miR-221 negatively regulates inflammation and insulin sensitivity in white adipose tissue by repression of sirtuin-1 (SIRT1)

MiR-377 promotes white adipose tissue inflammation and decreases insulin sensitivity in obesity via suppression of sirtuin-1 (SIRT1)

(2017) Jie Peng et al.   Oncotarget

miR-221 activates the NF-κB pathway by targeting A20

(2016) Dongjiu Zhao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The mir-221/222 Cluster is a Key Player in Vascular Biology via the Fine-Tuning of Endothelial Cell Physiology

(2016) Tanja Celic et al.   Current Vascular Pharmacology

Obesity-associated Inflammation Induces microRNA-155 Expression in Adipocytes and Adipose Tissue: Outcome on Adipocyte Function

(2016) Esma Karkeni et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Obesity Statistics

(2016) Kristy Breuhl Smith et al.   PRIMARY CARE

SIRT1 suppresses adipogenesis by activating Wnt/β-catenin signaling in vivo and in vitro

(2016) Yuanfei Zhou et al.   Oncotarget

SIRT1 inhibits adipogenesis and promotes myogenic differentiation in C3H10T1/2 pluripotent cells by regulating Wnt signaling

(2015) Yuanfei Zhou et al.   Cell and Bioscience

Inflammation triggers specific microRNA profiles in human adipocytes and macrophages and in their supernatants

(2015) Francisco José Ortega et al.   Clinical Epigenetics

Adipocyte SIRT1 knockout promotes PPARγ activity, adipogenesis and insulin sensitivity in chronic-HFD and obesity

(2015) Rafael Mayoral et al.   Molecular Metabolism

MicroRNA expression altered by diet: Can food be medicinal?

(2014) Joshua D. Palmer et al.   AGEING RESEARCH REVIEWS

Identification of anti-adipogenic proteins in adult bovine serum suppressing 3T3-L1 preadipocyte differentiation

(2014) Jeongho Park et al.   BMB Reports

Role of histone acetyltransferases and histone deacetylases in adipocyte differentiation and adipogenesis

(2014) Yuanfei Zhou et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

A microRNA 221– and 222–Mediated Feedback Loop Maintains Constitutive Activation of NFκB and STAT3 in Colorectal Cancer Cells

(2014) Sanhong Liu et al.   GASTROENTEROLOGY

IL-6 and TNF-α Induced Obesity-Related Inflammatory Response Through Transcriptional Regulation of miR-146b

(2014) Chunmei Shi et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

miR-221/222 Promotes S-Phase Entry and Cellular Migration in Control of Basal-Like Breast Cancer

(2014) Yuan Li et al.   MOLECULES

MicroRNAs Regulate Human Adipocyte Lipolysis: Effects of miR-145 Are Linked to TNF-α

(2014) Silvia Lorente-Cebrián et al.   PLoS One

Human adipose microRNA-221 is upregulated in obesity and affects fat metabolism downstream of leptin and TNF-α

(2013) A. Meerson et al.   DIABETOLOGIA

MicroRNA-146b promotes adipogenesis by suppressing the SIRT1-FOXO1 cascade

(2013) Jiyun Ahn et al.   EMBO Molecular Medicine

MiR-221 promotes the development of androgen independence in prostate cancer cells via downregulation of HECTD2 and RAB1A

(2013) T Sun et al.   ONCOGENE

SIRT1 in Type 2 Diabetes: Mechanisms and Therapeutic Potential

(2013) Munehiro Kitada et al.   Diabetes & Metabolism Journal

High-Fat Diet Triggers Inflammation-Induced Cleavage of SIRT1 in Adipose Tissue To Promote Metabolic Dysfunction

(2012) Angeliki Chalkiadaki et al.   Cell Metabolism

SirT1 Regulates Adipose Tissue Inflammation

(2011) M. P. Gillum et al.   DIABETES

NF-kB and c-Jun induce the expression of the oncogenic miR-221 and miR-222 in prostate carcinoma and glioblastoma cells

(2011) S. Galardi et al.   NUCLEIC ACIDS RESEARCH

Macrophages, Inflammation, and Insulin Resistance

(2010) Jerrold M. Olefsky et al.   Annual Review of Physiology

MiRNA Expression Profile of Human Subcutaneous Adipose and during Adipocyte Differentiation

(2010) Francisco J. Ortega et al.   PLoS One

Impact of Reference Gene Selection for Target Gene Normalization on Experimental Outcome Using Real-Time qRT-PCR in Adipocytes

(2010) Bradley S. Ferguson et al.   PLoS One

MicroRNA 132 Regulates Nutritional Stress-Induced Chemokine Production through Repression of SirT1

(2009) Jay C. Strum et al.   MOLECULAR ENDOCRINOLOGY

CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity

(2009) Satoshi Nishimura et al.   NATURE MEDICINE

High Efficiency Lipid-Based siRNA Transfection of Adipocytes in Suspension

(2009) Gail Kilroy et al.   PLoS One

SIRT1 Exerts Anti-Inflammatory Effects and Improves Insulin Sensitivity in Adipocytes

(2008) T. Yoshizaki et al.   MOLECULAR AND CELLULAR BIOLOGY