio Dupont et al. NATURE
- Cell-Extracellular Matrix Interactions in Normal and Diseased Skin
- (2011) F. M. Watt et al. Cold Spring Harbor Perspectives in Biology
- Cell Signaling by Receptor Tyrosine Kinases
- (2010) Mark A. Lemmon et al. CELL
- The autophagic tumor stroma model of cancer
- (2010) Stephanos Pavlides et al. CELL CYCLE
- Autophagy in cancer associated fibroblasts promotes tumor cell survival
- (2010) Ubaldo E. Martinez-Outschoorn et al. CELL CYCLE
- The Hippo Signaling Pathway in Development and Cancer
- (2010) Duojia Pan DEVELOPMENTAL CELL
- Activation of fibroblasts in cancer stroma
- (2010) Kati Räsänen et al. EXPERIMENTAL CELL RESEARCH
- Redox regulation of Wnt signalling via nucleoredoxin
- (2010) Yosuke Funato et al. FREE RADICAL RESEARCH
- Hippo signaling at a glance
- (2010) Bin Zhao et al. JOURNAL OF CELL SCIENCE
- The Rho exchange factor Arhgef1 mediates the effects of angiotensin II on vascular tone and blood pressure
- (2010) Christophe Guilluy et al. NATURE MEDICINE
- Autocrine TGF- and stromal cell-derived factor-1 (SDF-1) signaling drives the evolution of tumor-promoting mammary stromal myofibroblasts
- (2010) Y. Kojima et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Caveolin-1−/− Null Mammary Stromal Fibroblasts Share Characteristics with Human Breast Cancer-Associated Fibroblasts
- (2009) Federica Sotgia et al. AMERICAN JOURNAL OF PATHOLOGY
- Involvement of Wnt Signaling in Dermal Fibroblasts
- (2009) Kenji Kabashima et al. AMERICAN JOURNAL OF PATHOLOGY
- Transforming growth factor-β1 downregulates caveolin-1 expression and enhances sphingosine 1-phosphate signaling in cultured vascular endothelial cells
- (2009) Junsuke Igarashi et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- A chemical biology screen reveals a role for Rab21-mediated control of actomyosin contractility in fibroblast-driven cancer invasion
- (2009) S Hooper et al. BRITISH JOURNAL OF CANCER
- Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling
- (2009) Kandice R. Levental et al. CELL
- Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases
- (2009) Bryan T. MacDonald et al. DEVELOPMENTAL CELL
- Biomarkers for epithelial-mesenchymal transitions
- (2009) Michael Zeisberg et al. JOURNAL OF CLINICAL INVESTIGATION
- The basics of epithelial-mesenchymal transition
- (2009) Raghu Kalluri et al. JOURNAL OF CLINICAL INVESTIGATION
- Tumor-promoting phenotype of CD90hiprostate cancer-associated fibroblasts
- (2009) Hongjuan Zhao et al. PROSTATE
- The role of endothelial-to-mesenchymal transition in cancer progression
- (2008) S Potenta et al. BRITISH JOURNAL OF CANCER
- TGFβ in Cancer
- (2008) Joan Massagué CELL
- Podoplanin expression by cancer associated fibroblasts predicts poor prognosis of lung adenocarcinoma
- (2008) Akikazu Kawase et al. INTERNATIONAL JOURNAL OF CANCER
- Cancer as an overhealing wound: an old hypothesis revisited
- (2008) Matthias Schäfer et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Cancer-Derived Lysophosphatidic Acid Stimulates Differentiation of Human Mesenchymal Stem Cells to Myofibroblast-Like Cells
- (2007) Eun Su Jeon et al. STEM CELLS
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now