AKT1 and AKT2 maintain hematopoietic stem cell function by regulating reactive oxygen species

Constitutively active AKT depletes hematopoietic stem cells and induces leukemia in mice

(2009) M. G. Kharas et al.   BLOOD

Regulation of Reactive Oxygen Species and Genomic Stability in Hematopoietic Stem Cells

(2008) Kazuhito Naka et al.   ANTIOXIDANTS & REDOX SIGNALING

CD150- cells are transiently reconstituting multipotent progenitors with little or no stem cell activity

(2008) M. J. Kiel et al.   BLOOD

Akt Determines Replicative Senescence and Oxidative or Oncogenic Premature Senescence and Sensitizes Cells to Oxidative Apoptosis

(2008) Veronique Nogueira et al.   CANCER CELL

Hematopoietic Stem Cell Responsiveness to Exogenous Signals Is Limited by Caspase-3

(2008) Viktor Janzen et al.   Cell Stem Cell

TSC–mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species

(2008) Chong Chen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Bone marrow long label-retaining cells reside in the sinusoidal hypoxic niche

(2007) Yoshiaki Kubota et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS