The circadian machinery links metabolic disorders and depression: A review of pathways, proteins and potential pharmacological interventions
出版年份 2020 全文链接
标题
The circadian machinery links metabolic disorders and depression: A review of pathways, proteins and potential pharmacological interventions
作者
关键词
Circadian rhythm, Central circadian clock, Clock proteins, Epigenetic modifications, Metabolic disorders, Major depressive disorder
出版物
LIFE SCIENCES
Volume 265, Issue -, Pages 118809
出版商
Elsevier BV
发表日期
2020-11-26
DOI
10.1016/j.lfs.2020.118809
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Identification of KMT2D and KDM6A variants by targeted sequencing from patients with Kabuki syndrome and other congenital disorders
- (2020) Chui-Sun Yap et al. GENE
- Pharmacological Interventions to Circadian Clocks and Their Molecular Bases
- (2020) Simon Miller et al. JOURNAL OF MOLECULAR BIOLOGY
- Virtual discovery of melatonin receptor ligands to modulate circadian rhythms
- (2020) Reed M. Stein et al. NATURE
- Dietary natural cocoa ameliorates disrupted circadian rhythms in locomotor activity and sleep-wake cycles in mice with chronic sleep disorders caused by psychophysiological stress
- (2020) Katsutaka Oishi et al. NUTRITION
- Relationship between Intrinsically Photosensitive Ganglion Cell Function and Circadian Regulation in Diabetic Retinopathy
- (2020) Sirimon Reutrakul et al. Scientific Reports
- Mechanism of Crosstalk between the LSD1 Demethylase and HDAC1 Deacetylase in the CoREST Complex
- (2020) Yun Song et al. Cell Reports
- Structure-based discovery of potent and selective melatonin receptor agonists
- (2020) Nilkanth Patel et al. eLife
- Deconstructing circadian disruption: Assessing the contribution of reduced peripheral oscillator amplitude on obesity and glucose intolerance in mice
- (2020) Vincent Vinne et al. JOURNAL OF PINEAL RESEARCH
- Isoform-selective regulation of mammalian cryptochromes
- (2020) Simon Miller et al. Nature Chemical Biology
- Nurse Health: The Influence of Chronotype and Shift Timing
- (2020) Beverly M. Hittle et al. WESTERN JOURNAL OF NURSING RESEARCH
- Melatonin: new insights on its therapeutic properties in diabetic complications
- (2020) Mohammad Hossein Pourhanifeh et al. Diabetology & Metabolic Syndrome
- Dietary Patterns of Nurses on Rotational Shifts Are Marked by Redistribution of Energy into the Nightshift
- (2020) Alan Flanagan et al. Nutrients
- Cell-based screen identifies a new potent and highly selective CK2 inhibitor for modulation of circadian rhythms and cancer cell growth
- (2019) Tsuyoshi Oshima et al. Science Advances
- BMAL1 knockout macaque monkeys display reduced sleep and psychiatric disorders
- (2019) Peiyuan Qiu et al. National Science Review
- Modulation of NMDA-Mediated Clock Resetting in the Suprachiasmatic Nuclei of mPer2Luc Mouse by Endocannabinoids
- (2019) Martin Sládek et al. Frontiers in Physiology
- Acetyltransferase p300 inhibitor reverses hypertension‐induced cardiac fibrosis
- (2019) Rahul Rai et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Circadian oscillator proteins across the kingdoms of life: structural aspects
- (2019) Reena Saini et al. BMC BIOLOGY
- Off the Clock: From Circadian Disruption to Metabolic Disease
- (2019) Eleonore Maury INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The Circadian Syndrome: is the metabolic syndrome and much more!
