Intratumoral interferon-gamma increases chemokine production but fails to increase T cell infiltration of human melanoma metastases

A randomized pilot trial testing the safety and immunologic effects of a MAGE-A3 protein plus AS15 immunostimulant administered into muscle or into dermal/subcutaneous sites

(2015) Craig L. Slingluff et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Intratumoral immunotherapy for melanoma

(2015) Manisha Singh et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Melanoma-intrinsic β-catenin signalling prevents anti-tumour immunity

(2015) Stefani Spranger et al.   NATURE

MicroRNA-125b suppresses the epithelial–mesenchymal transition and cell invasion by targeting ITGA9 in melanoma

(2015) Jie Zhang et al.   TUMOR BIOLOGY

Melanoma Induces, and Adenosine Suppresses, CXCR3-Cognate Chemokine Production and T-cell Infiltration of Lungs Bearing Metastatic-like Disease

(2015) E. Clancy-Thompson et al.   Cancer Immunology Research

A new paradigm for tumor immune escape: β-catenin-driven immune exclusion

(2015) Stefani Spranger et al.   Journal for ImmunoTherapy of Cancer

Activation, dysfunction and retention of T cells in vaccine sites after injection of incomplete Freund’s adjuvant, with or without peptide

(2013) Elise P. Salerno et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

The Continuum of Cancer Immunosurveillance: Prognostic, Predictive, and Mechanistic Signatures

(2013) Jérôme Galon et al.   IMMUNITY

Evidence for the antagonistic form of CXC-motif chemokine CXCL10 in serous epithelial ovarian tumours

(2013) Adam Rainczuk et al.   INTERNATIONAL JOURNAL OF CANCER

Persistent antigen at vaccination sites induces tumor-specific CD8+ T cell sequestration, dysfunction and deletion

(2013) Yared Hailemichael et al.   NATURE MEDICINE

Up-Regulation of PD-L1, IDO, and Tregs in the Melanoma Tumor Microenvironment Is Driven by CD8+ T Cells

(2013) S. Spranger et al.   Science Translational Medicine

Peptide Vaccination in Montanide Adjuvant Induces and GM-CSF Increases CXCR3 and Cutaneous Lymphocyte Antigen Expression by Tumor Antigen-Specific CD8 T Cells

(2013) E. Clancy-Thompson et al.   Cancer Immunology Research

Lipoprotein lipase is frequently overexpressed or translocated in cervical squamous cell carcinoma and promotes invasiveness through the non-catalytic C terminus

(2012) S A Carter et al.   BRITISH JOURNAL OF CANCER

Tryptophan Catabolism in Cancer: Beyond IDO and Tryptophan Depletion

(2012) M. Platten et al.   CANCER RESEARCH

PD-1 Blockade Enhances T-cell Migration to Tumors by Elevating IFN-  Inducible Chemokines

(2012) W. Peng et al.   CANCER RESEARCH

NF- B Hyperactivation in Tumor Tissues Allows Tumor-Selective Reprogramming of the Chemokine Microenvironment to Enhance the Recruitment of Cytolytic T Effector Cells

(2012) R. Muthuswamy et al.   CANCER RESEARCH

Immunotype and Immunohistologic Characteristics of Tumor-Infiltrating Immune Cells Are Associated with Clinical Outcome in Metastatic Melanoma

(2012) G. Erdag et al.   CANCER RESEARCH

Immune-Mediated Regression of Established B16F10 Melanoma by Intratumoral Injection of Attenuated Toxoplasma gondii Protects against Rechallenge

(2012) J. R. Baird et al.   JOURNAL OF IMMUNOLOGY

Chemotherapy Induces Intratumoral Expression of Chemokines in Cutaneous Melanoma, Favoring T-cell Infiltration and Tumor Control

(2011) M. Hong et al.   CANCER RESEARCH

The role of melanoma tumor-derived nitric oxide in the tumor inflammatory microenvironment: Its impact on the chemokine expression profile, including suppression of CXCL10

(2011) Keiji Tanese et al.   INTERNATIONAL JOURNAL OF CANCER

Randomized Multicenter Trial of the Effects of Melanoma-Associated Helper Peptides and Cyclophosphamide on the Immunogenicity of a Multipeptide Melanoma Vaccine

(2011) Craig L. Slingluff et al.   JOURNAL OF CLINICAL ONCOLOGY

K12/SECTM1, an interferon-γ regulated molecule, synergizes with CD28 to costimulate human T cell proliferation

(2011) Tao Wang et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Lipoprotein Lipase Links Dietary Fat to Solid Tumor Cell Proliferation

(2011) N. B. Kuemmerle et al.   MOLECULAR CANCER THERAPEUTICS

Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth

(2011) Kristin M Nieman et al.   NATURE MEDICINE

Poly-ICLC promotes the infiltration of effector T cells into intracranial gliomas via induction of CXCL10 in IFN-α and IFN-γ dependent manners

(2010) Xinmei Zhu et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Molecular profiling to identify relevant immune resistance mechanisms in the tumor microenvironment

(2010) Thomas F Gajewski et al.   CURRENT OPINION IN IMMUNOLOGY

Gene-expression profiling in vaccine therapy and immunotherapy for cancer

(2010) Davide Bedognetti et al.   Expert Review of Vaccines

Evidence for an antagonist form of the chemokine CXCL10 in patients chronically infected with HCV

(2010) Armanda Casrouge et al.   JOURNAL OF CLINICAL INVESTIGATION

Immunogenicity for CD8+ and CD4+ T Cells of 2 Formulations of an Incomplete Freundʼs Adjuvant for Multipeptide Melanoma Vaccines

(2010) Craig L. Slingluff et al.   JOURNAL OF IMMUNOTHERAPY

Interferons Induce CXCR3-cognate Chemokine Production by Human Metastatic Melanoma

(2010) Lynn T. Dengel et al.   JOURNAL OF IMMUNOTHERAPY

Cancer and the Complement Cascade

(2010) M. J. Rutkowski et al.   MOLECULAR CANCER RESEARCH

Chemokine Expression in Melanoma Metastases Associated with CD8+ T-Cell Recruitment

(2009) H. Harlin et al.   CANCER RESEARCH

Effect of Granulocyte/Macrophage Colony-Stimulating Factor on Circulating CD8+ and CD4+ T-Cell Responses to a Multipeptide Melanoma Vaccine: Outcome of a Multicenter Randomized Trial

(2009) C. L. Slingluff et al.   CLINICAL CANCER RESEARCH

Immune profile and mitotic index of metastatic melanoma lesions enhance clinical staging in predicting patient survival

(2009) D. Bogunovic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA