标题
Key chemokines direct migration of immune cells in solid tumors
作者
关键词
-
出版物
CANCER GENE THERAPY
Volume -, Issue -, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2021-02-20
DOI
10.1038/s41417-021-00303-x
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- CCL2-CCR2 axis recruits tumor associated macrophages to induce immune evasion through PD-1 signaling in esophageal carcinogenesis
- (2020) Hui Yang et al. Molecular Cancer
- BL-8040, a CXCR4 antagonist, in combination with pembrolizumab and chemotherapy for pancreatic cancer: the COMBAT trial
- (2020) Bruno Bockorny et al. NATURE MEDICINE
- Regulatory T cells in cancer immunosuppression — implications for anticancer therapy
- (2019) Yosuke Togashi et al. Nature Reviews Clinical Oncology
- CXCR4, but not CXCR3, drives CD8+ T-cell entry into and migration through the murine bone marrow
- (2019) Marieke Goedhart et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Mobilization of CD8+ T Cells via CXCR4 Blockade Facilitates PD-1 Checkpoint Therapy in Human Pancreatic Cancer
- (2019) Yongwoo David Seo et al. CLINICAL CANCER RESEARCH
- Intratumoral Activity of the CXCR3 Chemokine System Is Required for the Efficacy of Anti-PD-1 Therapy
- (2019) Melvyn T. Chow et al. IMMUNITY
- Chemokines and other mediators in the development and functional organization of lymph nodes
- (2019) Nadine Eckert et al. IMMUNOLOGICAL REVIEWS
- CCL5 promotes breast cancer recurrence through macrophage recruitment in residual tumors
- (2019) Andrea Walens et al. eLife
- Cooperation between Constitutive and Inducible Chemokines Enables T Cell Engraftment and Immune Attack in Solid Tumors
- (2019) Denarda Dangaj et al. CANCER CELL
- Recent Advances targeting CCR5 for Cancer and its Role in Immuno-Oncology
- (2019) Xuanmao Jiao et al. CANCER RESEARCH
- Phase 1b study of a small molecule antagonist of human chemokine (C-C motif) receptor 2 (PF-04136309) in combination with nab-paclitaxel/gemcitabine in first-line treatment of metastatic pancreatic ductal adenocarcinoma
- (2019) Marcus Noel et al. INVESTIGATIONAL NEW DRUGS
- Systemic Interferon-γ Increases MHC Class I Expression and T-cell Infiltration in Cold Tumors: Results of a Phase 0 Clinical Trial
- (2019) Shihong Zhang et al. Cancer Immunology Research
- CCR4 Blockade Depletes Regulatory T Cells and Prolongs Survival in a Canine Model of Bladder Cancer
- (2019) Shingo Maeda et al. Cancer Immunology Research
- Enhanced Bone Marrow Homing of Natural Killer Cells Following mRNA Transfection With Gain-of-Function Variant CXCR4R334X
- (2019) Emily Levy et al. Frontiers in Immunology
- Context Drives Diversification of Monocytes and Neutrophils in Orchestrating the Tumor Microenvironment
- (2019) Juhee Jeong et al. Frontiers in Immunology
- Tumor Associated Neutrophils. Their Role in Tumorigenesis, Metastasis, Prognosis and Therapy
- (2019) Maria Teresa Masucci et al. Frontiers in Oncology
- Tumor‐associated macrophages secrete CC‐chemokine ligand 2 and induce tamoxifen resistance by activating PI3K/Akt/mTOR in breast cancer
- (2019) Dongbo Li et al. CANCER SCIENCE
- Chemokines and their receptors promoting the recruitment of myeloid-derived suppressor cells into the tumor
- (2019) Bao-Hua Li et al. MOLECULAR IMMUNOLOGY
- MCP-1 is overexpressed in triple-negative breast cancers and drives cancer invasiveness and metastasis
- (2018) Pranabananda Dutta et al. BREAST CANCER RESEARCH AND TREATMENT
- NK Cells Stimulate Recruitment of cDC1 into the Tumor Microenvironment Promoting Cancer Immune Control
- (2018) Jan P. Böttcher et al. CELL
- Overall survival in a trial of orally administered CCR2 inhibitor CCX872 in locally advanced/metastatic pancreatic cancer: Correlation with blood monocyte counts.
- (2018) David Linehan et al. JOURNAL OF CLINICAL ONCOLOGY
- CXCR4 antagonist (BL-8040) to enhance antitumor effects by increasing tumor infiltration of antigen-specific effector T-cells.
- (2018) Pankaj Gaur et al. JOURNAL OF CLINICAL ONCOLOGY
- CCR5/CCL5 axis interaction promotes migratory and invasiveness of pancreatic cancer cells
- (2018) Santosh Kumar Singh et al. Scientific Reports
- The Expanding Therapeutic Perspective of CCR5 Blockade
- (2018) Luca Vangelista et al. Frontiers in Immunology
- Interferon-Gamma at the Crossroads of Tumor Immune Surveillance or Evasion
- (2018) Flávia Castro et al. Frontiers in Immunology
- Tumor-associated macrophages secrete CCL2 and induce the invasive phenotype of human breast epithelial cells through upregulation of ERO1-α and MMP-9
- (2018) Seungeun Lee et al. CANCER LETTERS
- CXCR3-deficient natural killer cells fail to migrate to B16F10 melanoma cells
- (2018) Juyoung Kim et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Cxcr1 mediates recruitment of neutrophils and supports proliferation of tumor-initiating astrocytes in vivo
- (2018) Davalyn Powell et al. Scientific Reports
- The Role of CXC Chemokine Receptors 1–4 on Immune Cells in the Tumor Microenvironment
- (2018) Katharina Helene Susek et al. Frontiers in Immunology
- Cyclooxygenase-2 in cancer: A review
- (2018) Nasser Hashemi Goradel et al. JOURNAL OF CELLULAR PHYSIOLOGY
- CD8+ cytotoxic T lymphocytes in cancer immunotherapy: A review
- (2018) Bagher Farhood et al. JOURNAL OF CELLULAR PHYSIOLOGY
- High expression of CCL2 in tumor cells and abundant infiltration with CD14 positive macrophages predict early relapse in breast cancer
- (2018) Marja Heiskala et al. VIRCHOWS ARCHIV
- Vascular Targeting to Increase the Efficiency of Immune Checkpoint Blockade in Cancer
- (2018) Maria Georganaki et al. Frontiers in Immunology
- Mature dendritic cells correlate with favorable immune infiltrate and improved prognosis in ovarian carcinoma patients
- (2018) Iva Truxova et al. Journal for ImmunoTherapy of Cancer
- The TRAIL-Induced Cancer Secretome Promotes a Tumor-Supportive Immune Microenvironment via CCR2
- (2017) Torsten Hartwig et al. MOLECULAR CELL
- Regulatory T Cells: Central Concepts from Ontogeny to Therapy
- (2017) Bernard Khor TRANSFUSION MEDICINE REVIEWS
- Discovery of AZD-2098 and AZD-1678, Two Potent and Bioavailable CCR4 Receptor Antagonists
- (2017) Nicholas Kindon et al. ACS Medicinal Chemistry Letters
- CCR5 Directs the Mobilization of CD11b + Gr1 + Ly6C low Polymorphonuclear Myeloid Cells from the Bone Marrow to the Blood to Support Tumor Development
- (2017) Elias Hawila et al. Cell Reports
- Myeloid-Derived Suppressor Cells
- (2017) Dmitry I. Gabrilovich Cancer Immunology Research
- CCL3 augments tumor rejection and enhances CD8+ T cell infiltration through NK and CD103+ dendritic cell recruitment via IFNγ
- (2017) Frederick Allen et al. OncoImmunology
- Chemokines and Chemokine Receptors in Lymphoid Tissue Dynamics
- (2016) Olga Schulz et al. Annual Review of Immunology
- CXCL9 and CXCL10 predict survival and are regulated by cyclooxygenase inhibition in advanced serous ovarian cancer
- (2016) Holger Bronger et al. BRITISH JOURNAL OF CANCER
- Tumoral Immune Cell Exploitation in Colorectal Cancer Metastases Can Be Targeted Effectively by Anti-CCR5 Therapy in Cancer Patients
- (2016) Niels Halama et al. CANCER CELL
- Intratumoral interferon-gamma increases chemokine production but fails to increase T cell infiltration of human melanoma metastases
- (2016) Ileana S. Mauldin et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- CCL2 Produced by the Glioma Microenvironment Is Essential for the Recruitment of Regulatory T Cells and Myeloid-Derived Suppressor Cells
- (2016) Alan L. Chang et al. CANCER RESEARCH
- Chemoattractant Receptors BLT1 and CXCR3 Regulate Antitumor Immunity by Facilitating CD8+T Cell Migration into Tumors
- (2016) Zinal S. Chheda et al. JOURNAL OF IMMUNOLOGY
- Targeting tumour-associated macrophages with CCR2 inhibition in combination with FOLFIRINOX in patients with borderline resectable and locally advanced pancreatic cancer: a single-centre, open-label, dose-finding, non-randomised, phase 1b trial
- (2016) Timothy M Nywening et al. LANCET ONCOLOGY
- Targeting natural killer cells in cancer immunotherapy
- (2016) Camille Guillerey et al. NATURE IMMUNOLOGY
- Toll-like receptor-5 agonist, entolimod, suppresses metastasis and induces immunity by stimulating an NK-dendritic-CD8+T-cell axis
- (2016) Craig M. Brackett et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Neutrophils in the Tumor Microenvironment
- (2016) Davalyn R. Powell et al. TRENDS IN IMMUNOLOGY
- Immune infiltrates in the breast cancer microenvironment: detection, characterization and clinical implication
- (2016) Samantha Burugu et al. Breast Cancer
- Targeting the CCL2-CCR2 signaling axis in cancer metastasis
- (2016) Su Yin Lim et al. Oncotarget
- CXCR2-Dependent Accumulation of Tumor-Associated Neutrophils Regulates T-cell Immunity in Pancreatic Ductal Adenocarcinoma
- (2016) T. Chao et al. Cancer Immunology Research
- CCL2 as a potential therapeutic target for clear cell renal cell carcinoma
- (2016) Ryuichiro Arakaki et al. Cancer Medicine
- CCL2/CCR2 Regulates the Tumor Microenvironment in HER-2/neu-Driven Mammary Carcinomas in Mice
- (2016) Xuguang Chen et al. PLoS One
- Mogamulizumab: 2 birds, 1 stone
- (2015) R. A. Wilcox BLOOD
- Metastasis Suppressors Regulate the Tumor Microenvironment by Blocking Recruitment of Prometastatic Tumor-Associated Macrophages
- (2015) C. Frankenberger et al. CANCER RESEARCH
- Phase Ia Study of FoxP3+ CD4 Treg Depletion by Infusion of a Humanized Anti-CCR4 Antibody, KW-0761, in Cancer Patients
- (2015) K. Kurose et al. CLINICAL CANCER RESEARCH
- Engineering NK Cells Modified With an EGFRvIII-specific Chimeric Antigen Receptor to Overexpress CXCR4 Improves Immunotherapy of CXCL12/SDF-1α-secreting Glioblastoma
- (2015) Nadja Müller et al. JOURNAL OF IMMUNOTHERAPY
- Melanoma-intrinsic β-catenin signalling prevents anti-tumour immunity
- (2015) Stefani Spranger et al. NATURE
- Prognostic and predictive significance of immune cells infiltrating cutaneous melanoma
- (2015) Andrea Ladányi Pigment Cell & Melanoma Research
- Obesity Triggers Enhanced MDSC Accumulation in Murine Renal Tumors via Elevated Local Production of CCL2
- (2015) Malika Hale et al. PLoS One
- The Chemokine System in Innate Immunity
- (2015) Caroline L. Sokol et al. Cold Spring Harbor Perspectives in Biology
- Non-redundant requirement for CXCR3 signalling during tumoricidal T-cell trafficking across tumour vascular checkpoints
- (2015) M. E. Mikucki et al. Nature Communications
- Targeting CXCR1 on breast cancer stem cells: signaling pathways and clinical application modelling
- (2015) Laura Brandolini et al. Oncotarget
- CXCL11-Armed oncolytic poxvirus elicits potent antitumor immunity and shows enhanced therapeutic efficacy
- (2015) Zuqiang Liu et al. OncoImmunology
- Hydrogel dual delivered celecoxib and anti-PD-1 synergistically improve antitumor immunity
- (2015) Yongkui Li et al. OncoImmunology
- The Chemokine CCL2 Increases Prostate Tumor Growth and Bone Metastasis through Macrophage and Osteoclast Recruitment
- (2015) Kosuke Mizutani et al. NEOPLASIA
- Chemokines and Chemokine Receptors: Positioning Cells for Host Defense and Immunity
- (2014) Jason W. Griffith et al. Annual Review of Immunology
- CXCL10-induced migration of adoptively transferred human natural killer cells toward solid tumors causes regression of tumor growth in vivo
- (2014) Erik Wennerberg et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Reduction of Regulatory T Cells by Mogamulizumab, a Defucosylated Anti-CC Chemokine Receptor 4 Antibody, in Patients with Aggressive/Refractory Mycosis Fungoides and Sezary Syndrome
- (2014) X. Ni et al. CLINICAL CANCER RESEARCH
- Toll-like Receptor Agonist Imiquimod Facilitates Antigen-Specific CD8+ T-cell Accumulation in the Genital Tract Leading to Tumor Control through IFN
- (2014) R.-S. Soong et al. CLINICAL CANCER RESEARCH
- Tumor-Associated Macrophages: From Mechanisms to Therapy
- (2014) Roy Noy et al. IMMUNITY
- Immune cells: plastic players along colorectal cancer progression
- (2014) Giuseppe Di Caro et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Multicenter Phase II Study of Mogamulizumab (KW-0761), a Defucosylated Anti-CC Chemokine Receptor 4 Antibody, in Patients With Relapsed Peripheral T-Cell Lymphoma and Cutaneous T-Cell Lymphoma
- (2014) Michinori Ogura et al. JOURNAL OF CLINICAL ONCOLOGY
- Cutting Edge: CXCR4 Is Critical for CD8+ Memory T Cell Homeostatic Self-Renewal but Not Rechallenge Self-Renewal
- (2014) J. Chaix et al. JOURNAL OF IMMUNOLOGY
- Chemokines in Cancer
- (2014) M. T. Chow et al. Cancer Immunology Research
- A novel recombinant protein of IP10-EGFRvIIIscFv and CD8+ cytotoxic T lymphocytes synergistically inhibits the growth of implanted glioma in mice
- (2013) Xuan Wang et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Dendritic Cells in Tumor-Associated Tertiary Lymphoid Structures Signal a Th1 Cytotoxic Immune Contexture and License the Positive Prognostic Value of Infiltrating CD8+ T Cells
- (2013) J. Goc et al. CANCER RESEARCH
- Oncology Meets Immunology: The Cancer-Immunity Cycle
- (2013) Daniel S. Chen et al. IMMUNITY
- CXCR2-mediated tumor-associated neutrophil recruitment is regulated by IFN-β
- (2013) J. Jablonska et al. INTERNATIONAL JOURNAL OF CANCER
- Targeting CXCL12 from FAP-expressing carcinoma-associated fibroblasts synergizes with anti-PD-L1 immunotherapy in pancreatic cancer
- (2013) C. Feig et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Anti-CCR4 mAb selectively depletes effector-type FoxP3+CD4+ regulatory T cells, evoking antitumor immune responses in humans
- (2013) D. Sugiyama et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Safety, tolerability, pharmacokinetics and pharmacodynamics of GSK2239633, a CC-chemokine receptor 4 antagonist, in healthy male subjects: results from an open-label and from a randomised study
- (2013) Anthony Cahn et al. BMC Pharmacology & Toxicology
- PD-1 Blockade Enhances T-cell Migration to Tumors by Elevating IFN- Inducible Chemokines
- (2012) W. Peng et al. CANCER RESEARCH
- Targeting Tumor-Infiltrating Macrophages Decreases Tumor-Initiating Cells, Relieves Immunosuppression, and Improves Chemotherapeutic Responses
- (2012) J. B. Mitchem et al. CANCER RESEARCH
- Tumor-associated neutrophils: friend or foe?
- (2012) Z. G. Fridlender et al. CARCINOGENESIS
- CCR2-Dependent Recruitment of Macrophages by Tumor-Educated Mesenchymal Stromal Cells Promotes Tumor Development and Is Mimicked by TNFα
- (2012) Guangwen Ren et al. Cell Stem Cell
- A review on CXCR4/CXCL12 axis in oncology: No place to hide
- (2012) Urszula M. Domanska et al. EUROPEAN JOURNAL OF CANCER
- Overexpression of CXCL5 mediates neutrophil infiltration and indicates poor prognosis for hepatocellular carcinoma
- (2012) Shao-Lai Zhou et al. HEPATOLOGY
- The CXCR2 Antagonist, SCH-527123, Shows Antitumor Activity and Sensitizes Cells to Oxaliplatin in Preclinical Colon Cancer Models
- (2012) Yan Ning et al. MOLECULAR CANCER THERAPEUTICS
- Neutrophil chemokines secreted by tumor cells mount a lung antimetastatic response during renal cell carcinoma progression
- (2012) M A López-Lago et al. ONCOGENE
- A CCR4 antagonist combined with vaccines induces antigen-specific CD8+ T cells and tumor immunity against self antigens
- (2011) H. Pere et al. BLOOD
- An immune-active tumor microenvironment favors clinical response to ipilimumab
- (2011) Rui-Ru Ji et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Early Detection of Tumor Cells by Innate Immune Cells Leads to Treg Recruitment through CCL22 Production by Tumor Cells
- (2011) J. Faget et al. CANCER RESEARCH
- Monocytic CCR2+ Myeloid-Derived Suppressor Cells Promote Immune Escape by Limiting Activated CD8 T-cell Infiltration into the Tumor Microenvironment
- (2011) A. M. Lesokhin et al. CANCER RESEARCH
- Role of CXCR3 Ligands in IL-7/IL-7R -Fc-Mediated Antitumor Activity in Lung Cancer
- (2011) A. Andersson et al. CLINICAL CANCER RESEARCH
- CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis
- (2011) Bin-Zhi Qian et al. NATURE
- CXCL12-CXCR4 chemokine signaling is essential for NK-cell development in adult mice
- (2010) M. Noda et al. BLOOD
- Small molecule antagonists for CXCR2 and CXCR1 inhibit human colon cancer liver metastases
- (2010) Michelle L. Varney et al. CANCER LETTERS
- CXCR1 blockade selectively targets human breast cancer stem cells in vitro and in xenografts
- (2010) Christophe Ginestier et al. JOURNAL OF CLINICAL INVESTIGATION
- Targeting the CXCR4-CXCL12 Axis Mobilizes Autologous Hematopoietic Stem Cells and Prolongs Islet Allograft Survival via Programmed Death Ligand 1
- (2010) P. Fiorina et al. JOURNAL OF IMMUNOLOGY
- Chemokine Expression in Melanoma Metastases Associated with CD8+ T-Cell Recruitment
- (2009) H. Harlin et al. CANCER RESEARCH
- Regulatory T Cells Recruited through CCL22/CCR4 Are Selectively Activated in Lymphoid Infiltrates Surrounding Primary Breast Tumors and Lead to an Adverse Clinical Outcome
- (2009) M. Gobert et al. CANCER RESEARCH
- Small-Molecule Antagonists for CXCR2 and CXCR1 Inhibit Human Melanoma Growth by Decreasing Tumor Cell Proliferation, Survival, and Angiogenesis
- (2009) S. Singh et al. CLINICAL CANCER RESEARCH
- Biomolecular Network Reconstruction Identifies T-Cell Homing Factors Associated With Survival in Colorectal Cancer
- (2009) Bernhard Mlecnik et al. GASTROENTEROLOGY
- The inflammatory chemokines CCL2 and CCL5 in breast cancer
- (2008) Gali Soria et al. CANCER LETTERS
- Natural Killer Cell Accumulation in Tumors Is Dependent on IFN- and CXCR3 Ligands
- (2008) M. Wendel et al. CANCER RESEARCH
- CCL17 and CCL22 chemokines within tumor microenvironment are related to accumulation of Foxp3+ regulatory T cells in gastric cancer
- (2008) Yoshiki Mizukami et al. INTERNATIONAL JOURNAL OF CANCER
- Chemokines and Their Receptors: Drug Targets in Immunity and Inflammation
- (2007) Antonella Viola et al. Annual Review of Pharmacology and Toxicology
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started