标题
Therapeutic targeting of trained immunity
作者
关键词
-
出版物
NATURE REVIEWS DRUG DISCOVERY
Volume -, Issue -, Pages -
出版商
Springer Nature
发表日期
2019-04-10
DOI
10.1038/s41573-019-0025-4
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- TNF inhibitors in rheumatoid arthritis and spondyloarthritis: Are they the same?
- (2018) Andrea Rubbert-Roth et al. AUTOIMMUNITY REVIEWS
- Western Diet Triggers NLRP3-Dependent Innate Immune Reprogramming
- (2018) Anette Christ et al. CELL
- Modulation of Myelopoiesis Progenitors Is an Integral Component of Trained Immunity
- (2018) Ioannis Mitroulis et al. CELL
- BCG Educates Hematopoietic Stem Cells to Generate Protective Innate Immunity against Tuberculosis
- (2018) Eva Kaufmann et al. CELL
- Metabolic Induction of Trained Immunity through the Mevalonate Pathway
- (2018) Siroon Bekkering et al. CELL
- High-dimensional single-cell analysis predicts response to anti-PD-1 immunotherapy
- (2018) Carsten Krieg et al. NATURE MEDICINE
- Efficacy and safety assessment of a TRAF6-targeted nanoimmunotherapy in atherosclerotic mice and non-human primates
- (2018) Marnix Lameijer et al. Nature Biomedical Engineering
- Innate immune memory in the brain shapes neurological disease hallmarks
- (2018) Ann-Christin Wendeln et al. NATURE
- Nanoimmunotherapy to treat ischaemic heart disease
- (2018) Raphaël Duivenvoorden et al. Nature Reviews Cardiology
- Inhibiting Inflammation with Myeloid Cell-Specific Nanobiologics Promotes Organ Transplant Acceptance
- (2018) Mounia S. Braza et al. IMMUNITY
- The infarcted myocardium solicits GM-CSF for the detrimental oversupply of inflammatory leukocytes
- (2017) Atsushi Anzai et al. JOURNAL OF EXPERIMENTAL MEDICINE
- De-novo and acquired resistance to immune checkpoint targeting
- (2017) Nicholas L Syn et al. LANCET ONCOLOGY
- Tumor necrosis factor-alpha inhibitors suppress CCL2 chemokine in monocytes via epigenetic modification
- (2017) Yi-Ching Lin et al. MOLECULAR IMMUNOLOGY
- Targeting a CAR to the TRAC locus with CRISPR/Cas9 enhances tumour rejection
- (2017) Justin Eyquem et al. NATURE
- Anti-colony-stimulating factor therapies for inflammatory and autoimmune diseases
- (2017) John A. Hamilton et al. NATURE REVIEWS DRUG DISCOVERY
- Immunogenicity and loss of response to TNF inhibitors: implications for rheumatoid arthritis treatment
- (2017) Joachim R. Kalden et al. Nature Reviews Rheumatology
- Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease
- (2017) Paul M Ridker et al. NEW ENGLAND JOURNAL OF MEDICINE
- Uric acid priming in human monocytes is driven by the AKT–PRAS40 autophagy pathway
- (2017) Tania O. Crişan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Friend or Foe? The Ambiguous Role of Innate Lymphoid Cells in Cancer Development
- (2017) Jochen Mattner et al. TRENDS IN IMMUNOLOGY
- Therapeutic miRNA and siRNA: Moving from Bench to Clinic as Next Generation Medicine
- (2017) Chiranjib Chakraborty et al. Molecular Therapy-Nucleic Acids
- Immune Checkpoint Therapies in Prostate Cancer
- (2016) Sangeeta Goswami et al. CANCER JOURNAL
- Glutaminolysis and Fumarate Accumulation Integrate Immunometabolic and Epigenetic Programs in Trained Immunity
- (2016) Rob J.W. Arts et al. Cell Metabolism
- A Phase II Efficacy and Safety, Open-Label, Multicenter Study of Imprime PGG Injection in Combination With Cetuximab in Patients With Stage IV KRAS-Mutant Colorectal Cancer
- (2016) Neil H. Segal et al. Clinical Colorectal Cancer
- Allergen-Experienced Group 2 Innate Lymphoid Cells Acquire Memory-like Properties and Enhance Allergic Lung Inflammation
- (2016) Itziar Martinez-Gonzalez et al. IMMUNITY
- Immune checkpoint inhibition in ovarian cancer
- (2016) Junzo Hamanishi et al. INTERNATIONAL IMMUNOLOGY
- Cellular Innate Immunity: An Old Game with New Players
- (2016) Georg Gasteiger et al. Journal of Innate Immunity
- Cellular metabolism of myeloid cells in sepsis
- (2016) Rob J. W. Arts et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy
- (2016) Lena M. Kranz et al. NATURE
- Iron oxide nanoparticles inhibit tumour growth by inducing pro-inflammatory macrophage polarization in tumour tissues
- (2016) Saeid Zanganeh et al. Nature Nanotechnology
- Safety profiles of anti-CTLA-4 and anti-PD-1 antibodies alone and in combination
- (2016) Celine Boutros et al. Nature Reviews Clinical Oncology
- Epigenetic drug discovery: breaking through the immune barrier
- (2016) David F. Tough et al. NATURE REVIEWS DRUG DISCOVERY
- Development of immuno-oncology drugs — from CTLA4 to PD1 to the next generations
- (2016) Axel Hoos NATURE REVIEWS DRUG DISCOVERY
- Immune cell screening of a nanoparticle library improves atherosclerosis therapy
- (2016) Jun Tang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Trained immunity: A program of innate immune memory in health and disease
- (2016) M. G. Netea et al. SCIENCE
- Immunometabolic circuits in trained immunity
- (2016) Rob J.W. Arts et al. SEMINARS IN IMMUNOLOGY
- In Vivo PET Imaging of HDL in Multiple Atherosclerosis Models
- (2016) Carlos Pérez-Medina et al. JACC-Cardiovascular Imaging
- Augmenting drug–carrier compatibility improves tumour nanotherapy efficacy
- (2016) Yiming Zhao et al. Nature Communications
- Immunometabolic Pathways in BCG-Induced Trained Immunity
- (2016) Rob J.W. Arts et al. Cell Reports
- Transcriptional and metabolic reprogramming induce an inflammatory phenotype in non-medullary thyroid carcinoma-induced macrophages
- (2016) Rob J. W. Arts et al. OncoImmunology
- Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential
- (2015) Padmanee Sharma et al. CELL
- Inhibition of Dectin-1 Signaling Ameliorates Colitis by Inducing Lactobacillus-Mediated Regulatory T Cell Expansion in the Intestine
- (2015) Ce Tang et al. Cell Host & Microbe
- The Epigenetic Memory of Monocytes and Macrophages as a Novel Drug Target in Atherosclerosis
- (2015) Siroon Bekkering et al. CLINICAL THERAPEUTICS
- Atherosclerotic Vascular Disease in the Autoimmune Rheumatologic Patient
- (2015) Rekha Mankad Current Atherosclerosis Reports
- PET Imaging of Tumor-Associated Macrophages with 89Zr-Labeled High-Density Lipoprotein Nanoparticles
- (2015) C. Perez-Medina et al. JOURNAL OF NUCLEAR MEDICINE
- Innate immune memory: a paradigm shift in understanding host defense
- (2015) Mihai G Netea et al. NATURE IMMUNOLOGY
- The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome–mediated inflammatory disease
- (2015) Yun-Hee Youm et al. NATURE MEDICINE
- A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases
- (2015) Rebecca C Coll et al. NATURE MEDICINE
- Targeting GM-CSF in inflammatory diseases
- (2015) Ian P. Wicks et al. Nature Reviews Rheumatology
- Innate lymphoid cells: A new paradigm in immunology
- (2015) G. Eberl et al. SCIENCE
- The future of immune checkpoint therapy
- (2015) P. Sharma et al. SCIENCE
- Trained immunity in newborn infants of HBV-infected mothers
- (2015) Michelle Hong et al. Nature Communications
- NLRP3 inflammasome and its inhibitors: a review
- (2015) Bo-Zong Shao et al. Frontiers in Pharmacology
- Inhibiting macrophage proliferation suppresses atherosclerotic plaque inflammation
- (2015) J. Tang et al. Science Advances
- Oxidized Low-Density Lipoprotein Induces Long-Term Proinflammatory Cytokine Production and Foam Cell Formation via Epigenetic Reprogramming of Monocytes
