标题
Targeting Sirtuin 1 signaling pathway by ginsenosides
作者
关键词
SIRT1, NAD, Ginseng, Ginsenosides, Energy metabolism
出版物
JOURNAL OF ETHNOPHARMACOLOGY
Volume 268, Issue -, Pages 113657
出版商
Elsevier BV
发表日期
2020-12-01
DOI
10.1016/j.jep.2020.113657
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Ginsenoside Rp1, A Ginsenoside Derivative, Augments Anti-Cancer Effects of Actinomycin D via Downregulation of an AKT-SIRT1 Pathway
- (2020) Un-Jung Yun et al. Cancers
- Ginsenoside 20(S)-protopanaxadiol attenuates depressive-like behaviour and neuroinflammation in chronic unpredictable mild stress-induced depressive rats
- (2020) Ning Jiang et al. BEHAVIOURAL BRAIN RESEARCH
- Ginsenoside Rg2 Ameliorates High-Fat Diet-Induced Metabolic Disease through SIRT1
- (2020) Bo Cheng et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Ginsenoside Rb1 reduces H2O2‑induced HUVEC dysfunction by stimulating the sirtuin‑1/AMP‑activated protein kinase pathway
- (2020) Zhenda Zheng et al. Molecular Medicine Reports
- Ginsenoside Rg1 protects against Sca‑1+ HSC/HPC cell aging by regulating the SIRT1‑FOXO3 and SIRT3‑SOD2 signaling pathways in a γ‑ray irradiation‑induced aging mice model
- (2020) Yan‑Long Tang et al. Experimental and Therapeutic Medicine
- Ginsenoside Rk1 alleviates LPS-induced depression-like behavior in mice by promoting BDNF and suppressing the neuroinflammatory response
- (2020) Zhiman Li et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- IgA Nephropathy Benefits from Compound K Treatment by Inhibiting NF-κB/NLRP3 Inflammasome and Enhancing Autophagy and SIRT1
- (2020) Chung-Yao Wu et al. JOURNAL OF IMMUNOLOGY
- Ginsenoside Rg1 ameliorates chronic social defeat stress-induced depressive-like behaviors and hippocampal neuroinflammation
- (2020) Ning Jiang et al. LIFE SCIENCES
- Ginsenoside Rd Ameliorates Auditory Cortex Injury Associated With Military Aviation Noise-Induced Hearing Loss by Activating SIRT1/PGC-1α Signaling Pathway
- (2020) Xue-min Chen et al. Frontiers in Physiology
- Ginsenoside Rb2 alleviates myocardial ischemia/reperfusion injury in rats through SIRT1 activation
- (2020) Yan Xue et al. JOURNAL OF FOOD SCIENCE
- Sirtuins in Metabolic and Epigenetic Regulation of Stem Cells
- (2019) Yi Fang et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Resveratrol ameliorates gouty inflammation via upregulation of sirtuin 1 to promote autophagy in gout patients
- (2019) Qi-Bin Yang et al. INFLAMMOPHARMACOLOGY
- SIRT1 promotes GLUT1 expression and bladder cancer progression via regulation of glucose uptake
- (2019) Jia Chen et al. Human Cell
- Neuroprotective Effects of Ginsenosides against Cerebral Ischemia
- (2019) Zhekang Cheng et al. MOLECULES
- Sweroside Alleviated LPS-Induced Inflammation via SIRT1 Mediating NF-κB and FOXO1 Signaling Pathways in RAW264.7 Cells
- (2019) Rui Wang et al. MOLECULES
- Study on Antidepressant Activity of Pseudo-Ginsenoside HQ on Depression-Like Behavior in Mice
- (2019) Li-xue Chen et al. MOLECULES
- Distinct Roles of the NAD+-Sirt1 and FAD-LSD1 Pathways in Metabolic Response and Tissue Development
- (2019) Mitsuyoshi Nakao et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- 20(S)-Protopanaxadiol Inhibits Angiotensin II-Induced Epithelial- Mesenchymal Transition by Downregulating SIRT1
- (2019) Yuchen Wang et al. Frontiers in Pharmacology
- Nicotinamide phosphoribosyltransferase postpones rat bone marrow mesenchymal stem cell senescence by mediating NAD+–Sirt1 signaling
- (2019) Chenchen Pi et al. Aging-US
- Cytoplasmic SIRT1 inhibits cell migration and invasion by impeding epithelial–mesenchymal transition in ovarian carcinoma
- (2019) Tong Yang et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Feeding restriction alleviates high carbohydrate diet-induced oxidative stress and inflammation of Megalobrama amblycephala by activating the AMPK-SIRT1 pathway
- (2019) Chao Xu et al. FISH & SHELLFISH IMMUNOLOGY
- Partially Hydrolyzed Guar Gum Attenuates d-Galactose-Induced Oxidative Stress and Restores Gut Microbiota in Rats
- (2019) Xiaoyan Liu et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Stereoisomer-specific ginsenoside 20(S)-Rg3 reverses replicative senescence of human diploid fibroblasts via Akt-mTOR-Sirtuin signaling
- (2019) Kyeong-Eun Yang et al. Journal of Ginseng Research
- Protective Effects of Lanosterol Synthase Up-Regulation in UV-B-Induced Oxidative Stress
- (2019) Hui Hua et al. Frontiers in Pharmacology
- CD38 Deficiency Alleviates D-Galactose-Induced Myocardial Cell Senescence Through NAD+/Sirt1 Signaling Pathway
- (2019) Ling-Fang Wang et al. Frontiers in Physiology
- Seminal SIRT1‐oxidative stress relationship in infertile oligoasthenoteratozoospermic men with varicocele after its surgical repair
- (2019) Taymour Mostafa et al. ANDROLOGIA
- Repurposing of Nitroxoline Drug for the Prevention of Neurodegeneration
- (2019) Truong Van Hau et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Inducible Cardiac-Specific Deletion of Sirt1 in Male Mice Reveals Progressive Cardiac Dysfunction and Sensitization of the Heart to Pressure Overload
- (2019) Maria-Nieves Sanz et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Ginsenoside Rb1 Attenuates High Glucose-Induced Oxidative Injury via the NAD-PARP-SIRT Axis in Rat Retinal Capillary Endothelial Cells
- (2019) Chunlan Fan et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Ginsenoside Rb1 alleviates ox-LDL-induced vascular endothelium senescence via the SIRT1/Beclin-1/autophagy axis
- (2019) Guangyao Shi et al. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
- Calorie Restriction in Adulthood Reduces Hepatic Disorders Induced by Transient Postnatal Overfeeding in Mice
- (2019) Catherine Yzydorczyk et al. Nutrients
- MicroRNA-22 inhibition prevents doxorubicin-induced cardiotoxicity via upregulating SIRT1
- (2019) Can Xu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- 1,4-Dihydropyridine (DHP) suppresses against oxidative stress in nucleus pulposus via activating sirtuin-1
- (2019) Yuxin Song et al. BIOMEDICINE & PHARMACOTHERAPY
- Metformin alleviates oxidative stress and enhances autophagy in diabetic kidney disease via AMPK/SIRT1-FoxO1 pathway
- (2019) Huiwen Ren et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Hydrogen sulfide attenuates cigarette smoke-induced airway remodeling by upregulating SIRT1 signaling pathway
- (2019) Ruijuan Guan et al. Redox Biology
- Loss of sirtuin 1 and mitofusin 2 contributes to enhanced ischemia/reperfusion injury in aged livers
- (2018) Sung Kook Chun et al. AGING CELL
- Aging impairs beige adipocyte differentiation of mesenchymal stem cells via the reduced expression of Sirtuin 1
- (2018) Vuong Cat Khanh et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- SIRT1 promotes proliferation, migration, and invasion of breast cancer cell line MCF-7 by upregulating DNA polymerase delta1 (POLD1)
- (2018) Yifang Xu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- SIRT1 regulates inflammation response of macrophages in sepsis mediated by long noncoding RNA
- (2018) Yanhui Jia et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- SIRT1 activator isolated from artificial gastric juice incubate of total saponins in stems and leaves of Panax ginseng
- (2018) Xiu-Wei Yang et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Acetylshikonin from Zicao attenuates cognitive impairment and hippocampus senescence in d -galactose-induced aging mouse model via upregulating the expression of SIRT1
- (2018) Qisen Li et al. BRAIN RESEARCH BULLETIN
- HGF and BFGF Secretion by Human Adipose-Derived Stem Cells Improves Ovarian Function During Natural Aging via Activation of the SIRT1/FOXO1 Signaling Pathway
- (2018) Chenyue Ding et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Melatonin attenuates airway inflammation via SIRT1 dependent inhibition of NLRP3 inflammasome and IL-1β in rats with COPD
- (2018) Zhenyu Peng et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Sirt1 alleviates LPS induced inflammation of periodontal ligament fibroblasts via downregulation of TLR4
- (2018) Kexin Li et al. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
- Ginsenoside 25-OCH3-PPD Promotes Activity of LXRs To Ameliorate P2X7R-Mediated NLRP3 Inflammasome in the Development of Hepatic Fibrosis
- (2018) Xin Han et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- miR-221 negatively regulates inflammation and insulin sensitivity in white adipose tissue by repression of sirtuin-1 (SIRT1)
- (2018) Jie Peng et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- OUP accepted manuscript
- (2018) JOURNAL OF NUTRITION
- Role and Possible Mechanisms of Sirt1 in Depression
- (2018) Guofang Lu et al. Oxidative Medicine and Cellular Longevity
- LC-MS based metabolic and metabonomic studies of Panax ginseng
- (2018) Wei Wu et al. PHYTOCHEMICAL ANALYSIS
- Functional role of ginseng-derived compounds in cancer
- (2018) Akash Ahuja et al. Journal of Ginseng Research
- Sirtuins and NAD + in the Development and Treatment of Metabolic and Cardiovascular Diseases
- (2018) Alice E. Kane et al. CIRCULATION RESEARCH
- Chikusetsusaponin V Inhibits LPS-Activated Inflammatory Responses via SIRT1/NF-κB Signaling Pathway in RAW264.7 Cells
- (2018) Qin Yuan et al. INFLAMMATION
- Effects of Ginsenoside Rg3 on fatigue resistance and SIRT1 in aged rats
- (2018) Qi-Yu Yang et al. TOXICOLOGY
- PARP1 inhibitor (PJ34) improves the function of aging-induced endothelial progenitor cells by preserving intracellular NAD+ levels and increasing SIRT1 activity
- (2018) Siyuan Zha et al. Stem Cell Research & Therapy
- SIRT1 deacetylase in aging-induced neuromuscular degeneration and amyotrophic lateral sclerosis
- (2018) Adrianna Z. Herskovits et al. AGING CELL
- Prostaglandin E2 down-regulates sirtuin 1 (SIRT1), leading to elevated levels of aromatase, providing insights into the obesity–breast cancer connection
- (2018) Kotha Subbaramaiah et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The roles of sirtuins family in cell metabolism during tumor development
- (2018) Shunqin Zhu et al. SEMINARS IN CANCER BIOLOGY
- Suppressive effects of rare ginsenosides, Rk1 and Rg5, on HMGB1-mediated septic responses
- (2018) Ji-Eun Kim et al. FOOD AND CHEMICAL TOXICOLOGY
- Intestinal Epithelial Sirtuin 1 Regulates Intestinal Inflammation During Aging in Mice by Altering the Intestinal Microbiota
- (2017) Alicia S. Wellman et al. GASTROENTEROLOGY
- Sirtuin 1 protects the aging heart from contractile dysfunction mediated through the inhibition of endoplasmic reticulum stress-mediated apoptosis in cardiac-specific Sirtuin 1 knockout mouse model
- (2017) Yu-Juei Hsu et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- Ginsenoside Rb2 Alleviates Hepatic Lipid Accumulation by Restoring Autophagy via Induction of Sirt1 and Activation of AMPK
- (2017) Qi Huang et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Blocking SIRT1 inhibits cell proliferation and promotes aging through the PI3K/AKT pathway
- (2017) Hongyan Li et al. LIFE SCIENCES
- Sirtuin 1 attenuates inflammation and hepatocellular damage in liver transplant ischemia/Reperfusion: From mouse to human
- (2017) Kojiro Nakamura et al. LIVER TRANSPLANTATION
- Magnolol attenuates the inflammation and apoptosis through the activation of SIRT1 in experimental stroke rats
- (2017) Dong-Quan Kou et al. Pharmacological Reports
- Tucum-do-Cerrado (Bactris setosa Mart.) May Promote Anti-Aging Effect by Upregulating SIRT1-Nrf2 Pathway and Attenuating Oxidative Stress and Inflammation
- (2017) Marcela da Cunha et al. Nutrients
- Role of ginsenosides in reactive oxygen species-mediated anticancer therapy
- (2017) Islam Sodrul et al. Oncotarget
- Role of ginsenosides, the main active components of Panax ginseng , in inflammatory responses and diseases
- (2017) Ji Hye Kim et al. Journal of Ginseng Research
- Ginseng: An Nonnegligible Natural Remedy for Healthy Aging
- (2017) Yong Yang et al. Aging and Disease
- Mitochondrial composition and function under the control of hypoxia
- (2017) Dominik C. Fuhrmann et al. Redox Biology
- Common SIRT1 variants modify the effect of abdominal adipose tissue on aging-related lung function decline
- (2016) Ivan Curjuric et al. AGE
- SIRT1 promotes epithelial–mesenchymal transition and metastasis in colorectal cancer by regulating Fra-1 expression
- (2016) Feifei Cheng et al. CANCER LETTERS
- Mir-217 promotes inflammation and fibrosis in high glucose cultured rat glomerular mesangial cells via Sirt1/HIF-1α signaling pathway
- (2016) Ying Shao et al. DIABETES-METABOLISM RESEARCH AND REVIEWS
- Characterization of oxygenated metabolites of ginsenoside Rg 1 in plasma and urine of rat
- (2016) Jing-Rong Wang et al. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
- SIRT1 Mediates Depression-Like Behaviors in the Nucleus Accumbens
- (2016) H.-D. Kim et al. JOURNAL OF NEUROSCIENCE
- Metabolism of 20(S)-Ginsenoside Rg2 by Rat Liver Microsomes: Bioactivation to SIRT1-Activating Metabolites
- (2016) Li-Yuan Ma et al. MOLECULES
- Screening SIRT1 Activators from Medicinal Plants as Bioactive Compounds against Oxidative Damage in Mitochondrial Function
- (2016) Yi Wang et al. Oxidative Medicine and Cellular Longevity
- Expression of Leptin and Sirtuin-1 is associated with poor prognosis in patients with osteosarcoma
- (2016) Helin Feng et al. PATHOLOGY RESEARCH AND PRACTICE
- Cysteine cathepsins control hepatic NF-κB-dependent inflammation via sirtuin-1 regulation
- (2016) Álvaro de Mingo et al. Cell Death & Disease
- Resveratrol serves as a protein-substrate interaction stabilizer in human SIRT1 activation
- (2016) Xuben Hou et al. Scientific Reports
- Negative reciprocal regulation between Sirt1 and Per2 modulates the circadian clock and aging
- (2016) Rui-Hong Wang et al. Scientific Reports
- New SIRT1 activator from alkaline hydrolysate of total saponins in the stems-leaves of Panax ginseng
- (2015) Li-Yuan Ma et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Structural basis for allosteric, substrate-dependent stimulation of SIRT1 activity by resveratrol
- (2015) Duanfang Cao et al. GENES & DEVELOPMENT
- Distinctive role of SIRT1 expression on tumor invasion and metastasis in breast cancer by molecular subtype
- (2015) Yul Ri Chung et al. HUMAN PATHOLOGY
- Characterization of Oxygenated Metabolites of Ginsenoside Rb1 in Plasma and Urine of Rat
- (2015) Jing-Rong Wang et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Anti-inflammatory Mechanism of Ginseng Saponin Metabolite Rh3 in Lipopolysaccharide-Stimulated Microglia: Critical Role of 5′-Adenosine Monophosphate-Activated Protein Kinase Signaling Pathway
- (2015) Yu Young Lee et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Recent advances in ginseng as cancer therapeutics: a functional and mechanistic overview
- (2015) Alice S. T. Wong et al. NATURAL PRODUCT REPORTS
- Overexpression of Sirtuin-1 is associated with poor clinical outcome in esophageal squamous cell carcinoma
- (2015) Zhenyue He et al. TUMOR BIOLOGY
- Korean Red Ginseng attenuates ethanol-induced steatosis and oxidative stress via AMPK/Sirt1 activation
- (2015) Jae Yun Han et al. Journal of Ginseng Research
- SIRT1 and stem cells: In the forefront with cardiovascular disease, neurodegeneration and cancer
- (2015) Kenneth Maiese World Journal of Stem Cells
- Overexpression of SIRT1 promotes metastasis through epithelial-mesenchymal transition in hepatocellular carcinoma
- (2015) Chong Hao et al. BMC CANCER
- Deacetylation-mediated interaction of SIRT1-HMGB1 improves survival in a mouse model of endotoxemia
- (2015) Jung Seok Hwang et al. Scientific Reports
- Mitochondrial aldehyde dehydrogenase 2 accentuates aging-induced cardiac remodeling and contractile dysfunction: role of AMPK, Sirt1, and mitochondrial function
- (2014) Yingmei Zhang et al. FREE RADICAL BIOLOGY AND MEDICINE
- Ginsenoside Rb1 Prevents H2O2-Induced HUVEC Senescence by Stimulating Sirtuin-1 Pathway
- (2014) Zhiming Song et al. PLoS One
- SIRT1 and other sirtuins in metabolism
- (2014) Hung-Chun Chang et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Ginsenoside Rc modulates Akt/FoxO1 pathways and suppresses oxidative stress
- (2013) Dae Hyun Kim et al. ARCHIVES OF PHARMACAL RESEARCH
- Structural and Functional Analysis of Human SIRT1
- (2013) Andrew M. Davenport et al. JOURNAL OF MOLECULAR BIOLOGY
- Evidence for a Common Mechanism of SIRT1 Regulation by Allosteric Activators
- (2013) B. P. Hubbard et al. SCIENCE
- SIRT1 and energy metabolism
- (2012) X. Li ACTA BIOCHIMICA ET BIOPHYSICA SINICA
- Sirtuins as regulators of metabolism and healthspan
- (2012) Riekelt H. Houtkooper et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Mitochondrial Metabolism, Sirtuins, and Aging
- (2012) M. N. Sack et al. Cold Spring Harbor Perspectives in Biology
- Protective effects and mechanisms of sirtuins in the nervous system
- (2011) Feng Zhang et al. PROGRESS IN NEUROBIOLOGY
- PARP-1 inhibition does not restore oxidant-mediated reduction in SIRT1 activity
- (2010) Samuel Caito et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- FoxO1 Mediates an Autofeedback Loop Regulating SIRT1 Expression
- (2010) Shiqin Xiong et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Uncoupling of Endothelial Nitric Oxide Synthase after Experimental Subarachnoid Hemorrhage
- (2010) Mohammed Sabri et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Acetylation of Tau Inhibits Its Degradation and Contributes to Tauopathy
- (2010) Sang-Won Min et al. NEURON
- Ginseng Compounds: An Update on their Molecular Mechanisms and Medical Applications
- (2009) Jian-Ming Lu et al. Current Vascular Pharmacology
- SIRT1 Modulation of the Acetylation Status, Cytosolic Localization, and Activity of LKB1
- (2008) Fan Lan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Sirt1 protects against high-fat diet-induced metabolic damage
- (2008) P. T. Pfluger et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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