标题
Immunometabolic control of hematopoiesis
作者
关键词
Bone marrow, Hematopoietic stem cells, Metabolism, Trained immunity/myelopoiesis, Clonal hematopoiesis, Aging
出版物
MOLECULAR ASPECTS OF MEDICINE
Volume 77, Issue -, Pages 100923
出版商
Elsevier BV
发表日期
2020-11-05
DOI
10.1016/j.mam.2020.100923
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Asymmetrically Segregated Mitochondria Provide Cellular Memory of Hematopoietic Stem Cell Replicative History and Drive HSC Attrition
- (2020) Ashwini Hinge et al. Cell Stem Cell
- Interplay between Clonal Hematopoiesis of Indeterminate Potential and Metabolism
- (2020) Man K.S. Lee et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Activation of AMPK under Hypoxia: Many Roads Leading to Rome
- (2020) Franziska Dengler INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Mechanisms and rejuvenation strategies for aged hematopoietic stem cells
- (2020) Xia Li et al. Journal of Hematology & Oncology
- Regulation of the Bone Marrow Niche by Inflammation
- (2020) Ioannis Mitroulis et al. Frontiers in Immunology
- The Unique Metabolic Characteristics of Bone Marrow Adipose Tissue
- (2019) Yujue Li et al. Frontiers in Endocrinology
- Haematopoietic stem cell activity and interactions with the niche
- (2019) Sandra Pinho et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Mitochondria in the maintenance of hematopoietic stem cells new perspectives and opportunities
- (2019) Marie-Dominique Filippi et al. BLOOD
- Therapeutic targeting of trained immunity
- (2019) Willem J. M. Mulder et al. NATURE REVIEWS DRUG DISCOVERY
- Losing Sense of Self and Surroundings: Hematopoietic Stem Cell Aging and Leukemic Transformation
- (2019) Evgenia V. Verovskaya et al. TRENDS IN MOLECULAR MEDICINE
- The Roles of Cholesterol and Its Metabolites in Normal and Malignant Hematopoiesis
- (2019) Hideyuki Oguro Frontiers in Endocrinology
- Allicin alleviates lead-induced hematopoietic stem cell aging by up-regulating PKM2
- (2019) Shi-zhong Cai et al. BIOSCIENCE REPORTS
- Hematopoietic progenitor cells as integrative hubs for adaptation to and fine-tuning of inflammation
- (2019) Triantafyllos Chavakis et al. NATURE IMMUNOLOGY
- ROS-mediated PI3K activation drives mitochondrial transfer from stromal cells to hematopoietic stem cells in response to infection
- (2019) Jayna J. Mistry et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Clonal hematopoiesis in human aging and disease
- (2019) Siddhartha Jaiswal et al. SCIENCE
- Understanding intrinsic hematopoietic stem cell aging
- (2019) Eva Mejia-Ramirez et al. HAEMATOLOGICA
- Microenvironmental contributions to hematopoietic stem cell aging
- (2019) Ya-Hsuan Ho et al. HAEMATOLOGICA
- Western Diet Triggers NLRP3-Dependent Innate Immune Reprogramming
- (2018) Anette Christ et al. CELL
- Modulation of Myelopoiesis Progenitors Is an Integral Component of Trained Immunity
- (2018) Ioannis Mitroulis et al. CELL
- Hematopoietic stem cell fate through metabolic control
- (2018) Kyoko Ito et al. EXPERIMENTAL HEMATOLOGY
- Ca2+–mitochondria axis drives cell division in hematopoietic stem cells
- (2018) Terumasa Umemoto et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Tet2 promotes pathogen infection-induced myelopoiesis through mRNA oxidation
- (2018) Qicong Shen et al. NATURE
- Microbial signals drive pre-leukaemic myeloproliferation in a Tet2-deficient host
- (2018) Marlies Meisel et al. NATURE
- Diminished apoptotic priming and ATM signalling confer a survival advantage onto aged haematopoietic stem cells in response to DNA damage
- (2018) Paula Gutierrez-Martinez et al. NATURE CELL BIOLOGY
- Antagonism of PPAR-γ signaling expands human hematopoietic stem and progenitor cells by enhancing glycolysis
- (2018) Bin Guo et al. NATURE MEDICINE
- Myelodysplastic syndromes current treatment algorithm 2018
- (2018) David P. Steensma Blood Cancer Journal
- SIRT1 Activation Disrupts Maintenance of Myelodysplastic Syndrome Stem and Progenitor Cells by Restoring TET2 Function
- (2018) Jie Sun et al. Cell Stem Cell
- Glucose-regulated phosphorylation of TET2 by AMPK reveals a pathway linking diabetes to cancer
- (2018) Di Wu et al. NATURE
- Inhibition of Inflammatory Signaling in Tet2 Mutant Preleukemic Cells Mitigates Stress-Induced Abnormalities and Clonal Hematopoiesis
- (2018) Zhigang Cai et al. Cell Stem Cell
- Immunometabolic Crosstalk: An Ancestral Principle of Trained Immunity?
- (2018) Sider Penkov et al. TRENDS IN IMMUNOLOGY
- Association of Mutations Contributing to Clonal Hematopoiesis With Prognosis in Chronic Ischemic Heart Failure
- (2018) Lena Dorsheimer et al. JAMA Cardiology
- ROS signaling under metabolic stress: cross-talk between AMPK and AKT pathway
- (2017) Yang Zhao et al. Molecular Cancer
- Autophagy maintains the metabolism and function of young and old stem cells
- (2017) Theodore T. Ho et al. NATURE
- Ascorbate regulates haematopoietic stem cell function and leukaemogenesis
- (2017) Michalis Agathocleous et al. NATURE
- Regulation of mitochondrial biogenesis in erythropoiesis by mTORC1-mediated protein translation
- (2017) Xin Liu et al. NATURE CELL BIOLOGY
- The mitochondrial respiratory chain is essential for haematopoietic stem cell function
- (2017) Elena Ansó et al. NATURE CELL BIOLOGY
- DNA damage tolerance in hematopoietic stem and progenitor cells in mice
- (2017) Bas Pilzecker et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Clonal hematopoiesis associated with TET2 deficiency accelerates atherosclerosis development in mice
- (2017) José J. Fuster et al. SCIENCE
- Proliferation Drives Aging-Related Functional Decline in a Subpopulation of the Hematopoietic Stem Cell Compartment
- (2017) Kristina Kirschner et al. Cell Reports
- Effect of diabetes status and hyperglycemia on global DNA methylation and hydroxymethylation
- (2017) Jairo Arturo Pinzón-Cortés et al. Endocrine Connections
- The Dlk1-Gtl2 Locus Preserves LT-HSC Function by Inhibiting the PI3K-mTOR Pathway to Restrict Mitochondrial Metabolism
- (2016) Pengxu Qian et al. Cell Stem Cell
- FOXO3 Transcription Factor Is Essential for Protecting Hematopoietic Stem and Progenitor Cells from Oxidative DNA Damage
- (2016) Carolina L. Bigarella et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mitofusin 2 maintains haematopoietic stem cells with extensive lymphoid potential
- (2016) Larry L. Luchsinger et al. NATURE
- Specification of haematopoietic stem cell fate via modulation of mitochondrial activity
- (2016) Nicola Vannini et al. Nature Communications
- Resveratrol Supplementation in Schizophrenia Patients: A Randomized Clinical Trial Evaluating Serum Glucose and Cardiovascular Risk Factors
- (2016) Karine Zortea et al. Nutrients
- Inflamm-Aging of Hematopoiesis, Hematopoietic Stem Cells, and the Bone Marrow Microenvironment
- (2016) Larisa V. Kovtonyuk et al. Frontiers in Immunology
- TET2 Mutations Affect Non-CpG Island DNA Methylation at Enhancers and Transcription Factor-Binding Sites in Chronic Myelomonocytic Leukemia
- (2015) J. Yamazaki et al. CANCER RESEARCH
- Enhancing Hematopoietic Stem Cell Transplantation Efficacy by Mitigating Oxygen Shock
- (2015) Charlie R. Mantel et al. CELL
- Mitochondrial metabolism in hematopoietic stem cells requires functional FOXO3
- (2015) P. Rimmele et al. EMBO REPORTS
- Loss ofTET2in hematopoietic cells leads to DNA hypermethylation of active enhancers and induction of leukemogenesis
- (2015) Kasper D. Rasmussen et al. GENES & DEVELOPMENT
- Neutrophil ageing is regulated by the microbiome
- (2015) Dachuan Zhang et al. NATURE
- Exit from dormancy provokes DNA-damage-induced attrition in haematopoietic stem cells
- (2015) Dagmar Walter et al. NATURE
- A mitochondrial UPR-mediated metabolic checkpoint regulates hematopoietic stem cell aging
- (2015) M. Mohrin et al. SCIENCE
- The Sirt1 activator SRT3025 expands hematopoietic stem and progenitor cells and improves hematopoiesis in Fanconi anemia mice
- (2015) Qing-Shuo Zhang et al. Stem Cell Research
- An MTCH2 pathway repressing mitochondria metabolism regulates haematopoietic stem cell fate
- (2015) Maria Maryanovich et al. Nature Communications
- Resveratrol increases the bone marrow hematopoietic stem and progenitor cell capacity
- (2014) Pauline Rimmelé et al. AMERICAN JOURNAL OF HEMATOLOGY
- Cell-State-Specific Metabolic Dependency in Hematopoiesis and Leukemogenesis
- (2014) Ying-Hua Wang et al. CELL
- Gut Microbiota Promote Hematopoiesis to Control Bacterial Infection
- (2014) Arya Khosravi et al. Cell Host & Microbe
- A SIRT7-Dependent Acetylation Switch of GABPβ1 Controls Mitochondrial Function
- (2014) Dongryeol Ryu et al. Cell Metabolism
- AMPK at the Nexus of Energetics and Aging
- (2014) Kristopher Burkewitz et al. Cell Metabolism
- Prolonged Fasting Reduces IGF-1/PKA to Promote Hematopoietic-Stem-Cell-Based Regeneration and Reverse Immunosuppression
- (2014) Chia-Wei Cheng et al. Cell Stem Cell
- Glucose and Glutamine Metabolism Regulate Human Hematopoietic Stem Cell Lineage Specification
- (2014) Leal Oburoglu et al. Cell Stem Cell
- DNMT3A and IDH mutations in acute myeloid leukemia and other myeloid malignancies: associations with prognosis and potential treatment strategies
- (2014) A P Im et al. LEUKEMIA
- The unfolded protein response governs integrity of the haematopoietic stem-cell pool during stress
- (2014) Peter van Galen et al. NATURE
- Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells
- (2014) Johanna Flach et al. NATURE
- Metabolic requirements for the maintenance of self-renewing stem cells
- (2014) Keisuke Ito et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Clonal Hematopoiesis and Blood-Cancer Risk Inferred from Blood DNA Sequence
- (2014) Giulio Genovese et al. NEW ENGLAND JOURNAL OF MEDICINE
- Age-Related Clonal Hematopoiesis Associated with Adverse Outcomes
- (2014) Siddhartha Jaiswal et al. NEW ENGLAND JOURNAL OF MEDICINE
- Surviving change: the metabolic journey of hematopoietic stem cells
- (2014) Latika Kohli et al. TRENDS IN CELL BIOLOGY
- Rhythmic Modulation of the Hematopoietic Niche through Neutrophil Clearance
- (2013) María Casanova-Acebes et al. CELL
- Hyperglycemia Promotes Myelopoiesis and Impairs the Resolution of Atherosclerosis
- (2013) Prabhakara R. Nagareddy et al. Cell Metabolism
- Regulation of Glycolysis by Pdk Functions as a Metabolic Checkpoint for Cell Cycle Quiescence in Hematopoietic Stem Cells
- (2013) Keiyo Takubo et al. Cell Stem Cell
- Metabolic Regulation by the Mitochondrial Phosphatase PTPMT1 Is Required for Hematopoietic Stem Cell Differentiation
- (2013) Wen-Mei Yu et al. Cell Stem Cell
- Hematopoiesis
- (2013) M. Jagannathan-Bogdan et al. DEVELOPMENT
- The migration of hematopoietic progenitors from the fetal liver to the fetal bone marrow: Lessons learned and possible clinical applications
- (2013) Jesús Ciriza et al. EXPERIMENTAL HEMATOLOGY
- Deletion of Asxl1 results in myelodysplasia and severe developmental defects in vivo
- (2013) Omar Abdel-Wahab et al. JOURNAL OF EXPERIMENTAL MEDICINE
- FOXO3A directs a protective autophagy program in haematopoietic stem cells
- (2013) Matthew R. Warr et al. NATURE
- ASXL1 Mutations Promote Myeloid Transformation through Loss of PRC2-Mediated Gene Repression
- (2012) Omar Abdel-Wahab et al. CANCER CELL
- Metabolic Plasticity in Stem Cell Homeostasis and Differentiation
- (2012) Clifford D.L. Folmes et al. Cell Stem Cell
- Recurrent somatic TET2 mutations in normal elderly individuals with clonal hematopoiesis
- (2012) Lambert Busque et al. NATURE GENETICS
- A PML–PPAR-δ pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance
- (2012) Keisuke Ito et al. NATURE MEDICINE