- (2014) Siroon Bekkering et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- BCG-induced trained immunity in NK cells: Role for non-specific protection to infection
- (2014) Johanneke Kleinnijenhuis et al. CLINICAL IMMUNOLOGY
- Group 2 Innate Lymphoid Cells Are Critical for the Initiation of Adaptive T Helper 2 Cell-Mediated Allergic Lung Inflammation
- (2014) Timotheus Y.F. Halim et al. IMMUNITY
- Anti-programmed-death-receptor-1 treatment with pembrolizumab in ipilimumab-refractory advanced melanoma: a randomised dose-comparison cohort of a phase 1 trial
- (2014) Caroline Robert et al. LANCET
- Clinical use of dendritic cells for cancer therapy
- (2014) Sébastien Anguille et al. LANCET ONCOLOGY
- Intracellular α-ketoglutarate maintains the pluripotency of embryonic stem cells
- (2014) Bryce W. Carey et al. NATURE
- Neutrophils prime a long-lived effector macrophage phenotype that mediates accelerated helminth expulsion
- (2014) Fei Chen et al. NATURE IMMUNOLOGY
- Interferon-Tau Attenuates Uptake of Nanoparticles and Secretion of Interleukin-1β in Macrophages
- (2014) Kyoko Hara et al. PLoS One
- Polymeric synthetic nanoparticles for the induction of antigen-specific immunological tolerance
- (2014) Roberto A. Maldonado et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The microbial metabolite butyrate regulates intestinal macrophage function via histone deacetylase inhibition
- (2014) Pamela V. Chang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- mTOR- and HIF-1 -mediated aerobic glycolysis as metabolic basis for trained immunity
- (2014) S.-C. Cheng et al. SCIENCE
- Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity
- (2014) S. Saeed et al. SCIENCE
- A statin-loaded reconstituted high-density lipoprotein nanoparticle inhibits atherosclerotic plaque inflammation
- (2014) Raphaël Duivenvoorden et al. Nature Communications
- Autophagy Controls BCG-Induced Trained Immunity and the Response to Intravesical BCG Therapy for Bladder Cancer
- (2014) Kathrin Buffen et al. PLoS Pathogens
- Long-Lasting Effects of BCG Vaccination on Both Heterologous Th1/Th17 Responses and Innate Trained Immunity
- (2013) Johanneke Kleinnijenhuis et al. Journal of Innate Immunity
- Multifunctional Gold Nanoparticles for Diagnosis and Therapy of Disease
- (2013) Aneta J. Mieszawska et al. MOLECULAR PHARMACEUTICS
- CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation
- (2013) Frederick J Sheedy et al. NATURE IMMUNOLOGY
- Identification of Benzimidazole Diamides as Selective Inhibitors of the Nucleotide-Binding Oligomerization Domain 2 (NOD2) Signaling Pathway
- (2013) David J. Rickard et al. PLoS One
- Reversal of Immunoparalysis in HumansIn Vivo
- (2012) Jenneke Leentjens et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Candida albicans Infection Affords Protection against Reinfection via Functional Reprogramming of Monocytes
- (2012) Jessica Quintin et al. Cell Host & Microbe
- Targeted polymeric therapeutic nanoparticles: design, development and clinical translation
- (2012) Nazila Kamaly et al. CHEMICAL SOCIETY REVIEWS
- Peptidoglycan and muramyl dipeptide from Staphylococcus aureus induce the expression of VEGF-A in human limbal fibroblasts with the participation of TLR2-NFκB and NOD2-EGFR
- (2012) Marco Adán Juárez–Verdayes et al. GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
- Fate Mapping Reveals Origins and Dynamics of Monocytes and Tissue Macrophages under Homeostasis
- (2012) Simon Yona et al. IMMUNITY
- Proinflammatory cytokine signaling required for the generation of natural killer cell memory