- (2019) P Zimmet et al. JOURNAL OF INTERNAL MEDICINE
- Discovery and Characterization of XY101, a Potent, Selective, and Orally Bioavailable RORγ Inverse Agonist for Treatment of Castration-Resistant Prostate Cancer
- (2019) Yan Zhang et al. JOURNAL OF MEDICINAL CHEMISTRY
- Countering the Modern Metabolic Disease Rampage With Ancestral Endocannabinoid System Alignment
- (2019) Ian Pepper et al. Frontiers in Endocrinology
- Insulin Resistance as a Shared Pathogenic Mechanism Between Depression and Type 2 Diabetes
- (2019) Natalia de M. Lyra e Silva et al. Frontiers in Psychiatry
- Role of Food Phytochemicals in the Modulation of Circadian Clocks
- (2019) Fuguo Liu et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Resveratrol Prevents Acrylamide-Induced Mitochondrial Dysfunction and Inflammatory Responses via Targeting Circadian Regulator Bmal1 and Cry1 in Hepatocytes
- (2019) Xintong Tan et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Effects of Piceatannol and Resveratrol on Sirtuins and Hepatic Inflammation in High-Fat Diet-Fed Mice
- (2019) Hee Jae Lee et al. JOURNAL OF MEDICINAL FOOD
- The Sleep-Immune Crosstalk in Health and Disease
- (2019) Luciana Besedovsky et al. PHYSIOLOGICAL REVIEWS
- Harnessing the HDAC–histone deacetylase enzymes, inhibitors and how these can be utilised in tissue engineering
- (2019) Liam Lawlor et al. International Journal of Oral Science
- Extra Virgin Olive Oil Contains a Phenolic Inhibitor of the Histone Demethylase LSD1/KDM1A
- (2019) Elisabet Cuyàs et al. Nutrients
- Role of Proinflammatory Cytokines in Feedback Modulation of Circadian Clock Gene Rhythms by Saturated Fatty Acids
- (2019) Sam-Moon Kim et al. Scientific Reports
- Efficacy of Esketamine Nasal Spray Plus Oral Antidepressant Treatment for Relapse Prevention in Patients With Treatment-Resistant Depression
- (2019) Ella J. Daly et al. JAMA Psychiatry
- Autokinase Activity of Casein Kinase 1 δ/ε Governs the Period of Mammalian Circadian Rhythms
- (2019) Gaili Guo et al. JOURNAL OF BIOLOGICAL RHYTHMS
- Carcinogenicity of night shift work
- (2019) Elizabeth M Ward et al. LANCET ONCOLOGY
- Resveratrol Maintains Lipid Metabolism Homeostasis via One of the Mechanisms Associated with the Key Circadian Regulator Bmal1
- (2019) Jing Li et al. MOLECULES
- 3,4-Dibromo-7-Azaindole Modulates Arabidopsis Circadian Clock by Inhibiting Casein Kinase 1 Activity
- (2019) Azusa Ono et al. PLANT AND CELL PHYSIOLOGY
- The intestinal microbiota programs diurnal rhythms in host metabolism through histone deacetylase 3
- (2019) Zheng Kuang et al. SCIENCE
- Blue Light disrupts the circadian rhythm and create damage in skin cells
- (2019) Kelly Dong et al. INTERNATIONAL JOURNAL OF COSMETIC SCIENCE
- New Insights Into the Circadian Rhythm and Its Related Diseases
- (2019) Yanling Xie et al. Frontiers in Physiology
- Oolong Tea Polyphenols Ameliorate Circadian Rhythm of Intestinal Microbiome and Liver Clock Genes in Mouse Model
- (2019) Tongtong Guo et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Quercetin, caffeic acid and resveratrol regulate circadian clock genes and aging-related genes in young and old human lung fibroblast cells
- (2019) Yoshinori Okada et al. MOLECULAR BIOLOGY REPORTS
- The cellular and molecular basis of major depressive disorder: towards a unified model for understanding clinical depression
- (2019) Eleni Pitsillou et al. MOLECULAR BIOLOGY REPORTS
- Linking type 2 diabetes mellitus, cardiac hypertrophy and depression in a diurnal animal model
- (2019) Carmel Bilu et al. Scientific Reports
- LSD1/KDM1A inhibitors in clinical trials: advances and prospects
- (2019) Yuan Fang et al. Journal of Hematology & Oncology
- Dopamine D2 receptor signaling modulates pancreatic beta cell circadian rhythms
- (2019) Heather Wei et al. PSYCHONEUROENDOCRINOLOGY
- Structural basis for the activation and inhibition of Sirtuin 6 by quercetin and its derivatives
- (2019) Weijie You et al. Scientific Reports
- Differentiating external zeitgeber impact on peripheral circadian clock resetting
- (2019) Isabel Heyde et al. Scientific Reports
