The unfolded protein response governs integrity of the haematopoietic stem-cell pool during stress

Reduced Lymphoid Lineage Priming Promotes Human Hematopoietic Stem Cell Expansion

(2014) Peter van Galen et al.   Cell Stem Cell

Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia

(2014) Liran I. Shlush et al.   NATURE

HIF-2α Protects Human Hematopoietic Stem/Progenitors and Acute Myeloid Leukemic Cells from Apoptosis Induced by Endoplasmic Reticulum Stress

(2013) Kevin Rouault-Pierre et al.   Cell Stem Cell

ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death

(2013) Jaeseok Han et al.   NATURE CELL BIOLOGY

The transcriptional architecture of early human hematopoiesis identifies multilevel control of lymphoid commitment

(2013) Elisa Laurenti et al.   NATURE IMMUNOLOGY

ER Stress Causes Rapid Loss of Intestinal Epithelial Stemness through Activation of the Unfolded Protein Response

(2013) Jarom Heijmans et al.   Cell Reports

ERdj4 Protein Is a Soluble Endoplasmic Reticulum (ER) DnaJ Family Protein That Interacts with ER-associated Degradation Machinery

(2012) Chunwei Walter Lai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Discovery of 7-Methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (GSK2606414), a Potent and Selective First-in-Class Inhibitor of Protein Kinase R (PKR)-like Endoplasmic Reticulum Kinase (PERK)

(2012) Jeffrey M. Axten et al.   JOURNAL OF MEDICINAL CHEMISTRY

Acute Inducible Ablation of GRP78 Reveals Its Role in Hematopoietic Stem Cell Survival, Lymphogenesis and Regulation of Stress Signaling

(2012) Shiuan Wey et al.   PLoS One

Accumulation of oxidative DNA damage restricts the self-renewal capacity of human hematopoietic stem cells

(2011) T. Yahata et al.   BLOOD

Phosphorylation of eIF2 Facilitates Ribosomal Bypass of an Inhibitory Upstream ORF to EnhanceCHOPTranslation

(2011) Lakshmi Reddy Palam et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress

(2011) Ira Tabas et al.   NATURE CELL BIOLOGY

Isolation of Single Human Hematopoietic Stem Cells Capable of Long-Term Multilineage Engraftment

(2011) F. Notta et al.   SCIENCE

The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation

(2011) P. Walter et al.   SCIENCE

Cytoscape Web: an interactive web-based network browser

(2010) Christian T. Lopes et al.   BIOINFORMATICS

A Distinctive DNA Damage Response in Human Hematopoietic Stem Cells Reveals an Apoptosis-Independent Role for p53 in Self-Renewal

(2010) Michael Milyavsky et al.   Cell Stem Cell

Revised map of the human progenitor hierarchy shows the origin of macrophages and dendritic cells in early lymphoid development

(2010) Sergei Doulatov et al.   NATURE IMMUNOLOGY

ELDA: Extreme limiting dilution analysis for comparing depleted and enriched populations in stem cell and other assays

(2009) Yifang Hu et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Stems Cells and the Pathways to Aging and Cancer

(2008) Derrick J. Rossi et al.   CELL

Conversion of Red Fluorescent Protein into a Bright Blue Probe

(2008) Oksana M. Subach et al.   CHEMISTRY & BIOLOGY

Stable knockdown of microRNA in vivo by lentiviral vectors

(2008) Bernhard Gentner et al.   NATURE METHODS