- Oncometabolite 2-Hydroxyglutarate Is a Competitive Inhibitor of α-Ketoglutarate-Dependent Dioxygenases
- (2011) Wei Xu et al. CANCER CELL
- Tet2 Loss Leads to Increased Hematopoietic Stem Cell Self-Renewal and Myeloid Transformation
- (2011) Kelly Moran-Crusio et al. CANCER CELL
- Accumulating Mitochondrial DNA Mutations Drive Premature Hematopoietic Aging Phenotypes Distinct from Physiological Stem Cell Aging
- (2011) Gudmundur L. Norddahl et al. Cell Stem Cell
- AMP-activated protein kinase--an energy sensor that regulates all aspects of cell function
- (2011) D. G. Hardie GENES & DEVELOPMENT
- ApoE regulates hematopoietic stem cell proliferation, monocytosis, and monocyte accumulation in atherosclerotic lesions in mice
- (2011) Andrew J. Murphy et al. JOURNAL OF CLINICAL INVESTIGATION
- The autophagy protein Atg7 is essential for hematopoietic stem cell maintenance
- (2011) Monika Mortensen et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Clonal analysis reveals multiple functional defects of aged murine hematopoietic stem cells
- (2011) Brad Dykstra et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The dual mTORC1 and mTORC2 inhibitor AZD8055 has anti-tumor activity in acute myeloid leukemia
- (2011) L Willems et al. LEUKEMIA
- Dnmt3a is essential for hematopoietic stem cell differentiation
- (2011) Grant A Challen et al. NATURE GENETICS
- AKT1 and AKT2 maintain hematopoietic stem cell function by regulating reactive oxygen species
- (2010) M. M. Juntilla et al. BLOOD
- Hematopoietic Stem Cell Quiescence Promotes Error-Prone DNA Repair and Mutagenesis
- (2010) Mary Mohrin et al. Cell Stem Cell
- The Distinct Metabolic Profile of Hematopoietic Stem Cells Reflects Their Location in a Hypoxic Niche
- (2010) Tugba Simsek et al. Cell Stem Cell
- Regulation of the HIF-1α Level Is Essential for Hematopoietic Stem Cells
- (2010) Keiyo Takubo et al. Cell Stem Cell
- Hypoxia-Inducible Factors and the Response to Hypoxic Stress
- (2010) Amar J. Majmundar et al. MOLECULAR CELL
- Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cells
- (2010) Daisuke Nakada et al. NATURE
- Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells
- (2010) Boyi Gan et al. NATURE
- The emerging mechanisms of isoform-specific PI3K signalling
- (2010) Bart Vanhaesebroeck et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- ATP-Binding Cassette Transporters and HDL Suppress Hematopoietic Stem Cell Proliferation
- (2010) L. Yvan-Charvet et al. SCIENCE
- Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies
- (2009) O. Abdel-Wahab et al. BLOOD
- Constitutively active AKT depletes hematopoietic stem cells and induces leukemia in mice
- (2009) M. G. Kharas et al. BLOOD
- Loss of heterozygosity 4q24 and TET2 mutations associated with myelodysplastic/myeloproliferative neoplasms
- (2009) A. M. Jankowska et al. BLOOD
- Systems biology of stem cell fate and cellular reprogramming
- (2009) Ben D. MacArthur et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1
- (2009) M. Tahiliani et al. SCIENCE
- mTOR Regulation and Therapeutic Rejuvenation of Aging Hematopoietic Stem Cells
- (2009) C. Chen et al. Science Signaling
- Oxygen homeostasis
- (2009) Gregg L. Semenza Wiley Interdisciplinary Reviews-Systems Biology and Medicine
- Mechanisms of Asymmetric Stem Cell Division
- (2008) Juergen A. Knoblich CELL
- DNA-damage repair; the good, the bad, and the ugly
- (2008) Razqallah Hakem EMBO JOURNAL
- TSC–mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species
- (2008) Chong Chen et al. JOURNAL OF EXPERIMENTAL MEDICINE
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