- Pituitary Adenylate Cyclase-Activating Peptide (PACAP)-Glutamate Co-transmission Drives Circadian Phase-Advancing Responses to Intrinsically Photosensitive Retinal Ganglion Cell Projections by Suprachiasmatic Nucleus
- (2019) Peder T. Lindberg et al. Frontiers in Neuroscience
- Pharmacological blockade of PCAF ameliorates osteoarthritis development via dual inhibition of TNF-α-driven inflammation and ER stress
- (2019) Deheng Chen et al. EBioMedicine
- Nobiletin protects against insulin resistance and disorders of lipid metabolism by reprogramming of circadian clock in hepatocytes
- (2018) Guoyuan Qi et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Design and synthesis of a biaryl series as inhibitors for the bromodomains of CBP/P300
- (2018) Kwong Wah Lai et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- ORY-1001, a Potent and Selective Covalent KDM1A Inhibitor, for the Treatment of Acute Leukemia
- (2018) Tamara Maes et al. CANCER CELL
- Modulating the masters: chemical tools to dissect CBP and p300 function
- (2018) Meghan E Breen et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- Circadian clock component REV-ERBα controls homeostatic regulation of pulmonary inflammation
- (2018) Marie Pariollaud et al. JOURNAL OF CLINICAL INVESTIGATION
- The cryptochrome inhibitor KS15 enhances E-box-mediated transcription by disrupting the feedback action of a circadian transcription-repressor complex
- (2018) Jaebong Jang et al. LIFE SCIENCES
- Pathophysiology of Depression: Molecular Regulation of Melatonin Homeostasis – Current Status
- (2018) Monika Dmitrzak-Weglarz et al. NEUROPSYCHOBIOLOGY
- Chronopathophysiological implications of orexin in sleep disturbances and lifestyle-related disorders
- (2018) Hiroshi Tsuneki et al. PHARMACOLOGY & THERAPEUTICS
- 0041 Circadian Misalignment Increases The Desire For Food Intake In Chronic Shift Workers
- (2018) J Qian et al. SLEEP
- Exercise, Obesity and CNS Control of Metabolic Homeostasis: A Review
- (2018) John K. Smith Frontiers in Physiology
- 0041 Circadian Misalignment Increases The Desire For Food Intake In Chronic Shift Workers
- (2018) J Qian et al. SLEEP
- Structure based identification and biological evaluation of novel and potent inhibitors of PCAF catalytic domain
- (2018) Venkatesan Suryanarayanan et al. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
- Ghrelin is impacted by the endogenous circadian system and by circadian misalignment in humans
- (2018) Jingyi Qian et al. INTERNATIONAL JOURNAL OF OBESITY
- Cichoric Acid Prevents Free-Fatty-Acid-Induced Lipid Metabolism Disorders via Regulating Bmal1 in HepG2 Cells
- (2018) Rui Guo et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- The Phosphorylation of CREB at Serine 133 Is a Key Event for Circadian Clock Timing and Entrainment in the Suprachiasmatic Nucleus
- (2018) Kelin L. Wheaton et al. JOURNAL OF BIOLOGICAL RHYTHMS
- Melatonin and inflammation - story of a double-edged blade
- (2018) Rüdiger Hardeland JOURNAL OF PINEAL RESEARCH
- Inhibitor of CBP Histone Acetyltransferase Downregulates p53 Activation and Facilitates Methylation at Lysine 27 on Histone H3
- (2018) Adam Vincek et al. MOLECULES
- OUP accepted manuscript
- (2018) Advances in Nutrition
- Tea polyphenols direct Bmal1-driven ameliorating of the redox imbalance and mitochondrial dysfunction in hepatocytes
- (2018) Guoyuan Qi et al. FOOD AND CHEMICAL TOXICOLOGY
- Pharmacological Inhibition of LSD1 for Cancer Treatment
- (2018) Guan-Jun Yang et al. MOLECULES
- Circadian clocks and insulin resistance
- (2018) Dirk Jan Stenvers et al. Nature Reviews Endocrinology
- The Role of Microbiome in Insomnia, Circadian Disturbance and Depression
- (2018) Yuanyuan Li et al. Frontiers in Psychiatry
- Tea polyphenols ameliorates neural redox imbalance and mitochondrial dysfunction via mechanisms linking the key circadian regular Bmal1
- (2017) Guoyuan Qi et al. FOOD AND CHEMICAL TOXICOLOGY
- Diurnal Hypothalamic-Pituitary-Adrenal Axis Measures and Inflammatory Marker Correlates in Major Depressive Disorder
- (2017) Kelly Doolin et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- GNE-781, A Highly Advanced Potent and Selective Bromodomain Inhibitor of Cyclic Adenosine Monophosphate Response Element Binding Protein, Binding Protein (CBP)