- (2012) Joseph C. Sun et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases
- (2012) Charles A. Dinarello et al. NATURE REVIEWS DRUG DISCOVERY
- Bacille Calmette-Guerin induces NOD2-dependent nonspecific protection from reinfection via epigenetic reprogramming of monocytes
- (2012) J. Kleinnijenhuis et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Epigenetic regulation of immune cell functions during post-septic immunosuppression
- (2011) William F. Carson et al. Epigenetics
- Innate and adaptive immune responses to cell death
- (2011) Kenneth L. Rock et al. IMMUNOLOGICAL REVIEWS
- Drug targeting to tumors: Principles, pitfalls and (pre-) clinical progress
- (2011) Twan Lammers et al. JOURNAL OF CONTROLLED RELEASE
- Cancer immunotherapy comes of age
- (2011) Ira Mellman et al. NATURE
- Therapeutic siRNA silencing in inflammatory monocytes in mice
- (2011) Florian Leuschner et al. NATURE BIOTECHNOLOGY
- Perspectives and opportunities for nanomedicine in the management of atherosclerosis
- (2011) Mark E. Lobatto et al. NATURE REVIEWS DRUG DISCOVERY
- Cancer immunotherapy – revisited
- (2011) W. Joost Lesterhuis et al. NATURE REVIEWS DRUG DISCOVERY
- Mammalian target of rapamycin signaling is crucial for joint destruction in experimental arthritis and is activated in osteoclasts from patients with rheumatoid arthritis
- (2010) Daniel Cejka et al. ARTHRITIS AND RHEUMATISM
- Toll-like receptor-induced changes in glycolytic metabolism regulate dendritic cell activation
- (2010) C. M. Krawczyk et al. BLOOD
- RGD peptide functionalized and reconstituted high-density lipoprotein nanoparticles as a versatile and multimodal tumor targeting molecular imaging probe
- (2010) Wei Chen et al. FASEB JOURNAL
- NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
- (2010) Peter Duewell et al. NATURE
- Imaging and quantifying the morphology of an organic–inorganic nanoparticle at the sub-nanometre level
- (2010) Matti M. van Schooneveld et al. Nature Nanotechnology
- Nanotechnological strategies for engineering complex tissues
- (2010) Tal Dvir et al. Nature Nanotechnology
- Nanoparticulate Assemblies of Amphiphiles and Diagnostically Active Materials for Multimodality Imaging
- (2009) Willem J. M. Mulder et al. ACCOUNTS OF CHEMICAL RESEARCH
- Laminarin-mediated targeting to Dectin-1 enhances antigen-specific immune responses
- (2009) Jianhui Xie et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Dissecting the role of mTOR: Lessons from mTOR inhibitors
- (2009) Ryan J.O. Dowling et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- Epigenetic regulation of the alternatively activated macrophage phenotype
- (2009) M. Ishii et al. BLOOD
- Hyperglycemia Induces a Dynamic Cooperativity of Histone Methylase and Demethylase Enzymes Associated With Gene-Activating Epigenetic Marks That Coexist on the Lysine Tail
- (2009) D. Brasacchio et al. DIABETES
- Adaptive immune features of natural killer cells
- (2009) Joseph C. Sun et al. NATURE
- Knocking down barriers: advances in siRNA delivery
- (2009) Kathryn A. Whitehead et al. NATURE REVIEWS DRUG DISCOVERY
- Identification of Splenic Reservoir Monocytes and Their Deployment to Inflammatory Sites
- (2009) F. K. Swirski et al. SCIENCE
- Reactivation of rheumatoid arthritis after pregnancy: Increased phagocyte and recurring lymphocyte gene activity
- (2008) Thomas Häupl et al. ARTHRITIS AND RHEUMATISM
- Cancer-related inflammation
- (2008) Alberto Mantovani et al. NATURE
- Host–pathogen interactions in sepsis
- (2007) Tom van der Poll et al. LANCET INFECTIOUS DISEASES
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now