- (2017) F. Anthony Romero et al. JOURNAL OF MEDICINAL CHEMISTRY
- Thieno[3,2-b]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1. Part 1: High-Throughput Screening and Preliminary Exploration
- (2017) Luca Sartori et al. JOURNAL OF MEDICINAL CHEMISTRY
- Association between light at night, melatonin secretion, sleep deprivation, and the internal clock: Health impacts and mechanisms of circadian disruption
- (2017) Yvan Touitou et al. LIFE SCIENCES
- Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours
- (2017) Loren M. Lasko et al. NATURE
- Lifestyle recommendations for the prevention and management of metabolic syndrome: an international panel recommendation
- (2017) Pablo Pérez-Martínez et al. NUTRITION REVIEWS
- Epigenetic mechanisms of major depression: Targeting neuronal plasticity
- (2017) Shusaku Uchida et al. PSYCHIATRY AND CLINICAL NEUROSCIENCES
- Circadian phase, dynamics of subjective sleepiness and sensitivity to blue light in young adults complaining of a delayed sleep schedule
- (2017) Christophe Moderie et al. SLEEP MEDICINE
- Dietary tea polyphenols ameliorate metabolic syndrome and memory impairment via circadian clock related mechanisms
- (2017) Guoyuan Qi et al. Journal of Functional Foods
- RORα controls hepatic lipid homeostasis via negative regulation of PPARγ transcriptional network
- (2017) Kyeongkyu Kim et al. Nature Communications
- Clock-Enhancing Small Molecules and Potential Applications in Chronic Diseases and Aging
- (2017) Gabrielle F. Gloston et al. Frontiers in Neurology
- Potent Effects of Flavonoid Nobiletin on Amplitude, Period, and Phase of the Circadian Clock Rhythm in PER2::LUCIFERASE Mouse Embryonic Fibroblasts
- (2017) Ayako Shinozaki et al. PLoS One
- Sleep Disturbance, Sleep Duration, and Inflammation: A Systematic Review and Meta-Analysis of Cohort Studies and Experimental Sleep Deprivation
- (2016) Michael R. Irwin et al. BIOLOGICAL PSYCHIATRY
- Baicalin, a natural LSD1 inhibitor
- (2016) Yi-Chao Zheng et al. BIOORGANIC CHEMISTRY
- The Small Molecule Nobiletin Targets the Molecular Oscillator to Enhance Circadian Rhythms and Protect against Metabolic Syndrome
- (2016) Baokun He et al. Cell Metabolism
- Phase shifts in circadian peripheral clocks caused by exercise are dependent on the feeding schedule in PER2::LUC mice
- (2016) Hiroyuki Sasaki et al. CHRONOBIOLOGY INTERNATIONAL
- Protective effect of blue-light shield eyewear for adults against light pollution from self-luminous devices used at night
- (2016) Masahiko Ayaki et al. CHRONOBIOLOGY INTERNATIONAL
- Brain-derived Neurotrophic Factor (BDNF)-TrkB Signaling in Inflammation-related Depression and Potential Therapeutic Targets
- (2016) Ji-chun Zhang et al. Current Neuropharmacology
- Inflammation in Depression and the Potential for Anti-Inflammatory Treatment
- (2016) Ole Kohler et al. Current Neuropharmacology
- A functional circadian clock is required for proper insulin secretion by human pancreatic islet cells
- (2016) C. Saini et al. DIABETES OBESITY & METABOLISM
- Chronotherapy: Intuitive, Sound, Founded…But Not Broadly Applied
- (2016) Julia M. Selfridge et al. DRUGS
- Circadian Rhythm and Sleep Disruption: Causes, Metabolic Consequences, and Countermeasures
- (2016) Gregory D. M. Potter et al. ENDOCRINE REVIEWS
- Melatonin receptors as therapeutic targets in the suprachiasmatic nucleus
- (2016) Paul Pévet EXPERT OPINION ON THERAPEUTIC TARGETS
- Ketamine: NMDA Receptors and Beyond
- (2016) C. F. Zorumski et al. JOURNAL OF NEUROSCIENCE
- Short-term feeding at the wrong time is sufficient to desynchronize peripheral clocks and induce obesity with hyperphagia, physical inactivity and metabolic disorders in mice
- (2016) Yuki Yasumoto et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- HPA axis in major depression: cortisol, clinical symptomatology and genetic variation predict cognition
- (2016) J Keller et al. MOLECULAR PSYCHIATRY
- Transcriptional architecture of the mammalian circadian clock
- (2016) Joseph S. Takahashi NATURE REVIEWS GENETICS
- Distinct Roles of HDAC3 in the Core Circadian Negative Feedback Loop Are Critical for Clock Function
- (2016) Guangsen Shi et al. Cell Reports
- NPAS2 Compensates for Loss of CLOCK in Peripheral Circadian Oscillators
- (2016) Dominic Landgraf et al. PLoS Genetics
- The Relationship Between Depression and Metabolic Syndrome: Systematic Review and Meta-Analysis Study
- (2016) Reza Ghanei Gheshlagh et al. Iranian Red Crescent Medical Journal
- Specific Direct Small Molecule p300/β-Catenin Antagonists Maintain Stem Cell Potency
- (2016) Yusuke Higuchi et al. Current Molecular Pharmacology
- CH Activation Generates Period-Shortening Molecules That Target Cryptochrome in the Mammalian Circadian Clock
- (2015) Tsuyoshi Oshima et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Royal Australian and New Zealand College of Psychiatrists clinical practice guidelines for mood disorders
- (2015) Gin S Malhi et al. AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY
- Time-fixed feeding prevents obesity induced by chronic advances of light/dark cycles in mouse models of jet-lag/shift work
- (2015) Hideaki Oike et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Resveratrol restores the circadian rhythmic disorder of lipid metabolism induced by high-fat diet in mice
- (2015) Linjie Sun et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- A DNA Hypomethylation Signature Predicts Antitumor Activity of LSD1 Inhibitors in SCLC
- (2015) Helai P. Mohammad et al. CANCER CELL
- Generation of a Selective Small Molecule Inhibitor of the CBP/p300 Bromodomain for Leukemia Therapy
- (2015) S. Picaud et al. CANCER RESEARCH
- Development of Small-Molecule Cryptochrome Stabilizer Derivatives as Modulators of the Circadian Clock
- (2015) Jae Wook Lee et al. ChemMedChem
- ROR Inverse Agonist Suppresses Insulitis and Prevents Hyperglycemia in a Mouse Model of Type 1 Diabetes
- (2015) Laura A. Solt et al. ENDOCRINOLOGY
- Gene discovery for Mendelian conditions via social networking: de novo variants in KDM1A cause developmental delay and distinctive facial features
- (2015) Jessica X. Chong et al. GENETICS IN MEDICINE
- 3-(Piperidin-4-ylmethoxy)pyridine Containing Compounds Are Potent Inhibitors of Lysine Specific Demethylase 1
- (2015) Fangrui Wu et al. JOURNAL OF MEDICINAL CHEMISTRY
- Chronic consumption of dietary proanthocyanidins modulates peripheral clocks in healthy and obese rats
- (2015) A. Ribas-Latre et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- Histone Deacetylase Inhibitors in Clinical Studies as Templates for New Anticancer Agents
- (2015) Madhusoodanan Mottamal et al. MOLECULES
- NAD+-SIRT1 control of H3K4 trimethylation through circadian deacetylation of MLL1
- (2015) Lorena Aguilar-Arnal et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- CBP30, a selective CBP/p300 bromodomain inhibitor, suppresses human Th17 responses
- (2015) Ariane Hammitzsch et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Effects of caffeine on the human circadian clock in vivo and in vitro
- (2015) Tina M. Burke et al. Science Translational Medicine
- Circadian Clocks as Modulators of Metabolic Comorbidity in Psychiatric Disorders
- (2015) Rita Barandas et al. Current Psychiatry Reports
- NAD+-SIRT1 control of H3K4 trimethylation through circadian deacetylation of MLL1
- (2015) Lorena Aguilar-Arnal et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Inhibition of lysine-specific demethylase 1 by the acyclic diterpenoid geranylgeranoic acid and its derivatives
- (2014) Chiharu Sakane et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Mechanisms of Glucocorticoid-Induced Insulin Resistance
- (2014) Eliza B. Geer et al. ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA
- The light-dark cycle controls peripheral rhythmicity in mice with a genetically ablated suprachiasmatic nucleus clock
- (2014) Jana Husse et al. FASEB JOURNAL
- Discovery of Novel and Selective SIRT6 Inhibitors
- (2014) Marco Daniele Parenti et al. JOURNAL OF MEDICINAL CHEMISTRY
- Phosphorylation of LSD1 by PKCα Is Crucial for Circadian Rhythmicity and Phase Resetting
- (2014) Hye Jin Nam et al. MOLECULAR CELL
- Circadian dysregulation of clock genes: clues to rapid treatments in major depressive disorder
- (2014) B G Bunney et al. MOLECULAR PSYCHIATRY
- Light as a central modulator of circadian rhythms, sleep and affect
- (2014) Tara A. LeGates et al. NATURE REVIEWS NEUROSCIENCE
- Dual inhibition of REV-ERBβ and autophagy as a novel pharmacological approach to induce cytotoxicity in cancer cells
- (2014) C De Mei et al. ONCOGENE
- Chromatin landscape and circadian dynamics: Spatial and temporal organization of clock transcription
- (2014) Lorena Aguilar-Arnal et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Evening use of light-emitting eReaders negatively affects sleep, circadian timing, and next-morning alertness
- (2014) Anne-Marie Chang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- SIRT1 and other sirtuins in metabolism
- (2014) Hung-Chun Chang et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Effects of resveratrol on changes induced by high-fat feeding on clock genes in rats
- (2013) Jonatan Miranda et al. BRITISH JOURNAL OF NUTRITION
- Crosstalk between lysine-specific demethylase 1 (LSD1) and histone deacetylases mediates antineoplastic efficacy of HDAC inhibitors in human breast cancer cells
- (2013) Shauna N. Vasilatos et al. CARCINOGENESIS
- FBXL21 Regulates Oscillation of the Circadian Clock through Ubiquitination and Stabilization of Cryptochromes
- (2013) Arisa Hirano et al. CELL
- The hypothalamus and metabolism: integrating signals to control energy and glucose homeostasis
- (2013) Anthony P Coll et al. CURRENT OPINION IN PHARMACOLOGY
- Improving Insulin Sensitivity With HDAC Inhibitor
- (2013) J. Ye DIABETES
- Optimized Chemical Probes for REV-ERBα
- (2013) Ryan P. Trump et al. JOURNAL OF MEDICINAL CHEMISTRY
- The 2.5 Å Crystal Structure of the SIRT1 Catalytic Domain Bound to Nicotinamide Adenine Dinucleotide (NAD+) and an Indole (EX527 Analogue) Reveals a Novel Mechanism of Histone Deacetylase Inhibition
- (2013) Xun Zhao et al. JOURNAL OF MEDICINAL CHEMISTRY
- Phosphorylation of neuronal Lysine-Specific Demethylase 1LSD1/KDM1A impairs transcriptional repression by regulating interaction with CoREST and histone deacetylases HDAC1/2
- (2013) Emanuela Toffolo et al. JOURNAL OF NEUROCHEMISTRY
- Using Standardized fMRI Protocols to Identify Patterns of Prefrontal Circuit Dysregulation that are Common and Specific to Cognitive and Emotional Tasks in Major Depressive Disorder: First Wave Results from the iSPOT-D Study
- (2013) Mayuresh S Korgaonkar et al. NEUROPSYCHOPHARMACOLOGY
- Involvement of the Clock Gene Rev-erb alpha in the Regulation of Glucagon Secretion in Pancreatic Alpha-Cells
- (2013) Elaine Vieira et al. PLoS One
- Circadian patterns of gene expression in the human brain and disruption in major depressive disorder
- (2013) J. Z. Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pharmacological modulation of circadian rhythms by synthetic activators of the deacetylase SIRT1
- (2013) Marina M. Bellet et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Identification of a Selective RORγ Ligand That Suppresses TH17 Cells and Stimulates T Regulatory Cells
- (2012) Laura A. Solt et al. ACS Chemical Biology
- Identification of SR2211: A Potent Synthetic RORγ-Selective Modulator
- (2012) Naresh Kumar et al. ACS Chemical Biology
- The circadian clock transcriptional complex: metabolic feedback intersects with epigenetic control
- (2012) Selma Masri et al. Annals of the New York Academy of Sciences
- Circadian Rhythm Connections to Oxidative Stress: Implications for Human Health
- (2012) Melissa Wilking et al. ANTIOXIDANTS & REDOX SIGNALING
- Autonomous and self-sustained circadian oscillators displayed in human islet cells
- (2012) P. Pulimeno et al. DIABETOLOGIA
- Regulation of core clock genes in human islets
- (2012) Jelena A. Stamenkovic et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists
- (2012) Laura A. Solt et al. NATURE
- Structure of HDAC3 bound to co-repressor and inositol tetraphosphate
- (2012) Peter J. Watson et al. NATURE
- Hepatic Hdac3 promotes gluconeogenesis by repressing lipid synthesis and sequestration
- (2012) Zheng Sun et al. NATURE MEDICINE
- Perampanel—new promise for refractory epilepsy?
- (2012) Wolfgang Löscher et al. Nature Reviews Neurology
- Identification of Small Molecule Activators of Cryptochrome
- (2012) T. Hirota et al. SCIENCE
- Nutrient sensing and the circadian clock
- (2012) Clara B. Peek et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Identification of Potent and Selective Diphenylpropanamide RORγ Inhibitors
- (2012) Jun R. Huh et al. ACS Medicinal Chemistry Letters
- Inhibition of GSK3 by lithium, from single molecules to signaling networks
- (2012) Laure Freland et al. Frontiers in Molecular Neuroscience
- Discovery of 3-Substituted Aminocyclopentanes as Potent and Orally Bioavailable NR2B Subtype-Selective NMDA Antagonists
- (2011) Mark E. Layton et al. ACS Chemical Neuroscience
- Deletion of KDM6A, a Histone Demethylase Interacting with MLL2, in Three Patients with Kabuki Syndrome
- (2011) Damien Lederer et al. AMERICAN JOURNAL OF HUMAN GENETICS
- A Small Molecule Modulates Circadian Rhythms through Phosphorylation of the Period Protein
- (2011) Jae Wook Lee et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Type 1 diabetes mellitus and major depressive disorder: evidence for a biological link
- (2011) D. J. Korczak et al. DIABETOLOGIA
- Modelling the dual role of Per phosphorylation and its effect on the period and phase of the mammalian circadian clock
- (2011) J.-C. Leloup et al. IET Systems Biology
- Ursolic Acid Suppresses Interleukin-17 (IL-17) Production by Selectively Antagonizing the Function of RORγt Protein
- (2011) Tao Xu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Resveratrol Dietary Supplementation Shortens the Free-Running Circadian Period and Decreases Body Temperature in a Prosimian Primate
- (2011) Fabien Pifferi et al. JOURNAL OF BIOLOGICAL RHYTHMS
- Melatonin and its analogs in insomnia and depression
- (2011) Daniel P. Cardinali et al. JOURNAL OF PINEAL RESEARCH
- Photoentrainment and pupillary light reflex are mediated by distinct populations of ipRGCs
- (2011) S.-K. Chen et al. NATURE
- Digoxin and its derivatives suppress TH17 cell differentiation by antagonizing RORγt activity
- (2011) Jun R. Huh et al. NATURE
- Ketamine Influences CLOCK:BMAL1 Function Leading to Altered Circadian Gene Expression
- (2011) Marina M. Bellet et al. PLoS One
- The period of the circadian oscillator is primarily determined by the balance between casein kinase 1 and protein phosphatase 1
- (2011) H.-m. Lee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Histone Lysine Demethylase JARID1a Activates CLOCK-BMAL1 and Influences the Circadian Clock
- (2011) L. DiTacchio et al. SCIENCE
- GSK4112, a Small Molecule Chemical Probe for the Cell Biology of the Nuclear Heme Receptor Rev-erbα
- (2010) Daniel Grant et al. ACS Chemical Biology
- Identification of SR1078, a Synthetic Agonist for the Orphan Nuclear Receptors RORα and RORγ
- (2010) Yongjun Wang et al. ACS Chemical Biology
- Identification of SR8278, a Synthetic Antagonist of the Nuclear Heme Receptor REV-ERB
- (2010) Douglas Kojetin et al. ACS Chemical Biology
- Identification of SR3335 (ML-176): A Synthetic RORα Selective Inverse Agonist
- (2010) Naresh Kumar et al. ACS Chemical Biology
- Structurally Designedtrans-2-Phenylcyclopropylamine Derivatives Potently Inhibit Histone Demethylase LSD1/KDM1,,§
- (2010) Shinya Mimasu et al. BIOCHEMISTRY
- A second class of nuclear receptors for oxysterols: Regulation of RORα and RORγ activity by 24S-hydroxycholesterol (cerebrosterol)
- (2010) Yongjun Wang et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- CX-4945, an Orally Bioavailable Selective Inhibitor of Protein Kinase CK2, Inhibits Prosurvival and Angiogenic Signaling and Exhibits Antitumor Efficacy
- (2010) A. Siddiqui-Jain et al. CANCER RESEARCH
- Virtual Ligand Screening of the p300/CBP Histone Acetyltransferase: Identification of a Selective Small Molecule Inhibitor
- (2010) Erin M. Bowers et al. CHEMISTRY & BIOLOGY
- Coactivation of the CLOCK-BMAL1 complex by CBP mediates resetting of the circadian clock
- (2010) Y. Lee et al. JOURNAL OF CELL SCIENCE
- Alternative Splicing of the Histone Demethylase LSD1/KDM1 Contributes to the Modulation of Neurite Morphogenesis in the Mammalian Nervous System
- (2010) C. Zibetti et al. JOURNAL OF NEUROSCIENCE
- Chronic Inflammation in Obesity and the Metabolic Syndrome
- (2010) Rosário Monteiro et al. MEDIATORS OF INFLAMMATION
- Structural Basis for Hydroxycholesterols as Natural Ligands of Orphan Nuclear Receptor RORγ
- (2010) Lihua Jin et al. MOLECULAR ENDOCRINOLOGY
- Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes
- (2010) Biliana Marcheva et al. NATURE
- Exome sequencing identifies MLL2 mutations as a cause of Kabuki syndrome
- (2010) Sarah B Ng et al. NATURE GENETICS
- The histone methyltransferase MLL1 permits the oscillation of circadian gene expression
- (2010) Sayako Katada et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Casein Kinase 1 Delta (CK1δ) Regulates Period Length of the Mouse Suprachiasmatic Circadian Clock In Vitro
- (2010) Jean-Pierre Etchegaray et al. PLoS One
- Harmonizing the Metabolic Syndrome
- (2009) K.G.M.M. Alberti et al. CIRCULATION
- Modulation of Retinoic Acid Receptor-related Orphan Receptor α and γ Activity by 7-Oxygenated Sterol Ligands
- (2009) Yongjun Wang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Selective Inhibition of Casein Kinase 1 Minimally Alters Circadian Clock Period
- (2009) K. M. Walton et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Gallic Acid Suppresses Lipopolysaccharide-Induced Nuclear Factor- B Signaling by Preventing RelA Acetylation in A549 Lung Cancer Cells
- (2009) K.-C. Choi et al. MOLECULAR CANCER RESEARCH
- The Benzenesulfoamide T0901317 [N-(2,2,2-Trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-benzenesulfonamide] Is a Novel Retinoic Acid Receptor-Related Orphan Receptor- / Inverse Agonist
- (2009) N. Kumar et al. MOLECULAR PHARMACOLOGY
- AMPK Regulates the Circadian Clock by Cryptochrome Phosphorylation and Degradation
- (2009) K. A. Lamia et al. SCIENCE
- CBP/p300 is a cell type-specific modulator of CLOCK/BMAL1-mediated transcription
- (2009) Hiroshi Hosoda et al. Molecular Brain
- SIRT1 Regulates Circadian Clock Gene Expression through PER2 Deacetylation
- (2008) Gad Asher et al. CELL
- Depression: An Important Comorbidity With Metabolic Syndrome in a General Population
- (2008) J. A. Dunbar et al. DIABETES CARE
- Adrenal peripheral clock controls the autonomous circadian rhythm of glucocorticoid by causing rhythmic steroid production
- (2008) G. H. Son et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started